IL126105A0 - Novel furan diarylmethylidene derivatives method for their preparation and therapeutical uses thereof - Google Patents
Novel furan diarylmethylidene derivatives method for their preparation and therapeutical uses thereofInfo
- Publication number
- IL126105A0 IL126105A0 IL12610597A IL12610597A IL126105A0 IL 126105 A0 IL126105 A0 IL 126105A0 IL 12610597 A IL12610597 A IL 12610597A IL 12610597 A IL12610597 A IL 12610597A IL 126105 A0 IL126105 A0 IL 126105A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- therapeutical uses
- derivatives method
- novel furan
- diarylmethylidene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9604236A FR2747123B1 (en) | 1996-04-04 | 1996-04-04 | NOVEL DIARYLMETHYLIDENE TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THERAPEUTIC USES |
| FR9607922A FR2747124B1 (en) | 1996-04-04 | 1996-06-26 | NOVEL FURANIC DIARYLMETHYLIDENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES |
| PCT/FR1997/000602 WO1997037984A1 (en) | 1996-04-04 | 1997-04-03 | Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL126105A0 true IL126105A0 (en) | 1999-05-09 |
| IL126105A IL126105A (en) | 2001-08-26 |
Family
ID=9490907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12610597A IL126105A (en) | 1996-04-04 | 1997-04-03 | Furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0891345B1 (en) |
| JP (1) | JP2000508638A (en) |
| KR (1) | KR20000005146A (en) |
| CN (1) | CN1215396A (en) |
| AR (1) | AR006539A1 (en) |
| AT (1) | ATE204268T1 (en) |
| AU (1) | AU717146B2 (en) |
| BG (1) | BG62808B1 (en) |
| BR (1) | BR9708510A (en) |
| CA (1) | CA2248949A1 (en) |
| CZ (1) | CZ318898A3 (en) |
| DE (1) | DE69706157T2 (en) |
| DK (1) | DK0891345T3 (en) |
| EE (1) | EE03687B1 (en) |
| ES (1) | ES2162678T3 (en) |
| FR (2) | FR2747123B1 (en) |
| GE (1) | GEP20032924B (en) |
| IL (1) | IL126105A (en) |
| NO (1) | NO984624L (en) |
| NZ (1) | NZ331672A (en) |
| PL (1) | PL329213A1 (en) |
| PT (1) | PT891345E (en) |
| RU (1) | RU2189979C2 (en) |
| SI (1) | SI0891345T1 (en) |
| SK (1) | SK283292B6 (en) |
| TW (1) | TW353660B (en) |
| WO (1) | WO1997037984A1 (en) |
| ZA (1) | ZA972894B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6180651B1 (en) * | 1996-04-04 | 2001-01-30 | Bristol-Myers Squibb | Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics |
| EP0971910A1 (en) * | 1997-04-02 | 2000-01-19 | Merck Frosst Canada & Co. | Alpha-methylene gamma lactones as selective cyclooxygenase-2 inhibitors |
| FR2775477B1 (en) * | 1998-02-27 | 2000-05-19 | Union Pharma Scient Appl | NOVEL HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES |
| CN1106392C (en) * | 2000-10-24 | 2003-04-23 | 中国科学院上海有机化学研究所 | Butenolide containing no substituent at beta position and its synthesis process |
| WO2004041217A2 (en) * | 2002-11-05 | 2004-05-21 | Magnachem International Laboratories, Inc. | Synthetic lactone formulations and method of use |
| EP1692101B1 (en) * | 2003-03-31 | 2011-07-06 | Council of Scientific and Industrial Research | Mercapto-phenyl-naphthyl-methane derivatives and preparation thereof |
| PL1745791T3 (en) | 2003-05-07 | 2013-11-29 | Osteologix As | Treating cartilage/bone conditions with water-soluble strontium salts |
| US8779168B2 (en) * | 2010-12-16 | 2014-07-15 | Transitions Optical, Inc. | Lactone compounds and materials made therefrom |
| IL305573A (en) | 2021-03-15 | 2023-10-01 | Saul Yedgar | HYALURONIC ACID-CONJUGATED DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE IN COMBINATION WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) FOR TREATING OR ALLEVIATING INFLAMMATORY DISEASES |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0679157T3 (en) * | 1993-01-15 | 1998-07-27 | Searle & Co | Novel 3,4-diarylthiophenes and analogs thereof for use as anti-inflammatory agents |
| US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5585504A (en) * | 1994-09-16 | 1996-12-17 | Merck & Co., Inc. | Process of making cox-2 inhibitors having a lactone bridge |
-
1996
- 1996-04-04 FR FR9604236A patent/FR2747123B1/en not_active Expired - Fee Related
- 1996-06-26 FR FR9607922A patent/FR2747124B1/en not_active Expired - Lifetime
-
1997
- 1997-03-24 TW TW086103701A patent/TW353660B/en active
- 1997-04-03 EE EE9800333A patent/EE03687B1/en unknown
- 1997-04-03 DE DE69706157T patent/DE69706157T2/en not_active Expired - Lifetime
- 1997-04-03 KR KR1019980707808A patent/KR20000005146A/en not_active Application Discontinuation
- 1997-04-03 ES ES97919476T patent/ES2162678T3/en not_active Expired - Lifetime
- 1997-04-03 AU AU23933/97A patent/AU717146B2/en not_active Ceased
- 1997-04-03 SI SI9730222T patent/SI0891345T1/en unknown
- 1997-04-03 RU RU98119887/04A patent/RU2189979C2/en not_active IP Right Cessation
- 1997-04-03 PL PL97329213A patent/PL329213A1/en unknown
- 1997-04-03 CN CN97193543A patent/CN1215396A/en active Pending
- 1997-04-03 CZ CZ983188A patent/CZ318898A3/en unknown
- 1997-04-03 CA CA002248949A patent/CA2248949A1/en not_active Abandoned
- 1997-04-03 WO PCT/FR1997/000602 patent/WO1997037984A1/en not_active Application Discontinuation
- 1997-04-03 DK DK97919476T patent/DK0891345T3/en active
- 1997-04-03 SK SK1375-98A patent/SK283292B6/en not_active IP Right Cessation
- 1997-04-03 JP JP9535910A patent/JP2000508638A/en active Pending
- 1997-04-03 AT AT97919476T patent/ATE204268T1/en active
- 1997-04-03 PT PT97919476T patent/PT891345E/en unknown
- 1997-04-03 NZ NZ331672A patent/NZ331672A/en unknown
- 1997-04-03 IL IL12610597A patent/IL126105A/en not_active IP Right Cessation
- 1997-04-03 BR BR9708510A patent/BR9708510A/en not_active IP Right Cessation
- 1997-04-03 GE GEAP19974555A patent/GEP20032924B/en unknown
- 1997-04-03 EP EP97919476A patent/EP0891345B1/en not_active Expired - Lifetime
- 1997-04-04 AR ARP970101359A patent/AR006539A1/en not_active Application Discontinuation
- 1997-04-04 ZA ZA9702894A patent/ZA972894B/en unknown
-
1998
- 1998-09-16 BG BG102771A patent/BG62808B1/en unknown
- 1998-10-02 NO NO984624A patent/NO984624L/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |