CY1121841T1 - Τοπικη αντιμυκητιασικη συνθεση για τη θεραπεια της ονυχομυκητιασης - Google Patents
Τοπικη αντιμυκητιασικη συνθεση για τη θεραπεια της ονυχομυκητιασηςInfo
- Publication number
- CY1121841T1 CY1121841T1 CY20191100804T CY191100804T CY1121841T1 CY 1121841 T1 CY1121841 T1 CY 1121841T1 CY 20191100804 T CY20191100804 T CY 20191100804T CY 191100804 T CY191100804 T CY 191100804T CY 1121841 T1 CY1121841 T1 CY 1121841T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- onychomycitis
- antifungal composition
- topical antifungal
- relates
- Prior art date
Links
- 239000012871 anti-fungal composition Substances 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- 208000010195 Onychomycosis Diseases 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940054190 hydroxypropyl chitosan Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 abstract 1
- 229960002722 terbinafine Drugs 0.000 abstract 1
- 201000005882 tinea unguium Diseases 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Η παρούσα εφεύρεση αφορά μια λάκα νυχιών που αποτελείται ουσιαστικά από τερβιναφίνη ως αντιμυκητιακό παράγοντα, υδροξυπροπυλική χιτοζάνη ως παράγοντα σχηματισμού υμενίου, νερό και μια κατώτερη αλκανόλη ως διαλύτες. Η εφεύρεση αφορά επίσης μια μέθοδο για τη θεραπεία της ονυχομυκητίασης μέσω τοπικής χορήγησης, όπως μια λάκα νυχιών, σε έναν ασθενή που χρήζει τέτοιας θεραπείας.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361761953P | 2013-02-07 | 2013-02-07 | |
US201361781560P | 2013-03-14 | 2013-03-14 | |
PCT/EP2014/051288 WO2014122024A1 (en) | 2013-02-07 | 2014-01-23 | Topical antifungal composition for treating onychomycosis |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1121841T1 true CY1121841T1 (el) | 2020-07-31 |
Family
ID=50029007
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20191100804T CY1121841T1 (el) | 2013-02-07 | 2019-07-29 | Τοπικη αντιμυκητιασικη συνθεση για τη θεραπεια της ονυχομυκητιασης |
Country Status (35)
Country | Link |
---|---|
US (3) | US8697753B1 (el) |
EP (1) | EP2953621B1 (el) |
JP (1) | JP6420258B2 (el) |
KR (1) | KR102200788B1 (el) |
CN (1) | CN105050592B (el) |
AU (1) | AU2014214166B2 (el) |
BR (1) | BR112015018798B1 (el) |
CA (1) | CA2900127C (el) |
CL (1) | CL2015002191A1 (el) |
CR (1) | CR20150377A (el) |
CY (1) | CY1121841T1 (el) |
DK (1) | DK2953621T3 (el) |
EA (1) | EA036061B1 (el) |
EC (1) | ECSP15033898A (el) |
ES (1) | ES2729373T3 (el) |
HK (1) | HK1212904A1 (el) |
HR (1) | HRP20191243T1 (el) |
HU (1) | HUE045000T2 (el) |
IL (1) | IL240334B (el) |
LT (1) | LT2953621T (el) |
ME (1) | ME03507B (el) |
MX (1) | MX361880B (el) |
NZ (1) | NZ709668A (el) |
PE (1) | PE20151300A1 (el) |
PH (1) | PH12015501739B1 (el) |
PL (1) | PL2953621T3 (el) |
PT (1) | PT2953621T (el) |
RS (1) | RS58990B1 (el) |
SG (1) | SG11201505275YA (el) |
SI (1) | SI2953621T1 (el) |
TN (1) | TN2015000316A1 (el) |
TW (1) | TWI658839B (el) |
UY (1) | UY35307A (el) |
WO (1) | WO2014122024A1 (el) |
ZA (1) | ZA201504880B (el) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8697753B1 (en) * | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
KR101580077B1 (ko) * | 2015-03-28 | 2015-12-24 | 한국콜마주식회사 | 시크로피록스 함유 네일락카 조성물 |
GB201605127D0 (en) * | 2016-03-25 | 2016-05-11 | Blueberry Therapeutics Ltd | Composition and methods of treatment |
DE102019003486B4 (de) * | 2019-05-17 | 2021-03-18 | L/N Health And Beauty Aps | Zusammensetzungen zur Behandlung der Onychomykose |
WO2021127107A1 (en) * | 2019-12-20 | 2021-06-24 | Glaxosmithkline Consumer Healthcare Holdings (Us) Llc | Topical pharmaceutical compositions for treating onychomycosis |
Family Cites Families (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3883545A (en) | 1968-08-31 | 1975-05-13 | Hoechst Ag | Certain 1-hydroxy-2-pyridones |
AT354187B (de) | 1976-11-22 | 1979-12-27 | Hoffmann La Roche | Fungizides mittel |
DE19975055I1 (de) | 1979-08-22 | 2000-01-27 | Novartis Ag | Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwending als Arzneimittel |
DE3045914A1 (de) | 1980-12-05 | 1982-07-22 | Bayer Ag, 5090 Leverkusen | Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern |
DE3045915A1 (de) | 1980-12-05 | 1982-07-08 | Bayer Ag, 5090 Leverkusen | Antimykotische mittel mit hoher wirkstoff-freisetzung in form von elastischen fluessig-pflastern |
DE3245784A1 (de) | 1982-12-10 | 1984-06-14 | Wella Ag, 6100 Darmstadt | Kosmetisches mittel auf der basis von quaternaeren chitosanderivaten, neue quaternaere chitosanderivate sowie verfahren zu ihrer herstellung |
DE3502833A1 (de) | 1985-01-29 | 1986-07-31 | Wella Ag, 6100 Darmstadt | Kosmetische mittel auf der basis von quaternaeren chitosanderivaten, neue quaternaere hydroxyethyl-substituierte chitosanderivate sowie verfahren zu ihrer herstellung |
DE3513277A1 (de) | 1985-04-13 | 1986-10-23 | Wella Ag, 6100 Darmstadt | Kosmetische mittel auf der basis von quaternaeren hydroxyalkyl-substituierten chitosanderivaten |
EP0247142B1 (en) | 1985-11-04 | 1993-01-07 | Owen/Galderma Laboratories Inc. | Film-forming, pharmaceutical vehicles for application of medicaments to nails, pharmaceutical compositions based on those vehicles, and methods of using same |
DE3541305A1 (de) | 1985-11-22 | 1987-05-27 | Wella Ag | Kosmetische mittel auf der basis von n-hydroxypropylchitosanen, neue n-hydroxypropyl-chitosane sowie verfahren zu ihrer herstellung |
DE3544983A1 (de) | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
DE3545929A1 (de) | 1985-12-23 | 1987-06-25 | Ceag Licht & Strom | Gehaeuse |
SE460713B (sv) | 1986-04-22 | 1989-11-13 | Atlas Copco Ab | Hydrauliskt momentimpulsverk |
US4946870A (en) | 1986-06-06 | 1990-08-07 | Union Carbide Chemicals And Plastics Company Inc. | Delivery systems for pharmaceutical or therapeutic actives |
DE3703760A1 (de) | 1987-02-07 | 1988-08-18 | Wella Ag | Kosmetisches mittel auf der basis von n-hydroxypropylisopropyletherchitosanen, sowie neue n-hydroxypropylisopropyletherderivate des chitosans |
HU200914B (en) | 1987-03-09 | 1990-09-28 | Horvath Gyoengyi Lengyelne | Process for producing new medical dosage unit suitable for local treatment of fungus infection of nails |
DE3720147A1 (de) | 1987-06-16 | 1988-12-29 | Hoechst Ag | Antimykotisch wirksamer nagellack sowie verfahren zu dessen herstellung |
DE3723811A1 (de) | 1987-07-18 | 1989-01-26 | Wella Ag | Nagellack auf der basis von o-benzyl-n-hydroxyalkylchitosanen sowie neue o-benzyl-n-hydroxyalkylderivate des chitosans |
CA2008775C (en) | 1989-02-24 | 1998-12-22 | Alberto Ferro | Nail lacquer |
FR2673537B1 (fr) | 1991-03-08 | 1993-06-11 | Oreal | Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes. |
DE4108664C2 (de) | 1991-03-16 | 1995-03-09 | Scheller Cosmetics Gmbh Dr | Nagellack und Verwendung desselben |
HU223343B1 (hu) | 1991-05-20 | 2004-06-28 | Novartis Ag. | Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására |
US6005001A (en) | 1991-05-20 | 1999-12-21 | Novartis Ag (Formerly Sandoz Ag) | Pharmaceutical composition |
HU219480B (hu) | 1991-05-23 | 2001-04-28 | Novartis Ag. | Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására |
DE4212105A1 (de) | 1992-04-10 | 1993-10-14 | Roehm Pharma Gmbh | Nagellack zur Behandlung von Onychomykosen |
JPH05339152A (ja) | 1992-06-09 | 1993-12-21 | Nippon Soda Co Ltd | 皮膚病変局所投与薬剤含有キトサン誘導体フィルム剤 |
JPH06211651A (ja) | 1993-01-12 | 1994-08-02 | Hisamitsu Pharmaceut Co Inc | 爪白癬治療用組成物 |
DE19518262A1 (de) | 1995-05-18 | 1996-11-21 | Hoechst Ag | Die Verwendung von Glyceryltriacetat zur Behandlung von Onychomykosen |
US5391367A (en) | 1993-07-28 | 1995-02-21 | Pfizer Inc. | Antifungal nail solution |
US5487776A (en) | 1994-03-17 | 1996-01-30 | Nimni; Marcel | Anti-fungal nail lacquer and method therefor |
WO1996011710A1 (fr) | 1994-10-13 | 1996-04-25 | Hisamitsu Pharmaceutical Co., Inc. | Preparation externe pour onychomycose |
JP2951725B2 (ja) | 1994-10-13 | 1999-09-20 | 久光製薬株式会社 | 爪白癬用外用組成物 |
US5696164A (en) | 1994-12-22 | 1997-12-09 | Johnson & Johnson Consumer Products, Inc. | Antifungal treatment of nails |
DE19503423A1 (de) | 1995-02-03 | 1996-08-08 | Beiersdorf Ag | Antiadhäsive Wirkstoffe |
JPH11501911A (ja) | 1995-03-03 | 1999-02-16 | ビー マーゴリン、ソロモン | サイトカイン成長因子の引き起こす疾病の治療 |
DE19604190A1 (de) | 1996-02-06 | 1997-08-07 | Hoechst Ag | Nagelwachstumsfördernde Zubereitungen |
EP0863981B1 (en) | 1996-08-01 | 2009-09-23 | Dale Wallis | Detection, prevention and treatment of papillomatous digital dermatitis |
JP4253047B2 (ja) | 1996-09-27 | 2009-04-08 | 杏林製薬株式会社 | 被膜形成性抗真菌剤組成物 |
JP4227677B2 (ja) | 1996-12-10 | 2009-02-18 | 杏林製薬株式会社 | 被膜形成性抗真菌剤組成物 |
FR2761886B1 (fr) | 1997-04-14 | 2000-05-05 | Virbac Sa | Compositions contenant au moins un polymere cationique et au moins une molecule active contenue dans au moins un vecteur micro ou nanoparticulaire, et leur utilisation pour le traitement de surfaces vivantes ou inertes |
US5991438A (en) | 1997-07-31 | 1999-11-23 | Hewlett-Packard Company | Color halftone error-diffusion with local brightness variation reduction |
EP0983037B1 (en) | 1998-02-09 | 2003-05-02 | MacroChem Corporation | Antifungal nail lacquer |
AU755003B2 (en) | 1998-03-17 | 2002-11-28 | Solomon B. Margolin | Topical antiseptic compositions and methods |
US6231875B1 (en) | 1998-03-31 | 2001-05-15 | Johnson & Johnson Consumer Companies, Inc. | Acidified composition for topical treatment of nail and skin conditions |
ATE269067T1 (de) | 1998-04-17 | 2004-07-15 | Bertek Pharm Inc | Topische formulierungen zur behandlung von nagel pilzerkrankungen |
US6306375B1 (en) | 1998-05-01 | 2001-10-23 | The Procter & Gamble Company | Long wear nail polish having defined surface properties |
US5965111A (en) | 1998-05-01 | 1999-10-12 | The Procter & Gamble Company | Fast drying water-borne nail polish |
US6284234B1 (en) | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
EP1143950B1 (de) | 1998-09-10 | 2005-03-09 | BioEqual AG | Topisch anwendbare mittel gegen nagelpilzerkrankungen |
DE19841796A1 (de) | 1998-09-12 | 2000-03-16 | Beiersdorf Ag | Kombinationen von Antiadhäsiva (Kohlenhydrate) und Mikrobiziden |
US6159977A (en) | 1998-11-16 | 2000-12-12 | Astan, Inc. | Therapeutic anti-fungal nail preparation |
ATE249811T1 (de) | 1999-02-09 | 2003-10-15 | Cognis Deutschland Gmbh | Verwendung von nanoskaligen chitosanen |
AU3930200A (en) | 1999-08-19 | 2001-03-19 | Lavipharm S.A. | Film forming polymers, methods of use, and devices and applications thereof |
DE19960632A1 (de) | 1999-12-16 | 2001-07-05 | Cognis Deutschland Gmbh | Kosmetische Mittel enthaltend natürliche Chitosane |
DE50012415D1 (de) | 2000-01-03 | 2006-05-11 | Karl Kraemer | Zubereitungen zur atraumatischen nagelentfernung |
KR20030016227A (ko) | 2000-02-16 | 2003-02-26 | 벤트레이 파마슈티칼스, 인코포레이티드 | 약학적 조성물 |
DE10011081A1 (de) | 2000-03-09 | 2001-09-13 | Aventis Pharma Gmbh | Antiinfektive Wirkstoffkombinationen und ihre Verwendung zur topischen Behandlung von Pilzerkrankungen der Fuß- und Fingernägel |
US7074392B1 (en) | 2000-03-27 | 2006-07-11 | Taro Pharmaceutical Industries Limited | Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections |
DE10035991A1 (de) | 2000-07-24 | 2002-02-14 | Polichem Sa | Nagellackzusammensetzung |
GB0019283D0 (en) | 2000-08-04 | 2000-09-27 | Novartis Ag | Organic compounds |
JP4899139B2 (ja) | 2000-08-10 | 2012-03-21 | 株式会社ポーラファルマ | 抗真菌医薬組成物 |
US6676953B2 (en) | 2001-01-26 | 2004-01-13 | Don L. Hexamer | Antifungal composition and method for human nails |
US20030118655A1 (en) | 2001-12-21 | 2003-06-26 | Nikhil Kundel | Film forming liquid composition |
US6921529B2 (en) | 2002-07-29 | 2005-07-26 | Joseph C. Maley | Treatment modality and method for fungal nail infection |
US8404751B2 (en) * | 2002-09-27 | 2013-03-26 | Hallux, Inc. | Subunguicide, and method for treating onychomycosis |
ATE432087T1 (de) | 2003-03-21 | 2009-06-15 | Nexmed Holdings Inc | Antimykotischer nagellack und anwendungsverfahren |
EP1491202A1 (en) | 2003-06-23 | 2004-12-29 | Polichem S.A. | Nail restructuring compositions for topical application |
US20060280703A1 (en) | 2003-07-29 | 2006-12-14 | Pascal Lefrancois | Antimycotic nail varnish |
AR045241A1 (es) | 2003-08-12 | 2005-10-19 | Novartis Consumer Health Sa | Composicion topica que comprende terbinafina e hidrocortisona |
US20050238672A1 (en) | 2004-04-27 | 2005-10-27 | Nimni Marcel E | Antifungal drug delivery |
AU2005258903A1 (en) * | 2004-07-02 | 2006-01-12 | Warner-Lambert Company Llc | Compositions and methods for treating pathological infections |
FR2892023B1 (fr) | 2005-10-14 | 2009-09-25 | Galderma Sa | Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale |
EP1958639A1 (en) | 2007-02-14 | 2008-08-20 | Polichem S.A. | Use of chitosans for the treatment of nail inflammatory diseases |
EP1958638A1 (en) | 2007-02-14 | 2008-08-20 | Polichem S.A. | Use of chitosans to increase nail growth rate |
EP1958613A1 (en) * | 2007-02-15 | 2008-08-20 | Polichem S.A. | Dermal film-forming liquid formulations for drug release to skin |
WO2008121709A1 (en) | 2007-03-30 | 2008-10-09 | Transport Pharmaceuticals, Inc. | Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug |
AU2009275230A1 (en) | 2008-07-23 | 2010-01-28 | Targeted Delivery Technologies Limited | Methods of administering topical antifungal formulations for the treatment of fungal infections |
US7903569B2 (en) | 2008-11-25 | 2011-03-08 | At&T Intellectual Property I, L.P. | Diagnosing network problems in an IPV6 dual stack network |
WO2010138674A1 (en) | 2009-05-29 | 2010-12-02 | Stiefel Laboratories, Inc. | Azole antifungal compositions |
JP5339152B2 (ja) | 2009-12-18 | 2013-11-13 | 横河電機株式会社 | 電空変換器 |
FR2954163B1 (fr) | 2009-12-18 | 2012-03-16 | Galderma Pharma Sa | Utilisation d'un tensioactif cationique, avantageu-sement amphotere, pour la preparation d'une composition antifongique applicable sur l'ongle |
EP2544659A2 (en) * | 2009-12-23 | 2013-01-16 | Nuvo Research Inc. | Highly permeating terbinafine formulation for treating onychomycosis |
EP2345643A1 (en) | 2009-12-29 | 2011-07-20 | Polichem S.A. | New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof |
RU2432158C1 (ru) | 2010-07-28 | 2011-10-27 | Закрытое акционерное общество "Институт прикладной нанотехнологии" | Профилактический бактерицидный лак для обработки ногтей |
US8697753B1 (en) * | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
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2013
- 2013-05-07 US US13/888,757 patent/US8697753B1/en active Active
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2014
- 2014-01-23 CA CA2900127A patent/CA2900127C/en active Active
- 2014-01-23 CN CN201480006685.9A patent/CN105050592B/zh active Active
- 2014-01-23 NZ NZ709668A patent/NZ709668A/en unknown
- 2014-01-23 LT LTEP14701713.1T patent/LT2953621T/lt unknown
- 2014-01-23 RS RS20190816A patent/RS58990B1/sr unknown
- 2014-01-23 SG SG11201505275YA patent/SG11201505275YA/en unknown
- 2014-01-23 MX MX2015010203A patent/MX361880B/es active IP Right Grant
- 2014-01-23 ES ES14701713T patent/ES2729373T3/es active Active
- 2014-01-23 BR BR112015018798-6A patent/BR112015018798B1/pt active IP Right Grant
- 2014-01-23 PL PL14701713T patent/PL2953621T3/pl unknown
- 2014-01-23 AU AU2014214166A patent/AU2014214166B2/en active Active
- 2014-01-23 WO PCT/EP2014/051288 patent/WO2014122024A1/en active Application Filing
- 2014-01-23 SI SI201431232T patent/SI2953621T1/sl unknown
- 2014-01-23 HU HUE14701713 patent/HUE045000T2/hu unknown
- 2014-01-23 PT PT14701713T patent/PT2953621T/pt unknown
- 2014-01-23 KR KR1020157020489A patent/KR102200788B1/ko active IP Right Grant
- 2014-01-23 US US14/765,964 patent/US10172811B2/en active Active
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