ATE86259T1 - Antibakterielle 9-deoxy-9a-allyl und propargyl-9a-aza-9a-homoerythromycin-a-derivate - Google Patents

Antibakterielle 9-deoxy-9a-allyl und propargyl-9a-aza-9a-homoerythromycin-a-derivate

Info

Publication number
ATE86259T1
ATE86259T1 AT88310465T AT88310465T ATE86259T1 AT E86259 T1 ATE86259 T1 AT E86259T1 AT 88310465 T AT88310465 T AT 88310465T AT 88310465 T AT88310465 T AT 88310465T AT E86259 T1 ATE86259 T1 AT E86259T1
Authority
AT
Austria
Prior art keywords
propargyl
allyl
antibacterial
homoerythromycin
aza
Prior art date
Application number
AT88310465T
Other languages
English (en)
Inventor
Gene Michael Bright
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE86259T1 publication Critical patent/ATE86259T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88310465T 1987-11-10 1988-11-07 Antibakterielle 9-deoxy-9a-allyl und propargyl-9a-aza-9a-homoerythromycin-a-derivate ATE86259T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1987/002938 WO1989004167A1 (en) 1987-11-10 1987-11-10 Antibacterial 9-deoxo-9a-allyl and propargyl-9a-aza-9a-homoerythromycin a derivatives
EP88310465A EP0316128B1 (de) 1987-11-10 1988-11-07 Antibakterielle 9-Deoxy-9a-allyl und Propargyl-9a-aza-9a-homoerythromycin-A-Derivate

Publications (1)

Publication Number Publication Date
ATE86259T1 true ATE86259T1 (de) 1993-03-15

Family

ID=22202658

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88310465T ATE86259T1 (de) 1987-11-10 1988-11-07 Antibakterielle 9-deoxy-9a-allyl und propargyl-9a-aza-9a-homoerythromycin-a-derivate

Country Status (24)

Country Link
EP (1) EP0316128B1 (de)
JP (1) JPH0631301B2 (de)
KR (1) KR900008676B1 (de)
CN (1) CN1018648B (de)
AT (1) ATE86259T1 (de)
AU (1) AU597194B2 (de)
CA (1) CA1323026C (de)
CS (1) CS272243B2 (de)
DD (1) DD275871A5 (de)
DE (1) DE3878835T2 (de)
DK (1) DK623888A (de)
ES (1) ES2053765T3 (de)
GR (1) GR3007218T3 (de)
IE (1) IE61282B1 (de)
IL (1) IL88280A (de)
MX (1) MX13723A (de)
MY (1) MY104109A (de)
NZ (1) NZ226907A (de)
PH (1) PH25188A (de)
PL (1) PL158151B1 (de)
PT (1) PT88957B (de)
WO (1) WO1989004167A1 (de)
YU (1) YU46708B (de)
ZA (1) ZA888364B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
HRP970714B1 (en) * 1997-12-31 2003-08-31 Pliva Pharm & Chem Works Beta,beta-disubstituted derivatives of 9-deoxo-9a-n-ethenyl-9a-aza-9a-homoerythromycin a
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020991A2 (en) 2002-12-12 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
CN103072186B (zh) * 2012-12-21 2015-04-01 山东大学 一种高阻尼性机床构件的精密成型方法
CN103669417B (zh) * 2013-12-17 2016-05-11 中国建筑第八工程局有限公司 预制地下室外墙接缝处环氧树脂水泥混凝土及其施工方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4464527A (en) * 1983-06-30 1984-08-07 Pfizer Inc. Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
US4465674A (en) * 1983-09-06 1984-08-14 Pfizer Inc. Azahomoerythromycin D derivative and intermediates therefor

Also Published As

Publication number Publication date
PL158151B1 (en) 1992-08-31
CS272243B2 (en) 1991-01-15
MY104109A (en) 1993-12-31
PT88957A (pt) 1988-12-01
WO1989004167A1 (en) 1989-05-18
GR3007218T3 (de) 1993-07-30
KR890008136A (ko) 1989-07-10
DE3878835D1 (de) 1993-04-08
YU46708B (sh) 1994-04-05
CN1038453A (zh) 1990-01-03
PL275690A1 (en) 1989-06-12
AU597194B2 (en) 1990-05-24
IL88280A0 (en) 1989-06-30
IE883365L (en) 1989-05-10
CA1323026C (en) 1993-10-12
DK623888A (da) 1989-07-25
YU208788A (en) 1990-02-28
EP0316128A2 (de) 1989-05-17
IE61282B1 (en) 1994-10-19
EP0316128A3 (en) 1989-11-08
PT88957B (pt) 1993-02-26
MX13723A (es) 1993-05-01
EP0316128B1 (de) 1993-03-03
PH25188A (en) 1991-03-27
DK623888D0 (da) 1988-11-09
JPH0631301B2 (ja) 1994-04-27
KR900008676B1 (ko) 1990-11-26
NZ226907A (en) 1990-09-26
AU2496888A (en) 1989-05-11
DE3878835T2 (de) 1993-06-09
IL88280A (en) 1993-08-18
CN1018648B (zh) 1992-10-14
ZA888364B (en) 1990-06-27
ES2053765T3 (es) 1994-08-01
JPH01153632A (ja) 1989-06-15
DD275871A5 (de) 1990-02-07
CS740288A2 (en) 1990-03-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee