CY1120132T1 - Χρηση ρ3 πρωτεϊνων συντηξης βακτηριοφαγου ως παραγοντων δεσμευσης αμυλοειδους - Google Patents

Χρηση ρ3 πρωτεϊνων συντηξης βακτηριοφαγου ως παραγοντων δεσμευσης αμυλοειδους

Info

Publication number
CY1120132T1
CY1120132T1 CY20171100988T CY171100988T CY1120132T1 CY 1120132 T1 CY1120132 T1 CY 1120132T1 CY 20171100988 T CY20171100988 T CY 20171100988T CY 171100988 T CY171100988 T CY 171100988T CY 1120132 T1 CY1120132 T1 CY 1120132T1
Authority
CY
Cyprus
Prior art keywords
amyloid
bacteriopheus
concentrates
fusion protein
protein factors
Prior art date
Application number
CY20171100988T
Other languages
English (en)
Inventor
Rajaraman Krishnan
Richard Fisher
Original Assignee
Proclara Biosciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proclara Biosciences, Inc. filed Critical Proclara Biosciences, Inc.
Publication of CY1120132T1 publication Critical patent/CY1120132T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/00033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14111—Inoviridae
    • C12N2795/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14111—Inoviridae
    • C12N2795/14133—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η εφεύρεση αναφέρεται σε παράγοντες και φαρμακευτικές συνθέσεις για τη μείωση σχηματισμού αμυλοειδούς και/ή την προαγωγή αποσυσσωμάτωσης πρωτεϊνών αμυλοειδούς. Οι συνθέσεις μπορούν επίσης να χρησιμοποιηθούν για την ανίχνευση αμυλοειδούς.
CY20171100988T 2012-10-02 2017-09-20 Χρηση ρ3 πρωτεϊνων συντηξης βακτηριοφαγου ως παραγοντων δεσμευσης αμυλοειδους CY1120132T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261708709P 2012-10-02 2012-10-02
US201261730316P 2012-11-27 2012-11-27
US201361801349P 2013-03-15 2013-03-15
US201361828105P 2013-05-28 2013-05-28
PCT/US2013/062862 WO2014055515A1 (en) 2012-10-02 2013-10-01 Use of p3 of bacteriophage fusion proteins as amyloid binding agents

Publications (1)

Publication Number Publication Date
CY1120132T1 true CY1120132T1 (el) 2018-12-12

Family

ID=49354958

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20171100988T CY1120132T1 (el) 2012-10-02 2017-09-20 Χρηση ρ3 πρωτεϊνων συντηξης βακτηριοφαγου ως παραγοντων δεσμευσης αμυλοειδους

Country Status (25)

Country Link
US (3) US9688728B2 (el)
EP (1) EP2906235B1 (el)
JP (1) JP6283366B2 (el)
KR (1) KR102101258B1 (el)
CN (1) CN104870008B (el)
AR (1) AR092879A1 (el)
AU (1) AU2013327472B2 (el)
BR (1) BR112015007424A2 (el)
CY (1) CY1120132T1 (el)
DK (1) DK2906235T3 (el)
EA (1) EA033666B1 (el)
ES (1) ES2641373T3 (el)
HK (1) HK1213775A1 (el)
HR (1) HRP20171413T1 (el)
HU (1) HUE036893T2 (el)
IL (1) IL238021B (el)
LT (1) LT2906235T (el)
MX (1) MX358755B (el)
NZ (1) NZ706838A (el)
PL (1) PL2906235T3 (el)
PT (1) PT2906235T (el)
SI (1) SI2906235T1 (el)
TW (1) TWI613212B (el)
WO (1) WO2014055515A1 (el)
ZA (1) ZA201502940B (el)

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JP2016526044A (ja) 2013-05-28 2016-09-01 ニューロファージ ファーマシューティカルズ， インコーポレイテッド 低減された免疫原性を有する修飾されたバクテリオファージｇ３ｐアミノ酸配列を含むポリペプチド
TW201632542A (zh) * 2014-12-03 2016-09-16 神經噬菌體製藥股份有限公司 包含缺乏醣基化信號之修飾噬菌體ｇ３ｐ胺基酸序列的多肽
TW202336236A (zh) * 2015-03-27 2023-09-16 美商再生元醫藥公司 偵測生物污染物之組成物及方法
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Also Published As

Publication number Publication date
EA033666B1 (ru) 2019-11-14
DK2906235T3 (en) 2017-09-25
JP6283366B2 (ja) 2018-02-21
AU2013327472A1 (en) 2015-05-21
US10208090B2 (en) 2019-02-19
BR112015007424A2 (pt) 2021-04-20
CN104870008B (zh) 2019-10-01
IL238021A0 (en) 2015-05-31
MX2015004119A (es) 2015-10-26
HK1213775A1 (zh) 2016-07-15
LT2906235T (lt) 2017-10-25
ES2641373T3 (es) 2017-11-08
TW201418279A (zh) 2014-05-16
KR102101258B1 (ko) 2020-04-16
US20180354994A1 (en) 2018-12-13
US20150376239A1 (en) 2015-12-31
US10526377B2 (en) 2020-01-07
US9688728B2 (en) 2017-06-27
AU2013327472A2 (en) 2015-06-04
JP2015532290A (ja) 2015-11-09
AU2013327472B2 (en) 2017-10-26
HRP20171413T1 (hr) 2017-12-15
US20170305975A1 (en) 2017-10-26
KR20150063544A (ko) 2015-06-09
TWI613212B (zh) 2018-02-01
HUE036893T2 (hu) 2018-08-28
EP2906235A1 (en) 2015-08-19
PL2906235T3 (pl) 2017-12-29
PT2906235T (pt) 2017-09-28
EA201590690A1 (ru) 2016-04-29
EP2906235B1 (en) 2017-07-19
WO2014055515A1 (en) 2014-04-10
NZ706838A (en) 2017-06-30
ZA201502940B (en) 2017-11-29
CN104870008A (zh) 2015-08-26
SI2906235T1 (sl) 2017-12-29
MX358755B (es) 2018-09-03
AR092879A1 (es) 2015-05-06
IL238021B (en) 2019-06-30

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