DE3030612C2 - - Google Patents

Info

Publication number
DE3030612C2
DE3030612C2 DE3030612A DE3030612A DE3030612C2 DE 3030612 C2 DE3030612 C2 DE 3030612C2 DE 3030612 A DE3030612 A DE 3030612A DE 3030612 A DE3030612 A DE 3030612A DE 3030612 C2 DE3030612 C2 DE 3030612C2
Authority
DE
Germany
Prior art keywords
cis
compound
general formula
hexahydro
melting point
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3030612A
Other languages
German (de)
English (en)
Other versions
DE3030612A1 (de
Inventor
Bareth John Luton Bedforshire Gb Thomas
Michael John Baldock Hertfordshire Gb Broadhurst
Cedric Herbert Hatfield Hertfordshire Gb Hassall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE3030612A1 publication Critical patent/DE3030612A1/de
Application granted granted Critical
Publication of DE3030612C2 publication Critical patent/DE3030612C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/567—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with sulfur as the only hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19803030612 1979-08-20 1980-08-13 Naphthacenderivate. Granted DE3030612A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7928889 1979-08-20
GB8023715A GB2056443B (en) 1979-08-20 1980-07-21 Cyclic compounds

Publications (2)

Publication Number Publication Date
DE3030612A1 DE3030612A1 (de) 1981-03-12
DE3030612C2 true DE3030612C2 (cg-RX-API-DMAC10.html) 1990-06-21

Family

ID=26272625

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803030612 Granted DE3030612A1 (de) 1979-08-20 1980-08-13 Naphthacenderivate.

Country Status (8)

Country Link
US (1) US4302398A (cg-RX-API-DMAC10.html)
AT (1) AT367387B (cg-RX-API-DMAC10.html)
CH (1) CH646680A5 (cg-RX-API-DMAC10.html)
DE (1) DE3030612A1 (cg-RX-API-DMAC10.html)
FR (1) FR2463763A1 (cg-RX-API-DMAC10.html)
GB (1) GB2056443B (cg-RX-API-DMAC10.html)
IT (1) IT1132539B (cg-RX-API-DMAC10.html)
NL (1) NL8004716A (cg-RX-API-DMAC10.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415498A (en) * 1979-11-07 1983-11-15 Research Corporation Synthesis of daunomycinone and the derivatives thereof
US4540695A (en) * 1981-08-12 1985-09-10 Sumitomo Chemical Co., Ltd. Aminonaphthacene derivatives and their use
GB2125030B (en) * 1982-08-13 1986-11-26 Erba Farmitalia Naphthacenequinone synthesis
FR2560876B1 (fr) * 1984-03-09 1987-01-16 Hoechst Lab Nouvelles anthracyclinones, leur procede de preparation, nouveaux glycosides (anthracyclines) obtenus a partir de ces anthracyclinones, utilisation de ces glycosides en tant que medicaments
DE3712350A1 (de) * 1987-04-11 1988-10-20 Behringwerke Ag Semisynthetische rhodomycine, verfahren zu ihrer herstellung und ihre verwendung als zytostatika
DE3822220A1 (de) * 1988-07-01 1990-01-04 Behringwerke Ag Modifizierte rhodomycine, verfahren zu ihrer herstellung und ihre verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB877874A (en) * 1959-02-09 1961-09-20 American Cyanamid Co Method of producing polycyclic aromatic boron-containing compounds
US3287270A (en) * 1964-05-05 1966-11-22 Mobil Oil Corp Lubricants and fuels containing boroxarophenanthrene compounds
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
GB1527050A (en) * 1976-06-19 1978-10-04 Farmaceutici Italia Optically active anthracyclinones
US4316985A (en) * 1979-01-16 1982-02-23 Hoffmann-La Roche Inc. Cyclic compounds

Also Published As

Publication number Publication date
FR2463763B1 (cg-RX-API-DMAC10.html) 1984-03-09
NL8004716A (nl) 1981-02-24
CH646680A5 (de) 1984-12-14
GB2056443A (en) 1981-03-18
IT8024048A0 (it) 1980-08-07
DE3030612A1 (de) 1981-03-12
US4302398A (en) 1981-11-24
GB2056443B (en) 1984-01-18
FR2463763A1 (fr) 1981-02-27
AT367387B (de) 1982-06-25
ATA422580A (de) 1981-11-15
IT1132539B (it) 1986-07-02

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Legal Events

Date Code Title Description
8101 Request for examination as to novelty
8128 New person/name/address of the agent

Representative=s name: LEDERER, F., DIPL.-CHEM. DR., PAT.-ANW., 8000 MUEN

8110 Request for examination paragraph 44
8105 Search report available
D2 Grant after examination
8327 Change in the person/name/address of the patent owner

Owner name: F. HOFFMANN-LA ROCHE AG, BASEL, CH

8328 Change in the person/name/address of the agent

Free format text: LEDERER, F., DIPL.-CHEM. DR., 8000 MUENCHEN RIEDERER FRHR. VON PAAR ZU SCHOENAU, A., DIPL.-ING., PAT.-ANWAELTE, 8300 LANDSHUT

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee