DE2539941C2 - Basische Benzyloxyalkyl-Derivate, deren Herstellung und diese Verbindungen enthaltende Arzneimittel - Google Patents

Basische Benzyloxyalkyl-Derivate, deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Info

Publication number
DE2539941C2
DE2539941C2 DE2539941A DE2539941A DE2539941C2 DE 2539941 C2 DE2539941 C2 DE 2539941C2 DE 2539941 A DE2539941 A DE 2539941A DE 2539941 A DE2539941 A DE 2539941A DE 2539941 C2 DE2539941 C2 DE 2539941C2
Authority
DE
Germany
Prior art keywords
compounds
general formula
basic
preparation
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2539941A
Other languages
German (de)
English (en)
Other versions
DE2539941A1 (de
Inventor
Manfred Franz Reinhold Dr.med.vet. 7811 St Peter Herrmann
Gerhard Dipl.-Chem. Dr.Rer.Nat. 7809 Denzlingen Satzinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Goedecke GmbH
Original Assignee
Goedecke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke GmbH filed Critical Goedecke GmbH
Priority to DE2539941A priority Critical patent/DE2539941C2/de
Priority to IE1746/76A priority patent/IE43284B1/en
Priority to ES451158A priority patent/ES451158A1/es
Priority to AU17361/76A priority patent/AU502573B2/en
Priority to GB36375/76A priority patent/GB1488646A/en
Priority to SE7609746A priority patent/SE430056B/xx
Priority to LU75735A priority patent/LU75735A1/xx
Priority to FR7626768A priority patent/FR2323377A1/fr
Priority to JP51105887A priority patent/JPS5233639A/ja
Priority to BE6045664A priority patent/BE845964A/xx
Priority to DK403576A priority patent/DK153142C/da
Priority to AT668876A priority patent/AT346306B/de
Priority to NLAANVRAGE7610040,A priority patent/NL186238C/xx
Priority to CH1146076A priority patent/CH628613A5/de
Publication of DE2539941A1 publication Critical patent/DE2539941A1/de
Application granted granted Critical
Publication of DE2539941C2 publication Critical patent/DE2539941C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE2539941A 1975-09-09 1975-09-09 Basische Benzyloxyalkyl-Derivate, deren Herstellung und diese Verbindungen enthaltende Arzneimittel Expired DE2539941C2 (de)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DE2539941A DE2539941C2 (de) 1975-09-09 1975-09-09 Basische Benzyloxyalkyl-Derivate, deren Herstellung und diese Verbindungen enthaltende Arzneimittel
IE1746/76A IE43284B1 (en) 1975-09-09 1976-08-06 Benzyloxyalkyl derivatives
ES451158A ES451158A1 (es) 1975-09-09 1976-09-01 Procedimiento de preparacion de derivados benciloxialquili- cos.
AU17361/76A AU502573B2 (en) 1975-09-09 1976-09-01 Basic benzyloxyalkyl derivatives
GB36375/76A GB1488646A (en) 1975-09-09 1976-09-02 Benzyloxyalkyl derivatives
SE7609746A SE430056B (sv) 1975-09-09 1976-09-03 Forfarande for framstellning av nya basiska bensyloxialkylderivat
LU75735A LU75735A1 (en, 2012) 1975-09-09 1976-09-06
FR7626768A FR2323377A1 (fr) 1975-09-09 1976-09-06 Derives benzyloxyalkyles
JP51105887A JPS5233639A (en) 1975-09-09 1976-09-06 Benzyloxy alkyl derivatives and process for preparation thereof
BE6045664A BE845964A (fr) 1975-09-09 1976-09-08 Derives benzyloxyalkyles
DK403576A DK153142C (da) 1975-09-09 1976-09-08 Analogifremgangsmaade til fremstilling af o-aminoalkoxy-substituerede dibenzylethere eller farmakologisk acceptable salte deraf
AT668876A AT346306B (de) 1975-09-09 1976-09-09 Verfahren zur herstellung neuer basischer aether
NLAANVRAGE7610040,A NL186238C (nl) 1975-09-09 1976-09-09 Werkwijze ter bereiding van een geneesmiddel met pijnstillende en ontstekingswerende werking, op basis van 2-aminoalkoxydibenzyletherderivaten, alsmede werkwijze voor de bereiding van voor gebruik hiervoor geschikte 2-aminoalkoxydibenzyletherderivaten.
CH1146076A CH628613A5 (en) 1975-09-09 1976-09-09 Process for the preparation of aminoalkoxyphenylalkyl benzyl ethers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2539941A DE2539941C2 (de) 1975-09-09 1975-09-09 Basische Benzyloxyalkyl-Derivate, deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
DE2539941A1 DE2539941A1 (de) 1977-03-17
DE2539941C2 true DE2539941C2 (de) 1984-04-26

Family

ID=5955902

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2539941A Expired DE2539941C2 (de) 1975-09-09 1975-09-09 Basische Benzyloxyalkyl-Derivate, deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Country Status (14)

Country Link
JP (1) JPS5233639A (en, 2012)
AT (1) AT346306B (en, 2012)
AU (1) AU502573B2 (en, 2012)
BE (1) BE845964A (en, 2012)
CH (1) CH628613A5 (en, 2012)
DE (1) DE2539941C2 (en, 2012)
DK (1) DK153142C (en, 2012)
ES (1) ES451158A1 (en, 2012)
FR (1) FR2323377A1 (en, 2012)
GB (1) GB1488646A (en, 2012)
IE (1) IE43284B1 (en, 2012)
LU (1) LU75735A1 (en, 2012)
NL (1) NL186238C (en, 2012)
SE (1) SE430056B (en, 2012)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK368687A (da) * 1986-11-21 1988-05-22 Cheminova As Aminoalkylerede hydroxyforbindelser og deres anvendelse som fungicider
JPH032229U (en, 2012) * 1989-05-26 1991-01-10

Also Published As

Publication number Publication date
JPS6121940B2 (en, 2012) 1986-05-29
FR2323377B1 (en, 2012) 1978-11-17
ES451158A1 (es) 1977-12-01
AU502573B2 (en) 1979-08-02
IE43284B1 (en) 1981-01-28
NL186238B (nl) 1990-05-16
SE7609746L (sv) 1977-03-10
DK153142B (da) 1988-06-20
NL7610040A (en) 1977-03-11
DK403576A (da) 1977-03-10
AT346306B (de) 1978-11-10
FR2323377A1 (fr) 1977-04-08
BE845964A (fr) 1977-03-08
DE2539941A1 (de) 1977-03-17
LU75735A1 (en, 2012) 1977-06-15
NL186238C (nl) 1990-10-16
GB1488646A (en) 1977-10-12
ATA668876A (de) 1978-03-15
CH628613A5 (en) 1982-03-15
DK153142C (da) 1988-11-07
AU1736176A (en) 1978-03-09
IE43284L (en) 1977-03-09
SE430056B (sv) 1983-10-17
JPS5233639A (en) 1977-03-14

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8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee