DE2638024C2 - Verfahren zur Erhöhung der Cephamycin C-Ausbeute beim Züchten eines Cephamycin C erzeugenden Stammes der Gattung Streptomyces - Google Patents

Verfahren zur Erhöhung der Cephamycin C-Ausbeute beim Züchten eines Cephamycin C erzeugenden Stammes der Gattung Streptomyces

Info

Publication number
DE2638024C2
DE2638024C2 DE2638024A DE2638024A DE2638024C2 DE 2638024 C2 DE2638024 C2 DE 2638024C2 DE 2638024 A DE2638024 A DE 2638024A DE 2638024 A DE2638024 A DE 2638024A DE 2638024 C2 DE2638024 C2 DE 2638024C2
Authority
DE
Germany
Prior art keywords
medium
cephamycin
sterile
expressed
hcl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2638024A
Other languages
German (de)
English (en)
Other versions
DE2638024A1 (de
Inventor
Jerome Morganville N.J. Birnbaum
Edward Rahway N.J. Inamine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2638024A1 publication Critical patent/DE2638024A1/de
Application granted granted Critical
Publication of DE2638024C2 publication Critical patent/DE2638024C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
DE2638024A 1975-11-21 1976-08-24 Verfahren zur Erhöhung der Cephamycin C-Ausbeute beim Züchten eines Cephamycin C erzeugenden Stammes der Gattung Streptomyces Expired DE2638024C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/634,106 US3977942A (en) 1975-11-21 1975-11-21 Fermentation of cephamycin C

Publications (2)

Publication Number Publication Date
DE2638024A1 DE2638024A1 (de) 1977-05-26
DE2638024C2 true DE2638024C2 (de) 1985-05-02

Family

ID=24542463

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2638024A Expired DE2638024C2 (de) 1975-11-21 1976-08-24 Verfahren zur Erhöhung der Cephamycin C-Ausbeute beim Züchten eines Cephamycin C erzeugenden Stammes der Gattung Streptomyces

Country Status (8)

Country Link
US (1) US3977942A (enExample)
JP (1) JPS5910200B2 (enExample)
AU (1) AU517298B2 (enExample)
CA (1) CA1064419A (enExample)
DE (1) DE2638024C2 (enExample)
ES (1) ES451318A1 (enExample)
FR (1) FR2332323A1 (enExample)
GB (1) GB1515809A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230562A (en) * 1976-09-01 1980-10-28 Snamprogetti S.P.A. Method for depolluting fresh water and salt water bodies from crude oil, petroleum products and their derivatives
JPS54119094A (en) * 1978-03-07 1979-09-14 Shionogi & Co Ltd Novel process for preparing antibiotic substance
JPS57194791A (en) * 1981-05-22 1982-11-30 Chugai Pharmaceut Co Ltd Preparation of cephamycin c

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769169A (en) * 1971-05-20 1973-10-30 Merck & Co Inc Fermentation process
US3770590A (en) * 1971-12-01 1973-11-06 Merck & Co Inc Fermentation process
JPS5318595B2 (enExample) * 1972-08-31 1978-06-15
JPS5233667B2 (enExample) * 1973-05-22 1977-08-30
US3914158A (en) * 1973-06-06 1975-10-21 Merck & Co Inc Antibiotic production
US3886044A (en) * 1974-04-25 1975-05-27 Merck & Co Inc Process of making cephamycin C by fermentation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
DE2638024A1 (de) 1977-05-26
AU517298B2 (en) 1981-07-23
GB1515809A (en) 1978-06-28
JPS5910200B2 (ja) 1984-03-07
FR2332323B1 (enExample) 1980-11-07
AU1687576A (en) 1978-02-23
ES451318A1 (es) 1978-03-01
JPS5264490A (en) 1977-05-27
FR2332323A1 (fr) 1977-06-17
US3977942A (en) 1976-08-31
CA1064419A (en) 1979-10-16

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee