CY1121291T1 - Ανοσοδοκιμασιες ενισχυσης σηματος - Google Patents
Ανοσοδοκιμασιες ενισχυσης σηματοςInfo
- Publication number
- CY1121291T1 CY1121291T1 CY20181101345T CY181101345T CY1121291T1 CY 1121291 T1 CY1121291 T1 CY 1121291T1 CY 20181101345 T CY20181101345 T CY 20181101345T CY 181101345 T CY181101345 T CY 181101345T CY 1121291 T1 CY1121291 T1 CY 1121291T1
- Authority
- CY
- Cyprus
- Prior art keywords
- immediates
- protein
- signal
- antibody
- signal strengthening
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/553—Metal or metal coated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/29—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Richettsiales (o)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Η παρούσα εφεύρεση παρέχει μεθόδους, συσκευές, συνθέσεις (π.χ., σύμπλοκα σύλληψης) και κιτ χρήσιμα για ενίσχυση της ανίχνευσης αντισωμάτων σε ένα υπό εξέταση δείγμα. Οι μέθοδοι, οι συσκευές και οι συνθέσεις χρησιμοποιούν ανιχνεύσιμα μόρια σύνδεσης Fc όπως Πρωτεΐνη Α, Πρωτεΐνη G ή/και Fc-ειδικό αντίσωμα για να ενισχύεται το σήμα ενός ανιχνευόμενου αντισώματος σε ανοσοδοκιμασίες, όπως πλευρικής ροής δοκιμασίες.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161562302P | 2011-11-21 | 2011-11-21 | |
PCT/US2012/066108 WO2013078227A1 (en) | 2011-11-21 | 2012-11-20 | Signal amplification in lateral flow and related immunoassays |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1121291T1 true CY1121291T1 (el) | 2020-05-29 |
Family
ID=48427325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20181101345T CY1121291T1 (el) | 2011-11-21 | 2018-12-14 | Ανοσοδοκιμασιες ενισχυσης σηματος |
Country Status (20)
Country | Link |
---|---|
US (4) | US9034656B2 (el) |
EP (2) | EP2783216B1 (el) |
JP (2) | JP6267650B2 (el) |
KR (2) | KR101975178B1 (el) |
CN (2) | CN104105965B (el) |
AU (2) | AU2012340722B2 (el) |
CA (1) | CA2853812C (el) |
CY (1) | CY1121291T1 (el) |
DK (2) | DK3489685T3 (el) |
ES (2) | ES2702033T3 (el) |
FI (1) | FI3489685T3 (el) |
HR (1) | HRP20182023T1 (el) |
HU (1) | HUE041414T2 (el) |
LT (1) | LT2783216T (el) |
PL (2) | PL3489685T3 (el) |
PT (2) | PT2783216T (el) |
RS (1) | RS58168B1 (el) |
SI (1) | SI2783216T1 (el) |
TR (1) | TR201818881T4 (el) |
WO (1) | WO2013078227A1 (el) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102375055A (zh) * | 2010-08-19 | 2012-03-14 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种多重检测免疫层析芯片 |
DK3489685T3 (da) | 2011-11-21 | 2023-12-04 | Zoetis Services Llc | Signalforstærkning i sidestrømning og tilsvarende immunoassays |
US10794904B2 (en) | 2013-03-15 | 2020-10-06 | Nicoya Lifesciences Inc. | Self-referencing sensor for chemical detection |
WO2015181790A1 (en) * | 2014-05-30 | 2015-12-03 | Csir | Method and device for detection of whole organism bacteria |
TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
CN104330555B (zh) * | 2014-10-22 | 2016-05-11 | 中国检验检疫科学研究院 | 检测伯氏疏螺旋体抗体的试纸、试纸制备方法及试剂盒 |
US20180003701A1 (en) * | 2015-01-21 | 2018-01-04 | Agency For Science. Techology And Research | Immunoglobulin assays using nanoparticles |
CN106290266A (zh) * | 2015-05-13 | 2017-01-04 | 上海凯创生物技术有限公司 | 一种军团菌抗体近红外荧光检测试剂盒及其用途 |
WO2017015693A1 (en) * | 2015-07-27 | 2017-02-02 | Macquarie University | Luminescent biomolecular complex and use thereof |
JP6944438B2 (ja) | 2015-08-04 | 2021-10-06 | ゾエティス サービシズ リミテッド ライアビリティ カンパニー | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
CA2996299C (en) * | 2015-08-24 | 2022-09-27 | University Of Cincinnati | Methods and compositions for the detection of fc receptor binding activity of antibodies |
CN113740533A (zh) | 2015-08-27 | 2021-12-03 | 奎多公司 | 具有两个流体流动路径用于检测和区分两个或多个分析物的免疫分析测试设备 |
CA3001918C (en) | 2015-10-15 | 2023-08-22 | Inbios International, Inc. | Multiplexed lateral flow assay systems and methods for their use |
WO2017079607A1 (en) * | 2015-11-04 | 2017-05-11 | The Trustees Of Columbia University In The City Of New York | Detection of serum anti-fada antibodies and related diagnostic methods |
USD800912S1 (en) | 2016-06-17 | 2017-10-24 | Abreos Biosciences, Inc. | Point-of-care diagnostic device |
US11680948B2 (en) | 2016-08-12 | 2023-06-20 | Abreos Biosciences, Inc. | Detection and quantification of natalizumab |
SG11201910191RA (en) | 2017-05-11 | 2019-11-28 | Univ King Abdullah Sci & Tech | A peptide capable of forming a gel for use in tissue engineering and bioprinting |
KR102418307B1 (ko) | 2017-05-11 | 2022-07-06 | 킹 압둘라 유니버시티 오브 사이언스 앤드 테크놀로지 | 미세유체공학-기반 3d 바이오프린팅용 장치 및 방법 |
CN107271676A (zh) * | 2017-07-14 | 2017-10-20 | 河南爱微迪生物技术有限公司 | 一种丙型肝炎病毒抗体唾液检测试剂盒 |
EP3665187A4 (en) * | 2017-08-08 | 2021-04-21 | OraSure Technologies, Inc. | TEST PROCEDURES FOR IMPROVED ANALYTE DETECTION |
CN107589264A (zh) * | 2017-08-31 | 2018-01-16 | 重庆康巨全弘生物科技有限公司 | 定量检测人表皮生长因受体2(her2)的双光祖荧光免疫层析试剂盒及其制备方法 |
CN107389928A (zh) * | 2017-08-31 | 2017-11-24 | 重庆康巨全弘生物科技有限公司 | 定量检测胃泌素释放肽前体(pro‑GRP)的双光子荧光免疫层析试剂盒及其制备方法 |
EP3688010A4 (en) | 2017-09-25 | 2021-08-18 | The Trustees of Columbia University in the City of New York | SEROLOGICAL TEST TO DETECT EXPOSURE TO AND INFECTION TO TICK-TRANSMITTED AGENTS |
CN108490171A (zh) * | 2018-03-02 | 2018-09-04 | 北京库尔科技有限公司 | 一种高灵敏唾液抗体检测试剂盒 |
CA3104640A1 (en) * | 2018-06-22 | 2019-12-26 | Oova, Inc. | Methods, devices, and systems for detecting analyte levels |
CN109085360A (zh) * | 2018-07-03 | 2018-12-25 | 广西医科大学 | 一套纳米生物靶向诊断反应器检测GP73、Nrp1、Frz肿瘤标志物方法及应用 |
JP7153494B2 (ja) * | 2018-07-27 | 2022-10-14 | シスメックス株式会社 | 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット |
JP2022501444A (ja) * | 2018-09-27 | 2022-01-06 | ナヴロジェン インコーポレイテッド | 抗体動態を測定するための組成物および方法 |
JP7205940B2 (ja) * | 2019-02-20 | 2023-01-17 | 株式会社パートナーファーム | 固相反応チップ及びこれを用いた測定方法 |
GB201912866D0 (en) * | 2019-09-06 | 2019-10-23 | Cambridge Molecular Diagnostics Ltd | Miltiply labelled polymetric molecule for detection assays |
WO2021216276A1 (en) * | 2020-04-24 | 2021-10-28 | Massachusetts Institute Of Technology | Rapid, point of care detection of neutralizing antibodies against a virus |
WO2021217179A1 (en) * | 2020-04-24 | 2021-10-28 | Siemens Healthcare Diagnostics Inc. | Compositions, kits, and methods for anti-microbial serology assays using anti-human immunoglobulin antibody |
US11376588B2 (en) | 2020-06-10 | 2022-07-05 | Checkable Medical Incorporated | In vitro diagnostic device |
US11673324B2 (en) | 2020-08-20 | 2023-06-13 | King Abdullah University Of Science And Technology | Nozzle for 3D bioprinting |
US20230375531A1 (en) * | 2020-09-18 | 2023-11-23 | Massachusetts Institute Of Technology | A Method Of Detecting an Analyte and Related Systems |
US20220091119A1 (en) * | 2020-09-18 | 2022-03-24 | Georgia Tech Research Corporation | Methods for the Diagnosis and Detection of Viral Analytes |
RU2748901C1 (ru) * | 2020-09-30 | 2021-06-01 | Федеральное государственное учреждение «Федеральный исследовательский центр «Фундаментальные основы биотехнологии» Российской академии наук» (ФИЦ Биотехнологии РАН) | Способ высокочувствительного иммунохроматографического анализа с двойной конкуренцией |
WO2022107089A1 (en) * | 2020-11-23 | 2022-05-27 | King Adbullah University Of Science And Technology | Developing lateral flow immunochromatography (lfia) peptide-based test strips for rapid detection of antigens and antibodies against specific antigens |
EP4295155A1 (en) * | 2021-02-17 | 2023-12-27 | Eltek S.p.A. | Kit and process for testing a state of immunization in a subject with respect to a pathogenic microorganism |
WO2023097083A1 (en) * | 2021-11-29 | 2023-06-01 | Bioventures, Llc | Lateral flow assay device and method for rapid detection of antibodies against felis catus gammaherpesvirus 1 in domestic cat blood |
CN114264820A (zh) * | 2021-12-22 | 2022-04-01 | 广东医科大学附属医院 | 一种流感病毒a型和b型量子点联检试纸条及其制备方法和应用 |
EP4220166A1 (en) * | 2022-02-01 | 2023-08-02 | Universitat Rovira I Virgili (URV) | In vitro method for detecting antibodies in a sample |
Family Cites Families (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4704366A (en) | 1984-06-22 | 1987-11-03 | Bio-Rad Laboratories, Inc. | Process for binding IgG to protein A |
US5061381A (en) | 1990-06-04 | 1991-10-29 | Abaxis, Inc. | Apparatus and method for separating cells from biological fluids |
US5186844A (en) | 1991-04-01 | 1993-02-16 | Abaxis, Inc. | Apparatus and method for continuous centrifugal blood cell separation |
US5122284A (en) | 1990-06-04 | 1992-06-16 | Abaxis, Inc. | Apparatus and method for optically analyzing biological fluids |
US5413732A (en) | 1991-08-19 | 1995-05-09 | Abaxis, Inc. | Reagent compositions for analytical testing |
US5304348A (en) | 1992-02-11 | 1994-04-19 | Abaxis, Inc. | Reagent container for analytical rotor |
WO1993019827A1 (en) | 1992-04-02 | 1993-10-14 | Abaxis, Inc. | Analytical rotor with dye mixing chamber |
JP3706214B2 (ja) * | 1996-10-28 | 2005-10-12 | 株式会社三菱化学ヤトロン | 免疫学的分析方法 |
US5939021A (en) | 1997-01-23 | 1999-08-17 | Hansen; W. Peter | Homogeneous binding assay |
JP4209471B2 (ja) | 1997-02-20 | 2009-01-14 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | プラズモン共鳴粒子、方法、および装置 |
US6344272B1 (en) | 1997-03-12 | 2002-02-05 | Wm. Marsh Rice University | Metal nanoshells |
US7144627B2 (en) | 1997-03-12 | 2006-12-05 | William Marsh Rice University | Multi-layer nanoshells comprising a metallic or conducting shell |
US6699724B1 (en) | 1998-03-11 | 2004-03-02 | Wm. Marsh Rice University | Metal nanoshells for biosensing applications |
JP2000028612A (ja) * | 1998-07-07 | 2000-01-28 | Nitto Denko Corp | 免疫学的検査方法および免疫学的検査キット |
JP3841559B2 (ja) * | 1998-07-07 | 2006-11-01 | 日東電工株式会社 | 免疫学的検査方法および免疫学的検査キット |
JP3298836B2 (ja) * | 1998-11-12 | 2002-07-08 | アークレイ株式会社 | 検体分析用具 |
CA2381568A1 (en) | 1999-07-30 | 2001-02-08 | The Penn State Research Foundation | Instruments, methods and reagents for surface plasmon resonance |
AU3081301A (en) | 1999-11-12 | 2001-06-06 | Surromed, Inc. | Biosensing using surface plasmon resonance |
WO2002059226A2 (en) | 2000-11-03 | 2002-08-01 | Wm. Marsh Rice University | Partial coverage metal nanoshells and method of making same |
US6861263B2 (en) | 2001-01-26 | 2005-03-01 | Surromed, Inc. | Surface-enhanced spectroscopy-active sandwich nanoparticles |
US7135054B2 (en) | 2001-09-26 | 2006-11-14 | Northwestern University | Nanoprisms and method of making them |
CN1417586A (zh) * | 2001-11-05 | 2003-05-14 | 福州市迈新生物技术开发公司 | 一种免疫检测信号放大系统和它的制备方法及其应用 |
US6970239B2 (en) | 2002-06-12 | 2005-11-29 | Intel Corporation | Metal coated nanocrystalline silicon as an active surface enhanced Raman spectroscopy (SERS) substrate |
US7212692B2 (en) | 2002-11-08 | 2007-05-01 | Ming Yan | Multiple array surface plasmon resonance biosensor |
JP4787938B2 (ja) | 2003-03-28 | 2011-10-05 | ザ・プロウボウスト・フェロウズ・ファウンデーション・スカラーズ・アンド・ザ・アザー・メンバーズ・オブ・ボード・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン | 銀ナノ粒子を用いた検体検出用センサ |
KR100531760B1 (ko) * | 2003-04-28 | 2005-11-29 | 대한민국(관리부서 : 농림부 국립수의과학검역원) | 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트 |
US20060240573A1 (en) | 2003-07-29 | 2006-10-26 | Lamdagen, Llc | Optical system including nanostructures for biological or chemical sensing |
GB0321937D0 (en) | 2003-09-19 | 2003-10-22 | Univ Liverpool | Nanoparticle conjugates and method of production thereof |
JP4109205B2 (ja) | 2004-01-07 | 2008-07-02 | 富士フイルム株式会社 | 被検体検出方法 |
WO2007040559A2 (en) | 2004-11-17 | 2007-04-12 | Bioveris | Electrochemiluminescent assay |
CN1296492C (zh) | 2004-11-18 | 2007-01-24 | 博奥生物有限公司 | 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法 |
US7405054B1 (en) | 2004-12-13 | 2008-07-29 | University Of Washington Uw Tech Transfer - Invention Licensing | Signal amplification method for surface plasmon resonance-based chemical detection |
US8628727B2 (en) | 2005-04-08 | 2014-01-14 | Northwestern University | Compositions, devices and methods for SERS and LSPR |
US20060246513A1 (en) | 2005-05-02 | 2006-11-02 | Bohannon Robert C | Method and device to detect the presence of analytes in a sample |
US8101424B2 (en) | 2005-06-15 | 2012-01-24 | University Of Maryland, Baltimore County | Bioassays using plasmonic scattering from noble metal nanostructures |
US20070092978A1 (en) | 2005-10-20 | 2007-04-26 | Ronald Mink | Target ligand detection |
JP5442179B2 (ja) | 2005-10-21 | 2014-03-12 | アルフレッサファーマ株式会社 | 反応性物質が結合した微小粒子の沈降抑制方法および該微小粒子含有試薬 |
CA2632703A1 (en) | 2005-10-25 | 2008-03-13 | Louisiana Tech University Research Foundation | Multilayer films, coatings and microcapsules comprising polypeptides |
CN101360997B (zh) * | 2005-11-18 | 2013-05-01 | 美国政府健康及人类服务部,疾病控制和预防中心 | 改性心磷脂及其应用 |
US7790066B2 (en) | 2006-03-03 | 2010-09-07 | William Marsh Rice University | Nanorice particles: hybrid plasmonic nanostructures |
JP4810304B2 (ja) | 2006-05-12 | 2011-11-09 | キヤノン株式会社 | 化学センサ素子及びその製造方法 |
US8426152B2 (en) | 2007-01-03 | 2013-04-23 | Lamdagen Corporation | Enzymatic assay for LSPR |
EP2755031B1 (en) | 2007-03-20 | 2017-05-03 | Becton, Dickinson and Company | Assay using surface-enhanced raman spectroscopy (sers)-active particles |
JP2009150708A (ja) | 2007-12-19 | 2009-07-09 | Canon Inc | 標的物質の検出方法及び検査キット |
WO2009081386A2 (en) | 2007-12-21 | 2009-07-02 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | A process for preparing nanoparticles |
JP5511095B2 (ja) | 2008-03-20 | 2014-06-04 | アバクシス, インコーポレイテッド | ゾル粒子特異的結合アッセイの多波長分析 |
WO2010006201A2 (en) | 2008-07-10 | 2010-01-14 | Abaxis, Inc. | Methods of reducing non-specific interaction in metal nanoparticle assays |
CA2742678C (en) | 2008-12-03 | 2020-03-31 | Abaxis, Inc. | Lateral flow strip assay with immobilized conjugate |
US8313915B2 (en) * | 2009-01-21 | 2012-11-20 | Gundersen Lutheran Medical Foundation, Inc. | Early detection of canine lyme disease by specific peptides and antibodies |
WO2010091293A1 (en) | 2009-02-06 | 2010-08-12 | The Regents Of The University Of California | Plasmonic system for detecting binding of biological molecules |
PL2401392T3 (pl) | 2009-02-27 | 2017-08-31 | Beckman Coulter, Inc. | Homogeniczne oznaczenia fazy roztworu |
WO2010116345A1 (en) | 2009-04-08 | 2010-10-14 | National University Of Ireland, Galway | Silver nanoplates |
JP5563789B2 (ja) | 2009-06-11 | 2014-07-30 | 富士フイルム株式会社 | 検出方法 |
US20110095636A1 (en) | 2009-10-27 | 2011-04-28 | Chiu-Fa Lee | Magnetic force based automatic power generation device |
CA2781110C (en) | 2009-11-17 | 2018-07-31 | Abaxis, Inc. | Peptides and methods for the detection of lyme disease antibodies |
KR101892182B1 (ko) * | 2009-11-20 | 2018-08-24 | 아박시스, 인크. | 에를리키아 항체의 검출을 위한 펩티드, 장치 및 방법 |
US8597897B2 (en) | 2009-11-24 | 2013-12-03 | Korea Research Institute Of Bioscience And Biotechnology | Method of rapidly detecting microorganisms using nanoparticles |
US9308582B2 (en) | 2009-12-24 | 2016-04-12 | Yi Sun | Solution stable and chemically reactive metallic nanoparticles |
EP2354792A1 (en) * | 2010-02-08 | 2011-08-10 | Biomonitor A/S | Method for detecting anti-drug antibodies |
EP2564203B1 (en) | 2010-04-27 | 2017-06-07 | Ventana Medical Systems, Inc. | Antibody-nanoparticle conjugates and methods for making and using such conjugates |
KR20130095175A (ko) | 2010-05-28 | 2013-08-27 | 고쿠리츠다이가쿠호진 토쿄고교 다이가꾸 | 금속 미립자 복합체 및 그 제조 방법 |
WO2012077756A1 (ja) | 2010-12-08 | 2012-06-14 | 公立大学法人大阪府立大学 | 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法 |
CN102103145B (zh) * | 2011-02-24 | 2013-01-16 | 南京基蛋生物科技有限公司 | 一种双放大系统的胶体金试纸条及其制备方法 |
US8697129B2 (en) | 2011-03-02 | 2014-04-15 | Imra America, Inc. | Stable colloidal gold nanoparticles with controllable surface modification and functionalization |
US8784895B2 (en) | 2011-03-15 | 2014-07-22 | Northwestern University | Multifunctional metal nanoparticles having a polydopamine-based surface and methods of making and using the same |
US20130230717A1 (en) | 2011-09-02 | 2013-09-05 | Washington University In St. Louis | Copper nanostructures and methods for their preparation |
US8758772B2 (en) * | 2011-11-04 | 2014-06-24 | Abaxis, Inc. | Peptides and methods for the detection of lyme disease antibodies |
DK3489685T3 (da) | 2011-11-21 | 2023-12-04 | Zoetis Services Llc | Signalforstærkning i sidestrømning og tilsvarende immunoassays |
US9823246B2 (en) | 2011-12-28 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon |
US20130189793A1 (en) | 2012-01-20 | 2013-07-25 | Wei Qian | Stable Colloidal Suspensions Of Gold Nanoconjugates And The Method For Preparing The Same |
EP2810067A4 (en) | 2012-01-31 | 2015-12-09 | American University Of Cairo Auc | DIRECT DETECTION OF BIOMARKERS FROM DISEASE IN CLINICAL SAMPLES USING CATIONIC NANOPARTICLE BASED ASSAYS AND VERSATILE AND GREEN METHODS FOR THE SYNTHESIS OF ANISOTROPIC SILVER NANOSTRUCTURES |
EP2625966A1 (en) | 2012-02-13 | 2013-08-14 | Bionanoplus, S.L. | Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof |
TWI435843B (zh) | 2012-04-27 | 2014-05-01 | Univ Nat Taiwan | 奈米顆粒的製造方法 |
TW201408690A (zh) | 2012-05-05 | 2014-03-01 | Academia Sinica | 二氨基苯甲酸或鄰苯二胺共軛的胜肽作為功能性的醣類標幟劑 |
WO2014058904A1 (en) | 2012-10-11 | 2014-04-17 | Nanocomposix, Inc. | Silver nanoplate compositions and methods |
US9651546B2 (en) * | 2012-10-11 | 2017-05-16 | Abaxis, Inc. | Peptides, devices, and methods for the detection of ehrlichia antibodies |
US9441301B2 (en) | 2012-12-06 | 2016-09-13 | Nanyang Technological University | Method for forming a bimetallic core-shell nanostructure |
EP2968526A4 (en) | 2013-03-14 | 2016-11-09 | Abbott Lab | ANTIGEN-ANTIBODY COMBINATION ASSAY OF HEPATITIS C VIRUS AND METHODS AND COMPOSITIONS FOR USE THEREWITH |
JP2016512241A (ja) | 2013-03-14 | 2016-04-25 | アボット・ラボラトリーズAbbott Laboratories | 改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体 |
WO2014197222A1 (en) | 2013-06-05 | 2014-12-11 | Purdue Research Foundation | Titanium nitride plasmonic nanoparticles for clinical therapeutic applications |
US20150038355A1 (en) | 2013-07-30 | 2015-02-05 | Bio-Rad Laboratories, Inc. | Multiplex blocker beads for immunoassays |
CN106233140A (zh) | 2014-02-26 | 2016-12-14 | 莱姆达仁公司 | 用于增强测定灵敏度的数字lspr |
US10024800B2 (en) | 2014-04-15 | 2018-07-17 | Rutgers, The State University Of New Jersey | Gold nanostar substrates for SERS sensing in the femtomolar regime |
WO2016007942A1 (en) | 2014-07-11 | 2016-01-14 | Northwestern University | Synthesis of uniform anisotropic nanoparticles |
WO2016017037A1 (ja) | 2014-08-01 | 2016-02-04 | 株式会社ビークル | 免疫学的測定法に用いられるウイルス様粒子、それに用いられるブロッキング剤、及びこれらを含むキット |
TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
EP3259286A4 (en) | 2015-02-19 | 2018-07-11 | Ionica Sciences | Reagents and methods for detecting infectious diseases |
WO2016170183A1 (en) | 2015-04-24 | 2016-10-27 | Pharmadiagnostics Nv | Improved method of measuring an interaction between molecules |
JP6944438B2 (ja) | 2015-08-04 | 2021-10-06 | ゾエティス サービシズ リミテッド ライアビリティ カンパニー | 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
AU2018212009B2 (en) | 2017-01-30 | 2022-07-14 | Zoetis Services Llc | Solution-based plasmon specific-binding partner assays and metallic nanostructures |
-
2012
- 2012-11-20 DK DK18196372.9T patent/DK3489685T3/da active
- 2012-11-20 DK DK12852350.3T patent/DK2783216T3/da active
- 2012-11-20 HU HUE12852350A patent/HUE041414T2/hu unknown
- 2012-11-20 PT PT12852350T patent/PT2783216T/pt unknown
- 2012-11-20 SI SI201231492T patent/SI2783216T1/sl unknown
- 2012-11-20 PL PL18196372.9T patent/PL3489685T3/pl unknown
- 2012-11-20 TR TR2018/18881T patent/TR201818881T4/tr unknown
- 2012-11-20 US US13/682,306 patent/US9034656B2/en active Active
- 2012-11-20 ES ES12852350T patent/ES2702033T3/es active Active
- 2012-11-20 LT LTEP12852350.3T patent/LT2783216T/lt unknown
- 2012-11-20 FI FIEP18196372.9T patent/FI3489685T3/fi active
- 2012-11-20 KR KR1020147013716A patent/KR101975178B1/ko active IP Right Grant
- 2012-11-20 JP JP2014542574A patent/JP6267650B2/ja active Active
- 2012-11-20 AU AU2012340722A patent/AU2012340722B2/en active Active
- 2012-11-20 CN CN201280057143.5A patent/CN104105965B/zh active Active
- 2012-11-20 EP EP12852350.3A patent/EP2783216B1/en active Active
- 2012-11-20 PT PT181963729T patent/PT3489685T/pt unknown
- 2012-11-20 CN CN201610403886.3A patent/CN106124757B/zh active Active
- 2012-11-20 PL PL12852350T patent/PL2783216T3/pl unknown
- 2012-11-20 RS RS20181486A patent/RS58168B1/sr unknown
- 2012-11-20 EP EP18196372.9A patent/EP3489685B1/en active Active
- 2012-11-20 CA CA2853812A patent/CA2853812C/en active Active
- 2012-11-20 KR KR1020197012067A patent/KR102065387B1/ko active IP Right Grant
- 2012-11-20 WO PCT/US2012/066108 patent/WO2013078227A1/en active Application Filing
- 2012-11-20 ES ES18196372T patent/ES2966741T3/es active Active
-
2015
- 2015-04-16 US US14/688,419 patent/US9921218B2/en active Active
-
2017
- 2017-12-22 JP JP2017245671A patent/JP6742978B2/ja active Active
-
2018
- 2018-02-01 US US15/886,290 patent/US10281465B2/en active Active
- 2018-06-29 AU AU2018204793A patent/AU2018204793B2/en active Active
- 2018-11-30 HR HRP20182023TT patent/HRP20182023T1/hr unknown
- 2018-12-14 CY CY20181101345T patent/CY1121291T1/el unknown
-
2019
- 2019-03-20 US US16/359,142 patent/US11255854B2/en active Active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1121291T1 (el) | Ανοσοδοκιμασιες ενισχυσης σηματος | |
CY1123708T1 (el) | Αντισωματα που συνδεονται προς τον ανθρωπινο προσδετη 1 (pd-l1) προγραμματισμενου θανατου | |
CY1119972T1 (el) | Προσδιορισμος για αντισωματα ιου jc | |
CY1121872T1 (el) | Αξιολογηση, δοκιμασιες και θεραπεια των pkal-μεσολαβουμενων διαταραχων | |
ATE556030T1 (de) | Ultrasensitiver nachweis von analyten | |
BRPI0607323A2 (pt) | composições e uso de polipeptìdeos e kits para a detecção de anticorpo que se liga especificamente a um polipeptìdeo | |
CY1118748T1 (el) | Πολυπλεγμενοι προσδιορισμοι βασιζομενοι σε απταμερη | |
EA201992748A1 (ru) | Диагностические анализы для обнаружения, количественного определения и/или отслеживания микроорганизмов и других аналитов | |
TR201900160T4 (tr) | Bir anti-ilaç antikoru varlığının veya miktarının saptanmasına yönelik analizler. | |
BR112013023540A2 (pt) | anticorpo, kit e método para a determinação de peptídeos amilóides | |
MX2007010349A (es) | Composiciones y metodos para clasificar muestras biologicas. | |
GB201102037D0 (en) | Microfluidics based assay device | |
MX362075B (es) | Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo. | |
CY1115624T1 (el) | Μεθοδος ανιχνευσης σε καποιο βιολογικο δειγμα των ειδικων αντισωματων για τα αβ | |
MX2013003161A (es) | Dispositivos, metodos y kits de inmunocromatografia. | |
TR201902171T4 (tr) | Bir numune içindeki bir molekülün yakalanmasına yönelik metot. | |
ATE471512T1 (de) | Verwendung des proteins s100a 12 als marker für kolorektalkarzinom | |
EA201991506A1 (ru) | Системы и способы для тестирования и скрининга с использованием связанных с соединениями субстратов | |
ZA202002415B (en) | Detection of symmetrical dimethylarginine | |
CY1123180T1 (el) | Συστημα ανιχνευσης που αξιοποιει αλυσιδωτη αντιδραση πολυμερασης | |
EA201500377A1 (ru) | Способ обнаружения анализируемого вещества и определение его концентрации с использованием намагничиваемых гранул | |
ATE468535T1 (de) | Verwendung von nnmt als marker für lungenkrebs | |
GB201119585D0 (en) | Assay | |
CY1113013T1 (el) | Βελτιωμενες μεθοδοι ανοσολογικων δοκιμασιων | |
CY1121482T1 (el) | Ευαισθητη πολυπλεκτικη ανοσοδοκιμασια για τους διαλυτους υποδοχεις των αυξητικων παραγοντων των ινοβλαστων |