ATE171447T1 - Benzimidazole derivate - Google Patents
Benzimidazole derivateInfo
- Publication number
- ATE171447T1 ATE171447T1 AT94909233T AT94909233T ATE171447T1 AT E171447 T1 ATE171447 T1 AT E171447T1 AT 94909233 T AT94909233 T AT 94909233T AT 94909233 T AT94909233 T AT 94909233T AT E171447 T1 ATE171447 T1 AT E171447T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- date sep
- benzimidazole derivatives
- sec
- pub
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939305628A GB9305628D0 (en) | 1993-03-18 | 1993-03-18 | Therapeutic agents |
GB939316258A GB9316258D0 (en) | 1993-08-05 | 1993-08-05 | Therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE171447T1 true ATE171447T1 (de) | 1998-10-15 |
Family
ID=26302612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94909233T ATE171447T1 (de) | 1993-03-18 | 1994-03-16 | Benzimidazole derivate |
Country Status (9)
Country | Link |
---|---|
US (1) | US5714498A (de) |
EP (1) | EP0689535B1 (de) |
JP (1) | JPH08508030A (de) |
AT (1) | ATE171447T1 (de) |
AU (1) | AU679045B2 (de) |
CA (1) | CA2156836A1 (de) |
DE (1) | DE69413523T2 (de) |
ES (1) | ES2121193T3 (de) |
WO (1) | WO1994021615A1 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9604036D0 (en) * | 1996-02-26 | 1996-04-24 | Merck Sharp & Dohme | Therapeutic agents |
US6187774B1 (en) * | 1996-03-04 | 2001-02-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused heterocyclic compounds and pharmaceutical applications thereof |
GB9605065D0 (en) * | 1996-03-11 | 1996-05-08 | Merck Sharp & Dohme | Therapeutic agents |
US5846982A (en) * | 1996-06-14 | 1998-12-08 | Eli Lilly And Company | Inhibition of serotonin reuptake |
DK1065205T3 (da) | 1998-03-18 | 2003-06-23 | Taisho Pharmaceutical Co Ltd | Heteroaromatiske derivater |
EP1070715A4 (de) | 1998-03-19 | 2002-10-17 | Nihon Nohyaku Co Ltd | Arylpiperidine und ihre verwendung |
US6867209B1 (en) | 1998-05-22 | 2005-03-15 | Scios, Inc. | Indole-type derivatives as inhibitors of p38 kinase |
US6448257B1 (en) | 1998-05-22 | 2002-09-10 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6340685B1 (en) | 1998-05-22 | 2002-01-22 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6589954B1 (en) * | 1998-05-22 | 2003-07-08 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
US6130235A (en) * | 1998-05-22 | 2000-10-10 | Scios Inc. | Compounds and methods to treat cardiac failure and other disorders |
IL146309A (en) | 1999-05-21 | 2008-03-20 | Scios Inc | Derivatives of the indole type and pharmaceutical preparations containing them as inhibitors of kinase p38 |
JP2003512422A (ja) * | 1999-10-29 | 2003-04-02 | メルク シャープ エンド ドーム リミテッド | ベンズイミダゾールnmda/nr2bアンタゴニストを使用する疼痛の治療方法 |
US6291499B1 (en) * | 1999-10-29 | 2001-09-18 | Merck & Co., Inc. | 2-cyclohexyl benzimidazole NMDA/NR2B antagonists |
US6432976B1 (en) * | 1999-10-29 | 2002-08-13 | Merck & Co., Inc. | 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists |
US6380205B1 (en) | 1999-10-29 | 2002-04-30 | Merck & Co., Inc. | 2-cyclohexyl quinazoline NMDA/NR2B antagonists |
US6369076B1 (en) | 1999-10-29 | 2002-04-09 | Merck & Co. Inc. | 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists |
US6495561B2 (en) | 1999-10-29 | 2002-12-17 | Merck & Co., Inc. | 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists |
US6489477B1 (en) | 1999-10-29 | 2002-12-03 | Merck & Co., Inc. | 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists |
US6476041B1 (en) * | 1999-10-29 | 2002-11-05 | Merck & Co., Inc. | 1,4 substituted piperidinyl NMDA/NR2B antagonists |
US6316474B1 (en) * | 1999-10-29 | 2001-11-13 | Merck & Co., Inc. | 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists |
US7842068B2 (en) * | 2000-12-07 | 2010-11-30 | Integrated Vascular Systems, Inc. | Apparatus and methods for providing tactile feedback while delivering a closure device |
US6806275B2 (en) | 2000-09-13 | 2004-10-19 | Nihon Nohyaku Co., Ltd. | Arylpiperidine derivatives and use thereof |
EP1379520B2 (de) | 2001-02-23 | 2014-04-09 | Merck Sharp & Dohme Corp. | N-substituierte nichtaryl-heterocyclische nmda/nr2b antagonisten |
US7022728B2 (en) * | 2001-03-09 | 2006-04-04 | Abbott Laboratories | Benzimidazoles that are useful in treating male sexual dysfunction |
US6960589B2 (en) * | 2001-03-09 | 2005-11-01 | Abbott Laboratories | Benzimidazoles that are useful in treating sexual dysfunction |
AU2002338334B8 (en) | 2001-04-03 | 2008-09-18 | Merck & Co., Inc. | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B antagonists |
US20040127504A1 (en) * | 2002-09-06 | 2004-07-01 | Cowart Marlon D. | Benzimidazoles that are useful in treating sexual dysfunction |
US7592360B2 (en) | 2003-06-04 | 2009-09-22 | Merck & Co., Inc. | 3-fluoro-piperidines as NMDA/NR2B antagonists |
GB0503646D0 (en) * | 2005-02-22 | 2005-03-30 | Novartis Ag | Organic compounds |
GB0508318D0 (en) * | 2005-04-25 | 2005-06-01 | Novartis Ag | Organic compounds |
GB0508314D0 (en) * | 2005-04-25 | 2005-06-01 | Novartis Ag | Organic compounds |
GB0508319D0 (en) * | 2005-04-25 | 2005-06-01 | Novartis Ag | Organic compounds |
WO2012087833A1 (en) | 2010-12-22 | 2012-06-28 | Abbott Laboratories | Hepatitis c inhibitors and uses thereof |
TWI707683B (zh) | 2018-06-13 | 2020-10-21 | 美商輝瑞股份有限公司 | Glp-1受體促效劑及其用途 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1417745A (en) * | 1973-07-07 | 1975-12-17 | Beecham Group Ltd | Chromene compounds |
EP0034249B1 (de) * | 1980-02-08 | 1984-10-24 | Gruppo Lepetit S.P.A. | Naphthimidazol- und Naphthoxazol-Derivate, ihre Herstellung und ihre Verwendung in Pharmazeutika |
PH23995A (en) * | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
JP2643168B2 (ja) * | 1987-08-24 | 1997-08-20 | エーザイ株式会社 | 不整脈治療・予防剤 |
CA2022451C (en) * | 1989-08-03 | 2001-01-23 | Albert Anthony Carr | Anti-psychotic piperidynl benzimidazole compounds |
US5169855A (en) * | 1990-03-28 | 1992-12-08 | Du Pont Merck Pharmaceutical Company | Piperidine ether derivatives as psychotropic drugs or plant fungicides |
-
1994
- 1994-03-16 EP EP94909233A patent/EP0689535B1/de not_active Expired - Lifetime
- 1994-03-16 DE DE69413523T patent/DE69413523T2/de not_active Expired - Fee Related
- 1994-03-16 US US08/530,099 patent/US5714498A/en not_active Expired - Fee Related
- 1994-03-16 CA CA002156836A patent/CA2156836A1/en not_active Abandoned
- 1994-03-16 AT AT94909233T patent/ATE171447T1/de not_active IP Right Cessation
- 1994-03-16 AU AU62156/94A patent/AU679045B2/en not_active Ceased
- 1994-03-16 JP JP6520781A patent/JPH08508030A/ja active Pending
- 1994-03-16 ES ES94909233T patent/ES2121193T3/es not_active Expired - Lifetime
- 1994-03-16 WO PCT/GB1994/000528 patent/WO1994021615A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
DE69413523D1 (de) | 1998-10-29 |
US5714498A (en) | 1998-02-03 |
AU679045B2 (en) | 1997-06-19 |
EP0689535B1 (de) | 1998-09-23 |
ES2121193T3 (es) | 1998-11-16 |
JPH08508030A (ja) | 1996-08-27 |
AU6215694A (en) | 1994-10-11 |
EP0689535A1 (de) | 1996-01-03 |
CA2156836A1 (en) | 1994-09-29 |
DE69413523T2 (de) | 1999-05-12 |
WO1994021615A1 (en) | 1994-09-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
REN | Ceased due to non-payment of the annual fee |