ITUB20160650A1 - Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione - Google Patents
Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandioneInfo
- Publication number
- ITUB20160650A1 ITUB20160650A1 ITUB2016A000650A ITUB20160650A ITUB20160650A1 IT UB20160650 A1 ITUB20160650 A1 IT UB20160650A1 IT UB2016A000650 A ITUB2016A000650 A IT UB2016A000650A IT UB20160650 A ITUB20160650 A IT UB20160650A IT UB20160650 A1 ITUB20160650 A1 IT UB20160650A1
- Authority
- IT
- Italy
- Prior art keywords
- trifluorometilbenzoil
- cycloesandion
- nitro
- pharmaceutical formulations
- solid stable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITUB2016A000650A ITUB20160650A1 (it) | 2016-02-11 | 2016-02-11 | Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione |
| BR112018015483-0A BR112018015483B1 (pt) | 2016-02-11 | 2017-02-09 | Formulações farmacêuticas sólidas estáveis que contêm 2-(2-nitro-4-trifluorometil- benzoil)-1,3 -ciclo-hexanodiona |
| EP17703173.9A EP3413876B1 (en) | 2016-02-11 | 2017-02-09 | Stable solid pharmaceutical formulations containing 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione |
| RU2018124482A RU2702746C1 (ru) | 2016-02-11 | 2017-02-09 | Стабильные твёрдые фармацевтические составы, содержащие 2-(2-нитро-4-трифторметилбензоил)-1,3-циклогександион |
| US15/766,665 US10888527B2 (en) | 2016-02-11 | 2017-02-09 | Stable solid pharmaceutical formulations containing 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cylcohexanedione |
| AU2017216633A AU2017216633A1 (en) | 2016-02-11 | 2017-02-09 | Stable solid pharmaceutical formulations containing 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione |
| CN201780008088.3A CN108495623B (zh) | 2016-02-11 | 2017-02-09 | 含有2-(2-硝基-4-三氟甲基-苯甲酰基)-1,3-环己二酮的稳定固体药物配制品 |
| ES17703173T ES2751746T3 (es) | 2016-02-11 | 2017-02-09 | Formulaciones farmacéuticas sólidas estables que contienen 2-(2-nitro-4-trifluorometilbenzoil)-1,3-ciclohexanodiona |
| JP2018540857A JP6827474B2 (ja) | 2016-02-11 | 2017-02-09 | ２−（２−ニトロ−４−トリフルオロメチルベンゾイル）−１，３−シクロヘキサンジオンを含有する安定な固形医薬製剤 |
| PCT/EP2017/052805 WO2017137468A1 (en) | 2016-02-11 | 2017-02-09 | Stable solid pharmaceutical formulations containing 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITUB2016A000650A ITUB20160650A1 (it) | 2016-02-11 | 2016-02-11 | Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITUB20160650A1 true ITUB20160650A1 (it) | 2017-08-11 |
Family
ID=55969291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITUB2016A000650A ITUB20160650A1 (it) | 2016-02-11 | 2016-02-11 | Formulazioni farmaceutiche solide stabili contenenti 2-(2-nitro-4-trifluorometilbenzoil)-1,3-cicloesandione |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10888527B2 (it) |
| EP (1) | EP3413876B1 (it) |
| JP (1) | JP6827474B2 (it) |
| CN (1) | CN108495623B (it) |
| AU (1) | AU2017216633A1 (it) |
| BR (1) | BR112018015483B1 (it) |
| ES (1) | ES2751746T3 (it) |
| IT (1) | ITUB20160650A1 (it) |
| RU (1) | RU2702746C1 (it) |
| WO (1) | WO2017137468A1 (it) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9783485B1 (en) | 2016-11-30 | 2017-10-10 | Dipharma S.A. | Crystalline inhibitor of 4-hydroxyphenylpyruvate dioxygenase, and a process of synthesis and crystallization thereof |
| CN112107548A (zh) * | 2020-10-30 | 2020-12-22 | 兆科药业（广州）有限公司 | 一种含有尼替西农的药物组合物及其制备方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013181292A1 (en) * | 2012-05-29 | 2013-12-05 | Biotie Therapies, Inc. | Nitisinone formulations |
| WO2015101794A1 (en) * | 2014-01-03 | 2015-07-09 | Cycle Pharmaceuticals Ltd | Pharmaceutical composition |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69228813T2 (de) | 1991-06-24 | 1999-08-05 | Zeneca Ltd., London | Verwendung von 2-(2-nitro-4-trifluormethylbenzoyl)-1,3-cyclohexandion zur behandlung von tyrosinämie sowie pharmazeutische zusammensetzungen |
| GB9501433D0 (en) | 1995-01-25 | 1995-03-15 | Zeneca Ltd | Chemical process |
| GB0504103D0 (en) | 2005-02-28 | 2005-04-06 | Syngenta Ltd | Novel method |
| RU2384330C2 (ru) * | 2007-12-18 | 2010-03-20 | Закрытое Акционерное Общество "Канонфарма Продакшн" | Композиция 3-окси-6-метил-2-этилпиридина или его фармацевтически приемлемой соли, выполненная в форме таблетки, способ ее получения и способ лечения |
| CN102395595A (zh) * | 2008-11-06 | 2012-03-28 | 生物链接治疗股份有限公司 | 不宁腿综合症和睡眠障碍的治疗 |
| US8354451B2 (en) | 2009-03-09 | 2013-01-15 | The Uwm Research Foundation, Inc. | Treatment of microbial infections with compounds that inhibit 4-hydroxyphenylpyruvate dioxygenase |
| ES2532834T3 (es) | 2010-02-26 | 2015-04-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nitisinona para el tratamiento de albinismo oculocutáneo/ocular y para aumentar la pigmentación |
| PL2723320T3 (pl) | 2011-06-23 | 2016-06-30 | Swedish Orphan Biovitrum Int Ab | Ciekła kompozycja farmaceutyczna zawierająca nityzynon |
| EP2766004A4 (en) * | 2011-10-10 | 2015-04-22 | Teva Pharma | R (+) - N-methyl-propargyl-aminoindan |
| UA117141C2 (uk) * | 2013-10-08 | 2018-06-25 | Селджин Корпорейшн | Склади (s)-3-(4-((4-(морфолінометил)бензил)оксі)-1-оксоізоіндолін-2-іл)піперидин-2,6-діону |
-
2016
- 2016-02-11 IT ITUB2016A000650A patent/ITUB20160650A1/it unknown
-
2017
- 2017-02-09 JP JP2018540857A patent/JP6827474B2/ja active Active
- 2017-02-09 WO PCT/EP2017/052805 patent/WO2017137468A1/en active Application Filing
- 2017-02-09 CN CN201780008088.3A patent/CN108495623B/zh active Active
- 2017-02-09 EP EP17703173.9A patent/EP3413876B1/en active Active
- 2017-02-09 BR BR112018015483-0A patent/BR112018015483B1/pt active IP Right Grant
- 2017-02-09 US US15/766,665 patent/US10888527B2/en active Active
- 2017-02-09 RU RU2018124482A patent/RU2702746C1/ru active
- 2017-02-09 AU AU2017216633A patent/AU2017216633A1/en not_active Abandoned
- 2017-02-09 ES ES17703173T patent/ES2751746T3/es active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013181292A1 (en) * | 2012-05-29 | 2013-12-05 | Biotie Therapies, Inc. | Nitisinone formulations |
| WO2015101794A1 (en) * | 2014-01-03 | 2015-07-09 | Cycle Pharmaceuticals Ltd | Pharmaceutical composition |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017216633A1 (en) | 2018-07-26 |
| CN108495623A (zh) | 2018-09-04 |
| US20190160014A1 (en) | 2019-05-30 |
| RU2702746C1 (ru) | 2019-10-11 |
| CN108495623B (zh) | 2021-04-20 |
| JP6827474B2 (ja) | 2021-02-10 |
| ES2751746T3 (es) | 2020-04-01 |
| BR112018015483A2 (pt) | 2018-12-18 |
| JP2019504846A (ja) | 2019-02-21 |
| EP3413876A1 (en) | 2018-12-19 |
| WO2017137468A1 (en) | 2017-08-17 |
| US10888527B2 (en) | 2021-01-12 |
| EP3413876B1 (en) | 2019-09-18 |
| BR112018015483B1 (pt) | 2021-02-02 |
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