DE2808563A1 - Derivate der 3-thio-6-(1-hydroxyaethyl)-7-oxo-1-aza-bicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en- 2-carbonsaeure, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents

Derivate der 3-thio-6-(1-hydroxyaethyl)-7-oxo-1-aza-bicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en- 2-carbonsaeure, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Info

Publication number
DE2808563A1
DE2808563A1 DE19782808563 DE2808563A DE2808563A1 DE 2808563 A1 DE2808563 A1 DE 2808563A1 DE 19782808563 DE19782808563 DE 19782808563 DE 2808563 A DE2808563 A DE 2808563A DE 2808563 A1 DE2808563 A1 DE 2808563A1
Authority
DE
Germany
Prior art keywords
formula
compound
salt
salts
fractions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782808563
Other languages
German (de)
English (en)
Inventor
Stephen John Box
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9366/77A external-priority patent/GB1601688A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of DE2808563A1 publication Critical patent/DE2808563A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19782808563 1977-03-05 1978-02-28 Derivate der 3-thio-6-(1-hydroxyaethyl)-7-oxo-1-aza-bicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en- 2-carbonsaeure, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel Withdrawn DE2808563A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9366/77A GB1601688A (en) 1977-03-05 1977-03-05 6-(1-hydroxyethyl)-7-oxo 1-aza bicyclo (3,2,0)-hept-2-ene-2-carboxylic acid derivatives and their use in pharmaceutical compositions
GB3283677 1977-08-05

Publications (1)

Publication Number Publication Date
DE2808563A1 true DE2808563A1 (de) 1978-09-07

Family

ID=26242889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782808563 Withdrawn DE2808563A1 (de) 1977-03-05 1978-02-28 Derivate der 3-thio-6-(1-hydroxyaethyl)-7-oxo-1-aza-bicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en- 2-carbonsaeure, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Country Status (11)

Country Link
JP (1) JPS53116396A (es)
AU (1) AU525142B2 (es)
CH (1) CH641805A5 (es)
DE (1) DE2808563A1 (es)
DK (1) DK98478A (es)
ES (1) ES467562A1 (es)
FR (1) FR2401162A1 (es)
IE (1) IE46736B1 (es)
IT (1) IT7848280A0 (es)
NL (1) NL7802356A (es)
SE (1) SE7802462L (es)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2816608A1 (de) * 1977-04-18 1978-10-19 Merck & Co Inc Antibiotisches n-acetyl-dehydro- thienamycin
EP0008885A1 (en) * 1978-09-09 1980-03-19 Beecham Group Plc Beta-lactam compounds, their preparation and use
EP0033209B1 (en) * 1980-01-25 1984-06-13 Beecham Group Plc Beta-lactam containing compounds, their preparation and use

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN155384B (es) * 1980-05-14 1985-01-19 Pfizer
JP4977670B2 (ja) * 2008-09-11 2012-07-18 啓司 関口 生花整形器

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK143713C (da) * 1975-11-21 1982-03-08 Merck & Co Inc Fremgangsmaade til fremstilling af et antibiotisk stof n-acetyl-thienamycin og salte deraf
DK143712C (da) * 1975-11-21 1982-03-22 Merck & Co Inc Fremgangsmaade til fremstilling af de antibiotiske stoffer 890a1 og 890a3
NL7704040A (nl) * 1976-04-28 1977-11-01 Merck & Co Inc Werkwijze voor het bereiden van nieuwe anti- biotica.

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2816608A1 (de) * 1977-04-18 1978-10-19 Merck & Co Inc Antibiotisches n-acetyl-dehydro- thienamycin
EP0008885A1 (en) * 1978-09-09 1980-03-19 Beecham Group Plc Beta-lactam compounds, their preparation and use
EP0033209B1 (en) * 1980-01-25 1984-06-13 Beecham Group Plc Beta-lactam containing compounds, their preparation and use

Also Published As

Publication number Publication date
FR2401162A1 (fr) 1979-03-23
IT7848280A0 (it) 1978-03-03
SE7802462L (sv) 1978-09-06
JPS53116396A (en) 1978-10-11
AU525142B2 (en) 1982-10-21
AU3384178A (en) 1979-09-06
IE46736B1 (en) 1983-09-07
ES467562A1 (es) 1980-05-16
DK98478A (da) 1978-09-06
CH641805A5 (en) 1984-03-15
IE780443L (en) 1978-09-05
FR2401162B1 (es) 1980-08-29
NL7802356A (nl) 1978-09-07

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: JUNG, E., DIPL.-CHEM. DR.PHIL. SCHIRDEWAHN, J., DI

8141 Disposal/no request for examination