DE3021792C2 - - Google Patents

Info

Publication number
DE3021792C2
DE3021792C2 DE3021792A DE3021792A DE3021792C2 DE 3021792 C2 DE3021792 C2 DE 3021792C2 DE 3021792 A DE3021792 A DE 3021792A DE 3021792 A DE3021792 A DE 3021792A DE 3021792 C2 DE3021792 C2 DE 3021792C2
Authority
DE
Germany
Prior art keywords
straight
carbon atoms
radical
chain
branched lower
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3021792A
Other languages
German (de)
English (en)
Other versions
DE3021792A1 (de
Inventor
Richard A. Schnettler
Richard C. Dage
J. Martin Cincinnati Ohio Us Grisar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3021792(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of DE3021792A1 publication Critical patent/DE3021792A1/de
Application granted granted Critical
Publication of DE3021792C2 publication Critical patent/DE3021792C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19803021792 1979-06-18 1980-06-11 Neue 4-aroylimidazol-2-one Granted DE3021792A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US11920780A 1980-02-07 1980-02-07

Publications (2)

Publication Number Publication Date
DE3021792A1 DE3021792A1 (de) 1981-01-22
DE3021792C2 true DE3021792C2 (ja) 1989-08-10

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803021792 Granted DE3021792A1 (de) 1979-06-18 1980-06-11 Neue 4-aroylimidazol-2-one

Country Status (20)

Country Link
AT (1) AT375349B (ja)
AU (1) AU532783B2 (ja)
CA (1) CA1132554A (ja)
CH (1) CH646155A5 (ja)
DE (1) DE3021792A1 (ja)
DK (1) DK160269C (ja)
ES (1) ES492255A0 (ja)
FR (1) FR2459233A1 (ja)
GB (1) GB2055364B (ja)
HK (1) HK61486A (ja)
HU (1) HU186736B (ja)
IE (1) IE50646B1 (ja)
IL (1) IL60243A (ja)
IT (1) IT1143922B (ja)
MY (1) MY8600709A (ja)
NL (2) NL193752C (ja)
NO (1) NO152841C (ja)
NZ (1) NZ193935A (ja)
PH (1) PH18683A (ja)
SE (2) SE447107B (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4329470A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
GB2097792B (en) * 1981-05-04 1985-01-03 Merrell Dow Pharma 1,3-dihydro-2h-imidazol-2-ones
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
WO2005092333A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
CA2560528A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
EP2218442A1 (en) 2005-11-09 2010-08-18 CombinatoRx, Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2328910B1 (en) 2008-06-04 2014-08-06 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA3100941C (en) 2011-03-01 2024-03-05 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
US10011637B2 (en) 2013-06-05 2018-07-03 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase C, method of making and using same
KR102456567B1 (ko) 2013-08-09 2022-10-19 알데릭스, 인코포레이티드 인산염 수송을 억제하기 위한 화합물 및 방법
EP3972599A1 (en) 2019-05-21 2022-03-30 Ardelyx, Inc. Combination for lowering serum phosphate in a patient
CN114539157B (zh) * 2022-03-03 2023-12-22 曲靖师范学院 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
CH646155A5 (de) 1984-11-15
NL300015I2 (nl) 2000-10-02
SE447107B (sv) 1986-10-27
ES8105299A1 (es) 1981-06-01
NL8003498A (nl) 1980-12-22
HK61486A (en) 1986-08-29
IE50646B1 (en) 1986-06-11
GB2055364B (en) 1983-06-08
DE3021792A1 (de) 1981-01-22
MY8600709A (en) 1986-12-31
AU5911880A (en) 1981-01-08
AU532783B2 (en) 1983-10-13
ES492255A0 (es) 1981-06-01
NZ193935A (en) 1985-05-31
SE8501452D0 (sv) 1985-03-25
DK259080A (da) 1980-12-19
NL300015I1 (nl) 2000-11-01
NO801796L (no) 1980-12-19
ATA314280A (de) 1983-12-15
DK160269C (da) 1991-07-22
IE801162L (en) 1980-12-18
SE464559B (sv) 1991-05-13
IL60243A0 (en) 1980-09-16
GB2055364A (en) 1981-03-04
NO152841B (no) 1985-08-19
FR2459233B1 (ja) 1983-09-23
DK160269B (da) 1991-02-18
IT8048997A0 (it) 1980-06-17
CA1132554A (en) 1982-09-28
PH18683A (en) 1985-08-29
FR2459233A1 (fr) 1981-01-09
IT1143922B (it) 1986-10-29
NL193752C (nl) 2000-09-04
AT375349B (de) 1984-07-25
SE8004253L (sv) 1980-12-19
SE8501452L (sv) 1985-03-25
HU186736B (en) 1985-09-30
IL60243A (en) 1987-01-30
NL193752B (nl) 2000-05-01
NO152841C (no) 1985-11-27

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition