NO152214C - ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE N-CYANO-N`- (2 - ((4-METHYL-5-IMIDAZOLYL) -METHYLTIO) ETHYL-N "-ALKNYLGUANIDINES - Google Patents

ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE N-CYANO-N`- (2 - ((4-METHYL-5-IMIDAZOLYL) -METHYLTIO) ETHYL-N "-ALKNYLGUANIDINES

Info

Publication number
NO152214C
NO152214C NO781928A NO781928A NO152214C NO 152214 C NO152214 C NO 152214C NO 781928 A NO781928 A NO 781928A NO 781928 A NO781928 A NO 781928A NO 152214 C NO152214 C NO 152214C
Authority
NO
Norway
Prior art keywords
alknylguanidines
methyltio
imidazolyl
cyano
ethyl
Prior art date
Application number
NO781928A
Other languages
Norwegian (no)
Other versions
NO152214B (en
NO781928L (en
Inventor
Ronnie Ray Crenshaw
George Michael Luke
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/848,959 external-priority patent/US4112234A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of NO781928L publication Critical patent/NO781928L/en
Publication of NO152214B publication Critical patent/NO152214B/en
Publication of NO152214C publication Critical patent/NO152214C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
NO781928A 1977-06-03 1978-06-02 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE N-CYANO-N`- (2 - ((4-METHYL-5-IMIDAZOLYL) -METHYLTIO) ETHYL-N "-ALKNYLGUANIDINES NO152214C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80300977A 1977-06-03 1977-06-03
US82679677A 1977-08-22 1977-08-22
US05/848,959 US4112234A (en) 1977-08-22 1977-11-07 Imidazolylmethylthioethyl alkynyl guanidines

Publications (3)

Publication Number Publication Date
NO781928L NO781928L (en) 1978-12-05
NO152214B NO152214B (en) 1985-05-13
NO152214C true NO152214C (en) 1985-08-28

Family

ID=27419995

Family Applications (3)

Application Number Title Priority Date Filing Date
NO781928A NO152214C (en) 1977-06-03 1978-06-02 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE N-CYANO-N`- (2 - ((4-METHYL-5-IMIDAZOLYL) -METHYLTIO) ETHYL-N "-ALKNYLGUANIDINES
NO791637A NO791637L (en) 1977-06-03 1979-05-16 INTERMEDIATE PRODUCTS FOR THE MANUFACTURE OF GUANIDINE DERIVATIVES
NO833255A NO151824C (en) 1977-06-03 1983-09-12 INTERMEDIATES FOR THE MANUFACTURE OF GUANIDINE DERIVATIVES

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO791637A NO791637L (en) 1977-06-03 1979-05-16 INTERMEDIATE PRODUCTS FOR THE MANUFACTURE OF GUANIDINE DERIVATIVES
NO833255A NO151824C (en) 1977-06-03 1983-09-12 INTERMEDIATES FOR THE MANUFACTURE OF GUANIDINE DERIVATIVES

Country Status (26)

Country Link
JP (1) JPS543067A (en)
AR (2) AR222797A1 (en)
CA (1) CA1110251A (en)
CH (2) CH641167A5 (en)
CY (3) CY1231A (en)
DD (1) DD140038A5 (en)
DE (1) DE2824066A1 (en)
DK (1) DK243178A (en)
ES (3) ES470474A1 (en)
FI (1) FI69069C (en)
FR (2) FR2401143A1 (en)
GB (3) GB1598629A (en)
GR (1) GR73860B (en)
HK (3) HK38284A (en)
HU (1) HU186766B (en)
IE (1) IE47543B1 (en)
IL (1) IL54819A (en)
KE (1) KE3373A (en)
LU (1) LU79725A1 (en)
MY (3) MY8500452A (en)
NL (1) NL7805935A (en)
NO (3) NO152214C (en)
NZ (1) NZ187376A (en)
SE (3) SE443784B (en)
SG (1) SG8584G (en)
YU (4) YU129778A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS568352A (en) * 1979-07-03 1981-01-28 Shionogi & Co Ltd Aminoalkylvenzene derivative
US4339439A (en) * 1981-01-19 1982-07-13 Bristol-Myers Company Pharmaceutical methods and compositions
JPS57134318A (en) * 1981-02-12 1982-08-19 Nissan Motor Co Ltd Air mixing construction of air conditioner
JPS5848516U (en) * 1981-09-30 1983-04-01 日産車体株式会社 Vehicle air conditioner
JPS6018010U (en) * 1983-07-18 1985-02-07 日産自動車株式会社 Temperature adjustment mechanism of vehicle air conditioner
JPS60113211U (en) * 1984-01-06 1985-07-31 松下電器産業株式会社 Automotive air conditioner
ES2007948A6 (en) * 1988-07-06 1989-07-01 Vinas Lab Propargylguanidine derivatives and process for the preparation thereof.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024271A (en) * 1971-03-09 1977-05-17 Smith Kline & French Laboratories Limited Pharmacologically active guanidine compounds
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1531221A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for preparing guanidine derivatives
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines

Also Published As

Publication number Publication date
CY1231A (en) 1984-06-29
YU40624B (en) 1986-02-28
DD140038A5 (en) 1980-02-06
NO152214B (en) 1985-05-13
HK38284A (en) 1984-05-11
FR2401143A1 (en) 1979-03-23
HK38084A (en) 1984-05-11
NO151824B (en) 1985-03-04
CH644591A5 (en) 1984-08-15
YU129778A (en) 1983-02-28
AR222503A1 (en) 1981-05-29
IL54819A0 (en) 1978-07-31
CY1230A (en) 1984-06-29
CH641167A5 (en) 1984-02-15
SE8401491D0 (en) 1984-03-16
JPS543067A (en) 1979-01-11
YU41620B (en) 1987-12-31
YU53079A (en) 1983-09-30
NO151824C (en) 1985-06-12
FR2436138A1 (en) 1980-04-11
GR73860B (en) 1984-05-08
IL54819A (en) 1983-03-31
NL7805935A (en) 1978-12-05
FI69069B (en) 1985-08-30
SE7806525A (en) 1978-12-04
LU79725A1 (en) 1979-02-02
YU215482A (en) 1983-02-28
SE8401492D0 (en) 1984-03-16
DK243178A (en) 1978-12-04
DE2824066A1 (en) 1978-12-14
CA1110251A (en) 1981-10-06
NO791637L (en) 1978-12-05
GB1598630A (en) 1981-09-23
MY8500452A (en) 1985-12-31
IE781112L (en) 1978-12-03
ES478203A1 (en) 1979-06-01
FR2436138B1 (en) 1982-12-03
SE443784B (en) 1986-03-10
CY1229A (en) 1984-06-29
NO833255L (en) 1978-12-05
SE8401492L (en) 1984-03-16
HK38184A (en) 1984-05-11
SE8401491L (en) 1984-03-16
MY8500451A (en) 1985-12-31
FI781737A (en) 1978-12-04
GB1598629A (en) 1981-09-23
NZ187376A (en) 1981-05-29
NO781928L (en) 1978-12-05
IE47543B1 (en) 1984-04-18
ES470474A1 (en) 1979-09-01
YU215582A (en) 1983-02-28
JPS5639313B2 (en) 1981-09-11
KE3373A (en) 1984-03-23
SG8584G (en) 1985-02-08
YU40625B (en) 1986-02-28
FR2401143B1 (en) 1981-12-11
MY8500453A (en) 1985-12-31
SE7806525L (en) 1978-12-04
FI69069C (en) 1985-12-10
GB1598628A (en) 1981-09-23
AR222797A1 (en) 1981-06-30
HU186766B (en) 1985-09-30
ES478202A1 (en) 1979-06-01

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