DD202505A5 - Neue orale dipyridamolformen - Google Patents
Neue orale dipyridamolformen Download PDFInfo
- Publication number
- DD202505A5 DD202505A5 DD82240722A DD24072282A DD202505A5 DD 202505 A5 DD202505 A5 DD 202505A5 DD 82240722 A DD82240722 A DD 82240722A DD 24072282 A DD24072282 A DD 24072282A DD 202505 A5 DD202505 A5 DD 202505A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- dipyridamole
- acid
- item
- excipients
- acidic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813124090 DE3124090A1 (de) | 1981-06-19 | 1981-06-19 | Neue orale dipyridamolformen |
Publications (1)
Publication Number | Publication Date |
---|---|
DD202505A5 true DD202505A5 (de) | 1983-09-21 |
Family
ID=6134913
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DD82240722A DD202505A5 (de) | 1981-06-19 | 1982-06-14 | Neue orale dipyridamolformen |
Country Status (27)
Country | Link |
---|---|
US (1) | US4427648A (fr) |
EP (1) | EP0068191B2 (fr) |
JP (1) | JPS5849312A (fr) |
KR (1) | KR880001090B1 (fr) |
AR (1) | AR228779A1 (fr) |
AT (1) | ATE17317T1 (fr) |
AU (1) | AU555951B2 (fr) |
CA (1) | CA1200496A (fr) |
DD (1) | DD202505A5 (fr) |
DE (2) | DE3124090A1 (fr) |
DK (1) | DK158540C (fr) |
ES (1) | ES8304797A1 (fr) |
FI (1) | FI80829C (fr) |
GB (1) | GB2101484B (fr) |
GR (1) | GR76503B (fr) |
HU (1) | HU186078B (fr) |
IE (1) | IE53543B1 (fr) |
IL (1) | IL66075A (fr) |
IN (1) | IN158513B (fr) |
MA (1) | MA19503A1 (fr) |
MX (1) | MX160712A (fr) |
MY (1) | MY8700727A (fr) |
NZ (1) | NZ201008A (fr) |
PH (1) | PH25637A (fr) |
PT (1) | PT75077B (fr) |
SU (1) | SU1151193A3 (fr) |
ZA (1) | ZA824315B (fr) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2470599A1 (fr) * | 1979-12-07 | 1981-06-12 | Panoz Donald | Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus |
DE3237575A1 (de) * | 1982-10-09 | 1984-04-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale mopidamolformen |
KR880002139B1 (ko) * | 1983-04-08 | 1988-10-17 | 베링거 인겔하임 리미티드 | 경구 투여용 정제의 제조방법 |
DE3314003A1 (de) * | 1983-04-18 | 1984-10-18 | Boehringer Ingelheim KG, 6507 Ingelheim | Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung |
DE3320583A1 (de) * | 1983-06-08 | 1984-12-13 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung |
DE3320582A1 (de) * | 1983-06-08 | 1984-12-13 | Dr. Karl Thomae Gmbh, 7950 Biberach | Gliquidonhaltige zubereitungsformen und verfahren zu ihrer herstellung |
JPS6051106A (ja) * | 1983-08-31 | 1985-03-22 | Yamanouchi Pharmaceut Co Ltd | 塩酸アモスラロ−ル持続性製剤 |
US4867984A (en) * | 1984-11-06 | 1989-09-19 | Nagin K. Patel | Drug in bead form and process for preparing same |
CA1323833C (fr) * | 1987-04-28 | 1993-11-02 | Yatindra M. Joshi | Compositions pharmaceutiques sous forme de granules et methode de fabrication |
GB8813032D0 (en) * | 1988-06-02 | 1988-07-06 | Boehringer Ingelheim Int | Antiviral pharmaceutical composition |
US5064656A (en) * | 1989-11-14 | 1991-11-12 | Dr. Gergely & Co. | Uncoated pharmaceutical reaction tablet |
JPH0674206B2 (ja) * | 1989-12-28 | 1994-09-21 | 田辺製薬株式会社 | 放出制御型製剤およびその製法 |
US5364646A (en) * | 1990-01-10 | 1994-11-15 | Dr. Karl Thomae Gmbh | Oral pharmaceutical forms of pimobendan |
US6300361B1 (en) * | 1990-07-25 | 2001-10-09 | Novartis Ag | Stabilized pharmaceutical compositions comprising acid donors |
HU222489B1 (hu) * | 1990-07-25 | 2003-07-28 | Novartis Ag. | Stabilizált gyógyszerkészítmények és eljárás az előállításukra |
EP0585355B1 (fr) * | 1991-05-20 | 1995-03-22 | Marion Laboratories, Inc. | Composition multicouche a liberation regulee |
US5302393A (en) * | 1991-07-11 | 1994-04-12 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Method for inhibiting biological degradation of implantation polymeric material, inhibitor thereof and implantation polymeric material containing the inhibitor |
US5270047A (en) * | 1991-11-21 | 1993-12-14 | Kauffman Raymond F | Local delivery of dipyridamole for the treatment of proliferative diseases |
DE19845358A1 (de) * | 1998-10-02 | 2000-04-06 | Roehm Gmbh | Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe |
EP1093814A1 (fr) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Utilisation du dipyridamole ou du mopidamol dans la fabrication d'un médicament pour le traitement et la prévention des troubles de la microcirculation dépendants de la fibrine |
US7064130B2 (en) * | 2001-04-20 | 2006-06-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders |
DE10149674A1 (de) | 2001-10-09 | 2003-04-24 | Apogepha Arzneimittel Gmbh | Orale Darreichungsformen für Propiverin oder seinen pharmazeutisch annehmbaren Salzen mit verlängerter Wirkstoffreisetzung |
JP4331930B2 (ja) * | 2001-10-17 | 2009-09-16 | 武田薬品工業株式会社 | 酸に不安定な薬物の高含量顆粒 |
US20030181488A1 (en) * | 2002-03-07 | 2003-09-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof |
JP2006516593A (ja) | 2003-02-07 | 2006-07-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Mmp−9依存性疾患の治療及び予防のためのジピリダモール又はモピダモールの使用 |
DE10306179A1 (de) | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
AU2004231306A1 (en) | 2003-04-24 | 2004-11-04 | Boehringer Ingelheim International Gmbh | Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors |
DE10339862A1 (de) * | 2003-08-29 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
EP1579862A1 (fr) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Utilisation des inhibiteurs de PDE III pour la réduction de la taille du coeur chez des mammifères souffrant d'insufficances cardiaques |
CA2566081A1 (fr) * | 2004-05-13 | 2005-12-01 | Boehringer Ingelheim International Gmbh | Utilisation de dipyridamole pour le traitement de la resistance a des inhibiteurs plaquettaires |
BG860Y1 (bg) * | 2004-09-17 | 2007-02-28 | "Софарма" Ад | Лекарствена форма на дипиридамол |
CA2602392A1 (fr) | 2005-03-22 | 2006-09-28 | Losan Pharma Gmbh | Ibuprofene solubilise |
US20070087056A1 (en) * | 2005-08-09 | 2007-04-19 | Claudia Guthmann | Pharmaceutical form with sustained pH-independent active ingredient release for active ingredients having strong pH-dependent solubility |
JP2009504796A (ja) * | 2005-08-22 | 2009-02-05 | ノバルティス アクチエンゲゼルシャフト | pH依存性薬剤化合物、pH調整剤および遅延剤を含む医薬組成物 |
GB0517204D0 (en) * | 2005-08-22 | 2005-09-28 | Novartis Ag | Organic compounds |
BRPI0707324A2 (pt) * | 2006-01-27 | 2011-05-03 | Eurand Inc | sistemas de fornecimento de fármaco compreendendo agente de bloqueio de serotonina 5-ht3 seletivo fracamente básico e ácidos orgánicos |
NZ569984A (en) * | 2006-01-27 | 2011-06-30 | Eurand Inc | Drug delivery systems comprising weakly basic drugs and organic acids |
AU2006337643A1 (en) * | 2006-02-09 | 2007-08-16 | Teva Pharmaceutical Industries Ltd. | Dipyridamole extended-release formulations and process for preparing same |
EP1920785A1 (fr) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Préparation liquide contenant un complexe du pimobendane et de la cyclodextrine |
CN101910113A (zh) | 2007-12-28 | 2010-12-08 | 怡百克制药公司 | 左旋多巴控释制剂及其用途 |
US20090196935A1 (en) * | 2008-02-01 | 2009-08-06 | Ahmed Salah U | Pharmaceutical Capsules Comprising Extended Release Dipyridamole Pellets |
US8133506B2 (en) * | 2008-03-12 | 2012-03-13 | Aptalis Pharmatech, Inc. | Drug delivery systems comprising weakly basic drugs and organic acids |
WO2010036975A2 (fr) * | 2008-09-25 | 2010-04-01 | Teva Pharmaceutical Industries Ltd. | Formulations de dipyridamole et d'acide acétylsalicylique et leur procédé de préparation |
US20110003005A1 (en) * | 2009-07-06 | 2011-01-06 | Gopi Venkatesh | Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions |
WO2011014741A1 (fr) * | 2009-07-31 | 2011-02-03 | Artemis Health, Inc. | Procédés et compositions pour la stabilisation de cellules |
EP2361615A1 (fr) | 2010-02-19 | 2011-08-31 | Alfred E. Tiefenbacher GmbH & Co. KG | Comprimé à libération prolongée de dipyridamole |
US20120301541A1 (en) * | 2011-05-24 | 2012-11-29 | Haronsky Elina | Compressed core for pharmaceutical composition |
EP2825159B1 (fr) | 2012-03-15 | 2022-06-22 | Boehringer Ingelheim Vetmedica GmbH | Formulation de comprimé pharmaceutique pour le secteur médical vétérinaire, son procédé de production et d'utilisation |
KR102455648B1 (ko) | 2013-07-19 | 2022-10-19 | 베링거잉겔하임베트메디카게엠베하 | 보존된 에테르화된 사이클로덱스트린 유도체 함유 액체 수성 약제학적 조성물 |
CA2926082C (fr) | 2013-10-07 | 2022-06-14 | Impax Laboratories, Inc. | Formulations mucoadhesives a liberation controlee de levodopa et/ou d'esters de levodopa et leurs utilisations |
US10987313B2 (en) | 2013-10-07 | 2021-04-27 | Impax Laboratories, Llc | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
BR112016011111B1 (pt) | 2013-12-04 | 2022-11-16 | Boehringer Ingelheim Vetmedica Gmbh | Composições farmacêuticas aprimoradas de pimobendan |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2157201C3 (de) * | 1970-11-13 | 1974-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verbesserte feste orale Applikationsform von Raubasin |
DE2700433A1 (de) * | 1977-01-07 | 1978-07-20 | Kali Chemie Pharma Gmbh | Arzneimittelzubereitungen mit verbesserten resorptionseigenschaften |
LU77353A1 (fr) * | 1977-05-16 | 1979-01-19 | ||
DD146547A5 (de) | 1978-07-15 | 1981-02-18 | Boehringer Sohn Ingelheim | Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen |
IE48715B1 (en) * | 1978-12-22 | 1985-05-01 | Elan Corp Plc | New galencial forms for administration of medicaments by oral route,with programmed release and processes for preparing same |
DE3000979A1 (de) * | 1980-01-12 | 1981-07-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue dipyridamol-retardformen und verfahren zu ihrer herstellung |
JPS6116368A (ja) * | 1984-07-02 | 1986-01-24 | Mitsubishi Electric Corp | 画像処理装置の検査装置 |
-
1981
- 1981-06-19 DE DE19813124090 patent/DE3124090A1/de active Granted
-
1982
- 1982-06-08 EP EP82105000A patent/EP0068191B2/fr not_active Expired - Lifetime
- 1982-06-08 DE DE8282105000T patent/DE3268380D1/de not_active Expired
- 1982-06-08 AT AT82105000T patent/ATE17317T1/de not_active IP Right Cessation
- 1982-06-11 IN IN440/DEL/82A patent/IN158513B/en unknown
- 1982-06-14 DD DD82240722A patent/DD202505A5/de not_active IP Right Cessation
- 1982-06-15 DK DK269682A patent/DK158540C/da not_active IP Right Cessation
- 1982-06-17 SU SU823452105A patent/SU1151193A3/ru active
- 1982-06-17 FI FI822173A patent/FI80829C/fi not_active IP Right Cessation
- 1982-06-17 IL IL66075A patent/IL66075A/xx not_active IP Right Cessation
- 1982-06-17 PH PH27760A patent/PH25637A/en unknown
- 1982-06-17 US US06/389,282 patent/US4427648A/en not_active Expired - Lifetime
- 1982-06-18 AU AU84965/82A patent/AU555951B2/en not_active Expired
- 1982-06-18 KR KR8202716A patent/KR880001090B1/ko active
- 1982-06-18 CA CA000405445A patent/CA1200496A/fr not_active Expired
- 1982-06-18 MA MA19710A patent/MA19503A1/fr unknown
- 1982-06-18 NZ NZ201008A patent/NZ201008A/en unknown
- 1982-06-18 GB GB08217665A patent/GB2101484B/en not_active Expired
- 1982-06-18 ES ES513235A patent/ES8304797A1/es not_active Expired
- 1982-06-18 JP JP57105258A patent/JPS5849312A/ja active Granted
- 1982-06-18 GR GR68477A patent/GR76503B/el not_active IP Right Cessation
- 1982-06-18 PT PT75077A patent/PT75077B/pt unknown
- 1982-06-18 AR AR289716A patent/AR228779A1/es active
- 1982-06-18 ZA ZA824315A patent/ZA824315B/xx unknown
- 1982-06-18 HU HU822003A patent/HU186078B/hu unknown
- 1982-06-18 IE IE1453/82A patent/IE53543B1/en not_active IP Right Cessation
- 1982-06-18 MX MX193236A patent/MX160712A/es unknown
-
1987
- 1987-12-30 MY MY727/87A patent/MY8700727A/xx unknown
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Legal Events
Date | Code | Title | Description |
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ENJ | Ceased due to non-payment of renewal fee |