PT2783216T - Imunoensaios de amplificação de sinal - Google Patents

Imunoensaios de amplificação de sinal

Info

Publication number
PT2783216T
PT2783216T PT12852350T PT12852350T PT2783216T PT 2783216 T PT2783216 T PT 2783216T PT 12852350 T PT12852350 T PT 12852350T PT 12852350 T PT12852350 T PT 12852350T PT 2783216 T PT2783216 T PT 2783216T
Authority
PT
Portugal
Prior art keywords
immunoassays
signal amplification
amplification
signal
amplification immunoassays
Prior art date
Application number
PT12852350T
Other languages
English (en)
Inventor
Cuesico Cristina
Walker Jeremy
K Mehra Rajesh
P Aron Kenneth
M Bleile Dennis
Original Assignee
Abay Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abay Sa filed Critical Abay Sa
Publication of PT2783216T publication Critical patent/PT2783216T/pt

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553Metal or metal coated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/29Assays involving biological materials from specific organisms or of a specific nature from bacteria from Richettsiales (o)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PT12852350T 2011-11-21 2012-11-20 Imunoensaios de amplificação de sinal PT2783216T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161562302P 2011-11-21 2011-11-21

Publications (1)

Publication Number Publication Date
PT2783216T true PT2783216T (pt) 2018-12-19

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ID=48427325

Family Applications (2)

Application Number Title Priority Date Filing Date
PT12852350T PT2783216T (pt) 2011-11-21 2012-11-20 Imunoensaios de amplificação de sinal
PT181963729T PT3489685T (pt) 2011-11-21 2012-11-20 Amplificação de sinais em imunoensaios de fluxo lateral e relacionados

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT181963729T PT3489685T (pt) 2011-11-21 2012-11-20 Amplificação de sinais em imunoensaios de fluxo lateral e relacionados

Country Status (20)

Country Link
US (4) US9034656B2 (pt)
EP (2) EP2783216B1 (pt)
JP (2) JP6267650B2 (pt)
KR (2) KR101975178B1 (pt)
CN (2) CN104105965B (pt)
AU (2) AU2012340722B2 (pt)
CA (1) CA2853812C (pt)
CY (1) CY1121291T1 (pt)
DK (2) DK3489685T3 (pt)
ES (2) ES2702033T3 (pt)
FI (1) FI3489685T3 (pt)
HR (1) HRP20182023T1 (pt)
HU (2) HUE064603T2 (pt)
LT (1) LT2783216T (pt)
PL (2) PL2783216T3 (pt)
PT (2) PT2783216T (pt)
RS (1) RS58168B1 (pt)
SI (1) SI2783216T1 (pt)
TR (1) TR201818881T4 (pt)
WO (1) WO2013078227A1 (pt)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102375055A (zh) * 2010-08-19 2012-03-14 中国人民解放军军事医学科学院微生物流行病研究所 一种多重检测免疫层析芯片
SI2783216T1 (sl) 2011-11-21 2019-01-31 Abaxis, Inc. Imunološki preskusi ojačanja signala
US10794904B2 (en) * 2013-03-15 2020-10-06 Nicoya Lifesciences Inc. Self-referencing sensor for chemical detection
ES2628677B2 (es) * 2014-05-30 2018-08-09 Csir Método y dispositivo para detección de bacterias enteras
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
CN104330555B (zh) * 2014-10-22 2016-05-11 中国检验检疫科学研究院 检测伯氏疏螺旋体抗体的试纸、试纸制备方法及试剂盒
US20180003701A1 (en) * 2015-01-21 2018-01-04 Agency For Science. Techology And Research Immunoglobulin assays using nanoparticles
CN106290266A (zh) * 2015-05-13 2017-01-04 上海凯创生物技术有限公司 一种军团菌抗体近红外荧光检测试剂盒及其用途
WO2017015693A1 (en) * 2015-07-27 2017-02-02 Macquarie University Luminescent biomolecular complex and use thereof
WO2017024163A1 (en) 2015-08-04 2017-02-09 Abaxis, Inc. Signal amplification in solution-based plasmonic specific-binding partner assays
WO2017035185A1 (en) * 2015-08-24 2017-03-02 University Of Cincinnati Methods and compositions for the detection of fc receptor binding activity of antibodies
EP3341730A1 (en) * 2015-08-27 2018-07-04 Quidel Corporation Immunoassay test device with two fluid flow paths for detection and differentiation of two or more analytes
WO2017066645A1 (en) 2015-10-15 2017-04-20 Inbios International, Inc. Multiplexed lateral flow assay systems and methods for their use
EP3371331A1 (en) * 2015-11-04 2018-09-12 The Trustees of Columbia University in the City of New York Detection of serum anti-fada antibodies and related diagnostic methods
USD800912S1 (en) 2016-06-17 2017-10-24 Abreos Biosciences, Inc. Point-of-care diagnostic device
US11680948B2 (en) 2016-08-12 2023-06-20 Abreos Biosciences, Inc. Detection and quantification of natalizumab
IL295118A (en) 2017-01-30 2022-09-01 Zoetis Services Llc Solution-based specific plasmon binding assays and metallic nanostructures
US11472839B2 (en) 2017-05-11 2022-10-18 King Abdullah University Of Science And Technology Peptide capable of forming a gel for use in tissue engineering and bioprinting
SG11201910173YA (en) 2017-05-11 2019-11-28 Univ King Abdullah Sci & Tech Device and method for microfluidics-based 3d bioprinting
CN107271676A (zh) * 2017-07-14 2017-10-20 河南爱微迪生物技术有限公司 一种丙型肝炎病毒抗体唾液检测试剂盒
US20200371100A1 (en) * 2017-08-08 2020-11-26 Orasure Technologies, Inc. Assay methods for improved analyte detection
CN107389928A (zh) * 2017-08-31 2017-11-24 重庆康巨全弘生物科技有限公司 定量检测胃泌素释放肽前体(pro‑GRP)的双光子荧光免疫层析试剂盒及其制备方法
CN107589264A (zh) * 2017-08-31 2018-01-16 重庆康巨全弘生物科技有限公司 定量检测人表皮生长因受体2(her2)的双光祖荧光免疫层析试剂盒及其制备方法
WO2019060885A1 (en) 2017-09-25 2019-03-28 The Trustees Of Columbia University In The City Of New York SEROLOGICAL ASSAY FOR THE DETECTION OF EXPOSURE TO PATHOGENIC AGENTS CARRIED OUT BY TICKS AND INFECTION THEREOF
CN108490171A (zh) * 2018-03-02 2018-09-04 北京库尔科技有限公司 一种高灵敏唾液抗体检测试剂盒
CA3104640A1 (en) * 2018-06-22 2019-12-26 Oova, Inc. Methods, devices, and systems for detecting analyte levels
CN109085360A (zh) * 2018-07-03 2018-12-25 广西医科大学 一套纳米生物靶向诊断反应器检测GP73、Nrp1、Frz肿瘤标志物方法及应用
JP7153494B2 (ja) * 2018-07-27 2022-10-14 シスメックス株式会社 生体粒子の測定方法、非特異シグナルの検出方法、生体粒子測定方法及び生体粒子を検出するための試薬キット
EP3857235A4 (en) * 2018-09-27 2022-09-28 Navrogen COMPOSITION AND METHODS OF MEASUREMENT OF ANTIBODY DYNAMICS
KR20210127945A (ko) * 2019-02-20 2021-10-25 가부시키가이샤 파트너 펌 고상 반응 칩 및 이것을 사용한 측정 방법
GB201912866D0 (en) * 2019-09-06 2019-10-23 Cambridge Molecular Diagnostics Ltd Miltiply labelled polymetric molecule for detection assays
CN115397464A (zh) * 2020-04-24 2022-11-25 美国西门子医学诊断股份有限公司 用于使用抗人免疫球蛋白抗体的抗微生物血清学测定的组合物、试剂盒和方法
EP4138913A1 (en) * 2020-04-24 2023-03-01 Massachusetts Institute of Technology Rapid, point of care detection of neutralizing antibodies against a virus
WO2021252810A1 (en) 2020-06-10 2021-12-16 Checkable Medical Incorporated In vitro diagnostic device
US11673324B2 (en) 2020-08-20 2023-06-13 King Abdullah University Of Science And Technology Nozzle for 3D bioprinting
WO2022061371A1 (en) * 2020-09-18 2022-03-24 Georgia Tech Research Corporation Methods for the diagnosis and detection of viral analytes
EP4214507A1 (en) * 2020-09-18 2023-07-26 Massachusetts Institute Of Technology A method of detecting an analyte and related systems
RU2748901C1 (ru) * 2020-09-30 2021-06-01 Федеральное государственное учреждение «Федеральный исследовательский центр «Фундаментальные основы биотехнологии» Российской академии наук» (ФИЦ Биотехнологии РАН) Способ высокочувствительного иммунохроматографического анализа с двойной конкуренцией
US11994520B2 (en) 2020-11-23 2024-05-28 King Abdullah University Of Science And Technology Developing lateral flow immunochromatography (LFIA) peptide-based test strips for rapid detection of antigens and antibodies against specific antigens
WO2022175842A1 (en) * 2021-02-17 2022-08-25 Eltek S.P.A. Kit and process for testing a state of immunization in a subject with respect to a pathogenic microorganism
WO2023097083A1 (en) * 2021-11-29 2023-06-01 Bioventures, Llc Lateral flow assay device and method for rapid detection of antibodies against felis catus gammaherpesvirus 1 in domestic cat blood
CN114264820A (zh) * 2021-12-22 2022-04-01 广东医科大学附属医院 一种流感病毒a型和b型量子点联检试纸条及其制备方法和应用
EP4220166A1 (en) * 2022-02-01 2023-08-02 Universitat Rovira I Virgili (URV) In vitro method for detecting antibodies in a sample

Family Cites Families (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704366A (en) 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
US5122284A (en) 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
US5061381A (en) 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US5186844A (en) 1991-04-01 1993-02-16 Abaxis, Inc. Apparatus and method for continuous centrifugal blood cell separation
US5413732A (en) 1991-08-19 1995-05-09 Abaxis, Inc. Reagent compositions for analytical testing
US5304348A (en) 1992-02-11 1994-04-19 Abaxis, Inc. Reagent container for analytical rotor
AU4047493A (en) 1992-04-02 1993-11-08 Abaxis, Inc. Analytical rotor with dye mixing chamber
JP3706214B2 (ja) * 1996-10-28 2005-10-12 株式会社三菱化学ヤトロン 免疫学的分析方法
US5939021A (en) 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
AU748939B2 (en) 1997-02-20 2002-06-13 Regents Of The University Of California, The Plasmon resonant particles, methods and apparatus
US6344272B1 (en) 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US7144627B2 (en) 1997-03-12 2006-12-05 William Marsh Rice University Multi-layer nanoshells comprising a metallic or conducting shell
US6699724B1 (en) 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
JP3841559B2 (ja) * 1998-07-07 2006-11-01 日東電工株式会社 免疫学的検査方法および免疫学的検査キット
JP2000028612A (ja) * 1998-07-07 2000-01-28 Nitto Denko Corp 免疫学的検査方法および免疫学的検査キット
JP3298836B2 (ja) * 1998-11-12 2002-07-08 アークレイ株式会社 検体分析用具
CA2381568A1 (en) 1999-07-30 2001-02-08 The Penn State Research Foundation Instruments, methods and reagents for surface plasmon resonance
EP1236034A4 (en) 1999-11-12 2006-05-03 Surromed Inc PLASMON RESONANCE SURFACE BIODETECTION
WO2002079764A1 (en) 2001-01-26 2002-10-10 Nanoplex Technologies, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
WO2002059226A2 (en) 2000-11-03 2002-08-01 Wm. Marsh Rice University Partial coverage metal nanoshells and method of making same
US7135054B2 (en) 2001-09-26 2006-11-14 Northwestern University Nanoprisms and method of making them
CN1417586A (zh) * 2001-11-05 2003-05-14 福州市迈新生物技术开发公司 一种免疫检测信号放大系统和它的制备方法及其应用
US6970239B2 (en) 2002-06-12 2005-11-29 Intel Corporation Metal coated nanocrystalline silicon as an active surface enhanced Raman spectroscopy (SERS) substrate
US7212692B2 (en) 2002-11-08 2007-05-01 Ming Yan Multiple array surface plasmon resonance biosensor
JP4787938B2 (ja) 2003-03-28 2011-10-05 ザ・プロウボウスト・フェロウズ・ファウンデーション・スカラーズ・アンド・ザ・アザー・メンバーズ・オブ・ボード・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン 銀ナノ粒子を用いた検体検出用センサ
KR100531760B1 (ko) * 2003-04-28 2005-11-29 대한민국(관리부서 : 농림부 국립수의과학검역원) 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
US20060240573A1 (en) 2003-07-29 2006-10-26 Lamdagen, Llc Optical system including nanostructures for biological or chemical sensing
GB0321937D0 (en) 2003-09-19 2003-10-22 Univ Liverpool Nanoparticle conjugates and method of production thereof
JP4109205B2 (ja) 2004-01-07 2008-07-02 富士フイルム株式会社 被検体検出方法
JP2008521007A (ja) 2004-11-17 2008-06-19 バイオヴェリス コーポレイション 電気化学発光測定法
CN1296492C (zh) 2004-11-18 2007-01-24 博奥生物有限公司 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
US7405054B1 (en) 2004-12-13 2008-07-29 University Of Washington Uw Tech Transfer - Invention Licensing Signal amplification method for surface plasmon resonance-based chemical detection
US8628727B2 (en) 2005-04-08 2014-01-14 Northwestern University Compositions, devices and methods for SERS and LSPR
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
EP1915610A4 (en) 2005-06-15 2010-05-19 Univ Maryland Biotech Inst BIOASSAYS WITH PLASMONIC SPREADING OF PRECIOUS METAL NANOSTRUCTURES
US20070092978A1 (en) * 2005-10-20 2007-04-26 Ronald Mink Target ligand detection
JP5442179B2 (ja) 2005-10-21 2014-03-12 アルフレッサファーマ株式会社 反応性物質が結合した微小粒子の沈降抑制方法および該微小粒子含有試薬
WO2007050569A2 (en) 2005-10-25 2007-05-03 Donald Templeton Haynie Polypeptide multilayer films and methods
WO2007061793A2 (en) * 2005-11-18 2007-05-31 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SCIENCES, CENTERS FOR DISEASE CONTROL AND PREVENTION Modified cardiolipin and uses therefor
US7790066B2 (en) 2006-03-03 2010-09-07 William Marsh Rice University Nanorice particles: hybrid plasmonic nanostructures
JP4810304B2 (ja) 2006-05-12 2011-11-09 キヤノン株式会社 化学センサ素子及びその製造方法
US8426152B2 (en) 2007-01-03 2013-04-23 Lamdagen Corporation Enzymatic assay for LSPR
MX2009009994A (es) 2007-03-20 2009-10-19 Becton Dickinson Co Ensayos que usan particulas activas para espectroscopia raman mejorada por superficie (sers).
JP2009150708A (ja) 2007-12-19 2009-07-09 Canon Inc 標的物質の検出方法及び検査キット
WO2009081386A2 (en) 2007-12-21 2009-07-02 The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin A process for preparing nanoparticles
JP5511095B2 (ja) 2008-03-20 2014-06-04 アバクシス, インコーポレイテッド ゾル粒子特異的結合アッセイの多波長分析
WO2010006201A2 (en) 2008-07-10 2010-01-14 Abaxis, Inc. Methods of reducing non-specific interaction in metal nanoparticle assays
CA2742678C (en) 2008-12-03 2020-03-31 Abaxis, Inc. Lateral flow strip assay with immobilized conjugate
US8313915B2 (en) * 2009-01-21 2012-11-20 Gundersen Lutheran Medical Foundation, Inc. Early detection of canine lyme disease by specific peptides and antibodies
WO2010091293A1 (en) 2009-02-06 2010-08-12 The Regents Of The University Of California Plasmonic system for detecting binding of biological molecules
HUE031737T2 (en) 2009-02-27 2017-07-28 Beckman Coulter Inc Solution phase homogeneous tests
WO2010116345A1 (en) 2009-04-08 2010-10-14 National University Of Ireland, Galway Silver nanoplates
JP5563789B2 (ja) 2009-06-11 2014-07-30 富士フイルム株式会社 検出方法
US20110095636A1 (en) 2009-10-27 2011-04-28 Chiu-Fa Lee Magnetic force based automatic power generation device
EP2501719B1 (en) * 2009-11-17 2015-11-04 Abaxis, Inc. Peptides and methods for the detection of lyme disease antibodies
WO2011063235A2 (en) * 2009-11-20 2011-05-26 Abaxis, Inc. Peptides, devices, and methods for the detection of ehrlichia antibodies
KR101256628B1 (ko) 2009-11-24 2013-04-19 한국생명공학연구원 나노입자를 이용한 미생물의 고속 검출방법
US9308582B2 (en) 2009-12-24 2016-04-12 Yi Sun Solution stable and chemically reactive metallic nanoparticles
EP2354792A1 (en) * 2010-02-08 2011-08-10 Biomonitor A/S Method for detecting anti-drug antibodies
ES2636908T3 (es) 2010-04-27 2017-10-10 Ventana Medical Systems, Inc. Conjugados de nanopartícula-anticuerpo y procedimientos para producir y usar dichos conjugados
EP2579022A4 (en) 2010-05-28 2014-01-08 Tokyo Inst Tech METAL MICROPARTICLE COMPOSITE AND METHOD OF MANUFACTURING THEREOF
JP5822239B2 (ja) 2010-12-08 2015-11-24 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法
CN102103145B (zh) * 2011-02-24 2013-01-16 南京基蛋生物科技有限公司 一种双放大系统的胶体金试纸条及其制备方法
US8697129B2 (en) 2011-03-02 2014-04-15 Imra America, Inc. Stable colloidal gold nanoparticles with controllable surface modification and functionalization
WO2012125693A2 (en) 2011-03-15 2012-09-20 Northwestern University Multifunctional metal nanoparticles having a polydopamine-based surface and methods of making and using the same
US20130230717A1 (en) 2011-09-02 2013-09-05 Washington University In St. Louis Copper nanostructures and methods for their preparation
US8758772B2 (en) * 2011-11-04 2014-06-24 Abaxis, Inc. Peptides and methods for the detection of lyme disease antibodies
SI2783216T1 (sl) 2011-11-21 2019-01-31 Abaxis, Inc. Imunološki preskusi ojačanja signala
US9823246B2 (en) 2011-12-28 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon
DE112013000636T5 (de) 2012-01-20 2014-10-09 Imra America, Inc. Stabile Kolloidale Suspensionen aus Goldnanokonjugaten und das Verfahren zur Zubereitung derselben
WO2013116513A2 (en) 2012-01-31 2013-08-08 American University Of Cairo (Auc) Direct detection of disease biomarkers in clinical specimens using cationic nanoparticle-based assays & versatile and green methods forsynthesis of anisotropic silver nanostructures
EP2625966A1 (en) 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof
TWI435843B (zh) 2012-04-27 2014-05-01 Univ Nat Taiwan 奈米顆粒的製造方法
TW201408690A (zh) 2012-05-05 2014-03-01 Academia Sinica 二氨基苯甲酸或鄰苯二胺共軛的胜肽作為功能性的醣類標幟劑
IL305614B1 (en) 2012-10-11 2024-05-01 Nanocomposix Inc Compositions of silver nanoparticle coating and methods
JP6325553B2 (ja) 2012-10-11 2018-05-16 アバクシス, インコーポレイテッド エールリヒア抗体の検出のためのペプチド、デバイス、および方法
US9441301B2 (en) 2012-12-06 2016-09-13 Nanyang Technological University Method for forming a bimetallic core-shell nanostructure
CN105209616A (zh) 2013-03-14 2015-12-30 雅培制药有限公司 用于改进的抗体检测的hcv ns3重组抗原及其突变体
CA2906421C (en) 2013-03-14 2022-08-16 George J. Dawson Hcv antigen-antibody combination assay and methods and compositions for use therein
EP3003190A4 (en) 2013-06-05 2016-04-13 Purdue Research Foundation PLASMONIC NANOPARTICLES BASED ON TITANIUM NITRIDE FOR CLINICAL THERAPEUTIC APPLICATIONS
EP3028043A4 (en) 2013-07-30 2017-04-19 Bio-rad Laboratories, Inc. Multiplex blocker beads for immunoassays
TW201538959A (zh) 2014-02-26 2015-10-16 Lamdagen Corp 用於增強分析靈敏度之數位局域表面電漿子共振(lspr)
WO2015160923A1 (en) 2014-04-15 2015-10-22 Rutgers, The State University Of New Jersey Gold nanostar substrates for sers sensing in the femtomolar regime
US10518331B2 (en) 2014-07-11 2019-12-31 Northwestern University Synthesis of uniform anisotropic nanoparticles
WO2016017037A1 (ja) 2014-08-01 2016-02-04 株式会社ビークル 免疫学的測定法に用いられるウイルス様粒子、それに用いられるブロッキング剤、及びこれらを含むキット
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
CA2976963A1 (en) 2015-02-19 2016-08-25 Ionica Sciences Reagents and methods for detecting infectious diseases
WO2016170183A1 (en) 2015-04-24 2016-10-27 Pharmadiagnostics Nv Improved method of measuring an interaction between molecules
WO2017024163A1 (en) 2015-08-04 2017-02-09 Abaxis, Inc. Signal amplification in solution-based plasmonic specific-binding partner assays
IL295118A (en) 2017-01-30 2022-09-01 Zoetis Services Llc Solution-based specific plasmon binding assays and metallic nanostructures

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