CY1121341T1 - Δοκιμες για την ανιχνευση της παρουσιας ή της ποσοτητας αντισωματος κατα αντισωματος φαρμακου - Google Patents

Δοκιμες για την ανιχνευση της παρουσιας ή της ποσοτητας αντισωματος κατα αντισωματος φαρμακου

Info

Publication number
CY1121341T1
CY1121341T1 CY20191100037T CY191100037T CY1121341T1 CY 1121341 T1 CY1121341 T1 CY 1121341T1 CY 20191100037 T CY20191100037 T CY 20191100037T CY 191100037 T CY191100037 T CY 191100037T CY 1121341 T1 CY1121341 T1 CY 1121341T1
Authority
CY
Cyprus
Prior art keywords
antibodies
detection
tests
antibodies against
against drug
Prior art date
Application number
CY20191100037T
Other languages
English (en)
Inventor
Ryan GRABERT
Susan Richards
Valerie THEOBALD
Yuanxin Xu
Jad ZOGHBI
Original Assignee
Genzyme Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corporation filed Critical Genzyme Corporation
Publication of CY1121341T1 publication Critical patent/CY1121341T1/el

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2430/00—Assays, e.g. immunoassays or enzyme assays, involving synthetic organic compounds as analytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Μέθοδοι και εξοπλισμός για την ανίχνευση αντισωμάτων (π.χ. αντισώματα κατά αντισώματος φαρμάκου). Τέτοιες μέθοδοι και εξοπλισμός επιτρέπουν την ανίχνευση, για παράδειγμα, αντισωμάτων κατά αντισώματος φαρμάκου σε υγρά του ανθρώπινου σώματος, όπως το αίμα, το πλάσμα και ο ορός αίματος.
CY20191100037T 2014-02-11 2019-01-14 Δοκιμες για την ανιχνευση της παρουσιας ή της ποσοτητας αντισωματος κατα αντισωματος φαρμακου CY1121341T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461938556P 2014-02-11 2014-02-11
PCT/US2015/015442 WO2015123315A1 (en) 2014-02-11 2015-02-11 Assays for detecting the presence or amount of an anti-drug antibody

Publications (1)

Publication Number Publication Date
CY1121341T1 true CY1121341T1 (el) 2020-05-29

Family

ID=52684652

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100037T CY1121341T1 (el) 2014-02-11 2019-01-14 Δοκιμες για την ανιχνευση της παρουσιας ή της ποσοτητας αντισωματος κατα αντισωματος φαρμακου

Country Status (19)

Country Link
US (3) US9759732B2 (el)
EP (4) EP3667321B1 (el)
CN (1) CN106164670B (el)
AU (2) AU2015217261B2 (el)
CA (1) CA2939080A1 (el)
CY (1) CY1121341T1 (el)
DK (1) DK3105592T3 (el)
ES (1) ES2705403T3 (el)
HR (1) HRP20190026T1 (el)
HU (1) HUE041669T2 (el)
LT (1) LT3105592T (el)
MX (2) MX2016010413A (el)
PL (1) PL3105592T3 (el)
PT (1) PT3105592T (el)
RS (1) RS58212B1 (el)
SG (2) SG11201606291VA (el)
SI (1) SI3105592T1 (el)
TR (1) TR201900160T4 (el)
WO (1) WO2015123315A1 (el)

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CN112285351A (zh) * 2019-07-22 2021-01-29 上海益诺思生物技术股份有限公司 一种抗IgE单抗的ELISA检测方法
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CN111024958B (zh) * 2020-03-11 2020-06-23 同昕生物技术（北京）有限公司 用于检测单抗药物和抗单抗药物抗体的试剂及其应用
JP2023524062A (ja) * 2020-05-01 2023-06-08 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 治療用タンパク質に対する中和抗体アッセイ
JP7478040B2 (ja) * 2020-06-25 2024-05-02 シスメックス株式会社 Ａβペプチドの測定方法及びその方法に用いられる試薬組成物
CN116261662B (zh) * 2020-10-14 2024-05-31 天境生物科技(上海)有限公司 用于减轻输血前测定中治疗性抗cd47抗体的干扰的方法
JP7062803B1 (ja) 2021-03-31 2022-05-06 積水メディカル株式会社 抗薬物抗体測定方法
CA3240046A1 (en) 2021-12-14 2023-06-22 Cdr-Life Ag Dual mhc-targeting t cell engager
CN114047343B (zh) * 2022-01-13 2022-05-31 美迪西普亚医药科技(上海)有限公司 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用
WO2024052517A2 (en) 2022-09-09 2024-03-14 Bayer Aktiengesellschaft Medical use of ccr8 antibodies and dosing schedule
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Also Published As

Publication number Publication date
SI3105592T1 (sl) 2019-02-28
MX2020009021A (es) 2020-10-12
MX2016010413A (es) 2016-11-30
US11215623B2 (en) 2022-01-04
CN106164670B (zh) 2019-06-14
RS58212B1 (sr) 2019-03-29
PL3105592T3 (pl) 2019-04-30
HUE041669T2 (hu) 2019-05-28
US20220187327A1 (en) 2022-06-16
AU2015217261B2 (en) 2020-08-27
US9759732B2 (en) 2017-09-12
PT3105592T (pt) 2019-01-23
EP3422001B1 (en) 2020-03-25
TR201900160T4 (tr) 2019-02-21
EP3667321A1 (en) 2020-06-17
CN106164670A (zh) 2016-11-23
SG11201606291VA (en) 2016-08-30
ES2705403T3 (es) 2019-03-25
AU2020264316A1 (en) 2020-11-26
AU2015217261A1 (en) 2016-09-08
US20180088140A1 (en) 2018-03-29
US11927596B2 (en) 2024-03-12
DK3105592T3 (en) 2019-02-04
HRP20190026T1 (hr) 2019-02-22
SG10201906750XA (en) 2019-09-27
LT3105592T (lt) 2019-01-25
EP3105592A1 (en) 2016-12-21
EP3105592B1 (en) 2018-10-17
EP3667321B1 (en) 2022-07-27
US20150226758A1 (en) 2015-08-13
EP4137816A1 (en) 2023-02-22
EP3422001A1 (en) 2019-01-02
CA2939080A1 (en) 2015-08-20
WO2015123315A1 (en) 2015-08-20

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