CY1121872T1 - Αξιολογηση, δοκιμασιες και θεραπεια των pkal-μεσολαβουμενων διαταραχων - Google Patents

Αξιολογηση, δοκιμασιες και θεραπεια των pkal-μεσολαβουμενων διαταραχων

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Publication number
CY1121872T1
CY1121872T1 CY20191100391T CY191100391T CY1121872T1 CY 1121872 T1 CY1121872 T1 CY 1121872T1 CY 20191100391 T CY20191100391 T CY 20191100391T CY 191100391 T CY191100391 T CY 191100391T CY 1121872 T1 CY1121872 T1 CY 1121872T1
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CY
Cyprus
Prior art keywords
pkal
mediated
evaluation
treatment
testing
Prior art date
Application number
CY20191100391T
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English (en)
Inventor
Kusumam Joseph
Allen P. Kaplan
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Dyax Corp.
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Publication date
Application filed by Dyax Corp. filed Critical Dyax Corp.
Publication of CY1121872T1 publication Critical patent/CY1121872T1/el

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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
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Abstract

Η εφεύρεση παρέχει μεθόδους δοκιμασιών για την ανίχνευση του αναστολέα πρωτεάσης C1 πλάσματος (C1-INH) που προσδένεται στην καλλικρεΐνη πλάσματος, στον Παράγοντα XII ή και στα δύο και χρήσεις αυτών για την ταυτοποίηση υποκειμένων που βρίσκονται σε κίνδυνο ή πάσχουν από μια μεσολαβούμενη από pKal ή μεσολαβούμενη από βραδυκινίνη διαταραχή. Οι παρεχόμενες μέθοδοι επιτρέπουν την ανάλυση ασθενών με μεσολαβούμενο από καλλικρεΐνη πλάσματος αγγειοοίδημα (ΚΜΑ) ή άλλες νόσους που μεσολαβούνται από την pKal, χρήσιμες στην αξιολόγηση και τη θεραπεία.
CY20191100391T 2013-01-20 2019-04-09 Αξιολογηση, δοκιμασιες και θεραπεια των pkal-μεσολαβουμενων διαταραχων CY1121872T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361754600P 2013-01-20 2013-01-20
PCT/US2014/012090 WO2014113701A1 (en) 2013-01-20 2014-01-17 Evaluation, assays and treatment of pkal-mediated disorders

Publications (1)

Publication Number Publication Date
CY1121872T1 true CY1121872T1 (el) 2020-10-14

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Country Status (21)

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US (2) US10690670B2 (el)
EP (2) EP3470837A1 (el)
JP (3) JP6656926B2 (el)
KR (3) KR102658793B1 (el)
CN (2) CN110208533B (el)
AU (3) AU2014207409B2 (el)
CA (1) CA2898446A1 (el)
CY (1) CY1121872T1 (el)
DK (1) DK2946206T3 (el)
ES (1) ES2718347T3 (el)
HK (1) HK1214361A1 (el)
HR (1) HRP20190528T1 (el)
HU (1) HUE044285T2 (el)
IL (1) IL239957B (el)
LT (1) LT2946206T (el)
PL (1) PL2946206T3 (el)
PT (1) PT2946206T (el)
RS (1) RS58635B1 (el)
SI (1) SI2946206T1 (el)
TR (1) TR201904638T4 (el)
WO (1) WO2014113701A1 (el)

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CN117192130A (zh) 2016-09-16 2023-12-08 武田药品工业株式会社 用于接触活化系统相关的疾病的蛋白生物标记
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