ES8400411A1 - Novel sulfimine compound - Google Patents

Novel sulfimine compound

Info

Publication number
ES8400411A1
ES8400411A1 ES518827A ES518827A ES8400411A1 ES 8400411 A1 ES8400411 A1 ES 8400411A1 ES 518827 A ES518827 A ES 518827A ES 518827 A ES518827 A ES 518827A ES 8400411 A1 ES8400411 A1 ES 8400411A1
Authority
ES
Spain
Prior art keywords
novel
sulfimine compound
general formula
compounds
sulfimine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518827A
Other languages
Spanish (es)
Other versions
ES518827A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES8400411A1 publication Critical patent/ES8400411A1/en
Publication of ES518827A0 publication Critical patent/ES518827A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Novel sulphoximides of the general formula < IMAGE > in which A, B, R1 and R2 are defined as in Patent Claim 1, which exhibit useful pharmacological properties, in particular antithrombotic effects. The compounds of the general formula I can be prepared by processes which are customary for analogous compounds.
ES518827A 1981-07-25 1983-01-07 PROCEDURE FOR THE PREPARATION OF NEW SULFIMINES. Granted ES518827A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813129444 DE3129444A1 (en) 1981-07-25 1981-07-25 Sulphoximides, their preparation, and medicaments containing these compounds

Publications (2)

Publication Number Publication Date
ES8400411A1 true ES8400411A1 (en) 1983-10-16
ES518827A0 ES518827A0 (en) 1983-10-16

Family

ID=6137766

Family Applications (4)

Application Number Title Priority Date Filing Date
ES514275A Expired ES8305333A1 (en) 1981-07-25 1982-07-23 Novel sulfimine compound
ES518828A Expired ES8400412A1 (en) 1981-07-25 1983-01-07 Novel sulfimine compound
ES518827A Granted ES518827A0 (en) 1981-07-25 1983-01-07 PROCEDURE FOR THE PREPARATION OF NEW SULFIMINES.
ES518826A Granted ES518826A0 (en) 1981-07-25 1983-01-07 PROCEDURE FOR THE PREPARATION OF NEW SULFIMINES.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES514275A Expired ES8305333A1 (en) 1981-07-25 1982-07-23 Novel sulfimine compound
ES518828A Expired ES8400412A1 (en) 1981-07-25 1983-01-07 Novel sulfimine compound

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES518826A Granted ES518826A0 (en) 1981-07-25 1983-01-07 PROCEDURE FOR THE PREPARATION OF NEW SULFIMINES.

Country Status (19)

Country Link
JP (1) JPS5824559A (en)
KR (1) KR840000491A (en)
AR (1) AR230745A1 (en)
AU (1) AU556082B2 (en)
CA (1) CA1175430A (en)
CS (1) CS236488B2 (en)
DD (1) DD202871A5 (en)
DE (2) DE3129444A1 (en)
DK (1) DK329582A (en)
ES (4) ES8305333A1 (en)
FI (1) FI822550L (en)
GR (1) GR76181B (en)
HU (1) HU188188B (en)
NO (1) NO822255L (en)
PL (1) PL137725B1 (en)
PT (1) PT75297A (en)
SU (1) SU1158041A3 (en)
YU (1) YU158182A (en)
ZA (1) ZA825273B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2247579B1 (en) * 2008-01-17 2012-04-18 Bayer Pharma Aktiengesellschaft Sulphoximine-substituted quinazoline derivatives as immunomodulators, their preparation and use as medicaments

Also Published As

Publication number Publication date
AU8637882A (en) 1983-04-14
FI822550L (en) 1983-01-26
DE3246980A1 (en) 1984-06-20
DD202871A5 (en) 1983-10-05
CA1175430A (en) 1984-10-02
DE3129444A1 (en) 1983-02-10
NO822255L (en) 1983-01-26
SU1158041A3 (en) 1985-05-23
PT75297A (en) 1982-08-01
AR230745A1 (en) 1984-06-29
JPS5824559A (en) 1983-02-14
FI822550A0 (en) 1982-07-20
ES8400410A1 (en) 1983-10-16
ES518828A0 (en) 1983-10-16
HU188188B (en) 1986-03-28
ES514275A0 (en) 1983-04-01
ZA825273B (en) 1984-03-28
PL137725B1 (en) 1986-07-31
YU158182A (en) 1984-08-31
AU556082B2 (en) 1986-10-23
ES518827A0 (en) 1983-10-16
ES8400412A1 (en) 1983-10-16
ES518826A0 (en) 1983-10-16
GR76181B (en) 1984-08-03
PL237600A1 (en) 1983-03-28
DK329582A (en) 1983-01-26
ES8305333A1 (en) 1983-04-01
KR840000491A (en) 1984-02-22
CS236488B2 (en) 1985-05-15

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