DE19975055I1 - Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwending als Arzneimittel - Google Patents

Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwending als Arzneimittel

Info

Publication number
DE19975055I1
DE19975055I1 DE1999175055 DE19975055C DE19975055I1 DE 19975055 I1 DE19975055 I1 DE 19975055I1 DE 1999175055 DE1999175055 DE 1999175055 DE 19975055 C DE19975055 C DE 19975055C DE 19975055 I1 DE19975055 I1 DE 19975055I1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
compositions containing
propenylamines
medicines
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE1999175055
Other languages
English (en)
Inventor
Anton Dr Stutz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4328536&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE19975055(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of DE19975055I1 publication Critical patent/DE19975055I1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/04—Acyclic alcohols with carbon-to-carbon triple bonds
    • C07C33/048—Acyclic alcohols with carbon-to-carbon triple bonds with double and triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/05—Alcohols containing rings other than six-membered aromatic rings
    • C07C33/12—Alcohols containing rings other than six-membered aromatic rings containing five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Replacement Of Web Rolls (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE1999175055 1979-08-22 1980-08-06 Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwending als Arzneimittel Pending DE19975055I1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH765679 1979-08-22

Publications (1)

Publication Number Publication Date
DE19975055I1 true DE19975055I1 (de) 2000-01-27

Family

ID=4328536

Family Applications (3)

Application Number Title Priority Date Filing Date
DE1993175084 Active DE19375084I2 (de) 1979-08-22 1980-08-06 Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung als Arzneimittel
DE1999175055 Pending DE19975055I1 (de) 1979-08-22 1980-08-06 Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwending als Arzneimittel
DE8080104623T Expired DE3069633D1 (en) 1979-08-22 1980-08-06 Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE1993175084 Active DE19375084I2 (de) 1979-08-22 1980-08-06 Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung als Arzneimittel

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8080104623T Expired DE3069633D1 (en) 1979-08-22 1980-08-06 Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals

Country Status (24)

Country Link
US (1) US4755534A (de)
EP (1) EP0024587B1 (de)
JP (2) JPS5632440A (de)
AT (1) ATE10272T1 (de)
AU (1) AU538928B2 (de)
CA (1) CA1157023A (de)
CY (1) CY1410A (de)
DE (3) DE19375084I2 (de)
DK (1) DK153470C (de)
ES (1) ES8105694A1 (de)
FI (1) FI65775C (de)
HK (1) HK21588A (de)
IE (1) IE50878B1 (de)
IL (1) IL60877A (de)
KE (1) KE3775A (de)
LU (1) LU88343I2 (de)
MY (1) MY8600181A (de)
NL (1) NL930136I2 (de)
NZ (1) NZ194714A (de)
PH (1) PH22166A (de)
PT (1) PT71717B (de)
SG (1) SG89287G (de)
YU (1) YU41513B (de)
ZA (1) ZA805185B (de)

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FR2526423B1 (fr) * 1982-05-07 1987-07-10 Sandoz Sa Nouvelles amines insaturees, leur preparation et leur utilisation comme medicaments
JPS6145A (ja) * 1984-06-09 1986-01-06 Kaken Pharmaceut Co Ltd Ｎ‐（４‐ｔｅｒｔ‐ブチルベンジル）‐Ｎ‐メチル‐１‐ナフチルメチルアミンおよびそれを有効成分とする抗真菌剤
EP0191269B1 (de) * 1984-11-22 1991-03-06 Sandoz Ag Homopropargylamine
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HU211997B (en) * 1986-01-29 1996-01-29 Sandoz Ag Process to prepare n-methyl-n-(1-naphtyl-methyl)-4-(2-phenyl-propyl)-benzylamine and pharmaceutical compns. contg. it
US4751245A (en) * 1986-06-25 1988-06-14 E. R. Squibb & Sons, Inc. Antifungal derivatives of N-(6,6-dimethyl-2-hepten-4-ynyl)-1-naphthalenemethanamine and method of using same
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JPS63238060A (ja) * 1987-03-26 1988-10-04 Maruho Kk キノリン誘導体
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EP0363326A3 (de) * 1988-10-07 1991-10-09 Sandoz Ag Fungizide Amine
EP0378457B1 (de) * 1989-01-12 1994-08-03 Sumitomo Chemical Company Limited Aromatische Allylanim enthaltende warmhärtende Harzzusammensetzung
JP3116364B2 (ja) * 1989-10-02 2000-12-11 萬有製薬株式会社 エンイン誘導体の製造法
FR2673537B1 (fr) * 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
HU219480B (hu) * 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására
GB9111611D0 (en) 1991-05-30 1991-07-24 Sandoz Ltd Liposomes
JPH04138020U (ja) * 1991-06-14 1992-12-24 日立機材株式会社 バケツトエレベータ
GB9513750D0 (en) * 1995-07-06 1995-09-06 Sandoz Ltd Use of allylamines
NZ280065A (en) * 1995-09-20 1998-04-27 Apotex Inc Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives
US6075056A (en) * 1997-10-03 2000-06-13 Penederm, Inc. Antifungal/steroid topical compositions
SK5202000A3 (en) 2000-04-07 2001-12-03 Slovakofarma As Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4- inyl)-n-methyl-1-naphthalenemethylamine (terbinaphin)
DE60142962D1 (de) * 2000-06-09 2010-10-14 Merial Ltd Verfahren zur herstellung von pestiziden verbindungen
IL137364A (en) * 2000-07-18 2005-08-31 Chemagis Ltd Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol
GB0103046D0 (en) * 2001-02-07 2001-03-21 Novartis Ag Organic Compounds
US7244703B2 (en) * 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
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US20080176908A1 (en) * 2007-01-18 2008-07-24 Mcanally Weylan R Method of using squalene monooxygenase inhibitors to treat acne
US20090082469A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched terbinafine
US20100086504A1 (en) * 2008-07-23 2010-04-08 Gregor Cevc Methods of administering topical antifungal formulations for the treatment of fungal infections
EP2730271B1 (de) 2012-11-11 2018-01-24 Symrise AG Wässrige Zubereitungen
US8697753B1 (en) 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis
ES2701758T3 (es) 2013-02-27 2019-02-25 Symrise Ag Extracto de jengibre para la protección de citoblastos
CN105377355A (zh) 2013-03-14 2016-03-02 拇趾公司 治疗甲单元的感染、疾病或病症的方法
EP2862852B1 (de) 2013-10-18 2018-07-04 Symrise AG Harnstoffderivate für den Schutz von Stammzellen
ES2643590T3 (es) 2014-03-18 2017-11-23 Symrise Ag Dióxido de titanio revestido para reducir el efecto de blanqueamiento en la piel
ES2819207T3 (es) 2014-04-29 2021-04-15 Symrise Ag Mezclas activas
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DE2716943C2 (de) * 1976-04-28 1986-08-14 Sandoz-Patent-GmbH, 7850 Lörrach N-(3-Phenyl-2-propenyl)-N-(1-naphthylmethyl)-amine, ihre Verwendung und Herstellung
DE2862103D1 (en) * 1977-08-19 1982-11-18 Sandoz Ag Propenyl amines, processes for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IL60877A0 (en) 1980-10-26
DE3069633D1 (en) 1984-12-20
JPS63313753A (ja) 1988-12-21
ES494408A0 (es) 1981-06-16
YU209680A (en) 1983-10-31
PH22166A (en) 1988-06-28
MY8600181A (en) 1986-12-31
CA1157023A (en) 1983-11-15
ATE10272T1 (de) 1984-11-15
NL930136I1 (nl) 1993-11-01
ES8105694A1 (es) 1981-06-16
EP0024587A1 (de) 1981-03-11
LU88343I2 (fr) 1994-05-04
YU41513B (en) 1987-08-31
JPS5632440A (en) 1981-04-01
KE3775A (en) 1987-11-27
FI802583A (fi) 1981-02-23
CY1410A (en) 1988-04-22
IL60877A (en) 1984-08-31
FI65775B (fi) 1984-03-30
ZA805185B (en) 1982-03-31
US4755534A (en) 1988-07-05
AU538928B2 (en) 1984-09-06
EP0024587B1 (de) 1984-11-14
DK153470C (da) 1988-11-28
PT71717A (en) 1980-09-01
IE801770L (en) 1981-02-22
IE50878B1 (en) 1986-08-06
DK153470B (da) 1988-07-18
HK21588A (en) 1988-03-31
AU6159280A (en) 1981-04-16
SG89287G (en) 1988-09-30
NL930136I2 (nl) 1998-10-01
FI65775C (fi) 1984-07-10
JPH0415216B2 (de) 1992-03-17
DE19375084I2 (de) 2000-11-16
PT71717B (en) 1981-09-24
NZ194714A (en) 1984-11-09
DK357980A (da) 1981-02-23
JPS6342612B2 (de) 1988-08-24

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