CY2291B1 - 1H-pyridoa3,4-buindole-4-carboxamide derivatives preparation and application thereof in therapeutics - Google Patents

1H-pyridoa3,4-buindole-4-carboxamide derivatives preparation and application thereof in therapeutics

Info

Publication number
CY2291B1
CY2291B1 CY0200050A CY0200050A CY2291B1 CY 2291 B1 CY2291 B1 CY 2291B1 CY 0200050 A CY0200050 A CY 0200050A CY 0200050 A CY0200050 A CY 0200050A CY 2291 B1 CY2291 B1 CY 2291B1
Authority
CY
Cyprus
Prior art keywords
pyridoa3
buindole
therapeutics
application
carboxamide derivatives
Prior art date
Application number
CY0200050A
Other languages
English (en)
Inventor
Yannick Evanno
Mireille Sevrin
Christian Maloizel
Odette Legalloudec
Pascal George
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of CY2291B1 publication Critical patent/CY2291B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CY0200050A 1996-10-08 2002-08-22 1H-pyridoa3,4-buindole-4-carboxamide derivatives preparation and application thereof in therapeutics CY2291B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9612229A FR2754262B1 (fr) 1996-10-08 1996-10-08 Derives de 1h-pyrido[3,4-b]indole-4-carboxamide, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
CY2291B1 true CY2291B1 (en) 2003-07-04

Family

ID=9496449

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0200050A CY2291B1 (en) 1996-10-08 2002-08-22 1H-pyridoa3,4-buindole-4-carboxamide derivatives preparation and application thereof in therapeutics

Country Status (33)

Country Link
US (1) US6075021A (et)
EP (1) EP0934319B1 (et)
JP (1) JP4227197B2 (et)
KR (1) KR100488095B1 (et)
CN (1) CN1089765C (et)
AR (1) AR009112A1 (et)
AT (1) ATE218567T1 (et)
AU (1) AU721102B2 (et)
BG (1) BG63751B1 (et)
BR (1) BR9711879A (et)
CA (1) CA2266376A1 (et)
CO (1) CO4910141A1 (et)
CY (1) CY2291B1 (et)
CZ (1) CZ298906B6 (et)
DE (1) DE69713124T2 (et)
DK (1) DK0934319T3 (et)
EE (1) EE03830B1 (et)
ES (1) ES2178008T3 (et)
FR (1) FR2754262B1 (et)
HK (1) HK1023338A1 (et)
HU (1) HUP9904623A3 (et)
IL (1) IL129018A0 (et)
NO (1) NO311938B1 (et)
NZ (1) NZ334708A (et)
PL (1) PL188244B1 (et)
PT (1) PT934319E (et)
RU (1) RU2180904C2 (et)
SK (1) SK282970B6 (et)
TR (1) TR199900712T2 (et)
TW (1) TW461889B (et)
UA (1) UA57037C2 (et)
WO (1) WO1998015552A1 (et)
ZA (1) ZA978970B (et)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2766823B1 (fr) * 1997-07-30 1999-10-08 Synthelabo Derives de 4-oxo-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide, leur preparation et leur application en therapeutique
FR2788696B1 (fr) * 1999-01-26 2004-03-05 Synthelabo Utilisation de derives de pyridazino [4,5-b] indole-1-acetamide pour la preparation de medicaments destines aux maladies du systeme nerveux central
FR2788776B1 (fr) * 1999-01-26 2001-02-23 Synthelabo Derives de 4-oxo-3, 5-dihydro-4h-pyridazino [4,5-b] indole-1 -carboxamide, leur preparation et leur application en therapeutique
FR2811897A1 (fr) * 2000-07-24 2002-01-25 Sanofi Synthelabo UTILISATION DE DERIVES DE PYRIDAZINO[4,5-b]INDOLE-1- ACETAMIDE POUR LA PREPARATION DE MEDICAMENTS DESTINES AU TRAITEMENT DES DYSFONCTIONNEMENTS DES RECEPTEURS DE TYPE PERIPHERIQUE AUX BENZODIAZEPINES
FR2811990A1 (fr) * 2000-07-24 2002-01-25 Sanofi Synthelabo DERIVES DE 1-(4-OXO-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-b]INDOLE-1 -CARBONYL)PIPERAZINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2833953B1 (fr) * 2001-12-21 2004-12-03 Sanofi Synthelabo DERIVES DE 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO [4,5-b]INDOLE-1-CARBOXAMIDE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2838124B1 (fr) 2002-04-03 2004-05-28 Sanofi Synthelabo Derives de 3-heteroaryl-3,5-dihydro-4-oxo-4h-pyridazino [4,5-b]indole-1-acetamide, leur preparation et leur application en therapeutique
PA8586801A1 (es) * 2002-10-31 2005-02-04 Pfizer Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso
BRPI0407052A (pt) * 2003-01-27 2006-01-17 Pfizer Inibidores da hiv-integrase, composições farmacêuticas, e métodos para sua utilização
BRPI0510319A (pt) * 2004-04-26 2007-10-16 Pfizer inibidores da enzima integrase de hiv
DE602005002746T2 (de) * 2004-04-26 2008-02-07 Pfizer Inc. Inhibitoren des hiv-integrase-enzyms
JP5483874B2 (ja) * 2005-05-05 2014-05-07 サノフィ−アベンティス・ユー・エス・エルエルシー 安定なナノ粒子処方物
BRPI0616657A2 (pt) * 2005-10-07 2011-06-28 Pfizer Prod Inc inibidores da enzima hiv integrase
UA95788C2 (en) 2005-12-15 2011-09-12 Ф. Хоффманн-Ля Рош Аг Fused pyrrole derivatives
WO2007143597A2 (en) * 2006-06-05 2007-12-13 Novartis Ag Organic compounds
CN1946120B (zh) * 2006-10-20 2010-05-12 华为技术有限公司 实现话单关联的方法及系统
KR100688448B1 (ko) * 2006-12-06 2007-03-02 (주)경진건축사사무소 건축물 내부 조적구조

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament

Also Published As

Publication number Publication date
CA2266376A1 (en) 1998-04-16
SK45199A3 (en) 2000-02-14
HK1023338A1 (en) 2000-09-08
NZ334708A (en) 2000-10-27
US6075021A (en) 2000-06-13
AU4559497A (en) 1998-05-05
CN1233248A (zh) 1999-10-27
EP0934319B1 (fr) 2002-06-05
BG103301A (en) 2000-05-31
AR009112A1 (es) 2000-03-08
EE03830B1 (et) 2002-08-15
JP4227197B2 (ja) 2009-02-18
FR2754262A1 (fr) 1998-04-10
CO4910141A1 (es) 2000-04-24
KR100488095B1 (ko) 2005-05-09
NO991624L (no) 1999-06-07
CN1089765C (zh) 2002-08-28
DK0934319T3 (da) 2002-09-30
PT934319E (pt) 2002-10-31
UA57037C2 (uk) 2003-06-16
FR2754262B1 (fr) 1998-10-30
BG63751B1 (bg) 2002-11-29
KR20000048992A (ko) 2000-07-25
IL129018A0 (en) 2000-02-17
RU2180904C2 (ru) 2002-03-27
WO1998015552A1 (fr) 1998-04-16
CZ298906B6 (cs) 2008-03-12
ATE218567T1 (de) 2002-06-15
NO991624D0 (no) 1999-04-06
DE69713124D1 (de) 2002-07-11
BR9711879A (pt) 1999-08-24
ZA978970B (en) 1998-04-20
TW461889B (en) 2001-11-01
NO311938B1 (no) 2002-02-18
ES2178008T3 (es) 2002-12-16
TR199900712T2 (xx) 1999-06-21
JP2001508403A (ja) 2001-06-26
EE9900155A (et) 1999-12-15
PL332643A1 (en) 1999-09-27
AU721102B2 (en) 2000-06-22
PL188244B1 (pl) 2005-01-31
CZ119399A3 (cs) 1999-07-14
HUP9904623A3 (en) 2001-03-28
HUP9904623A2 (hu) 2000-06-28
EP0934319A1 (fr) 1999-08-11
SK282970B6 (sk) 2003-01-09
DE69713124T2 (de) 2003-01-30

Similar Documents

Publication Publication Date Title
IL107132A0 (en) Piperidine derivatives,their preparation and their application in therapeutics
IL111148A0 (en) Imidazol-4- ylpiperidine derivatives, their preparation and their application in therapeutics
HUP9903691A3 (en) Pesticidal karbanilide derivatives, preparation and use thereof
IL120124A0 (en) Heteroaryl-oxazolidinones their preparation and use
HUP9801910A3 (en) Dolastatin derivatives, their preparation and use
SG79212A1 (en) Reactive dyes, their preparation and use
CY2291B1 (en) 1H-pyridoa3,4-buindole-4-carboxamide derivatives preparation and application thereof in therapeutics
ZA978089B (en) 3,4-diaryloxazolone derivatives, their methods of preparation, and their use in therapeutics.
ZA988921B (en) 3,4-diarylthiazolin-2-one or -2-thione derivatives their methods of preparation and their uses in therapeutics
ZA986786B (en) 4-oxo-3,5-dihydro-4H-pyridazino[4,5-B]indole-1-acetamide-derivatives their preparation and their application in therapeutics
IL118644A (en) N-¬(1,4-diazabicyclo¬2.2.2¾oct-2-YL)methyl¾benzamide derivatives their preparation and their application in therapeutics
ZA989664B (en) 3-substituted tetrahydropyrimidinone derivatives, their preparation and use.
HUP9904091A3 (en) N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics
ZA972894B (en) Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics.
ZA977767B (en) Benzylamine derivatives, their preparation and their application in therapeutics.
ZA898480B (en) Phenyloxypropanolamine derivatives,their preparation and their application in therapeutics
IL133536A0 (en) 6-pyrrolidin-2-ylpyridine derivatives, their preparation and application in therapy
AU1858692A (en) 2-piperidinylpyrimidine-4-carboxamide derivatives, their preparation and their use in therapeutics
SG81913A1 (en) Reactive dyes, their preparation and use
ZA9710515B (en) N-(imidazolybutyl) benezenesulphonamide derivatives, their preparation and their application in therapeutics.
AU3448097A (en) 1-oxo-1,2-dihydroisoquinoline-4-propanamide derivatives and their application in therapeutics
GB2324090B (en) 5,6-O-alkylidene glucono-1(4)-lactones and derivatives thereof,their preparation and use
ZA967558B (en) Alpha-phenylpiperidine-1-propanol derivatives their preparation and their application in therapeutics
ZA982358B (en) Benzenesulphonamide derivatives their preparation and their application in therapeutics
SI0934319T1 (en) 1H-PYRIDO(3,4-b)INDOLE-4-CARBOXAMIDE DERIVATIVES, PREPARATION AND APPLICATION THEREOF IN THERAPEUTICS