ES2007948A6 - Procedimiento para la obtencion de derivados propargilguanidicos. - Google Patents
Procedimiento para la obtencion de derivados propargilguanidicos.Info
- Publication number
- ES2007948A6 ES2007948A6 ES8802117A ES8802117A ES2007948A6 ES 2007948 A6 ES2007948 A6 ES 2007948A6 ES 8802117 A ES8802117 A ES 8802117A ES 8802117 A ES8802117 A ES 8802117A ES 2007948 A6 ES2007948 A6 ES 2007948A6
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- propargylguanidine
- preparation
- integer
- acid anions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS PROPARGILGUANIDINICOS DE FORMULA I DONDE: X ES UN ANION FARMACEUTICAMENTE ACEPTABLES; A ES UN NUMERO ENTERO DE 1 A 5; B ES UN NUMERO ENTERO DE 1 A 7; C ES CERO O UN NUMERO ENTERO DE 1 A 4; Y DE 2A - C, PARA ANIONES DE ACIDOS MONOVALENTES, ES A - C, PARA ANIONES DE ACIDOS DIVALENTES, Y ES CERO O 2 CUANDO C ES CERO, ITBASADO EN LA REACCION DE LA N-CIANO-NK-(2-((4-METIL-5-IMIDAZOLIL-METILTIO-ETIL)-NL-PROPARGIL-GUANIDINA CON UN COMPUESTO DE ZINC- QUE CONTIENE EL ANION X, O CON UN ORGANOZINC.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES8802117A ES2007948A6 (es) | 1988-07-06 | 1988-07-06 | Procedimiento para la obtencion de derivados propargilguanidicos. |
AT89500060T ATE80622T1 (de) | 1988-07-06 | 1989-05-23 | Propargylguanidin-derivate und verfahren zu deren herstellung. |
JP1131220A JPH0225469A (ja) | 1988-07-06 | 1989-05-23 | プロパルギルグアニジン誘導体及びその製造方法 |
EP89500060A EP0350422B1 (en) | 1988-07-06 | 1989-05-23 | Propargylguanidine derivatives and process for the preparation thereof |
DE8989500060T DE68902887T2 (de) | 1988-07-06 | 1989-05-23 | Propargylguanidin-derivate und verfahren zu deren herstellung. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES8802117A ES2007948A6 (es) | 1988-07-06 | 1988-07-06 | Procedimiento para la obtencion de derivados propargilguanidicos. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2007948A6 true ES2007948A6 (es) | 1989-07-01 |
Family
ID=8257175
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8802117A Expired ES2007948A6 (es) | 1988-07-06 | 1988-07-06 | Procedimiento para la obtencion de derivados propargilguanidicos. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0350422B1 (es) |
JP (1) | JPH0225469A (es) |
AT (1) | ATE80622T1 (es) |
DE (1) | DE68902887T2 (es) |
ES (1) | ES2007948A6 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9004328D0 (en) * | 1990-02-27 | 1990-04-25 | Glaxo Group Ltd | Chemical compounds |
GB9009240D0 (en) * | 1990-04-25 | 1990-06-20 | Glaxo Group Ltd | Chemical compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ187376A (en) * | 1977-06-03 | 1981-05-29 | Bristol Myers Co | N-cyano-n-(2-(4-methyl-5-imidazolyl)methylthio)ethyl)-n-alkynyl guanidines intermediates pharmaceutical compositions |
US4381395A (en) * | 1981-04-03 | 1983-04-26 | Sk & F Lab Co. | Process for preparing an imidazole derivative |
-
1988
- 1988-07-06 ES ES8802117A patent/ES2007948A6/es not_active Expired
-
1989
- 1989-05-23 JP JP1131220A patent/JPH0225469A/ja active Pending
- 1989-05-23 DE DE8989500060T patent/DE68902887T2/de not_active Expired - Fee Related
- 1989-05-23 AT AT89500060T patent/ATE80622T1/de not_active IP Right Cessation
- 1989-05-23 EP EP89500060A patent/EP0350422B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH0225469A (ja) | 1990-01-26 |
EP0350422B1 (en) | 1992-09-16 |
EP0350422A1 (en) | 1990-01-10 |
DE68902887D1 (de) | 1992-10-22 |
DE68902887T2 (de) | 1993-03-18 |
ATE80622T1 (de) | 1992-10-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUT53368A (en) | Process for producing pyrazolo-pyridine derivatives and pharmaceutical compositions containing them | |
TW223645B (es) | ||
HUT65868A (en) | Process for producing ortosubstituted benzoyl-guanidine derivatives and pharmaceutical preparations containing them | |
CA2110443A1 (en) | Guanidinealkyl-1,1-bisphosphonic acid derivatives, process for their preparation and their use | |
GR1002573B (el) | Μικροβιακη μεθοδος παρασκευης μεβινολινης. | |
HUT50116A (en) | Process for producing diurea derivatives and pharmaceutical compositions containing them | |
AU1384788A (en) | Method of improving sleep | |
BG51251A3 (en) | Method for the preparetion of tetrahydroimidazo /1,4/-benzodiazepine (?)-2-ketons | |
ES2007948A6 (es) | Procedimiento para la obtencion de derivados propargilguanidicos. | |
CS909186A2 (en) | Zpusob vyroby chinolinkarboxylovych kyselin | |
ES8205207A1 (es) | Un procedimiento para la preparacion de una sal de amina | |
ES2009921A6 (es) | Procedimiento para la obtencion de derivados imidazolicos. | |
HU903092D0 (en) | Process for the preparation of buten-carboxylic acid derivatives and pharmaceutical compositions containing such compounds | |
GB1409648A (en) | Substituted pyrrolidinemethanol compounds and pharmaceutical compositions thereof | |
ES8502118A1 (es) | Procedimiento de preparar derivados de penicilina. | |
EP0301718A3 (en) | Process for preparing novel diamines | |
IL86846A (en) | Pharmaceutical compositions for preventing and treating heart failure containing indane or naphthalene carboxylic acids | |
ES8205219A1 (es) | Un metodo para producir un compuesto de hidrouracilo | |
MY105374A (en) | A process for the preparation of 7-amino-3-methoxymeth- yl-ceph-3-em-4-carboxylic acid. | |
PT83192A (en) | Process for preparing unsaturated compounds useful in the treatment of cardiovascular phatological conditions containing 1,4-di-hydropiridine-3,5-dicarboxylic acid derivatives | |
JPS57212167A (en) | Guanidine derivative and its preparation | |
JPS525755A (en) | Process for preparation of 3-amino-4-homotwistane and its acid salts | |
EP0392015A4 (en) | Novel derivatives of physiologically active substance ml-236b and process for their preparation | |
ES8107191A1 (es) | Procedimiento para la preparacion de 2-(2-cloro-4-ciclopro- pil-fenil-imino)-imidazolidina | |
IL94548A0 (en) | Phenylacetic acid derivative,process for the preparation thereof and a pharmaceutical composition containing the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19981103 |