DE1617610C3 - Verfahren zum Herstellen eines Aerosol-Präparates für medizinische Zwecke - Google Patents

Verfahren zum Herstellen eines Aerosol-Präparates für medizinische Zwecke

Info

Publication number
DE1617610C3
DE1617610C3 DE1617610A DE1617610A DE1617610C3 DE 1617610 C3 DE1617610 C3 DE 1617610C3 DE 1617610 A DE1617610 A DE 1617610A DE 1617610 A DE1617610 A DE 1617610A DE 1617610 C3 DE1617610 C3 DE 1617610C3
Authority
DE
Germany
Prior art keywords
phenylephrine
aerosol
manufacture
aerosol preparation
ethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1617610A
Other languages
German (de)
English (en)
Other versions
DE1617610B2 (de
DE1617610A1 (de
Inventor
Frederick William Westfield N.J. Bollinger
Alan Jerome Shelton Conn. Davidson
Joel Benton Philadelphia Pa. Portnoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1617610A1 publication Critical patent/DE1617610A1/de
Publication of DE1617610B2 publication Critical patent/DE1617610B2/de
Application granted granted Critical
Publication of DE1617610C3 publication Critical patent/DE1617610C3/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE1617610A 1965-02-08 1966-02-07 Verfahren zum Herstellen eines Aerosol-Präparates für medizinische Zwecke Expired DE1617610C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43116465A 1965-02-08 1965-02-08

Publications (3)

Publication Number Publication Date
DE1617610A1 DE1617610A1 (de) 1972-04-20
DE1617610B2 DE1617610B2 (de) 1974-06-20
DE1617610C3 true DE1617610C3 (de) 1975-01-30

Family

ID=23710761

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1617610A Expired DE1617610C3 (de) 1965-02-08 1966-02-07 Verfahren zum Herstellen eines Aerosol-Präparates für medizinische Zwecke

Country Status (4)

Country Link
US (1) US3482015A (enExample)
DE (1) DE1617610C3 (enExample)
GB (1) GB1089043A (enExample)
NL (1) NL6601472A (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581225A (en) * 1984-04-25 1986-04-08 Eli Lilly And Company Sustained release intranasal formulation and method of use thereof
IL131492A0 (en) * 1997-04-30 2001-01-28 Warner Lambert Co Topical nasal antiinflammatory compositions
US20050187303A1 (en) * 2002-09-26 2005-08-25 Wu Men-Dar Therapeutic causing contraction of mucosal tissue, method of treating diseases relating to mucosal tissues, injector and therapeutic set
CA2499907C (en) * 2002-09-26 2011-06-28 Japan Science And Technology Agency Therapeutic causing contraction of mucosal tissue, method of treating diseases relating to mucosal tissues, injector and therapeutic set
US20040191176A1 (en) * 2003-03-28 2004-09-30 Kaplan Leonard W Formulations for treatment of pulmonary disorders
US20040235807A1 (en) * 2003-05-21 2004-11-25 Weinrich Karl P. Formulations including a topical decongestant and a topical corticosteroid suitable for nasal administration and method for treating obstructive sleep apnea

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629985A (enExample) * 1962-11-29
US3320125A (en) * 1964-04-28 1967-05-16 Merck & Co Inc Inhalation aerosol composition
GB1114313A (en) * 1964-11-19 1968-05-22 Wyeth John & Brother Ltd Pharmaceutical compositions

Also Published As

Publication number Publication date
GB1089043A (en) 1967-11-01
NL6601472A (enExample) 1966-08-09
DE1617610B2 (de) 1974-06-20
DE1617610A1 (de) 1972-04-20
US3482015A (en) 1969-12-02

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977
EHJ Ceased/non-payment of the annual fee