DE1518361B1 - L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung - Google Patents
L-Ornithin-L-asparaginat und Verfahren zu seiner HerstellungInfo
- Publication number
- DE1518361B1 DE1518361B1 DE19631518361 DE1518361A DE1518361B1 DE 1518361 B1 DE1518361 B1 DE 1518361B1 DE 19631518361 DE19631518361 DE 19631518361 DE 1518361 A DE1518361 A DE 1518361A DE 1518361 B1 DE1518361 B1 DE 1518361B1
- Authority
- DE
- Germany
- Prior art keywords
- ornithine
- aspartic acid
- asparaginate
- methanol
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/21—Synthetic spices, flavouring agents or condiments containing amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1654062 | 1962-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1518361B1 true DE1518361B1 (de) | 1969-11-13 |
Family
ID=11919082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19631518361 Pending DE1518361B1 (de) | 1962-04-23 | 1963-04-22 | L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung |
Country Status (7)
| Country | Link |
|---|---|
| AT (1) | AT246344B (enrdf_load_stackoverflow) |
| BR (1) | BR6348588D0 (enrdf_load_stackoverflow) |
| CH (1) | CH434285A (enrdf_load_stackoverflow) |
| DE (1) | DE1518361B1 (enrdf_load_stackoverflow) |
| DK (1) | DK109694C (enrdf_load_stackoverflow) |
| FR (1) | FR4048M (enrdf_load_stackoverflow) |
| GB (1) | GB965637A (enrdf_load_stackoverflow) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE789856A (fr) * | 1971-10-13 | 1973-02-01 | Tixier Georges | Medicament a base de derives de la lysine susceptibles de stimuler differents metabolismes, en particulier la genese des leucocytes |
| US3832465A (en) * | 1971-12-09 | 1974-08-27 | H Ghadimi | Injectable amino acid composition commensurate to the anabolic need of the body and method of using same |
| FR2495608A1 (fr) * | 1980-12-04 | 1982-06-11 | Morelle Jean | Nouveaux derives de l'acide aspartique et leurs usages |
| US4972634A (en) * | 1989-01-19 | 1990-11-27 | Dresden Gregory M | Portable walling |
| EP0477991B1 (en) * | 1990-09-28 | 1994-12-28 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing crystals of salt of acidic amino acid and basic amino acid |
| SI2153870T1 (sl) | 2004-11-26 | 2014-05-30 | Ucl Business Plc | Sestavki, ki obsegajo ornitin in fenilacetat ali fenilbutirat, za zdravljenje hepatitične encefalopatije |
| KR101975726B1 (ko) | 2009-04-03 | 2019-05-07 | 오세라 테라퓨틱스, 아이엔씨. | L-오르니틴 페닐 아세테이트, 및 이의 제조방법 |
| CA2764587C (en) | 2009-06-08 | 2018-04-24 | Ucl Business Plc | Treatment of portal hypertension and restoration of liver function using l-ornithine phenylacetate |
| AU2011312042B2 (en) | 2010-10-06 | 2015-08-20 | Ocera Therapeutics, Inc. | Methods of making L-ornithine phenyl acetate |
| CN102993037B (zh) * | 2012-11-20 | 2015-03-04 | 南京工业大学 | 一种l-鸟氨酸苯乙酸盐的制备方法 |
| KR20230018526A (ko) | 2014-11-24 | 2023-02-07 | 유씨엘 비즈니스 리미티드 | 암모니아-저감 치료를 이용한 간성상세포 활성화와 연관된 질병의 치료 |
| CN108024968B (zh) * | 2015-07-24 | 2022-07-05 | 赢创运营有限公司 | 门冬氨酸鸟氨酸的泡腾制剂 |
| US10835506B2 (en) | 2015-08-18 | 2020-11-17 | Ocera Therapeutics, Inc. | Treatment and prevention of muscle loss using L-ornithine in combination with at least one of phenylacetate and phenylbutyrate |
| IL270413B (en) | 2017-05-11 | 2022-08-01 | Ocera Therapeutics Inc | Processes of making l-ornithine phenylacetate |
-
1963
- 1963-04-10 GB GB14309/63A patent/GB965637A/en not_active Expired
- 1963-04-19 DK DK184763AA patent/DK109694C/da active
- 1963-04-22 CH CH502063A patent/CH434285A/de unknown
- 1963-04-22 DE DE19631518361 patent/DE1518361B1/de active Pending
- 1963-04-22 BR BR148588/63A patent/BR6348588D0/pt unknown
- 1963-04-23 AT AT327763A patent/AT246344B/de active
- 1963-07-19 FR FR931676A patent/FR4048M/fr not_active Expired
Non-Patent Citations (1)
| Title |
|---|
| None * |
Also Published As
| Publication number | Publication date |
|---|---|
| GB965637A (en) | 1964-08-06 |
| CH434285A (de) | 1967-04-30 |
| DK109694C (da) | 1968-06-10 |
| FR4048M (enrdf_load_stackoverflow) | 1966-04-04 |
| BR6348588D0 (pt) | 1973-07-03 |
| AT246344B (de) | 1966-04-12 |
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