DD140038A5 - Verfahren zur herstellung neuer guanidinverbindungen - Google Patents

Verfahren zur herstellung neuer guanidinverbindungen Download PDF

Info

Publication number
DD140038A5
DD140038A5 DD78205794A DD20579478A DD140038A5 DD 140038 A5 DD140038 A5 DD 140038A5 DD 78205794 A DD78205794 A DD 78205794A DD 20579478 A DD20579478 A DD 20579478A DD 140038 A5 DD140038 A5 DD 140038A5
Authority
DD
German Democratic Republic
Prior art keywords
compound
methyl
general formula
cyano
acid addition
Prior art date
Application number
DD78205794A
Other languages
German (de)
English (en)
Inventor
Ronnie R Crenshaw
George M Luke
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/848,959 external-priority patent/US4112234A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DD140038A5 publication Critical patent/DD140038A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD78205794A 1977-06-03 1978-06-05 Verfahren zur herstellung neuer guanidinverbindungen DD140038A5 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80300977A 1977-06-03 1977-06-03
US82679677A 1977-08-22 1977-08-22
US05/848,959 US4112234A (en) 1977-08-22 1977-11-07 Imidazolylmethylthioethyl alkynyl guanidines

Publications (1)

Publication Number Publication Date
DD140038A5 true DD140038A5 (de) 1980-02-06

Family

ID=27419995

Family Applications (1)

Application Number Title Priority Date Filing Date
DD78205794A DD140038A5 (de) 1977-06-03 1978-06-05 Verfahren zur herstellung neuer guanidinverbindungen

Country Status (26)

Country Link
JP (1) JPS543067A (es)
AR (2) AR222797A1 (es)
CA (1) CA1110251A (es)
CH (2) CH641167A5 (es)
CY (3) CY1231A (es)
DD (1) DD140038A5 (es)
DE (1) DE2824066A1 (es)
DK (1) DK243178A (es)
ES (3) ES470474A1 (es)
FI (1) FI69069C (es)
FR (2) FR2401143A1 (es)
GB (3) GB1598628A (es)
GR (1) GR73860B (es)
HK (3) HK38184A (es)
HU (1) HU186766B (es)
IE (1) IE47543B1 (es)
IL (1) IL54819A (es)
KE (1) KE3373A (es)
LU (1) LU79725A1 (es)
MY (3) MY8500452A (es)
NL (1) NL7805935A (es)
NO (3) NO152214C (es)
NZ (1) NZ187376A (es)
SE (3) SE443784B (es)
SG (1) SG8584G (es)
YU (4) YU129778A (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS568352A (en) * 1979-07-03 1981-01-28 Shionogi & Co Ltd Aminoalkylvenzene derivative
US4339439A (en) * 1981-01-19 1982-07-13 Bristol-Myers Company Pharmaceutical methods and compositions
JPS57134318A (en) * 1981-02-12 1982-08-19 Nissan Motor Co Ltd Air mixing construction of air conditioner
JPS5848516U (ja) * 1981-09-30 1983-04-01 日産車体株式会社 車両用空気調和装置
JPS6018010U (ja) * 1983-07-18 1985-02-07 日産自動車株式会社 車両用空気調和装置の温度調整機構
JPS60113211U (ja) * 1984-01-06 1985-07-31 松下電器産業株式会社 自動車用空気調和装置
ES2007948A6 (es) * 1988-07-06 1989-07-01 Vinas Lab Procedimiento para la obtencion de derivados propargilguanidicos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024271A (en) * 1971-03-09 1977-05-17 Smith Kline & French Laboratories Limited Pharmacologically active guanidine compounds
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
GB1531221A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for preparing guanidine derivatives

Also Published As

Publication number Publication date
IE47543B1 (en) 1984-04-18
NZ187376A (en) 1981-05-29
NO833255L (no) 1978-12-05
HU186766B (en) 1985-09-30
CH641167A5 (en) 1984-02-15
SE8401491D0 (sv) 1984-03-16
HK38084A (en) 1984-05-11
CY1230A (en) 1984-06-29
SE7806525L (sv) 1978-12-04
JPS543067A (en) 1979-01-11
ES478203A1 (es) 1979-06-01
IL54819A (en) 1983-03-31
NO152214B (no) 1985-05-13
GR73860B (es) 1984-05-08
FI69069C (fi) 1985-12-10
FR2436138A1 (fr) 1980-04-11
LU79725A1 (fr) 1979-02-02
KE3373A (en) 1984-03-23
DE2824066A1 (de) 1978-12-14
CY1229A (en) 1984-06-29
FR2401143A1 (fr) 1979-03-23
MY8500452A (en) 1985-12-31
IL54819A0 (en) 1978-07-31
GB1598629A (en) 1981-09-23
NO791637L (no) 1978-12-05
NO152214C (no) 1985-08-28
FI69069B (fi) 1985-08-30
DK243178A (da) 1978-12-04
SE8401491L (sv) 1984-03-16
FR2436138B1 (es) 1982-12-03
YU40624B (en) 1986-02-28
HK38284A (en) 1984-05-11
MY8500453A (en) 1985-12-31
FR2401143B1 (es) 1981-12-11
YU41620B (en) 1987-12-31
YU53079A (en) 1983-09-30
YU40625B (en) 1986-02-28
AR222503A1 (es) 1981-05-29
CY1231A (en) 1984-06-29
MY8500451A (en) 1985-12-31
GB1598628A (en) 1981-09-23
CH644591A5 (en) 1984-08-15
NL7805935A (nl) 1978-12-05
SE8401492L (sv) 1984-03-16
IE781112L (en) 1978-12-03
YU129778A (en) 1983-02-28
ES470474A1 (es) 1979-09-01
FI781737A (fi) 1978-12-04
GB1598630A (en) 1981-09-23
NO151824C (no) 1985-06-12
SE443784B (sv) 1986-03-10
SG8584G (en) 1985-02-08
HK38184A (en) 1984-05-11
NO781928L (no) 1978-12-05
SE8401492D0 (sv) 1984-03-16
CA1110251A (en) 1981-10-06
ES478202A1 (es) 1979-06-01
YU215582A (en) 1983-02-28
AR222797A1 (es) 1981-06-30
JPS5639313B2 (es) 1981-09-11
NO151824B (no) 1985-03-04
YU215482A (en) 1983-02-28

Similar Documents

Publication Publication Date Title
DE2557438C2 (es)
DD216929A5 (de) Verfahren zur herstellung von thiazolidinderivaten
DD233374A5 (de) Verfahren zur herstellung von 2-(n-subst.-guanidino)-4-heteroarylthiazole
DE19540995A1 (de) Substituierte Sulfonimidamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0153277A2 (de) Neue Pleuromutilinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
AT399338B (de) Neue substituierte benzamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die diese benzamide enthalten
DE2950838A1 (de) Neue thiazolylmethylthioderivate, verfahren zu deren herstellung und arzneimittel
DE2938990C2 (es)
DE3240727A1 (de) Ergolinderivate, verfahren zu deren herstellung sowie pharmazeutische zubereitungen, die diese enthalten
DD140038A5 (de) Verfahren zur herstellung neuer guanidinverbindungen
CH642066A5 (de) 3-indolyl-tert.-butylaminopropanole, verfahren zu deren herstellung und sie enthaltende pharmazeutische mittel.
DE2930608C2 (de) Alkylthiophenoxyalkylamine, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
CH645368A5 (de) 2-hydroxy-5-(1-hydroxy-2-piperazinylethyl)benzoesaeure-derivate sowie verfahren zu deren herstellung.
DE1934392C3 (de) Neue 2-Pyridylthioamide und Verfahren zu ihrer Herstellung
CH654575A5 (de) Antiarhythmisch wirksame phenaethylpiperidin-verbindungen.
DE2734270C2 (es)
US4200760A (en) Imidazolylalkylthioalkylamino-ethylene derivatives
EP0174459B1 (de) 9- beziehungsweise 11-(Nitro)-apovincaminsäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DD210909A5 (de) Verfahren zur herstellung von substituierten 3,4-diamino-1,2,5-thiadiazolverbindungen
AT375348B (de) Verfahren zur herstellung von imidazolylguanidinen und von deren salzen
DD253616A5 (de) Verfahren zur herstellung von neuen pleunromutilinderivaten
AT390790B (de) Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols
DE3107599C2 (de) N-Cyan-N'-methyl-N"-{2-[(5-methylthio-imidazol-4-yl)-methylthio]-äthyl}-guanidin, Verfahren zu seiner Herstellung und diese Verbindung enthaltende Arzneimittel
DE2628642C2 (de) In 2-Stellung substituierte 1,3-Diaza-fünfringkohlenstoffverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
DE2450161B2 (de) N-beta-(3',4'-dihydroxyphenaethyl)- glutamin und dessen alkylester sowie deren pharmakologisch vertraegliche saeureadditionssalze, verfahren zu deren herstellung und diese enthaltende arzneimittel