GB1488646A - Benzyloxyalkyl derivatives - Google Patents

Benzyloxyalkyl derivatives

Info

Publication number
GB1488646A
GB1488646A GB36375/76A GB3637576A GB1488646A GB 1488646 A GB1488646 A GB 1488646A GB 36375/76 A GB36375/76 A GB 36375/76A GB 3637576 A GB3637576 A GB 3637576A GB 1488646 A GB1488646 A GB 1488646A
Authority
GB
United Kingdom
Prior art keywords
formula
benzyloxyalkyl
derivatives
benzyloxyalkyl derivatives
aminoalkoxyphenylalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB36375/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of GB1488646A publication Critical patent/GB1488646A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted

Abstract

Aminoalkoxyphenylalkyl benzyl ethers of the formula I are prepared by reacting a compound of the formula II with one of the formula III. The symbols in the formulae have the meaning stated in Claim 1. The compounds of the formula I and their pharmacologically compatible salts display lower toxicity, and pronounced antiinflammatory and good analgesic effects. <IMAGE>
GB36375/76A 1975-09-09 1976-09-02 Benzyloxyalkyl derivatives Expired GB1488646A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2539941A DE2539941C2 (en) 1975-09-09 1975-09-09 Basic benzyloxyalkyl derivatives, their preparation and pharmaceuticals containing these compounds

Publications (1)

Publication Number Publication Date
GB1488646A true GB1488646A (en) 1977-10-12

Family

ID=5955902

Family Applications (1)

Application Number Title Priority Date Filing Date
GB36375/76A Expired GB1488646A (en) 1975-09-09 1976-09-02 Benzyloxyalkyl derivatives

Country Status (14)

Country Link
JP (1) JPS5233639A (en)
AT (1) AT346306B (en)
AU (1) AU502573B2 (en)
BE (1) BE845964A (en)
CH (1) CH628613A5 (en)
DE (1) DE2539941C2 (en)
DK (1) DK153142C (en)
ES (1) ES451158A1 (en)
FR (1) FR2323377A1 (en)
GB (1) GB1488646A (en)
IE (1) IE43284B1 (en)
LU (1) LU75735A1 (en)
NL (1) NL186238C (en)
SE (1) SE430056B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0269363A2 (en) * 1986-11-21 1988-06-01 A/S Cheminova Amino-alkylated hydroxy compounds and their use as fungicides

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH032229U (en) * 1989-05-26 1991-01-10

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0269363A2 (en) * 1986-11-21 1988-06-01 A/S Cheminova Amino-alkylated hydroxy compounds and their use as fungicides
EP0269363A3 (en) * 1986-11-21 1989-11-23 A/S Cheminova Amino-alkylated hydroxy compounds and their use as fungicides

Also Published As

Publication number Publication date
ATA668876A (en) 1978-03-15
NL186238C (en) 1990-10-16
CH628613A5 (en) 1982-03-15
SE7609746L (en) 1977-03-10
JPS5233639A (en) 1977-03-14
JPS6121940B2 (en) 1986-05-29
BE845964A (en) 1977-03-08
NL7610040A (en) 1977-03-11
IE43284L (en) 1977-03-09
ES451158A1 (en) 1977-12-01
NL186238B (en) 1990-05-16
LU75735A1 (en) 1977-06-15
FR2323377A1 (en) 1977-04-08
DK403576A (en) 1977-03-10
AU502573B2 (en) 1979-08-02
DE2539941A1 (en) 1977-03-17
SE430056B (en) 1983-10-17
FR2323377B1 (en) 1978-11-17
DE2539941C2 (en) 1984-04-26
AU1736176A (en) 1978-03-09
DK153142C (en) 1988-11-07
DK153142B (en) 1988-06-20
AT346306B (en) 1978-11-10
IE43284B1 (en) 1981-01-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee