DE69102309T2 - N-cycloalkyl-Alkylamine, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und Zwischenprodukte zu ihrer Synthese. - Google Patents

N-cycloalkyl-Alkylamine, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und Zwischenprodukte zu ihrer Synthese.

Info

Publication number
DE69102309T2
DE69102309T2 DE69102309T DE69102309T DE69102309T2 DE 69102309 T2 DE69102309 T2 DE 69102309T2 DE 69102309 T DE69102309 T DE 69102309T DE 69102309 T DE69102309 T DE 69102309T DE 69102309 T2 DE69102309 T2 DE 69102309T2
Authority
DE
Germany
Prior art keywords
cycloalkyl
alkylamines
medicaments
intermediates
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69102309T
Other languages
English (en)
Other versions
DE69102309D1 (de
Inventor
Gilbert Aubard
Alain Calvet
Jean-Pierre Defaux
Claude-Jean Gouret
Agnes Grouhel
James Hudspeth
Henri Jacobelli
Jean-Louis Junien
Xavier Pascaud
Francois Roman
Lin Yuan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jouveinal SA
Original Assignee
Jouveinal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/484,403 external-priority patent/US5034419A/en
Priority claimed from FR9002494A external-priority patent/FR2658822A1/fr
Application filed by Jouveinal SA filed Critical Jouveinal SA
Application granted granted Critical
Publication of DE69102309D1 publication Critical patent/DE69102309D1/de
Publication of DE69102309T2 publication Critical patent/DE69102309T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69102309T 1990-02-26 1991-02-25 N-cycloalkyl-Alkylamine, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und Zwischenprodukte zu ihrer Synthese. Expired - Fee Related DE69102309T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/484,403 US5034419A (en) 1988-09-01 1990-02-26 N-cycloalkylalkylamines, process for their preparation, their use as medicament and their synthesis intermediates
FR9002494A FR2658822A1 (fr) 1990-02-28 1990-02-28 N-cycloalkylalkylamines, leur procede de preparation, leur utilisation comme medicament et leurs intermediaires de synthese.

Publications (2)

Publication Number Publication Date
DE69102309D1 DE69102309D1 (de) 1994-07-14
DE69102309T2 true DE69102309T2 (de) 1994-09-15

Family

ID=26227891

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69102309T Expired - Fee Related DE69102309T2 (de) 1990-02-26 1991-02-25 N-cycloalkyl-Alkylamine, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel und Zwischenprodukte zu ihrer Synthese.

Country Status (14)

Country Link
EP (1) EP0445013B1 (de)
JP (1) JP2899429B2 (de)
AT (1) ATE106879T1 (de)
AU (1) AU633695B2 (de)
CA (1) CA2037114C (de)
DE (1) DE69102309T2 (de)
DK (1) DK0445013T3 (de)
ES (1) ES2054452T3 (de)
FI (1) FI97384C (de)
HU (1) HU215430B (de)
IE (1) IE66180B1 (de)
IL (1) IL97354A (de)
NZ (1) NZ237224A (de)
PT (1) PT96885B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849760A (en) * 1993-12-09 1998-12-15 Institut De Recherche Jouveinal 2-(arylalkenyl)azacycloalkane derivatives as ligands for sigma receptors
GB9405392D0 (en) * 1994-03-18 1994-05-04 Secr Defence Microorganism detection apparatus and method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS584748A (ja) * 1981-06-30 1983-01-11 Takasago Corp エナミンまたはイミンの製造方法
IL86740A (en) * 1987-06-30 1992-11-15 Tanabe Seiyaku Co Thiphene derivatives,their preparation and pharmaceutical compositions containing them
JPS6416778A (en) * 1987-07-09 1989-01-20 Tanabe Seiyaku Co Thiophene derivative

Also Published As

Publication number Publication date
FI97384B (fi) 1996-08-30
AU633695B2 (en) 1993-02-04
FI97384C (fi) 1996-12-10
IL97354A (en) 1995-12-08
ATE106879T1 (de) 1994-06-15
IL97354A0 (en) 1992-05-25
IE910620A1 (en) 1991-08-28
JP2899429B2 (ja) 1999-06-02
EP0445013A1 (de) 1991-09-04
AU7134091A (en) 1991-08-29
FI910894A0 (fi) 1991-02-25
PT96885B (pt) 1998-07-31
PT96885A (pt) 1991-10-31
HUT62284A (en) 1993-04-28
IE66180B1 (en) 1995-12-13
NZ237224A (en) 1992-05-26
FI910894A (fi) 1991-08-27
DE69102309D1 (de) 1994-07-14
HU910625D0 (en) 1991-09-30
ES2054452T3 (es) 1994-08-01
EP0445013B1 (de) 1994-06-08
JPH0616598A (ja) 1994-01-25
HU215430B (hu) 1999-09-28
CA2037114C (en) 2003-09-09
CA2037114A1 (en) 1991-08-27
DK0445013T3 (da) 1994-07-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee