CZ302503B6 - Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace - Google Patents

Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace Download PDF

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Publication number
CZ302503B6
CZ302503B6 CZ20090835A CZ2009835A CZ302503B6 CZ 302503 B6 CZ302503 B6 CZ 302503B6 CZ 20090835 A CZ20090835 A CZ 20090835A CZ 2009835 A CZ2009835 A CZ 2009835A CZ 302503 B6 CZ302503 B6 CZ 302503B6
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CZ
Czechia
Prior art keywords
polysaccharide
aldehyde
water
process according
hyaluronan
Prior art date
Application number
CZ20090835A
Other languages
Czech (cs)
English (en)
Other versions
CZ2009835A3 (cs
Inventor
Buffa@Radovan
Kettou@Sofiane
Pospíšilová@Lucie
Huerta-Angeles@Gloria
Chládková@Drahomíra
Velebný@Vladimír
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Contipro C A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Contipro C A.S. filed Critical Contipro C A.S.
Priority to CZ20090835A priority Critical patent/CZ302503B6/cs
Priority to KR1020127017887A priority patent/KR101766693B1/ko
Priority to PL10812840T priority patent/PL2510016T3/pl
Priority to US13/512,484 priority patent/US9434791B2/en
Priority to EP10812840.6A priority patent/EP2510016B1/en
Priority to JP2012542356A priority patent/JP5886754B2/ja
Priority to RU2012125154/05A priority patent/RU2559447C2/ru
Priority to BR112012013955A priority patent/BR112012013955B1/pt
Priority to PCT/CZ2010/000129 priority patent/WO2011069475A2/en
Priority to HUE10812840A priority patent/HUE031497T2/en
Priority to DK10812840.6T priority patent/DK2510016T3/en
Publication of CZ2009835A3 publication Critical patent/CZ2009835A3/cs
Publication of CZ302503B6 publication Critical patent/CZ302503B6/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
CZ20090835A 2009-12-11 2009-12-11 Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace CZ302503B6 (cs)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CZ20090835A CZ302503B6 (cs) 2009-12-11 2009-12-11 Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace
KR1020127017887A KR101766693B1 (ko) 2009-12-11 2010-12-10 히알루론산의 산화된 유도체의 제조 방법 및 이의 변형 방법
PL10812840T PL2510016T3 (pl) 2009-12-11 2010-12-10 Sposób wytwarzania utlenionej pochodnej kwasu hialuronowego i sposób jej modyfikacji
US13/512,484 US9434791B2 (en) 2009-12-11 2010-12-10 Method of preparation of an oxidized derivative of hyaluronic acid and a method of modification thereof
EP10812840.6A EP2510016B1 (en) 2009-12-11 2010-12-10 A method of preparation of an oxidized derivative of hyaluronic acid and a method of modification thereof
JP2012542356A JP5886754B2 (ja) 2009-12-11 2010-12-10 ヒアルロン酸の酸化誘導体の調製方法及びその修飾方法
RU2012125154/05A RU2559447C2 (ru) 2009-12-11 2010-12-10 Способ получения окисленного производного гиалуроновой кислоты и способ его модификации
BR112012013955A BR112012013955B1 (pt) 2009-12-11 2010-12-10 método de preparação do derivado de ácido hialurônico seletivamente oxidado na posição (6) da parte glucosamina do polissacarídeo ao aldeído e método de modificação do derivado de ácido hialurônico
PCT/CZ2010/000129 WO2011069475A2 (en) 2009-12-11 2010-12-10 A method of preparation of an oxidized derivative of hyaluronic acid and a method of modification thereof
HUE10812840A HUE031497T2 (en) 2009-12-11 2010-12-10 A method for producing an oxidized hyaluronic acid derivative and a method for its modification
DK10812840.6T DK2510016T3 (en) 2009-12-11 2010-12-10 A process for preparing an oxidized derivative of hyaluronic acid and a process for modifying it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ20090835A CZ302503B6 (cs) 2009-12-11 2009-12-11 Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace

Publications (2)

Publication Number Publication Date
CZ2009835A3 CZ2009835A3 (cs) 2011-06-22
CZ302503B6 true CZ302503B6 (cs) 2011-06-22

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Family Applications (1)

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CZ20090835A CZ302503B6 (cs) 2009-12-11 2009-12-11 Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace

Country Status (11)

Country Link
US (1) US9434791B2 (enExample)
EP (1) EP2510016B1 (enExample)
JP (1) JP5886754B2 (enExample)
KR (1) KR101766693B1 (enExample)
BR (1) BR112012013955B1 (enExample)
CZ (1) CZ302503B6 (enExample)
DK (1) DK2510016T3 (enExample)
HU (1) HUE031497T2 (enExample)
PL (1) PL2510016T3 (enExample)
RU (1) RU2559447C2 (enExample)
WO (1) WO2011069475A2 (enExample)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ303722B6 (cs) * 2012-01-16 2013-04-03 Contipro Biotech S.R.O. Kyselina hyaluronová znacená tritiem, zpusob znacení kyseliny hyaluronové tritiem a její pouzití
CZ303879B6 (cs) * 2012-02-28 2013-06-05 Contipro Biotech S.R.O. Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
CZ304072B6 (cs) * 2011-04-26 2013-09-25 Contipro Biotech S.R.O. Amfoterní materiál na bázi sítované kyseliny hyaluronové, zpusob jeho prípravy, materiály obsahující aktivní cinidla uzavrené v síti hyaluronanu, zpusob jejich prípravy a jejich pouzití
CZ304266B6 (cs) * 2012-11-27 2014-02-05 Contipro Biotech S.R.O. Nekonečná vlákna na bázi hyaluronanu selektivně oxidovaného v poloze 6 N-acetyl-D-glukosaminové části, jejich příprava, použití, nitě, střiže, příze, textilie a způsob jejich úpravy
CZ304267B6 (cs) * 2012-11-27 2014-02-05 Contipro Biotech S.R.O. Fotoreaktivní derivát kyseliny hyaluronové, způsob jeho přípravy, 3D síťovaný derivát kyseliny hyaluronové, způsob jeho přípravy a použití
CZ304512B6 (cs) * 2012-08-08 2014-06-11 Contipro Biotech S.R.O. Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití
US9403918B2 (en) 2009-12-11 2016-08-02 Contipro Pharma A.S. Oxidized derivative of hyaluronic acid, a method of preparation thereof and a method of modification thereof
US9434791B2 (en) 2009-12-11 2016-09-06 Contipro Pharma A.S. Method of preparation of an oxidized derivative of hyaluronic acid and a method of modification thereof
US9999678B2 (en) 2012-11-27 2018-06-19 Contipro A.S. C6-C18-acylated derivative of hyaluronic acid and method of preparation thereof
US10023658B2 (en) 2014-03-11 2018-07-17 Contipro A.S. Conjugates of oligomer of hyaluronic acid or of a salt thereof, method of preparation thereof and use thereof
US10414832B2 (en) 2015-06-26 2019-09-17 Contipro A.S Derivatives of sulfated polysaccharides, method of preparation, modification and use thereof
US10617711B2 (en) 2014-06-30 2020-04-14 Contipro A.S. Antitumor composition based on hyaluronic acid and inorganic nanoparticles, method of preparation thereof and use thereof
US10618984B2 (en) 2016-06-27 2020-04-14 Contipro A.S. Unsaturated derivatives of polysaccharides, method of preparation thereof and use thereof
US10689464B2 (en) 2015-03-09 2020-06-23 Contipro A.S. Self-supporting, biodegradable film based on hydrophobized hyaluronic acid, method of preparation and use thereof
US10759878B2 (en) 2015-06-15 2020-09-01 Contipro A.S. Method of crosslinking of polysaccharides using photoremovable protecting groups

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PL221351B1 (pl) 2012-03-14 2016-03-31 Politechnika Warszawska Sposób otrzymywania nanocząstek polisacharydowych
ES2933127T3 (es) 2012-12-20 2023-02-01 Pfizer Procedimiento de glucoconjugación
EP3156044A1 (en) 2015-10-16 2017-04-19 Merz Pharma GmbH & Co. KGaA In situ cross-linkable polysaccharide compositions and uses thereof
US9751849B1 (en) 2016-12-06 2017-09-05 King Fahd University Of Petroleum And Minerals Method of producing a furanone compound
WO2019175036A1 (en) 2018-03-12 2019-09-19 Merz Pharma Gmbh & Co. Kgaa Porous biomaterials for tissue regeneration
CZ2018426A3 (cs) * 2018-08-23 2019-10-16 Contipro A.S. Chlorovaný derivát kyseliny hyaluronové, způsob jeho přípravy, kompozice, která jej obsahuje, a použití
CZ308064B6 (cs) 2018-08-23 2019-12-04 Contipro As Kompozice obsahující jodid a derivát kyseliny hyaluronové s oxidačním účinkem, způsob její přípravy a použití
EP3898703A1 (en) 2018-12-19 2021-10-27 Merz Pharma GmbH & Co. KGaA Aldehyde-modified hyaluronic acid, method for preparing same and applications thereof
IT202300004218A1 (it) 2023-03-07 2024-09-07 Delim Cosmetics & Pharma S R L Composizioni termoreversibili e mucoadesive
CN119161505A (zh) * 2024-09-27 2024-12-20 德州乡盛食品有限公司 一种抗菌性水溶性壳聚糖衍生物的制备方法及其应用

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