DE1149010B - Verfahren zur Herstellung von 1-[2-Alkyl-4-aminopyrimidyl-(5)-methyl]-alkylpyridiniumsalzen - Google Patents

Verfahren zur Herstellung von 1-[2-Alkyl-4-aminopyrimidyl-(5)-methyl]-alkylpyridiniumsalzen

Info

Publication number
DE1149010B
DE1149010B DEM44190A DEM0044190A DE1149010B DE 1149010 B DE1149010 B DE 1149010B DE M44190 A DEM44190 A DE M44190A DE M0044190 A DEM0044190 A DE M0044190A DE 1149010 B DE1149010 B DE 1149010B
Authority
DE
Germany
Prior art keywords
methyl
amino
aminopyrimidyl
alkyl
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEM44190A
Other languages
German (de)
English (en)
Inventor
Edward Franklin Rogers
Lewis Hastings Sarett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1149010B publication Critical patent/DE1149010B/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
DEM44190A 1959-04-13 1960-02-03 Verfahren zur Herstellung von 1-[2-Alkyl-4-aminopyrimidyl-(5)-methyl]-alkylpyridiniumsalzen Pending DE1149010B (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US80568859A 1959-04-13 1959-04-13
US82997859A 1959-07-28 1959-07-28
US829979A US3020277A (en) 1959-04-13 1959-07-28 1-(2-n-propyl-4-amino-5-pyrimidyl-methyl)-2(or 4)-methyl pyridinium salts
US38451A US3065132A (en) 1959-04-13 1960-06-24 1-(2-methyl-4-amino-5-pyrimidylmethyl)-lower alkyl pyridinium quaternary salts for treating coccidiosis
US38449A US3020200A (en) 1959-04-13 1960-06-24 1-(2-alkyl-4-amino-5-pyrimidinylmethyl)-alkyl-pyridinium quaternary salts for treating coccidiosis

Publications (1)

Publication Number Publication Date
DE1149010B true DE1149010B (de) 1963-05-22

Family

ID=27534658

Family Applications (1)

Application Number Title Priority Date Filing Date
DEM44190A Pending DE1149010B (de) 1959-04-13 1960-02-03 Verfahren zur Herstellung von 1-[2-Alkyl-4-aminopyrimidyl-(5)-methyl]-alkylpyridiniumsalzen

Country Status (8)

Country Link
US (3) US3020277A (pt)
BE (1) BE587330A (pt)
CH (1) CH381694A (pt)
DE (1) DE1149010B (pt)
FI (1) FI43598B (pt)
FR (1) FR1291531A (pt)
GB (1) GB911551A (pt)
SE (2) SE308105B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545721B1 (de) * 1964-12-29 1971-01-21 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von 1-(2-Alkyl-4-amino-5-pyrimidylmethyl)-pyridinium-Verbindungen

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB984375A (en) * 1962-09-06 1965-02-24 Ici Ltd Veterinary compositions of sulphaquinoxaline and pyrimidine derivatives
US3374236A (en) * 1965-08-23 1968-03-19 Ciba Geigy Corp Quaternary 5-ammoniummethyl-4-amino-2-alkylmercaptoalkylene pyrimidine salts
GB1168801A (en) * 1966-05-13 1969-10-29 May & Baker Ltd Quinoline Derivatives
DE2251687A1 (de) * 1971-11-01 1973-05-10 Chinoin Gyogyszer Es Vegyeszet Neue quaternaere ammoniumverbindungen und verfahren zur herstellung derselben
US4044133A (en) * 1974-04-18 1977-08-23 Merck & Co., Inc. Anticoccidial compositions
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
CN105434362B (zh) * 2015-11-11 2018-01-19 浙江大洋生物科技集团股份有限公司 高纯度颗粒型盐酸氨丙啉的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587262A (en) * 1952-02-26 Chs chzghjoh

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2895874A (en) * 1953-03-27 1959-07-21 Whitmoyer Lab Inc Diamino-pyrimidine compositions for chemotherapy of coccidiosis
US2823160A (en) * 1955-03-29 1958-02-11 Whitmoyer Lab Inc Substituted pyrimidines compositions for chemotherapy of coccidiosis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587262A (en) * 1952-02-26 Chs chzghjoh

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545721B1 (de) * 1964-12-29 1971-01-21 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von 1-(2-Alkyl-4-amino-5-pyrimidylmethyl)-pyridinium-Verbindungen

Also Published As

Publication number Publication date
SE308105B (pt) 1969-02-03
FR1291531A (fr) 1962-04-27
SE311801B (pt) 1969-06-23
US3020200A (en) 1962-02-06
CH381694A (de) 1964-09-15
US3020277A (en) 1962-02-06
GB911551A (en) 1962-11-28
BE587330A (pt) 1900-01-01
US3065132A (en) 1962-11-20
FI43598B (pt) 1971-02-01

Similar Documents

Publication Publication Date Title
DE1695959C3 (de) 6-Amino-1,2-dihydro-1 -hydroxy-2imino-4-phenoxy-pyrimidine
DE2110445B2 (de) 1 -Benzyl-tetrahydro-2-( 1 H)py rimidone
DE2162011C3 (de) 2-Phenyl-3-(4-methyl-piperazinocarbonyloxy)-1-isoindolinon-derivate, ihre Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE2505297A1 (de) Neue 2-arylamino-2-imidazolinderivate und ein verfahren zu deren herstellung
DE1149010B (de) Verfahren zur Herstellung von 1-[2-Alkyl-4-aminopyrimidyl-(5)-methyl]-alkylpyridiniumsalzen
CH500983A (de) Verfahren zur Herstellung von 1-Amino-isochinolinen
DE1164416B (de) Verfahren zur Herstellung von in 3-Stellung aminoalkylierten Derivaten des 1-(5-Nitrofurfuryliden-amino)-hydantoins und ihren Salzen
DE2035573A1 (de) Neue Imidazolderivate, ihre Herstellung und die sie enthaltenden medizinischen Zu sammensetzungen
DE2022656C3 (de) 2-(Nicotinoylaminoäthansulfonylamino) pyridin
DE1695545B2 (de) Substituierte Benzimidazole, Verfahren zu deren Herstellung sowie deren Verwendung bei der Bekämpfung von Wurmerkrankungen
DE3235459A1 (de) 1-cyan-2-methyl-3-(2'-(((5''-methyl-imidazol-4''-yl)-methyl)-thio)-aethyl)-guanidin z (cimetidin z) und verfahren zur herstellung desselben und von 1-cyan-2-methyl-3-(2'-(((5''-methyl--imidazol-4''-yl)-methyl)-thio)-aethyl)-guanidin a(cimetidin a) sowie das erstere enthaltende arzneimittel
DE2166270C3 (de) Nicotinoylaminoäthansulfonyl-2amino-thiazol
DE2355262B2 (de) 1-Piperidinsulfonylharnstoffe, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE2243789A1 (de) 1-aminoisochinolinderivate, ihre salze mit saeuren und quartaeren ammoniumsalze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
AT227699B (de) Verfahren zur Herstellung von neuen quaternären 1-(2-nied. Alkyl-4-amino-5-pyrimidyl-methyl)-nied. alkylpyridiniumsalzen
DE3204074C2 (pt)
DE1670539C3 (de) Diacylthiamine und Verfahren zu deren Herstellung
DE1235929B (de) Verfahren zur Herstellung von 2-(2'-Pyrazinyl)-benzimidazol und seinen Salzen
AT373588B (de) Verfahren zur herstellung von neuen substituierten 1-benzoyl-2-phenylimino-imidazolidinen und von deren salzen
DE1795487C3 (de) 5-Nitrofuran-Derivate. Ausscheidung aus: 1445556
DE1137441B (de) Verfahren zur Herstellung von 4-Sulfanilamidopyrimidinderivaten
AT277249B (de) Verfahren zur Herstellung von neuen Chinolinderivaten
AT243816B (de) Verfahren zur Herstellung von neuen Guanidinverbindungen
AT226732B (de) Verfahren zur Herstellung von neuen Guanidinverbindungen
DE1670379C3 (de) 2-(4'-Thiazolyl)-benzimidazole und deren Herstellung