ES8103057A1 - Heterocyclic compound - Google Patents

Heterocyclic compound

Info

Publication number
ES8103057A1
ES8103057A1 ES489883A ES489883A ES8103057A1 ES 8103057 A1 ES8103057 A1 ES 8103057A1 ES 489883 A ES489883 A ES 489883A ES 489883 A ES489883 A ES 489883A ES 8103057 A1 ES8103057 A1 ES 8103057A1
Authority
ES
Spain
Prior art keywords
formula
heterocyclic compound
compounds
symbols
prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES489883A
Other languages
Spanish (es)
Other versions
ES489883A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES8103057A1 publication Critical patent/ES8103057A1/en
Publication of ES489883A0 publication Critical patent/ES489883A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin

Abstract

Hydantoin derivatives of the formula I < IMAGE > are prepared by the processes mentioned in Claims 1, 12, 16, 18, 25 and 27. The symbols in the formula I have the meaning indicated in Claim 1. The compounds of the formula I have pharmacological properties which are related to those of the natural prostaglandins.
ES489883A 1976-06-03 1980-03-25 A METHOD OF PREPARING HETERO-CYCLIC COMPOUNDS DERIVED FROM HYDANTOIN Granted ES489883A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2287776 1976-06-03
GB5034076 1976-12-02
GB1214577 1977-03-23

Publications (2)

Publication Number Publication Date
ES8103057A1 true ES8103057A1 (en) 1981-02-16
ES489883A0 ES489883A0 (en) 1981-02-16

Family

ID=27256793

Family Applications (5)

Application Number Title Priority Date Filing Date
ES459412A Expired ES459412A1 (en) 1976-06-03 1977-06-02 Heterocyclic compound
ES470428A Expired ES470428A1 (en) 1976-06-03 1978-06-01 Heterocyclic compound
ES478156A Expired ES478156A1 (en) 1976-06-03 1979-02-28 Heterocyclic compound
ES482010A Expired ES482010A1 (en) 1976-06-03 1979-06-28 Heterocyclic compound
ES489883A Granted ES489883A0 (en) 1976-06-03 1980-03-25 A METHOD OF PREPARING HETERO-CYCLIC COMPOUNDS DERIVED FROM HYDANTOIN

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES459412A Expired ES459412A1 (en) 1976-06-03 1977-06-02 Heterocyclic compound
ES470428A Expired ES470428A1 (en) 1976-06-03 1978-06-01 Heterocyclic compound
ES478156A Expired ES478156A1 (en) 1976-06-03 1979-02-28 Heterocyclic compound
ES482010A Expired ES482010A1 (en) 1976-06-03 1979-06-28 Heterocyclic compound

Country Status (12)

Country Link
JP (1) JPS52151168A (en)
CA (1) CA1176261A (en)
CH (3) CH645631A5 (en)
DE (1) DE2724948A1 (en)
DK (1) DK244577A (en)
ES (5) ES459412A1 (en)
FI (1) FI71930C (en)
FR (1) FR2362839A1 (en)
HU (1) HU183046B (en)
NL (1) NL7706064A (en)
NZ (1) NZ184281A (en)
SE (2) SE446336B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602188A (en) * 1977-12-01 1981-11-11 Wellcome Found Hydantoin derivatives
AU527959B2 (en) * 1977-09-05 1983-03-31 Wellcome Foundation Limited, The Hydantoin derivatives
AU531493B2 (en) * 1977-12-01 1983-08-25 The Wellcome Foundation Limited Thiohydantion derivatives
DE2963795D1 (en) * 1978-01-23 1982-11-11 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (en) * 1978-03-30 1979-10-17 Beecham Group Plc Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them
GB1599740A (en) * 1978-05-31 1981-10-07 Wellcome Found Hydantoin derivatives
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
AU4806979A (en) * 1978-06-15 1979-12-20 Beecham Group Limited 1,2,4 triazole derivatives
EP0006352A1 (en) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them
IL59065A0 (en) * 1979-01-18 1980-05-30 Beecham Group Ltd Hydantoin derivatives,their preparation pharmaceutical compositons containing them
JPS55151569A (en) * 1979-05-09 1980-11-26 Wellcome Found Optically active heterocyclic compounds* their synthesis and medical blend containing them
US4684735A (en) * 1985-07-01 1987-08-04 Stauffer Chemical Company Promotion of raney nickel hydrogenation catalyst
JP3022878U (en) * 1995-08-18 1996-04-02 有限会社春江加工 Case for mini discs
EP1453811A2 (en) 2001-11-30 2004-09-08 Eli Lilly And Company Peroxisome proliferator activated receptor agonists
US7179820B2 (en) * 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
BRPI0411057A (en) * 2003-06-06 2006-07-25 Allergan Inc prostaglandin and piperidinyl analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524818A (en) * 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Also Published As

Publication number Publication date
DK244577A (en) 1977-12-04
ES478156A1 (en) 1979-11-01
NL7706064A (en) 1977-12-06
CH646426A5 (en) 1984-11-30
CA1176261A (en) 1984-10-16
FR2362839B1 (en) 1980-02-01
SE8203161L (en) 1982-05-19
FI71930C (en) 1987-03-09
DE2724948A1 (en) 1977-12-15
CH645631A5 (en) 1984-10-15
ES470428A1 (en) 1979-09-01
ES459412A1 (en) 1978-11-01
JPS6222986B2 (en) 1987-05-20
SE446336B (en) 1986-09-01
ES482010A1 (en) 1980-08-16
NZ184281A (en) 1980-04-28
SE7706428L (en) 1977-12-04
FI771763A (en) 1977-12-04
FI71930B (en) 1986-11-28
ES489883A0 (en) 1981-02-16
FR2362839A1 (en) 1978-03-24
CH647511A5 (en) 1985-01-31
HU183046B (en) 1984-04-28
JPS52151168A (en) 1977-12-15

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