DD234860A1 - Verfahren zur herstellung von s(-)-3-/3-acetyl-4-(3-tert-butylamino-2-hydroxypropoxy-phenyl/1,1-diaethylharnstoff - Google Patents

Verfahren zur herstellung von s(-)-3-/3-acetyl-4-(3-tert-butylamino-2-hydroxypropoxy-phenyl/1,1-diaethylharnstoff Download PDF

Info

Publication number
DD234860A1
DD234860A1 DD85274249A DD27424985A DD234860A1 DD 234860 A1 DD234860 A1 DD 234860A1 DD 85274249 A DD85274249 A DD 85274249A DD 27424985 A DD27424985 A DD 27424985A DD 234860 A1 DD234860 A1 DD 234860A1
Authority
DD
German Democratic Republic
Prior art keywords
acetyl
phenyl
pharmaceutically acceptable
tert
diethylurea
Prior art date
Application number
DD85274249A
Other languages
German (de)
English (en)
Inventor
Gerhard Zoelss
Richard Gratz
Karl Schloegl
Otmar Hofer
Robert J Gordon
Original Assignee
Chemie Linz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemie Linz Ag filed Critical Chemie Linz Ag
Publication of DD234860A1 publication Critical patent/DD234860A1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Epoxy Compounds (AREA)
DD85274249A 1984-03-21 1985-03-19 Verfahren zur herstellung von s(-)-3-/3-acetyl-4-(3-tert-butylamino-2-hydroxypropoxy-phenyl/1,1-diaethylharnstoff DD234860A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843410380 DE3410380A1 (de) 1984-03-21 1984-03-21 S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen

Publications (1)

Publication Number Publication Date
DD234860A1 true DD234860A1 (de) 1986-04-16

Family

ID=6231193

Family Applications (2)

Application Number Title Priority Date Filing Date
DD85274250A DD232489A1 (de) 1984-03-21 1985-03-19 Verfahren zur herstellung von s(-)-3-(3-acetyl-4-(3-tert. butylamino-2-hydroxypropoxy)-phenyl)-1,1-diaethylharnstoff
DD85274249A DD234860A1 (de) 1984-03-21 1985-03-19 Verfahren zur herstellung von s(-)-3-/3-acetyl-4-(3-tert-butylamino-2-hydroxypropoxy-phenyl/1,1-diaethylharnstoff

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DD85274250A DD232489A1 (de) 1984-03-21 1985-03-19 Verfahren zur herstellung von s(-)-3-(3-acetyl-4-(3-tert. butylamino-2-hydroxypropoxy)-phenyl)-1,1-diaethylharnstoff

Country Status (21)

Country Link
EP (1) EP0155518B1 (el)
JP (1) JPS60209557A (el)
AT (1) ATE45945T1 (el)
AU (1) AU567797B2 (el)
CA (1) CA1236116A (el)
CS (2) CS250682B2 (el)
DD (2) DD232489A1 (el)
DE (2) DE3410380A1 (el)
DK (1) DK124585A (el)
ES (1) ES541424A0 (el)
FI (1) FI83636C (el)
GR (1) GR850496B (el)
HU (1) HU193596B (el)
IL (1) IL74383A (el)
NO (1) NO161254C (el)
PL (2) PL143883B1 (el)
PT (1) PT80135B (el)
RO (2) RO91353B (el)
SU (2) SU1333235A3 (el)
YU (2) YU45707B (el)
ZA (1) ZA852086B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3636209A1 (de) * 1986-10-24 1988-04-28 Lentia Gmbh Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates
AT388099B (de) * 1986-11-26 1989-04-25 Chemie Holding Ag Verfahren zur hestellung von festen arzneiformen von (3-(3-acetyl-4-(3-tert. butylamino-2-hydroxypropoxy)-phenyl)-1,1-diethylharnstoff)- hydrochlorid
US4931557A (en) * 1988-10-17 1990-06-05 Eli Lilly And Company Method of resolving cis 3-amino-4-(2-furyl)vinyl)-1-methoxycarbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof
DE59003337D1 (de) * 1989-10-16 1993-12-09 Danubia Petrochem Polymere Pressling mit retardierter Wirkstofffreisetzung.
DE3935736A1 (de) * 1989-10-27 1991-05-02 Chemie Linz Deutschland Pressling mit retardierter wirkstofffreisetzung
US5227526A (en) * 1992-06-16 1993-07-13 Mallinckrodt Specialty Chemicals Company Resolution of 3-dimethylamino-2-methylpropiophenone (3-DAMP)
CN101239937B (zh) * 2007-02-07 2010-05-19 上海雅本化学有限公司 一种光学活性r-(-)-1-苄氧羰基-3-氨基吡咯烷及其盐酸盐的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT334385B (de) * 1973-12-20 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen
HU170678B (el) * 1973-12-20 1977-08-28
HU170677B (el) * 1973-12-21 1977-08-28
US4470965A (en) * 1982-10-27 1984-09-11 Usv Pharmaceutical Corporation Celiprolol for the treatment of glaucoma

Also Published As

Publication number Publication date
DE3410380A1 (de) 1985-10-10
GR850496B (el) 1985-03-15
NO161254C (no) 1989-07-26
EP0155518B1 (de) 1989-08-30
SU1309908A3 (ru) 1987-05-07
JPS60209557A (ja) 1985-10-22
EP0155518A2 (de) 1985-09-25
ES8603390A1 (es) 1985-12-16
HU193596B (en) 1987-11-30
YU45707B (sh) 1992-07-20
FI850860A0 (fi) 1985-03-04
ATE45945T1 (de) 1989-09-15
PT80135B (pt) 1987-10-20
YU45246B (en) 1992-05-28
FI83636C (fi) 1991-08-12
RO91352A (ro) 1987-04-30
NO850834L (no) 1985-09-23
FI850860L (fi) 1985-09-22
FI83636B (fi) 1991-04-30
PL252462A1 (en) 1985-11-19
SU1333235A3 (ru) 1987-08-23
PL252463A1 (en) 1985-11-19
AU567797B2 (en) 1987-12-03
DD232489A1 (de) 1986-01-29
RO91353B (ro) 1987-05-01
ZA852086B (en) 1985-11-27
RO91353A (ro) 1987-04-30
IL74383A0 (en) 1985-05-31
DE3572656D1 (en) 1989-10-05
AU3972285A (en) 1985-09-26
CS250683B2 (en) 1987-05-14
PT80135A (de) 1985-04-01
IL74383A (en) 1988-09-30
HUT37392A (en) 1985-12-28
YU44385A (en) 1987-06-30
ES541424A0 (es) 1985-12-16
RO91352B (ro) 1987-05-02
EP0155518A3 (en) 1986-06-25
CS250682B2 (en) 1987-05-14
CA1236116A (en) 1988-05-03
PL143883B1 (en) 1988-03-31
DK124585A (da) 1985-09-22
DK124585D0 (da) 1985-03-20
NO161254B (no) 1989-04-17
YU44485A (en) 1987-06-30

Similar Documents

Publication Publication Date Title
DD234860A1 (de) Verfahren zur herstellung von s(-)-3-/3-acetyl-4-(3-tert-butylamino-2-hydroxypropoxy-phenyl/1,1-diaethylharnstoff
DE69105859T2 (de) Thioharnstoffderivate und sie enthaltendes antimikrobielles Mittel und sie enthaltendes Mittel gegen Magengeschwüre.
DE60219500T2 (de) Neue phenylethanolaminverbindungen mit erregender wirkung an beta2-akzeptor und verfahren zu deren herstellung
DE2711719C2 (de) 3,4-Dihydrocarbostyril-Derivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
DE68916920T2 (de) Acyloxypropanolamine.
EP0030380A1 (de) 2,3-Indoldionderivate, Verfahren zu ihrer Herstellung, Zwischenprodukte, Arzneimittel enthaltend solche 2,3-Indoldionderivate und ihre pharmazeutische Verwendung
DE2724478C2 (de) 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DD148215A5 (de) Verfahren zur herstellung von bicyclo eckige klammer auf 3.1.0 eckige klammer zu hexyl-substituierten carbonylaminophenoxyverbindungen
CH643830A5 (de) Bis-moranolin-derivate.
EP0025109B1 (de) 1-Benzoxepin-5(2H)-on-Derivate und ihre Salze sowie Verfahren zu deren Herstellung
AT345792B (de) Verfahren zur herstellung von neuen 1- disubstiuierten phenoxy-2-hydroxy-3-diphenylmethylamino- und - 3- (9'-fluorenylamino)-propanen sowie deren saeureadditionssalzen
EP0027928B1 (de) Piperidinderivate von 4,5-Dialkyl-3-hydroxy-pyrrol-2-carbonsäureestern, ihre Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE69003031T2 (de) 2-Amino-1,2,3,4-Tetrahydronaphthalin-Derivate mit kardiovaskularer Wirkung, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten.
EP0030688B1 (de) Piperidinderivate von 3-Hydroxy-thiophen-2-carbonsäureestern, ihre Herstellung und diese enthaltende pharmazeutische Zubereitungen
CH643250A5 (de) (3-alkylamino-2-hydroxypropoxy)-furan-2-carbonsaeureanilide.
EP0086256B1 (de) 1-(2,4-Dichlorphenoxy)-3-(3,4-dimethoxy-Beta-phenethylamino)-2-propanol, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zusammensetzungen
AT380232B (de) Verfahren zur herstellung von neuen s(-)-3-(3-acetyl-4-(3-tert. butylamino-2hydroxypropoxy)-phenyl)-1,1-diaethylharnstoff und dessen pharmazeutisch vertraeglichen saeureadditionssalzen
DE2200204A1 (de) Verfahren zur Herstellung neuer heterozyklischer Verbindungen
DE1593782B2 (de) 1-nitrilophenoxy- 2- hydroxy -3- tert.butylaminopropane, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0008108A2 (de) Aminopropanolderivate des 2-(o-Hydroxyphenyl)-pyrrols, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2025286C3 (de) Ajmalinderivate
AT298458B (de) Verfahren zur Herstellung von neuen 1-(4'-Acylaminophenoxy)-2-hydroxy-3-aminopropanen und von deren Säureadditionssalzen
DD298506A5 (de) Verfahren zur herstellung halogensubstituierter 1-phenoxy-3-alkylamino-propan-2-ole
DE1545714C (de) 4 eckige Klammer auf 1 Benzylpipendyl (2) eckige Klammer zu 2,2 diphenyl 1,3 dioxolane und Verfahren zu ihrer Herstellung
DE2844353A1 (de) Neue p-isopropylthiophenoxypropanolamine, verfahren zu deren herstellung und arzneimittel

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee