DE1518361B1 - L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung - Google Patents

L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung

Info

Publication number
DE1518361B1
DE1518361B1 DE19631518361 DE1518361A DE1518361B1 DE 1518361 B1 DE1518361 B1 DE 1518361B1 DE 19631518361 DE19631518361 DE 19631518361 DE 1518361 A DE1518361 A DE 1518361A DE 1518361 B1 DE1518361 B1 DE 1518361B1
Authority
DE
Germany
Prior art keywords
ornithine
aspartic acid
asparaginate
methanol
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19631518361
Other languages
German (de)
English (en)
Inventor
Kyuji Abe
Mitsutaka Kawazu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of DE1518361B1 publication Critical patent/DE1518361B1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/21—Synthetic spices, flavouring agents or condiments containing amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19631518361 1962-04-23 1963-04-22 L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung Pending DE1518361B1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1654062 1962-04-23

Publications (1)

Publication Number Publication Date
DE1518361B1 true DE1518361B1 (de) 1969-11-13

Family

ID=11919082

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19631518361 Pending DE1518361B1 (de) 1962-04-23 1963-04-22 L-Ornithin-L-asparaginat und Verfahren zu seiner Herstellung

Country Status (7)

Country Link
AT (1) AT246344B (cg-RX-API-DMAC10.html)
BR (1) BR6348588D0 (cg-RX-API-DMAC10.html)
CH (1) CH434285A (cg-RX-API-DMAC10.html)
DE (1) DE1518361B1 (cg-RX-API-DMAC10.html)
DK (1) DK109694C (cg-RX-API-DMAC10.html)
FR (1) FR4048M (cg-RX-API-DMAC10.html)
GB (1) GB965637A (cg-RX-API-DMAC10.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789856A (fr) * 1971-10-13 1973-02-01 Tixier Georges Medicament a base de derives de la lysine susceptibles de stimuler differents metabolismes, en particulier la genese des leucocytes
US3832465A (en) * 1971-12-09 1974-08-27 H Ghadimi Injectable amino acid composition commensurate to the anabolic need of the body and method of using same
FR2495608A1 (fr) * 1980-12-04 1982-06-11 Morelle Jean Nouveaux derives de l'acide aspartique et leurs usages
US4972634A (en) * 1989-01-19 1990-11-27 Dresden Gregory M Portable walling
US5227007A (en) * 1990-09-28 1993-07-13 Kyowa Hakko Kogyo Co., Ltd. Process for producing crystals of salt of acidic amino acid and basic amino acid
PL1824563T3 (pl) 2004-11-26 2010-07-30 Ucl Business Plc Kompozycje zawierające ornitynę i fenylooctan lub fenylomaślan do leczenia encefalopatii wątrobowej
SMT201700601T1 (it) 2009-04-03 2018-03-08 Ocera Therapeutics Inc L-ornitina fenilacetato e metodi per la sua fabbricazione
MX2011013129A (es) 2009-06-08 2012-03-14 Ucl Business Plc Tratamiento de hipertension portal y restauracion de la funcion hepatica usando fenilacetato de l-ornitina.
CN103502203B (zh) 2010-10-06 2016-09-07 欧塞拉治疗有限公司 制备l-鸟氨酸苯基乙酸盐的方法
CN102993037B (zh) * 2012-11-20 2015-03-04 南京工业大学 一种l-鸟氨酸苯乙酸盐的制备方法
ES2769000T3 (es) 2014-11-24 2020-06-24 Ucl Business Ltd Tratamiento de enfermedades asociadas con la activación de células estrelladas hepáticas utilizando terapias reductoras de amoníaco
WO2017016930A1 (en) * 2015-07-24 2017-02-02 Evonik Technochemie Gmbh Effervescent formulations of ornithine aspartate
AU2016308641B2 (en) 2015-08-18 2022-02-03 Ocera Therapeutics, Inc. Treatment and prevention of muscle loss using L-ornithine in combination with at least one of phenylacetate and phenylbutyrate
EP3621947A4 (en) 2017-05-11 2021-03-10 Ocera Therapeutics, Inc. L-ORNITHINE PHENYLACETATE MANUFACTURING PROCESSES

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Also Published As

Publication number Publication date
BR6348588D0 (pt) 1973-07-03
FR4048M (cg-RX-API-DMAC10.html) 1966-04-04
CH434285A (de) 1967-04-30
DK109694C (da) 1968-06-10
AT246344B (de) 1966-04-12
GB965637A (en) 1964-08-06

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