DE68916920T2 - Acyloxypropanolamine. - Google Patents
Acyloxypropanolamine.Info
- Publication number
- DE68916920T2 DE68916920T2 DE68916920T DE68916920T DE68916920T2 DE 68916920 T2 DE68916920 T2 DE 68916920T2 DE 68916920 T DE68916920 T DE 68916920T DE 68916920 T DE68916920 T DE 68916920T DE 68916920 T2 DE68916920 T2 DE 68916920T2
- Authority
- DE
- Germany
- Prior art keywords
- carbon atoms
- phenyl
- loweralkyl
- straight
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/12—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/285,008 US4935422A (en) | 1988-12-15 | 1988-12-15 | Acyloxypropanolamines |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68916920D1 DE68916920D1 (de) | 1994-08-25 |
DE68916920T2 true DE68916920T2 (de) | 1994-12-01 |
Family
ID=23092348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68916920T Expired - Fee Related DE68916920T2 (de) | 1988-12-15 | 1989-12-12 | Acyloxypropanolamine. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4935422A (de) |
EP (1) | EP0373593B1 (de) |
JP (1) | JPH02258750A (de) |
AT (1) | ATE108765T1 (de) |
AU (1) | AU639672B2 (de) |
CA (1) | CA2005372A1 (de) |
DE (1) | DE68916920T2 (de) |
DK (1) | DK634589A (de) |
FI (1) | FI895979A0 (de) |
HU (1) | HU204025B (de) |
IL (1) | IL92651A0 (de) |
MY (1) | MY129948A (de) |
NO (1) | NO895043L (de) |
NZ (1) | NZ231753A (de) |
PT (1) | PT92591B (de) |
RU (1) | RU1776257C (de) |
ZA (1) | ZA899621B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5629345A (en) * | 1993-07-23 | 1997-05-13 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
US5965620A (en) * | 1993-07-23 | 1999-10-12 | Vide Pharmaceuticals | Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure |
US7074828B2 (en) * | 2002-12-05 | 2006-07-11 | The Governors Of The University Of Alberta | Compounds that stimulate glucose utilization and methods of use |
US7084173B2 (en) * | 2001-03-30 | 2006-08-01 | The Governors Of The Univerity Of Alberta | Compounds that stimulate glucose utilization and methods of use |
CA2477604A1 (en) | 2002-03-13 | 2003-09-25 | Signum Biosciences, Inc. | Modulation of protein methylation and phosphoprotein phosphate |
US7524885B2 (en) * | 2002-04-01 | 2009-04-28 | The Governors Of The University Of Alberta | Compounds that stimulate glucose utilization and methods of use |
WO2006084033A1 (en) * | 2005-02-03 | 2006-08-10 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
US7923041B2 (en) | 2005-02-03 | 2011-04-12 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
US9486441B2 (en) | 2008-04-21 | 2016-11-08 | Signum Biosciences, Inc. | Compounds, compositions and methods for making the same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5697253A (en) * | 1979-09-10 | 1981-08-05 | Union Carbide Corp | Wet adhesive aid |
US4692446A (en) * | 1981-11-12 | 1987-09-08 | E. I. Du Pont De Nemours & Co., Inc. | Esters of aryloxypropanolamine derivatives and medicinal uses |
ZA827646B (en) * | 1981-11-12 | 1983-08-31 | American Hospital Supply Corp | Esters of aryloxypropanolamine derivatives |
US4582855A (en) * | 1981-11-12 | 1986-04-15 | American Hospital Supply Corporation | Aromatic and esters of hydroxypropylamines |
US4959390A (en) * | 1988-12-15 | 1990-09-25 | E. I. Du Pont De Nemours And Company | Polyhydroxybenzyloxypropanolamines |
US4966914A (en) * | 1988-12-15 | 1990-10-30 | E. I. Du Pont De Nemours And Company | Oculoselective beta-blockers as antiglaucoma agents |
US4897417A (en) * | 1988-12-15 | 1990-01-30 | E. I. Du Pont De Nemours & Co. | Prodrugs of 3,4-hydroxy benzoyloxypropanolamines |
-
1988
- 1988-12-15 US US07/285,008 patent/US4935422A/en not_active Expired - Fee Related
-
1989
- 1989-12-12 DE DE68916920T patent/DE68916920T2/de not_active Expired - Fee Related
- 1989-12-12 IL IL92651A patent/IL92651A0/xx unknown
- 1989-12-12 EP EP89122923A patent/EP0373593B1/de not_active Expired - Lifetime
- 1989-12-12 AT AT89122923T patent/ATE108765T1/de not_active IP Right Cessation
- 1989-12-13 CA CA002005372A patent/CA2005372A1/en not_active Abandoned
- 1989-12-13 NZ NZ231753A patent/NZ231753A/en unknown
- 1989-12-14 RU SU894742927A patent/RU1776257C/ru active
- 1989-12-14 NO NO89895043A patent/NO895043L/no unknown
- 1989-12-14 FI FI895979A patent/FI895979A0/fi not_active Application Discontinuation
- 1989-12-14 DK DK634589A patent/DK634589A/da not_active Application Discontinuation
- 1989-12-14 MY MYPI89001766A patent/MY129948A/en unknown
- 1989-12-15 JP JP1324207A patent/JPH02258750A/ja active Pending
- 1989-12-15 ZA ZA899621A patent/ZA899621B/xx unknown
- 1989-12-15 HU HU896638A patent/HU204025B/hu not_active IP Right Cessation
- 1989-12-15 AU AU46797/89A patent/AU639672B2/en not_active Ceased
- 1989-12-15 PT PT92591A patent/PT92591B/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU639672B2 (en) | 1993-08-05 |
PT92591B (pt) | 1995-09-12 |
DE68916920D1 (de) | 1994-08-25 |
HUT53592A (en) | 1990-11-28 |
ZA899621B (en) | 1991-08-28 |
NZ231753A (en) | 1991-07-26 |
IL92651A0 (en) | 1990-08-31 |
HU896638D0 (en) | 1990-02-28 |
US4935422A (en) | 1990-06-19 |
EP0373593B1 (de) | 1994-07-20 |
EP0373593A2 (de) | 1990-06-20 |
AU4679789A (en) | 1990-06-21 |
NO895043D0 (no) | 1989-12-14 |
MY129948A (en) | 2007-05-31 |
DK634589A (da) | 1990-06-16 |
DK634589D0 (da) | 1989-12-14 |
FI895979A0 (fi) | 1989-12-14 |
RU1776257C (ru) | 1992-11-15 |
JPH02258750A (ja) | 1990-10-19 |
CA2005372A1 (en) | 1990-06-15 |
HU204025B (en) | 1991-11-28 |
ATE108765T1 (de) | 1994-08-15 |
PT92591A (pt) | 1990-06-29 |
EP0373593A3 (de) | 1991-03-20 |
NO895043L (no) | 1990-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |