DE69003031T2 - 2-Amino-1,2,3,4-Tetrahydronaphthalin-Derivate mit kardiovaskularer Wirkung, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten. - Google Patents

2-Amino-1,2,3,4-Tetrahydronaphthalin-Derivate mit kardiovaskularer Wirkung, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten.

Info

Publication number
DE69003031T2
DE69003031T2 DE90111831T DE69003031T DE69003031T2 DE 69003031 T2 DE69003031 T2 DE 69003031T2 DE 90111831 T DE90111831 T DE 90111831T DE 69003031 T DE69003031 T DE 69003031T DE 69003031 T2 DE69003031 T2 DE 69003031T2
Authority
DE
Germany
Prior art keywords
amino
preparation
pharmaceutical compositions
compositions containing
cardiovascular activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90111831T
Other languages
English (en)
Other versions
DE69003031D1 (de
Inventor
Paolo Chiesi
Stefano Bongrani
Maurizio Delcanale
Vittorino Servadio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Publication of DE69003031D1 publication Critical patent/DE69003031D1/de
Application granted granted Critical
Publication of DE69003031T2 publication Critical patent/DE69003031T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE90111831T 1989-06-27 1990-06-22 2-Amino-1,2,3,4-Tetrahydronaphthalin-Derivate mit kardiovaskularer Wirkung, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten. Expired - Fee Related DE69003031T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920996A IT1230931B (it) 1989-06-27 1989-06-27 Derivati di 2 ammino 1,2,3,4 tetraidronaftalene ad attivita' cardiovascolare, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Publications (2)

Publication Number Publication Date
DE69003031D1 DE69003031D1 (de) 1993-10-07
DE69003031T2 true DE69003031T2 (de) 1993-12-16

Family

ID=11175160

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90111831T Expired - Fee Related DE69003031T2 (de) 1989-06-27 1990-06-22 2-Amino-1,2,3,4-Tetrahydronaphthalin-Derivate mit kardiovaskularer Wirkung, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten.

Country Status (18)

Country Link
US (1) US5096929A (de)
EP (1) EP0405344B1 (de)
JP (1) JPH0363253A (de)
KR (1) KR910000135A (de)
AT (1) ATE93837T1 (de)
AU (1) AU633931B2 (de)
CA (1) CA2019828A1 (de)
DE (1) DE69003031T2 (de)
DK (1) DK0405344T3 (de)
FI (1) FI903202A0 (de)
HU (1) HUT58276A (de)
IE (1) IE902313A1 (de)
IT (1) IT1230931B (de)
MA (1) MA21884A1 (de)
NO (1) NO173542C (de)
NZ (1) NZ234253A (de)
PT (1) PT94498A (de)
ZA (1) ZA904962B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2041211B1 (es) * 1992-02-17 1994-05-16 Uriach & Cia Sa J Procedimiento para la obtencion de nuevos dihidro y tetrahidronaftalenos.
JP3708624B2 (ja) * 1996-03-27 2005-10-19 キッセイ薬品工業株式会社 ３，４−ジ置換フェニルエタノールアミノテトラリンカルボン酸誘導体
US6711436B1 (en) 1997-08-08 2004-03-23 Duke University Compositions, apparatus and methods for facilitating surgical procedures
AU758370B2 (en) * 1997-08-08 2003-03-20 Duke University Compositions, apparatus and methods for facilitating surgical procedures

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2776993A (en) * 1954-06-09 1957-01-08 Gordon A Alles 1-paramethoxyphenyl-2-cyclopentylamino-1-propanol compounds
DE1618005A1 (de) * 1966-09-22 1971-09-09 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen
US4011258A (en) * 1973-06-21 1977-03-08 Aktiebolaget Draco Orally active bronchospasmolytic compounds
IT1218322B (it) * 1982-06-10 1990-04-12 Chiesi Farma Spa Derivati di 1,2,3,4-tetraidronaftalene,procedimento di preparazione e relative composizioni farmaceutiche
DE3660959D1 (de) * 1985-06-26 1988-11-24 Smithkline Beckman Corp Benz-trisubstituted 2-aminotetralins
IL79323A (en) * 1985-07-10 1990-03-19 Sanofi Sa Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them
IT1199339B (it) * 1986-12-23 1988-12-30 Sigma Tau Ind Farmaceuti N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono

Also Published As

Publication number Publication date
NZ234253A (en) 1992-04-28
MA21884A1 (fr) 1990-12-31
JPH0363253A (ja) 1991-03-19
DK0405344T3 (da) 1993-10-25
IT1230931B (it) 1991-11-08
NO173542B (no) 1993-09-20
FI903202A0 (fi) 1990-06-26
DE69003031D1 (de) 1993-10-07
HUT58276A (en) 1992-02-28
NO902838L (no) 1990-12-28
ZA904962B (en) 1991-04-24
ATE93837T1 (de) 1993-09-15
HU903990D0 (en) 1990-11-28
AU5783290A (en) 1991-01-10
IE902313A1 (en) 1991-01-16
NO173542C (no) 1993-12-29
IT8920996A0 (it) 1989-06-27
KR910000135A (ko) 1991-01-29
EP0405344A3 (en) 1991-02-06
US5096929A (en) 1992-03-17
EP0405344A2 (de) 1991-01-02
PT94498A (pt) 1991-02-08
NO902838D0 (no) 1990-06-26
CA2019828A1 (en) 1990-12-27
IE902313L (en) 1990-12-27
AU633931B2 (en) 1993-02-11
EP0405344B1 (de) 1993-09-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee