CY1123394T1 - Φαρμακευτικη συνθεση - Google Patents

Φαρμακευτικη συνθεση

Info

Publication number
CY1123394T1
CY1123394T1 CY20201100659T CY201100659T CY1123394T1 CY 1123394 T1 CY1123394 T1 CY 1123394T1 CY 20201100659 T CY20201100659 T CY 20201100659T CY 201100659 T CY201100659 T CY 201100659T CY 1123394 T1 CY1123394 T1 CY 1123394T1
Authority
CY
Cyprus
Prior art keywords
pharmaceutical composition
nitisinone
relates
tyrosinemia
compositions
Prior art date
Application number
CY20201100659T
Other languages
English (en)
Inventor
James Harrison
Stephen Fuller
Tobias Josef BROWN
Original Assignee
Cycle Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cycle Pharmaceuticals Ltd filed Critical Cycle Pharmaceuticals Ltd
Publication of CY1123394T1 publication Critical patent/CY1123394T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε στοματικές φαρμακευτικές συνθέσεις που περιλαμβάνουν νιτισινόνη ή ένα φαρμακευτικώς αποδεκτό άλας αυτής, στη χρήση τους στη θεραπεία της τυροσιναιμίας, όπως η κληρονομική τυροσιναιμία τύπου-Ι (ΗΤ-Ι) ή αλκαπτονουρία. Οι συνθέσεις έχουν βελτιωμένα χαρακτηριστικά σταθερότητας. Η εφεύρεση αναφέρεται επίσης σε μεθόδους για την παραγωγή νιτισινόνης.
CY20201100659T 2014-01-03 2020-07-20 Φαρμακευτικη συνθεση CY1123394T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1400117.6A GB201400117D0 (en) 2014-01-03 2014-01-03 Pharmaceutical composition
PCT/GB2015/050006 WO2015101794A1 (en) 2014-01-03 2015-01-05 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
CY1123394T1 true CY1123394T1 (el) 2021-12-31

Family

ID=50191740

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20201100659T CY1123394T1 (el) 2014-01-03 2020-07-20 Φαρμακευτικη συνθεση

Country Status (15)

Country Link
US (1) US10328029B2 (el)
EP (1) EP3089740B1 (el)
CA (1) CA2935013C (el)
CY (1) CY1123394T1 (el)
DK (1) DK3089740T3 (el)
ES (1) ES2806739T3 (el)
GB (1) GB201400117D0 (el)
HR (1) HRP20201135T1 (el)
HU (1) HUE050881T2 (el)
LT (1) LT3089740T (el)
PL (1) PL3089740T3 (el)
PT (1) PT3089740T (el)
RS (1) RS60551B1 (el)
SI (1) SI3089740T1 (el)
WO (1) WO2015101794A1 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITUB20160650A1 (it) * 2016-02-11 2017-08-11 Dipharma S A Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione
US9783485B1 (en) 2016-11-30 2017-10-10 Dipharma S.A. Crystalline inhibitor of 4-hydroxyphenylpyruvate dioxygenase, and a process of synthesis and crystallization thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69228813T2 (de) 1991-06-24 1999-08-05 Zeneca Ltd., London Verwendung von 2-(2-nitro-4-trifluormethylbenzoyl)-1,3-cyclohexandion zur behandlung von tyrosinämie sowie pharmazeutische zusammensetzungen
IS2385B (is) * 2006-02-10 2008-07-15 Actavis Group Hf. Klópidógrel bísúlfat lyfjasamsetningar
WO2013181292A1 (en) * 2012-05-29 2013-12-05 Biotie Therapies, Inc. Nitisinone formulations
CN102976948B (zh) 2012-11-28 2014-07-09 郑州大明药物科技有限公司 尼替西农的制备方法

Also Published As

Publication number Publication date
GB201400117D0 (en) 2014-02-19
HUE050881T2 (hu) 2021-01-28
US10328029B2 (en) 2019-06-25
DK3089740T3 (da) 2020-08-03
CA2935013A1 (en) 2015-07-09
PL3089740T3 (pl) 2020-11-02
RS60551B1 (sr) 2020-08-31
SI3089740T1 (sl) 2020-09-30
US20160324785A1 (en) 2016-11-10
WO2015101794A1 (en) 2015-07-09
ES2806739T3 (es) 2021-02-18
PT3089740T (pt) 2020-07-24
LT3089740T (lt) 2020-08-10
CA2935013C (en) 2022-08-02
EP3089740A1 (en) 2016-11-09
HRP20201135T1 (hr) 2021-01-22
EP3089740B1 (en) 2020-05-13

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