ZA972894B - Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics. - Google Patents
Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics.Info
- Publication number
- ZA972894B ZA972894B ZA9702894A ZA972894A ZA972894B ZA 972894 B ZA972894 B ZA 972894B ZA 9702894 A ZA9702894 A ZA 9702894A ZA 972894 A ZA972894 A ZA 972894A ZA 972894 B ZA972894 B ZA 972894B
- Authority
- ZA
- South Africa
- Prior art keywords
- therapeutics
- processes
- preparation
- diarylmethylidenefuran derivatives
- diarylmethylidenefuran
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9604236A FR2747123B1 (en) | 1996-04-04 | 1996-04-04 | NOVEL DIARYLMETHYLIDENE TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THERAPEUTIC USES |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA972894B true ZA972894B (en) | 1997-11-04 |
Family
ID=9490907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9702894A ZA972894B (en) | 1996-04-04 | 1997-04-04 | Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics. |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP0891345B1 (en) |
JP (1) | JP2000508638A (en) |
KR (1) | KR20000005146A (en) |
CN (1) | CN1215396A (en) |
AR (1) | AR006539A1 (en) |
AT (1) | ATE204268T1 (en) |
AU (1) | AU717146B2 (en) |
BG (1) | BG62808B1 (en) |
BR (1) | BR9708510A (en) |
CA (1) | CA2248949A1 (en) |
CZ (1) | CZ318898A3 (en) |
DE (1) | DE69706157T2 (en) |
DK (1) | DK0891345T3 (en) |
EE (1) | EE03687B1 (en) |
ES (1) | ES2162678T3 (en) |
FR (2) | FR2747123B1 (en) |
GE (1) | GEP20032924B (en) |
IL (1) | IL126105A (en) |
NO (1) | NO984624L (en) |
NZ (1) | NZ331672A (en) |
PL (1) | PL329213A1 (en) |
PT (1) | PT891345E (en) |
RU (1) | RU2189979C2 (en) |
SI (1) | SI0891345T1 (en) |
SK (1) | SK283292B6 (en) |
TW (1) | TW353660B (en) |
WO (1) | WO1997037984A1 (en) |
ZA (1) | ZA972894B (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6180651B1 (en) * | 1996-04-04 | 2001-01-30 | Bristol-Myers Squibb | Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics |
AU6818298A (en) * | 1997-04-02 | 1998-10-22 | Merck Frosst Canada & Co. | Alpha-methylene gamma lactones as selective cyclooxygenase-2 inhibitors |
FR2775477B1 (en) * | 1998-02-27 | 2000-05-19 | Union Pharma Scient Appl | NOVEL HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES |
CN1106392C (en) * | 2000-10-24 | 2003-04-23 | 中国科学院上海有机化学研究所 | Butenolide containing no substituent at beta position and its synthesis process |
CN102579427A (en) * | 2002-11-05 | 2012-07-18 | 马格纳化学国际实验室公司 | Synthetic lactone formulations and method of use |
CA2524568C (en) * | 2003-03-31 | 2012-07-17 | Council Of Scientific & Industrial Research | Mercapto-phenyl-naphthyl-methane derivatives and preparation thereof |
EP1534305B9 (en) | 2003-05-07 | 2007-03-07 | Osteologix A/S | Treating cartilage / bone conditions with water-soluble strontium salts |
US8779168B2 (en) * | 2010-12-16 | 2014-07-15 | Transitions Optical, Inc. | Lactone compounds and materials made therefrom |
CA3209491A1 (en) | 2021-03-15 | 2022-09-22 | Saul Yedgar | Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2297592A1 (en) * | 1993-01-15 | 1994-07-21 | G.D. Searle & Co. | Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
US5585504A (en) * | 1994-09-16 | 1996-12-17 | Merck & Co., Inc. | Process of making cox-2 inhibitors having a lactone bridge |
-
1996
- 1996-04-04 FR FR9604236A patent/FR2747123B1/en not_active Expired - Fee Related
- 1996-06-26 FR FR9607922A patent/FR2747124B1/en not_active Expired - Lifetime
-
1997
- 1997-03-24 TW TW086103701A patent/TW353660B/en active
- 1997-04-03 NZ NZ331672A patent/NZ331672A/en unknown
- 1997-04-03 PL PL97329213A patent/PL329213A1/en unknown
- 1997-04-03 BR BR9708510A patent/BR9708510A/en not_active IP Right Cessation
- 1997-04-03 EP EP97919476A patent/EP0891345B1/en not_active Expired - Lifetime
- 1997-04-03 CN CN97193543A patent/CN1215396A/en active Pending
- 1997-04-03 EE EE9800333A patent/EE03687B1/en unknown
- 1997-04-03 AU AU23933/97A patent/AU717146B2/en not_active Ceased
- 1997-04-03 KR KR1019980707808A patent/KR20000005146A/en not_active Application Discontinuation
- 1997-04-03 JP JP9535910A patent/JP2000508638A/en active Pending
- 1997-04-03 AT AT97919476T patent/ATE204268T1/en active
- 1997-04-03 RU RU98119887/04A patent/RU2189979C2/en not_active IP Right Cessation
- 1997-04-03 CA CA002248949A patent/CA2248949A1/en not_active Abandoned
- 1997-04-03 ES ES97919476T patent/ES2162678T3/en not_active Expired - Lifetime
- 1997-04-03 IL IL12610597A patent/IL126105A/en not_active IP Right Cessation
- 1997-04-03 SK SK1375-98A patent/SK283292B6/en not_active IP Right Cessation
- 1997-04-03 PT PT97919476T patent/PT891345E/en unknown
- 1997-04-03 DK DK97919476T patent/DK0891345T3/en active
- 1997-04-03 GE GEAP19974555A patent/GEP20032924B/en unknown
- 1997-04-03 DE DE69706157T patent/DE69706157T2/en not_active Expired - Lifetime
- 1997-04-03 CZ CZ983188A patent/CZ318898A3/en unknown
- 1997-04-03 WO PCT/FR1997/000602 patent/WO1997037984A1/en not_active Application Discontinuation
- 1997-04-03 SI SI9730222T patent/SI0891345T1/en unknown
- 1997-04-04 ZA ZA9702894A patent/ZA972894B/en unknown
- 1997-04-04 AR ARP970101359A patent/AR006539A1/en not_active Application Discontinuation
-
1998
- 1998-09-16 BG BG102771A patent/BG62808B1/en unknown
- 1998-10-02 NO NO984624A patent/NO984624L/en not_active Application Discontinuation
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