MX362661B - Métodos para segregar partículas usando un aparato con un elemento de separación por discriminación de tamaño que tiene un borde delantero alargado. - Google Patents

Métodos para segregar partículas usando un aparato con un elemento de separación por discriminación de tamaño que tiene un borde delantero alargado.

Info

Publication number
MX362661B
MX362661B MX2017008116A MX2017008116A MX362661B MX 362661 B MX362661 B MX 362661B MX 2017008116 A MX2017008116 A MX 2017008116A MX 2017008116 A MX2017008116 A MX 2017008116A MX 362661 B MX362661 B MX 362661B
Authority
MX
Mexico
Prior art keywords
particles
leading edge
segregating
methods
size
Prior art date
Application number
MX2017008116A
Other languages
English (en)
Inventor
George Hvichia
Original Assignee
Angle North America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angle North America Inc filed Critical Angle North America Inc
Publication of MX362661B publication Critical patent/MX362661B/es

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • C12N5/0694Cells of blood, e.g. leukemia cells, myeloma cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0272Investigating particle size or size distribution with screening; with classification by filtering
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652Sorting or classification of particles or molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12Specific details about manufacturing devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N2015/0288Sorting the particles

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ecology (AREA)
  • Hospice & Palliative Care (AREA)
  • Fluid Mechanics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Combined Means For Separation Of Solids (AREA)
  • Sorting Of Articles (AREA)

Abstract

La descripción se relaciona a un aparato para segregar partículas con base en su capacidad de fluir por un pasaje escalonado; por lo menos algunas de las partículas pueden no pasar por un pasaje más estrecho unido por una etapa de segregación, teniendo como resultado la segregación de las partículas; el ancho del borde delantero de por lo menos una etapa del aparato es apreciablemente mayor que la anchura total del pasaje en el que el ocurre la etapa, permitiendo un rendimiento alto y rápido de la muestra; el aparato y los métodos descritos en la presente pueden ser utilizados para segregar partículas de una gran variedad de tipos; a manera de ejemplo, ellos pueden ser utilizados para segregar células de tumor circulantes de una muestra de sangre humana.
MX2017008116A 2013-03-15 2014-03-18 Métodos para segregar partículas usando un aparato con un elemento de separación por discriminación de tamaño que tiene un borde delantero alargado. MX362661B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361794468P 2013-03-15 2013-03-15
US14/077,811 US9631179B2 (en) 2013-03-15 2013-11-12 Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge

Publications (1)

Publication Number Publication Date
MX362661B true MX362661B (es) 2019-01-28

Family

ID=50287917

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017008116A MX362661B (es) 2013-03-15 2014-03-18 Métodos para segregar partículas usando un aparato con un elemento de separación por discriminación de tamaño que tiene un borde delantero alargado.
MX2014003296A MX356042B (es) 2013-03-15 2014-03-18 Métodos para segregar partículas usando un aparato con un elemento de separación por discriminación de tamaño que tiene un borde delantero alargado.

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MX2014003296A MX356042B (es) 2013-03-15 2014-03-18 Métodos para segregar partículas usando un aparato con un elemento de separación por discriminación de tamaño que tiene un borde delantero alargado.

Country Status (20)

Country Link
US (6) US9631179B2 (es)
EP (2) EP2790020B9 (es)
JP (2) JP6066950B2 (es)
CN (3) CN107991476B (es)
AU (2) AU2014201576B2 (es)
BR (1) BR102014006329A2 (es)
CA (1) CA2845390C (es)
CY (2) CY1117533T1 (es)
DK (2) DK3029465T3 (es)
ES (2) ES2618511T3 (es)
HK (1) HK1247667A1 (es)
HR (2) HRP20160395T1 (es)
HU (2) HUE028597T2 (es)
LT (1) LT3029465T (es)
MX (2) MX362661B (es)
PL (2) PL3029465T3 (es)
PT (1) PT3029465T (es)
RS (2) RS54749B1 (es)
SI (2) SI2790020T1 (es)
SM (1) SMT201600152B (es)

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US9631179B2 (en) * 2013-03-15 2017-04-25 Angle North America, Inc. Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge
KR102528348B1 (ko) * 2015-03-16 2023-05-03 루미넥스 코포레이션 다중-단차부 채널 에멀젼화를 위한 디바이스 및 방법
GB201617722D0 (en) 2016-10-19 2016-11-30 Univ London Queen Mary Method for determining prognosis of cancer
GB201617723D0 (en) 2016-10-19 2016-11-30 Univ London Queen Mary Method for predicting prostate cancer metastasis
CN107854936B (zh) * 2017-12-02 2023-06-20 西部新锆核材料科技有限公司 一种生物雾霾防治工作站
CN111526932B (zh) * 2017-12-28 2022-02-11 株式会社村田制作所 分离回收系统以及分离回收方法
FR3087792B1 (fr) * 2018-10-29 2023-09-29 Inovotion Modele animal pour amplifier des cellules tumorales circulantes humaines ou animales
US20220062317A1 (en) 2018-12-20 2022-03-03 Universität Basel Na+/k+ atpase inhibitors for use in the prevention or treatment of metastasis
CN109557304A (zh) * 2019-01-11 2019-04-02 广州万孚生物技术股份有限公司 免疫层析检测装置
WO2020178951A1 (en) * 2019-03-04 2020-09-10 Enplas Corporation Fluid handling device
KR102569747B1 (ko) * 2020-04-27 2023-08-25 고려대학교 산학협력단 유동채널 및 체액 내 입자 분리 장치
CN114397141B (zh) * 2021-12-10 2022-11-29 连云港市东方医院 一种神经内科临床用取液装置

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US9631179B2 (en) 2013-03-15 2017-04-25 Angle North America, Inc. Methods for segregating particles using an apparatus with a size-discriminating separation element having an elongate leading edge

Also Published As

Publication number Publication date
RS54749B1 (sr) 2016-10-31
US10279349B2 (en) 2019-05-07
HUE033689T2 (en) 2017-12-28
CY1118694T1 (el) 2017-07-12
CN107991476A (zh) 2018-05-04
SI2790020T1 (sl) 2016-08-31
AU2016238956B2 (en) 2016-11-17
CN107991476B (zh) 2020-03-03
AU2014201576A1 (en) 2014-10-02
HRP20170360T1 (hr) 2017-04-21
ES2573120T3 (es) 2016-06-06
CN104147853A (zh) 2014-11-19
US9861983B2 (en) 2018-01-09
LT3029465T (lt) 2017-03-27
SI3029465T1 (sl) 2017-04-26
EP2790020A3 (en) 2014-12-24
US20140271909A1 (en) 2014-09-18
EP3029465B1 (en) 2017-01-11
CY1117533T1 (el) 2017-04-26
JP6066950B2 (ja) 2017-01-25
EP2790020B9 (en) 2016-05-18
CN106834423A (zh) 2017-06-13
DK2790020T3 (en) 2016-04-25
AU2016238956A1 (en) 2016-11-03
RS55796B1 (sr) 2017-08-31
HRP20160395T1 (hr) 2016-07-01
JP2014224800A (ja) 2014-12-04
MX2014003296A (es) 2015-02-10
US10583437B2 (en) 2020-03-10
HUE028597T2 (hu) 2016-12-28
US9939425B2 (en) 2018-04-10
JP2017046696A (ja) 2017-03-09
CN104147853B (zh) 2018-01-12
SMT201600152B (it) 2016-07-01
US20170157609A1 (en) 2017-06-08
EP2790020A2 (en) 2014-10-15
EP2790020B1 (en) 2016-03-09
BR102014006329A2 (pt) 2015-01-13
EP3029465A1 (en) 2016-06-08
HK1247667A1 (zh) 2018-09-28
PT3029465T (pt) 2017-03-10
US20190217294A1 (en) 2019-07-18
PL3029465T3 (pl) 2017-06-30
PL2790020T3 (pl) 2016-08-31
US20170160263A1 (en) 2017-06-08
CA2845390A1 (en) 2014-09-15
ES2618511T3 (es) 2017-06-21
MX356042B (es) 2018-05-09
CA2845390C (en) 2019-02-12
US20180045708A1 (en) 2018-02-15
AU2014201576B2 (en) 2016-10-13
US9631179B2 (en) 2017-04-25
DK3029465T3 (en) 2017-03-06
US20180126378A1 (en) 2018-05-10
JP6067917B1 (ja) 2017-01-25
US9851344B2 (en) 2017-12-26

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