AU2393397A - Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof - Google Patents

Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof

Info

Publication number
AU2393397A
AU2393397A AU23933/97A AU2393397A AU2393397A AU 2393397 A AU2393397 A AU 2393397A AU 23933/97 A AU23933/97 A AU 23933/97A AU 2393397 A AU2393397 A AU 2393397A AU 2393397 A AU2393397 A AU 2393397A
Authority
AU
Australia
Prior art keywords
preparation
therapeutical uses
novel furan
diarylmethylidene
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU23933/97A
Other versions
AU717146B2 (en
Inventor
Eric Nicolai
Jean-Marie Teulon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UPSA SAS
Original Assignee
UNION PHARMA SCIENT APPL
UPSA SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNION PHARMA SCIENT APPL, UPSA SAS filed Critical UNION PHARMA SCIENT APPL
Publication of AU2393397A publication Critical patent/AU2393397A/en
Application granted granted Critical
Publication of AU717146B2 publication Critical patent/AU717146B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58—One oxygen atom, e.g. butenolide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
AU23933/97A 1996-04-04 1997-04-03 Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof Ceased AU717146B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR96/04236 1996-04-04
FR9604236A FR2747123B1 (en) 1996-04-04 1996-04-04 NOVEL DIARYLMETHYLIDENE TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THERAPEUTIC USES
FR9607922A FR2747124B1 (en) 1996-04-04 1996-06-26 NOVEL FURANIC DIARYLMETHYLIDENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES
FR96/07922 1996-06-26
PCT/FR1997/000602 WO1997037984A1 (en) 1996-04-04 1997-04-03 Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof

Publications (2)

Publication Number Publication Date
AU2393397A true AU2393397A (en) 1997-10-29
AU717146B2 AU717146B2 (en) 2000-03-16

Family

ID=9490907

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23933/97A Ceased AU717146B2 (en) 1996-04-04 1997-04-03 Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof

Country Status (28)

Country Link
EP (1) EP0891345B1 (en)
JP (1) JP2000508638A (en)
KR (1) KR20000005146A (en)
CN (1) CN1215396A (en)
AR (1) AR006539A1 (en)
AT (1) ATE204268T1 (en)
AU (1) AU717146B2 (en)
BG (1) BG62808B1 (en)
BR (1) BR9708510A (en)
CA (1) CA2248949A1 (en)
CZ (1) CZ318898A3 (en)
DE (1) DE69706157T2 (en)
DK (1) DK0891345T3 (en)
EE (1) EE03687B1 (en)
ES (1) ES2162678T3 (en)
FR (2) FR2747123B1 (en)
GE (1) GEP20032924B (en)
IL (1) IL126105A (en)
NO (1) NO984624L (en)
NZ (1) NZ331672A (en)
PL (1) PL329213A1 (en)
PT (1) PT891345E (en)
RU (1) RU2189979C2 (en)
SI (1) SI0891345T1 (en)
SK (1) SK283292B6 (en)
TW (1) TW353660B (en)
WO (1) WO1997037984A1 (en)
ZA (1) ZA972894B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180651B1 (en) * 1996-04-04 2001-01-30 Bristol-Myers Squibb Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
EP0971910A1 (en) * 1997-04-02 2000-01-19 Merck Frosst Canada & Co. Alpha-methylene gamma lactones as selective cyclooxygenase-2 inhibitors
FR2775477B1 (en) * 1998-02-27 2000-05-19 Union Pharma Scient Appl NOVEL HETEROCYCLIC DIARYLMETHYLENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES
CN1106392C (en) * 2000-10-24 2003-04-23 中国科学院上海有机化学研究所 Butenolide containing no substituent at beta position and its synthesis process
WO2004041217A2 (en) * 2002-11-05 2004-05-21 Magnachem International Laboratories, Inc. Synthetic lactone formulations and method of use
EP1692101B1 (en) * 2003-03-31 2011-07-06 Council of Scientific and Industrial Research Mercapto-phenyl-naphthyl-methane derivatives and preparation thereof
PL1745791T3 (en) 2003-05-07 2013-11-29 Osteologix As Treating cartilage/bone conditions with water-soluble strontium salts
US8779168B2 (en) * 2010-12-16 2014-07-15 Transitions Optical, Inc. Lactone compounds and materials made therefrom
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar HYALURONIC ACID-CONJUGATED DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE IN COMBINATION WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) FOR TREATING OR ALLEVIATING INFLAMMATORY DISEASES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0679157T3 (en) * 1993-01-15 1998-07-27 Searle & Co Novel 3,4-diarylthiophenes and analogs thereof for use as anti-inflammatory agents
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5585504A (en) * 1994-09-16 1996-12-17 Merck & Co., Inc. Process of making cox-2 inhibitors having a lactone bridge

Also Published As

Publication number Publication date
JP2000508638A (en) 2000-07-11
FR2747124B1 (en) 1998-06-26
NO984624D0 (en) 1998-10-02
CN1215396A (en) 1999-04-28
EE9800333A (en) 1999-04-15
IL126105A0 (en) 1999-05-09
KR20000005146A (en) 2000-01-25
ES2162678T3 (en) 2002-01-01
CA2248949A1 (en) 1997-10-16
SK283292B6 (en) 2003-05-02
GEP20032924B (en) 2003-03-25
BR9708510A (en) 1999-08-03
SI0891345T1 (en) 2002-02-28
ZA972894B (en) 1997-11-04
TW353660B (en) 1999-03-01
NO984624L (en) 1998-11-30
PT891345E (en) 2002-02-28
ATE204268T1 (en) 2001-09-15
BG62808B1 (en) 2000-08-31
EE03687B1 (en) 2002-04-15
NZ331672A (en) 2000-02-28
CZ318898A3 (en) 1999-01-13
AU717146B2 (en) 2000-03-16
FR2747124A1 (en) 1997-10-10
EP0891345B1 (en) 2001-08-16
EP0891345A1 (en) 1999-01-20
FR2747123B1 (en) 1998-06-26
BG102771A (en) 1999-06-30
WO1997037984A1 (en) 1997-10-16
DE69706157D1 (en) 2001-09-20
RU2189979C2 (en) 2002-09-27
IL126105A (en) 2001-08-26
DK0891345T3 (en) 2001-12-03
PL329213A1 (en) 1999-03-15
FR2747123A1 (en) 1997-10-10
SK137598A3 (en) 1999-02-11
DE69706157T2 (en) 2002-04-11
AR006539A1 (en) 1999-09-08

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired