DE19616486C5 - Verfahren zur Senkung des Blutglukosespiegels in Säugern - Google Patents

Verfahren zur Senkung des Blutglukosespiegels in Säugern Download PDF

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Publication number
DE19616486C5
DE19616486C5 DE19616486.9A DE19616486A DE19616486C5 DE 19616486 C5 DE19616486 C5 DE 19616486C5 DE 19616486 A DE19616486 A DE 19616486A DE 19616486 C5 DE19616486 C5 DE 19616486C5
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DE
Germany
Prior art keywords
glp
inhibitors
inhibitor
lowering
blood glucose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE19616486.9A
Other languages
German (de)
English (en)
Other versions
DE19616486A1 (de
DE19616486C2 (de
Inventor
Dr. Demuth Hans-Ulrich
Dr. Rosche Fred
Dipl.-Chem. Schmidt Jörn
Robert P. Pauly
Prof. Dr. Mclntosh Christopher H.S.
Prof. Dr. Pederson Ray A.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Royalty Pharma Collection Trust
Original Assignee
Royalty Pharma Collection Trust
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Royalty Pharma Collection Trust filed Critical Royalty Pharma Collection Trust
Priority to DE122010000020C priority Critical patent/DE122010000020I1/de
Priority to DE19616486.9A priority patent/DE19616486C5/de
Priority to EP00119496.8A priority patent/EP1084705B1/de
Priority to AT97924866T priority patent/ATE202705T1/de
Priority to AU30233/97A priority patent/AU721477C/en
Priority to HK99104351.7A priority patent/HK1019204B/xx
Priority to US09/155,833 priority patent/US6303661B1/en
Priority to DK00119496.8T priority patent/DK1084705T3/da
Priority to NZ332707A priority patent/NZ332707A/xx
Priority to DE122007000083C priority patent/DE122007000083I1/de
Priority to KR1020107003160A priority patent/KR20100036363A/ko
Priority to KR1020057019835A priority patent/KR20050104428A/ko
Priority to KR1019980707018A priority patent/KR100617676B1/ko
Priority to CN97194017A priority patent/CN1132578C/zh
Priority to DK97924866T priority patent/DK0896538T3/da
Priority to CA002252576A priority patent/CA2252576C/en
Priority to EP97924866A priority patent/EP0896538B1/de
Priority to DE59703959T priority patent/DE59703959D1/de
Priority to SI9730802T priority patent/SI1084705T1/sl
Priority to PT97924866T priority patent/PT896538E/pt
Priority to EP10184503.0A priority patent/EP2289513A3/de
Priority to PT119496T priority patent/PT1084705E/pt
Priority to KR1020077015000A priority patent/KR100950722B1/ko
Priority to CNB2003101131191A priority patent/CN1269528C/zh
Priority to KR1020117031497A priority patent/KR20120014064A/ko
Priority to PCT/DE1997/000820 priority patent/WO1997040832A1/de
Priority to RU98121213/14A priority patent/RU2189233C2/ru
Priority to JP53845397A priority patent/JP2001510442A/ja
Priority to ES00119496.8T priority patent/ES2505665T3/es
Priority to ES97924866T priority patent/ES2158562T3/es
Priority to DE200712000038 priority patent/DE122007000038I1/de
Publication of DE19616486A1 publication Critical patent/DE19616486A1/de
Application granted granted Critical
Publication of DE19616486C2 publication Critical patent/DE19616486C2/de
Priority to HK01103193.8A priority patent/HK1033420B/xx
Priority to GR20010401649T priority patent/GR3036788T3/el
Priority to US11/022,087 priority patent/US20050107309A1/en
Priority to LU91334C priority patent/LU91334I2/fr
Priority to NL300280C priority patent/NL300280I2/nl
Priority to NL300308C priority patent/NL300308I2/nl
Priority to LU91382C priority patent/LU91382I2/fr
Priority to JP2008320714A priority patent/JP2009137973A/ja
Priority to JP2011284809A priority patent/JP2012092136A/ja
Priority to US13/458,484 priority patent/US20130116290A1/en
Priority to LTPA2014045C priority patent/LTPA2014045I1/lt
Priority to LTPA2014044C priority patent/LTPA2014044I1/lt
Priority to LTPA2014043C priority patent/LTPA2014043I1/lt
Priority to LU92612C priority patent/LU92612I2/xx
Priority to LU92614C priority patent/LU92614I2/xx
Priority to LU92613C priority patent/LU92613I2/xx
Priority to LU92615C priority patent/LU92615I2/xx
Priority to LU92611C priority patent/LU92611I2/xx
Priority to FR14C0089C priority patent/FR14C0089I1/fr
Priority to US15/042,892 priority patent/US20170007582A1/en
Anticipated expiration legal-status Critical
Publication of DE19616486C5 publication Critical patent/DE19616486C5/de
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
DE19616486.9A 1996-04-25 1996-04-25 Verfahren zur Senkung des Blutglukosespiegels in Säugern Expired - Lifetime DE19616486C5 (de)

Priority Applications (51)

Application Number Priority Date Filing Date Title
DE122010000020C DE122010000020I1 (de) 1996-04-25 1996-04-25 Verfahren zur Senkung des Blutglukosespiegels in Säugern
DE19616486.9A DE19616486C5 (de) 1996-04-25 1996-04-25 Verfahren zur Senkung des Blutglukosespiegels in Säugern
EP00119496.8A EP1084705B1 (de) 1996-04-25 1997-04-24 Verfahren zur Senkung des Blutglukosespiegels in Säugern
AT97924866T ATE202705T1 (de) 1996-04-25 1997-04-24 Verwendung von aktivitätsmindernden effektoren der dipeptidyl peptidase iv zur senkung des blutglukosespiegels in säugern
AU30233/97A AU721477C (en) 1996-04-25 1997-04-24 The use of dipeptidyl peptidase IV effectors for lowering blood glucose levels in mammals
HK99104351.7A HK1019204B (en) 1996-04-25 1997-04-24 Use of dipeptidyl peptidase iv inhibitors for lowering the blood glucose level in mammals
US09/155,833 US6303661B1 (en) 1996-04-25 1997-04-24 Use of dipeptidyl peptidase IV effectors for lowering the blood glucose level in mammals
DK00119496.8T DK1084705T3 (da) 1996-04-25 1997-04-24 Fremgangsmåde til sænkning af blodglucoseniveauer i pattedyr
NZ332707A NZ332707A (en) 1996-04-25 1997-04-24 Use of dipeptidyl peptidase iv inhibitors (dpiv) for lowering the blood glucose level in mammals
DE122007000083C DE122007000083I1 (de) 1996-04-25 1997-04-24 Verwendung von aktivitätsmindernden effektoren der dipeptidyl peptidase iv zur senkung des blutglukosespiegels in säuger
KR1020107003160A KR20100036363A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도
KR1020057019835A KR20050104428A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성펩티다제의 활성억제제의 용도
KR1019980707018A KR100617676B1 (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는 데 효과가 있는 이가펩티드성 펩티다아제의 활성 억제제의 용도
CN97194017A CN1132578C (zh) 1996-04-25 1997-04-24 降低哺乳动物血糖水平的二肽基肽酶iv效应物的用途
DK97924866T DK0896538T3 (da) 1996-04-25 1997-04-24 Anvendelse af aktivitetsformindskende effektorer for dipeptidylpeptidase IV til sænkning af blodglucoseniveauet hos pattedyr
CA002252576A CA2252576C (en) 1996-04-25 1997-04-24 Use of dipeptidyl peptidase iv inhibitors for lowering the blood glucose level in mammals
EP97924866A EP0896538B1 (de) 1996-04-25 1997-04-24 Verwendung von aktivitätsmindernden effektoren der dipeptidyl peptidase iv zur senkung des blutglukosespiegels in säugern
DE59703959T DE59703959D1 (de) 1996-04-25 1997-04-24 Verwendung von aktivitätsmindernden effektoren der dipeptidyl peptidase iv zur senkung des blutglukosespiegels in säugern
SI9730802T SI1084705T1 (sl) 1996-04-25 1997-04-24 Postopek za zniĹľanje ravni krvnega sladkorja pri sesalcih
PT97924866T PT896538E (pt) 1996-04-25 1997-04-24 Utilizacao de efectores da dipeptidilpeptidase iv que diminuem a sua actividade para baixar o teor em glucose no sangue em mamiferos
EP10184503.0A EP2289513A3 (de) 1996-04-25 1997-04-24 Verfahren zur Senkung des Blutglukosespiegels in Säugern
PT119496T PT1084705E (pt) 1996-04-25 1997-04-24 Processo para baixar o nível de glucose no sangue em mamíferos
KR1020077015000A KR100950722B1 (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성펩티다제의 활성억제제의 용도
CNB2003101131191A CN1269528C (zh) 1996-04-25 1997-04-24 降低哺乳动物血糖水平的二肽基肽酶iv效应物的用途
KR1020117031497A KR20120014064A (ko) 1996-04-25 1997-04-24 포유류에서 혈당을 낮추는데 효과가 있는 이가펩티드성 펩티다제의 활성억제제의 용도
PCT/DE1997/000820 WO1997040832A1 (de) 1996-04-25 1997-04-24 Verwendung von dipeptidyl peptidase iv effektoren zur senkung des blutglukosespiegels in säugern
RU98121213/14A RU2189233C2 (ru) 1996-04-25 1997-04-24 Применение снижающих активность эффекторов дипептидил пептидазы (dp iv) и соответственно энзима dp iv с аналогичной активностью для снижения уровня сахара в крови
JP53845397A JP2001510442A (ja) 1996-04-25 1997-04-24 哺乳動物の血糖値低下のためのジペプチジルペプチダーゼ▲ｉｖ▼エフェクターの使用
ES00119496.8T ES2505665T3 (es) 1996-04-25 1997-04-24 Procedimiento para bajar el nivel de glucosa en sangre en los mamíferos
ES97924866T ES2158562T3 (es) 1996-04-25 1997-04-24 Utilizacion de inhibidores de dipeptidil peptidasa iv para reducir el nivel de glucosa en la sangre en mamiferos.
DE200712000038 DE122007000038I1 (de) 1996-04-25 1997-04-24 Verwendung von Aktivit{tsmindernden Effektoren derDipeptidyl Peptidase IV zur Senkung des Blutglukosespiegels in S{ugern
HK01103193.8A HK1033420B (en) 1996-04-25 2001-05-07 Method for lowering blood glucose levels in mammals
GR20010401649T GR3036788T3 (en) 1996-04-25 2001-10-03 Use of dipeptidyl peptidase iv inhibitors for lowering the blood glucose level in mammals
US11/022,087 US20050107309A1 (en) 1996-04-25 2004-12-22 Use of dipeptidyl peptidase IV effectors for normalizing the blood glucose level in mammals
LU91334C LU91334I2 (fr) 1996-04-25 2007-04-18 Sitagliptin, ou un sel de celui-ci pharmaceutiquement acceptable, en particulier le sel phosphate (JANUVIA)
NL300280C NL300280I2 (nl) 1996-04-25 2007-04-25 Toepassing van activiteitsverminderende dipeptidylpeptidase IV-effectoren voor het verlagen van glucosespiegel van het bloed by zoogdieren.
NL300308C NL300308I2 (nl) 1996-04-25 2007-12-03 Toepassing van activiteits verminderende dipeptidylpeptidase
LU91382C LU91382I2 (fr) 1996-04-25 2007-12-05 Vildagliptine ou un de ses sels pharmaceutiquementacceptables - GALVUS
JP2008320714A JP2009137973A (ja) 1996-04-25 2008-12-17 哺乳動物の血糖値低下のためのジペプチジルペプチダーゼｉｖエフェクターの使用
JP2011284809A JP2012092136A (ja) 1996-04-25 2011-12-27 哺乳動物の血糖値低下のためのジペプチジルペプチダーゼｉｖエフェクターの使用
US13/458,484 US20130116290A1 (en) 1996-04-25 2012-04-27 Use of Dipeptidyl Peptidase IV Effectors for Normalizing the Blood Glucose Level in Mammals
LTPA2014045C LTPA2014045I1 (lt) 1996-04-25 2014-12-09 Kraujo gliukozės lygio žinduoliuose mažinimo būdas
LTPA2014044C LTPA2014044I1 (lt) 1996-04-25 2014-12-09 Kraujo gliukozės lygio žinduoliuose mažinimo būdas
LTPA2014043C LTPA2014043I1 (lt) 1996-04-25 2014-12-09 Kraujo gliukozės lygio žinduoliuose mažinimo būdas
LU92612C LU92612I2 (fr) 1996-04-25 2014-12-15 Vildagliptin et ses dérivés pharmaceutiquement acceptables (GALVUS)
LU92614C LU92614I2 (fr) 1996-04-25 2014-12-15 Linagliptin et ses dérivés pharmaceutiquement acceptables (TRAJENTA)
LU92613C LU92613I2 (fr) 1996-04-25 2014-12-15 Saxagliptin et ses dérivés pharmaceutiquement acceptables (ONGLYZA)
LU92615C LU92615I2 (fr) 1996-04-25 2014-12-15 Alogliptin et ses dérivés pharmaceutiquement acceptables (VIPIDIA)
LU92611C LU92611I2 (fr) 1996-04-25 2014-12-15 Sitagliptin et ses dérivés pharmaceutiquement acceptables (JANUVIA)
FR14C0089C FR14C0089I1 (fr) 1996-04-25 2014-12-18 Methode pour diminuer le taux de glucose sanguin des mammiferes
US15/042,892 US20170007582A1 (en) 1996-04-25 2016-02-12 Use of Dipeptidyl Peptidase IV Effectors for Normalizing the Blood Glucose Level in Mammals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19616486.9A DE19616486C5 (de) 1996-04-25 1996-04-25 Verfahren zur Senkung des Blutglukosespiegels in Säugern

Publications (3)

Publication Number Publication Date
DE19616486A1 DE19616486A1 (de) 1997-10-30
DE19616486C2 DE19616486C2 (de) 1999-08-12
DE19616486C5 true DE19616486C5 (de) 2016-06-30

Family

ID=7792391

Family Applications (5)

Application Number Title Priority Date Filing Date
DE19616486.9A Expired - Lifetime DE19616486C5 (de) 1996-04-25 1996-04-25 Verfahren zur Senkung des Blutglukosespiegels in Säugern
DE122010000020C Pending DE122010000020I1 (de) 1996-04-25 1996-04-25 Verfahren zur Senkung des Blutglukosespiegels in Säugern
DE200712000038 Pending DE122007000038I1 (de) 1996-04-25 1997-04-24 Verwendung von Aktivit{tsmindernden Effektoren derDipeptidyl Peptidase IV zur Senkung des Blutglukosespiegels in S{ugern
DE59703959T Revoked DE59703959D1 (de) 1996-04-25 1997-04-24 Verwendung von aktivitätsmindernden effektoren der dipeptidyl peptidase iv zur senkung des blutglukosespiegels in säugern
DE122007000083C Pending DE122007000083I1 (de) 1996-04-25 1997-04-24 Verwendung von aktivitätsmindernden effektoren der dipeptidyl peptidase iv zur senkung des blutglukosespiegels in säuger

Family Applications After (4)

Application Number Title Priority Date Filing Date
DE122010000020C Pending DE122010000020I1 (de) 1996-04-25 1996-04-25 Verfahren zur Senkung des Blutglukosespiegels in Säugern
DE200712000038 Pending DE122007000038I1 (de) 1996-04-25 1997-04-24 Verwendung von Aktivit{tsmindernden Effektoren derDipeptidyl Peptidase IV zur Senkung des Blutglukosespiegels in S{ugern
DE59703959T Revoked DE59703959D1 (de) 1996-04-25 1997-04-24 Verwendung von aktivitätsmindernden effektoren der dipeptidyl peptidase iv zur senkung des blutglukosespiegels in säugern
DE122007000083C Pending DE122007000083I1 (de) 1996-04-25 1997-04-24 Verwendung von aktivitätsmindernden effektoren der dipeptidyl peptidase iv zur senkung des blutglukosespiegels in säuger

Country Status (21)

Country Link
US (1) US6303661B1 (https=)
EP (3) EP1084705B1 (https=)
JP (3) JP2001510442A (https=)
KR (5) KR100950722B1 (https=)
CN (2) CN1132578C (https=)
AT (1) ATE202705T1 (https=)
AU (1) AU721477C (https=)
CA (1) CA2252576C (https=)
DE (5) DE19616486C5 (https=)
DK (2) DK0896538T3 (https=)
ES (2) ES2158562T3 (https=)
FR (1) FR14C0089I1 (https=)
GR (1) GR3036788T3 (https=)
LT (3) LTPA2014045I1 (https=)
LU (7) LU91334I2 (https=)
NL (2) NL300280I2 (https=)
NZ (1) NZ332707A (https=)
PT (2) PT896538E (https=)
RU (1) RU2189233C2 (https=)
SI (1) SI1084705T1 (https=)
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