CY1118694T1 - Μεθοδοι διαχωρισμου σωματιδιων χρησιμοποιωντας μια συσκευη με ενα στοιχειο διαχωρισμου με διακριση μεγεθους που εχει μια επιμηκη αιχμη - Google Patents

Μεθοδοι διαχωρισμου σωματιδιων χρησιμοποιωντας μια συσκευη με ενα στοιχειο διαχωρισμου με διακριση μεγεθους που εχει μια επιμηκη αιχμη

Info

Publication number
CY1118694T1
CY1118694T1 CY20171100298T CY171100298T CY1118694T1 CY 1118694 T1 CY1118694 T1 CY 1118694T1 CY 20171100298 T CY20171100298 T CY 20171100298T CY 171100298 T CY171100298 T CY 171100298T CY 1118694 T1 CY1118694 T1 CY 1118694T1
Authority
CY
Cyprus
Prior art keywords
size
distribution
cells
methods
subject
Prior art date
Application number
CY20171100298T
Other languages
English (en)
Inventor
Georgi Hvichia
Original Assignee
Angle North America, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angle North America, Inc. filed Critical Angle North America, Inc.
Publication of CY1118694T1 publication Critical patent/CY1118694T1/el

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0272—Investigating particle size or size distribution with screening; with classification by filtering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N2015/0288—Sorting the particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Food Science & Technology (AREA)
  • Ecology (AREA)
  • Hospice & Palliative Care (AREA)
  • Fluid Mechanics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Combined Means For Separation Of Solids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Η εφεύρεση αναφέρεται στον διαχωρισμό των μεγαλύτερων σωματιδίων των κυττάρων που επιλέγονται από τα κύτταρα όγκου κυκλοφορίας και τα ενδοθηλιακά κύτταρα κυκλοφορίας από τα κύτταρα αίματος σε ένα δείγμα υγρού π.χ. δείγμα ανθρώπινου αίματος, με βάση την αδυναμία μεγαλύτερων σωματιδίων των κυττάρων να διασχίσουν αυτό το βήμα διαχωρισμού μιας συσκευής που προορίζεται για τον συγκεκριμένο σκοπό.
CY20171100298T 2013-03-15 2017-03-07 Μεθοδοι διαχωρισμου σωματιδιων χρησιμοποιωντας μια συσκευη με ενα στοιχειο διαχωρισμου με διακριση μεγεθους που εχει μια επιμηκη αιχμη CY1118694T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361794468P 2013-03-15 2013-03-15
US14/077,811 US9631179B2 (en) 2013-03-15 2013-11-12 Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge
EP14159725.2A EP2790020B9 (en) 2013-03-15 2014-03-14 Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge

Publications (1)

Publication Number Publication Date
CY1118694T1 true CY1118694T1 (el) 2017-07-12

Family

ID=50287917

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20161100434T CY1117533T1 (el) 2013-03-15 2016-05-20 Μεθοδοι διαχωρισμου σωματιδιων χρησιμοποιωντας μια συσκευη με ενα στοιχειο διαχωρισμου με διακριση μεγεθους που εχει μια επιμηκη αιχμη
CY20171100298T CY1118694T1 (el) 2013-03-15 2017-03-07 Μεθοδοι διαχωρισμου σωματιδιων χρησιμοποιωντας μια συσκευη με ενα στοιχειο διαχωρισμου με διακριση μεγεθους που εχει μια επιμηκη αιχμη

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20161100434T CY1117533T1 (el) 2013-03-15 2016-05-20 Μεθοδοι διαχωρισμου σωματιδιων χρησιμοποιωντας μια συσκευη με ενα στοιχειο διαχωρισμου με διακριση μεγεθους που εχει μια επιμηκη αιχμη

Country Status (20)

Country Link
US (6) US9631179B2 (el)
EP (2) EP3029465B1 (el)
JP (2) JP6066950B2 (el)
CN (3) CN106834423A (el)
AU (2) AU2014201576B2 (el)
BR (1) BR102014006329A2 (el)
CA (1) CA2845390C (el)
CY (2) CY1117533T1 (el)
DK (2) DK3029465T3 (el)
ES (2) ES2573120T3 (el)
HK (1) HK1247667A1 (el)
HR (2) HRP20160395T1 (el)
HU (2) HUE028597T2 (el)
LT (1) LT3029465T (el)
MX (2) MX356042B (el)
PL (2) PL2790020T3 (el)
PT (1) PT3029465T (el)
RS (2) RS55796B1 (el)
SI (2) SI3029465T1 (el)
SM (1) SMT201600152B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2492711B (en) 2010-04-27 2016-03-23 Halliburton Energy Services Inc Fracture characterization by interferometric drillbit imaging, time reversal imaging of fractures using drill bit seismics, and monitoring of fracture
US9631179B2 (en) * 2013-03-15 2017-04-25 Angle North America, Inc. Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge
CN107427788B (zh) * 2015-03-16 2021-03-19 卢米耐克斯公司 用于多阶梯通道乳化的仪器和方法
GB201617722D0 (en) 2016-10-19 2016-11-30 Univ London Queen Mary Method for determining prognosis of cancer
GB201617723D0 (en) 2016-10-19 2016-11-30 Univ London Queen Mary Method for predicting prostate cancer metastasis
CN107854936B (zh) * 2017-12-02 2023-06-20 西部新锆核材料科技有限公司 一种生物雾霾防治工作站
WO2019131173A1 (ja) * 2017-12-28 2019-07-04 株式会社村田製作所 分離回収システム及び分離回収方法
FR3087792B1 (fr) * 2018-10-29 2023-09-29 Inovotion Modele animal pour amplifier des cellules tumorales circulantes humaines ou animales
CN117258862A (zh) * 2018-12-13 2023-12-22 迪亚莱博（张家港）生物科技有限公司 一种微流控芯片的制备方法
EP3897657A2 (en) 2018-12-20 2021-10-27 Universität Basel <sup2/>? <sub2/>?+? ?na/k <ns1:sup>+</ns1:sup>?atpase inhibitors for use in the prevention or treatment of metastasis
CN109557304B (zh) * 2019-01-11 2024-10-18 广州万孚生物技术股份有限公司 免疫层析检测装置
WO2020178951A1 (en) * 2019-03-04 2020-09-10 Enplas Corporation Fluid handling device
KR102569747B1 (ko) * 2020-04-27 2023-08-25 고려대학교 산학협력단 유동채널 및 체액 내 입자 분리 장치
CN114397141B (zh) * 2021-12-10 2022-11-29 连云港市东方医院 一种神经内科临床用取液装置

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486335A (en) 1992-05-01 1996-01-23 Trustees Of The University Of Pennsylvania Analysis based on flow restriction
US5296375A (en) 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5744366A (en) 1992-05-01 1998-04-28 Trustees Of The University Of Pennsylvania Mesoscale devices and methods for analysis of motile cells
US5726026A (en) 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5637469A (en) 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
FR2824144B1 (fr) * 2001-04-30 2004-09-17 Metagenex S A R L Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel
WO2003008931A2 (en) 2001-07-17 2003-01-30 Georgi Hvichia Microstructure for particle and cell separation, identification, sorting, and manipulation
EP1671101A1 (en) 2003-10-03 2006-06-21 Vrije Universiteit Brussel Method and device for size-separating particles present in a fluid
US7846743B2 (en) * 2005-04-21 2010-12-07 California Institute Of Technology Uses of parylene membrane filters
GB0508983D0 (en) * 2005-05-03 2005-06-08 Oxford Gene Tech Ip Ltd Cell analyser
EP1795894A1 (en) * 2005-12-06 2007-06-13 Roche Diagnostics GmbH Plasma separation on a disk like device
US8036773B2 (en) * 2006-05-10 2011-10-11 Mckesson Automation Inc. System, method and corresponding apparatus for storing, retrieving and delivering unit dose blisters
WO2008130032A1 (ja) * 2007-04-19 2008-10-30 The Ritsumeikan Trust 液中粒子分級装置及び液中粒子分級方法、粒径測定装置及び粒径測定方法
WO2011028483A2 (en) 2009-08-24 2011-03-10 Parsortix, Inc. Methods and apparatus for segregation of particles, including additional sources of sample collection for separation of nucleated fetal cells
JP2011519553A (ja) * 2008-04-23 2011-07-14 パーソーティックス、インク． 粒子を分離する方法及び装置
AU2010246381B2 (en) * 2008-04-23 2013-08-15 Angle North America, Inc. Methods and apparatus for segregation of particles
US8579117B2 (en) 2008-07-24 2013-11-12 The Trustees Of Princeton University Bump array device having asymmetric gaps for segregation of particles
WO2010129441A2 (en) 2009-05-04 2010-11-11 Gpb Scientific, Llc Method for separating stem cells from their more differentiated progeny using microfluidic devices
NL1038359C2 (en) * 2010-03-31 2012-06-27 Aquamarijn Res B V Device and method for separation of circulating tumor cells.
US9880084B2 (en) * 2011-04-15 2018-01-30 The University Of British Columbia Apparatus for separation of particles
US9631179B2 (en) * 2013-03-15 2017-04-25 Angle North America, Inc. Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge

Also Published As

Publication number Publication date
ES2618511T3 (es) 2017-06-21
LT3029465T (lt) 2017-03-27
HRP20170360T1 (hr) 2017-04-21
MX2014003296A (es) 2015-02-10
US9631179B2 (en) 2017-04-25
CN107991476B (zh) 2020-03-03
HRP20160395T1 (hr) 2016-07-01
PL3029465T3 (pl) 2017-06-30
RS54749B1 (sr) 2016-10-31
JP2014224800A (ja) 2014-12-04
EP2790020B9 (en) 2016-05-18
US9939425B2 (en) 2018-04-10
HK1247667A1 (zh) 2018-09-28
CY1117533T1 (el) 2017-04-26
JP6067917B1 (ja) 2017-01-25
AU2016238956A1 (en) 2016-11-03
US20190217294A1 (en) 2019-07-18
MX362661B (es) 2019-01-28
CN107991476A (zh) 2018-05-04
CA2845390A1 (en) 2014-09-15
EP2790020A3 (en) 2014-12-24
SMT201600152B (it) 2016-07-01
SI2790020T1 (sl) 2016-08-31
CN104147853A (zh) 2014-11-19
AU2014201576B2 (en) 2016-10-13
DK3029465T3 (en) 2017-03-06
US10279349B2 (en) 2019-05-07
US9851344B2 (en) 2017-12-26
AU2014201576A1 (en) 2014-10-02
EP3029465B1 (en) 2017-01-11
PT3029465T (pt) 2017-03-10
US10583437B2 (en) 2020-03-10
RS55796B1 (sr) 2017-08-31
HUE033689T2 (en) 2017-12-28
MX356042B (es) 2018-05-09
US9861983B2 (en) 2018-01-09
CN104147853B (zh) 2018-01-12
EP2790020A2 (en) 2014-10-15
JP2017046696A (ja) 2017-03-09
US20170157609A1 (en) 2017-06-08
US20140271909A1 (en) 2014-09-18
DK2790020T3 (en) 2016-04-25
US20170160263A1 (en) 2017-06-08
CA2845390C (en) 2019-02-12
ES2573120T3 (es) 2016-06-06
SI3029465T1 (sl) 2017-04-26
HUE028597T2 (hu) 2016-12-28
EP3029465A1 (en) 2016-06-08
BR102014006329A2 (pt) 2015-01-13
EP2790020B1 (en) 2016-03-09
JP6066950B2 (ja) 2017-01-25
US20180126378A1 (en) 2018-05-10
US20180045708A1 (en) 2018-02-15
CN106834423A (zh) 2017-06-13
AU2016238956B2 (en) 2016-11-17
PL2790020T3 (pl) 2016-08-31

Similar Documents

Publication Publication Date Title
CY1118694T1 (el) Μεθοδοι διαχωρισμου σωματιδιων χρησιμοποιωντας μια συσκευη με ενα στοιχειο διαχωρισμου με διακριση μεγεθους που εχει μια επιμηκη αιχμη
CY1121341T1 (el) Δοκιμες για την ανιχνευση της παρουσιας ή της ποσοτητας αντισωματος κατα αντισωματος φαρμακου
CY1122510T1 (el) Μορια αντισωματος σε lag-3 και χρησεις αυτων
CY1121723T1 (el) Συνδυασμος anti-lag-3 αντισωματων και anti-pd-1 αντισωματων για θεραπεια ογκων
CY1121542T1 (el) Μορια αντισωματων σε pd-1 και χρηση αυτων
HK1257999A1 (zh) 用於臨床應用的分析物收集、提取、濃縮和檢測的方法和裝置
CY1124299T1 (el) Συνδυαστικες θεραπειες που περιλαμβανουν μορια αντισωματων κατα toy lag-3
HK1243207A1 (zh) 用於分類生物樣本﹑包括分析的優化和相關性的使用的方法和系統
IL251261A0 (en) Reagents and methods for the identification, enrichment and/or expansion of antigen-specific T-cells
DK3178571T3 (da) Inspektions- og sorteringssystem
EP2975631A4 (en) CHARGED PARTICLE BEAM DEVICE, SAMPLE OBSERVATION METHOD, SAMPLE PLATFORM, OBSERVATION SYSTEM, AND LIGHT EMITTING ELEMENT
EP2971141A4 (en) SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS
GB2528531B (en) Attachment and alignment device for optical sources, detectors and analysers, and modular analysis system
EP3106859A4 (en) Carbon isotope analysis device and carbon isotope analysis method
SG11201506481QA (en) Optical systems and methods for biological analysis
CY1123698T1 (el) Εμπλουτισμος κυκλοφορουντων κυτταρων ογκου μεσω εξαντλησης λευκων αιμοσφαιριων
DE102013203803B8 (de) Ionenquelle, schwerpartikelstrahl-bestrahlungsvorrichtung, ionenstrahl-antriebsverfahren und schwerpartikelstrahlen-bestrahlungsverfahren
MX2017005888A (es) Dispositivos, sistemas y metodos para la deteccion de analitos.
ZA201704163B (en) System and methods for identifying fields and tasks
BR112017008654A2 (pt) detector de malária
FR3025043B3 (fr) Système permettant de faciliter les transactions aux points de vente.
EP3054001A4 (en) Device for concentration and separation of circulating tumor cells, and method for concentration and separation of circulating tumor cells
MX2015015059A (es) Anticuerpos anti-receptor del factor de crecimiento de tipo insulinico humano 1 (anti-igf-1r) con abolicion de la union al fcrn y su uso en el tratamiento de enfermedades oculares vasculares.
PL3150988T3 (pl) System oraz sposób optycznego pomiaru stabilności i agregacji cząstek
EP2961852A4 (en) METHOD, COMPOSITIONS AND SYSTEMS FOR ANALYZING NUCLEIC ACID MOLECULES