DD275871A5 - Verfahren zur herstellung von derivaten von 9-deoxo-9a-aza-9a-homoerythromycin a - Google Patents

Verfahren zur herstellung von derivaten von 9-deoxo-9a-aza-9a-homoerythromycin a Download PDF

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Publication number
DD275871A5
DD275871A5 DD88321611A DD32161188A DD275871A5 DD 275871 A5 DD275871 A5 DD 275871A5 DD 88321611 A DD88321611 A DD 88321611A DD 32161188 A DD32161188 A DD 32161188A DD 275871 A5 DD275871 A5 DD 275871A5
Authority
DD
German Democratic Republic
Prior art keywords
aza
deoxo
reaction
homoerythromycin
formula
Prior art date
Application number
DD88321611A
Other languages
German (de)
English (en)
Inventor
Gene M Bright
Original Assignee
������@���Kk��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD275871A5 publication Critical patent/DD275871A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DD88321611A 1987-11-10 1988-11-09 Verfahren zur herstellung von derivaten von 9-deoxo-9a-aza-9a-homoerythromycin a DD275871A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/002938 WO1989004167A1 (fr) 1987-11-10 1987-11-10 DERIVES A EFFET ANTIBACTERIEN DE 9a-ALLYLE ET 9a-PROPARGYLE DE 9-DESOXO-9a-AZA-9a-HOMOERYTHROMYCINE A

Publications (1)

Publication Number Publication Date
DD275871A5 true DD275871A5 (de) 1990-02-07

Family

ID=22202658

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88321611A DD275871A5 (de) 1987-11-10 1988-11-09 Verfahren zur herstellung von derivaten von 9-deoxo-9a-aza-9a-homoerythromycin a

Country Status (24)

Country Link
EP (1) EP0316128B1 (fr)
JP (1) JPH0631301B2 (fr)
KR (1) KR900008676B1 (fr)
CN (1) CN1018648B (fr)
AT (1) ATE86259T1 (fr)
AU (1) AU597194B2 (fr)
CA (1) CA1323026C (fr)
CS (1) CS272243B2 (fr)
DD (1) DD275871A5 (fr)
DE (1) DE3878835T2 (fr)
DK (1) DK623888A (fr)
ES (1) ES2053765T3 (fr)
GR (1) GR3007218T3 (fr)
IE (1) IE61282B1 (fr)
IL (1) IL88280A (fr)
MX (1) MX13723A (fr)
MY (1) MY104109A (fr)
NZ (1) NZ226907A (fr)
PH (1) PH25188A (fr)
PL (1) PL158151B1 (fr)
PT (1) PT88957B (fr)
WO (1) WO1989004167A1 (fr)
YU (1) YU46708B (fr)
ZA (1) ZA888364B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
HRP970714B1 (en) * 1997-12-31 2003-08-31 Pliva Pharm & Chem Works Beta,beta-disubstituted derivatives of 9-deoxo-9a-n-ethenyl-9a-aza-9a-homoerythromycin a
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020991A2 (en) 2002-12-12 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
CN103072186B (zh) * 2012-12-21 2015-04-01 山东大学 一种高阻尼性机床构件的精密成型方法
CN103669417B (zh) * 2013-12-17 2016-05-11 中国建筑第八工程局有限公司 预制地下室外墙接缝处环氧树脂水泥混凝土及其施工方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4464527A (en) * 1983-06-30 1984-08-07 Pfizer Inc. Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
US4465674A (en) * 1983-09-06 1984-08-14 Pfizer Inc. Azahomoerythromycin D derivative and intermediates therefor

Also Published As

Publication number Publication date
DE3878835D1 (de) 1993-04-08
YU208788A (en) 1990-02-28
ES2053765T3 (es) 1994-08-01
NZ226907A (en) 1990-09-26
IE61282B1 (en) 1994-10-19
GR3007218T3 (fr) 1993-07-30
PL158151B1 (en) 1992-08-31
PT88957B (pt) 1993-02-26
MY104109A (en) 1993-12-31
DE3878835T2 (de) 1993-06-09
IL88280A (en) 1993-08-18
EP0316128A3 (en) 1989-11-08
AU2496888A (en) 1989-05-11
CS740288A2 (en) 1990-03-14
CN1018648B (zh) 1992-10-14
PL275690A1 (en) 1989-06-12
EP0316128A2 (fr) 1989-05-17
ZA888364B (en) 1990-06-27
CN1038453A (zh) 1990-01-03
KR900008676B1 (ko) 1990-11-26
WO1989004167A1 (fr) 1989-05-18
IE883365L (en) 1989-05-10
EP0316128B1 (fr) 1993-03-03
ATE86259T1 (de) 1993-03-15
MX13723A (es) 1993-05-01
KR890008136A (ko) 1989-07-10
DK623888D0 (da) 1988-11-09
CA1323026C (fr) 1993-10-12
CS272243B2 (en) 1991-01-15
PH25188A (en) 1991-03-27
DK623888A (da) 1989-07-25
AU597194B2 (en) 1990-05-24
JPH01153632A (ja) 1989-06-15
IL88280A0 (en) 1989-06-30
JPH0631301B2 (ja) 1994-04-27
YU46708B (sh) 1994-04-05
PT88957A (pt) 1988-12-01

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Legal Events

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NPV Change in the person, the name or the address of the representative (addendum to changes before extension act)
ENJ Ceased due to non-payment of renewal fee