YU40625B - Process for producing n-cyano-n'-(2-(4-methyl-5-imidazolyl)-methylthio)-ethyl-n'-alkyl guanidines - Google Patents

Process for producing n-cyano-n'-(2-(4-methyl-5-imidazolyl)-methylthio)-ethyl-n'-alkyl guanidines

Info

Publication number
YU40625B
YU40625B YU2155/82A YU215582A YU40625B YU 40625 B YU40625 B YU 40625B YU 2155/82 A YU2155/82 A YU 2155/82A YU 215582 A YU215582 A YU 215582A YU 40625 B YU40625 B YU 40625B
Authority
YU
Yugoslavia
Prior art keywords
methylthio
imidazolyl
cyano
ethyl
methyl
Prior art date
Application number
YU2155/82A
Other versions
YU215582A (en
Inventor
R R Crenshaw
M G Luke
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/848,959 external-priority patent/US4112234A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of YU215582A publication Critical patent/YU215582A/en
Publication of YU40625B publication Critical patent/YU40625B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
YU2155/82A 1977-06-03 1982-09-27 Process for producing n-cyano-n'-(2-(4-methyl-5-imidazolyl)-methylthio)-ethyl-n'-alkyl guanidines YU40625B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80300977A 1977-06-03 1977-06-03
US82679677A 1977-08-22 1977-08-22
US05/848,959 US4112234A (en) 1977-08-22 1977-11-07 Imidazolylmethylthioethyl alkynyl guanidines

Publications (2)

Publication Number Publication Date
YU215582A YU215582A (en) 1983-02-28
YU40625B true YU40625B (en) 1986-02-28

Family

ID=27419995

Family Applications (4)

Application Number Title Priority Date Filing Date
YU01297/78A YU129778A (en) 1977-06-03 1978-05-31 Process for producing guanidine derivatives
YU530/79A YU41620B (en) 1977-06-03 1979-03-05 Process for obtaining thiocarbamide derivatives
YU2154/82A YU40624B (en) 1977-06-03 1982-09-27 Process for producing mercaptoethyl guanidine derivatives
YU2155/82A YU40625B (en) 1977-06-03 1982-09-27 Process for producing n-cyano-n'-(2-(4-methyl-5-imidazolyl)-methylthio)-ethyl-n'-alkyl guanidines

Family Applications Before (3)

Application Number Title Priority Date Filing Date
YU01297/78A YU129778A (en) 1977-06-03 1978-05-31 Process for producing guanidine derivatives
YU530/79A YU41620B (en) 1977-06-03 1979-03-05 Process for obtaining thiocarbamide derivatives
YU2154/82A YU40624B (en) 1977-06-03 1982-09-27 Process for producing mercaptoethyl guanidine derivatives

Country Status (26)

Country Link
JP (1) JPS543067A (en)
AR (2) AR222797A1 (en)
CA (1) CA1110251A (en)
CH (2) CH641167A5 (en)
CY (3) CY1231A (en)
DD (1) DD140038A5 (en)
DE (1) DE2824066A1 (en)
DK (1) DK243178A (en)
ES (3) ES470474A1 (en)
FI (1) FI69069C (en)
FR (2) FR2401143A1 (en)
GB (3) GB1598629A (en)
GR (1) GR73860B (en)
HK (3) HK38284A (en)
HU (1) HU186766B (en)
IE (1) IE47543B1 (en)
IL (1) IL54819A (en)
KE (1) KE3373A (en)
LU (1) LU79725A1 (en)
MY (3) MY8500452A (en)
NL (1) NL7805935A (en)
NO (3) NO152214C (en)
NZ (1) NZ187376A (en)
SE (3) SE443784B (en)
SG (1) SG8584G (en)
YU (4) YU129778A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS568352A (en) * 1979-07-03 1981-01-28 Shionogi & Co Ltd Aminoalkylvenzene derivative
US4339439A (en) * 1981-01-19 1982-07-13 Bristol-Myers Company Pharmaceutical methods and compositions
JPS57134318A (en) * 1981-02-12 1982-08-19 Nissan Motor Co Ltd Air mixing construction of air conditioner
JPS5848516U (en) * 1981-09-30 1983-04-01 日産車体株式会社 Vehicle air conditioner
JPS6018010U (en) * 1983-07-18 1985-02-07 日産自動車株式会社 Temperature adjustment mechanism of vehicle air conditioner
JPS60113211U (en) * 1984-01-06 1985-07-31 松下電器産業株式会社 Automotive air conditioner
ES2007948A6 (en) * 1988-07-06 1989-07-01 Vinas Lab Propargylguanidine derivatives and process for the preparation thereof.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024271A (en) * 1971-03-09 1977-05-17 Smith Kline & French Laboratories Limited Pharmacologically active guanidine compounds
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1531221A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for preparing guanidine derivatives
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines

Also Published As

Publication number Publication date
CY1231A (en) 1984-06-29
YU40624B (en) 1986-02-28
DD140038A5 (en) 1980-02-06
NO152214B (en) 1985-05-13
HK38284A (en) 1984-05-11
FR2401143A1 (en) 1979-03-23
HK38084A (en) 1984-05-11
NO151824B (en) 1985-03-04
CH644591A5 (en) 1984-08-15
YU129778A (en) 1983-02-28
AR222503A1 (en) 1981-05-29
IL54819A0 (en) 1978-07-31
CY1230A (en) 1984-06-29
CH641167A5 (en) 1984-02-15
SE8401491D0 (en) 1984-03-16
JPS543067A (en) 1979-01-11
YU41620B (en) 1987-12-31
YU53079A (en) 1983-09-30
NO151824C (en) 1985-06-12
FR2436138A1 (en) 1980-04-11
GR73860B (en) 1984-05-08
IL54819A (en) 1983-03-31
NL7805935A (en) 1978-12-05
FI69069B (en) 1985-08-30
SE7806525A (en) 1978-12-04
LU79725A1 (en) 1979-02-02
YU215482A (en) 1983-02-28
SE8401492D0 (en) 1984-03-16
DK243178A (en) 1978-12-04
DE2824066A1 (en) 1978-12-14
CA1110251A (en) 1981-10-06
NO791637L (en) 1978-12-05
NO152214C (en) 1985-08-28
GB1598630A (en) 1981-09-23
MY8500452A (en) 1985-12-31
IE781112L (en) 1978-12-03
ES478203A1 (en) 1979-06-01
FR2436138B1 (en) 1982-12-03
SE443784B (en) 1986-03-10
CY1229A (en) 1984-06-29
NO833255L (en) 1978-12-05
SE8401492L (en) 1984-03-16
HK38184A (en) 1984-05-11
SE8401491L (en) 1984-03-16
MY8500451A (en) 1985-12-31
FI781737A (en) 1978-12-04
GB1598629A (en) 1981-09-23
NZ187376A (en) 1981-05-29
NO781928L (en) 1978-12-05
IE47543B1 (en) 1984-04-18
ES470474A1 (en) 1979-09-01
YU215582A (en) 1983-02-28
JPS5639313B2 (en) 1981-09-11
KE3373A (en) 1984-03-23
SG8584G (en) 1985-02-08
FR2401143B1 (en) 1981-12-11
MY8500453A (en) 1985-12-31
SE7806525L (en) 1978-12-04
FI69069C (en) 1985-12-10
GB1598628A (en) 1981-09-23
AR222797A1 (en) 1981-06-30
HU186766B (en) 1985-09-30
ES478202A1 (en) 1979-06-01

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