CY1114020T1 - 3-αμινοκυκλοπεντανοκαρβοξαμιδια ως διαμορφωτες υποδοχεα χημοκινης - Google Patents

3-αμινοκυκλοπεντανοκαρβοξαμιδια ως διαμορφωτες υποδοχεα χημοκινης

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Publication number
CY1114020T1
CY1114020T1 CY20131100427T CY131100427T CY1114020T1 CY 1114020 T1 CY1114020 T1 CY 1114020T1 CY 20131100427 T CY20131100427 T CY 20131100427T CY 131100427 T CY131100427 T CY 131100427T CY 1114020 T1 CY1114020 T1 CY 1114020T1
Authority
CY
Cyprus
Prior art keywords
cyclended
carbonsamides
aminocyl
chemokin
concentrators
Prior art date
Application number
CY20131100427T
Other languages
Greek (el)
English (en)
Inventor
Rajesh Venkateswaran Devraj
Wei Huang
Robert Owen Hughes
Jr Donald Joseph Rogier
John Isidro Trujillo
Steve Ronald Turner
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of CY1114020T1 publication Critical patent/CY1114020T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Organic Chemistry (AREA)
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  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
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  • Diabetes (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
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CY20131100427T 2008-11-26 2013-05-29 3-αμινοκυκλοπεντανοκαρβοξαμιδια ως διαμορφωτες υποδοχεα χημοκινης CY1114020T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11805308P 2008-11-26 2008-11-26
EP09774939.4A EP2370442B9 (en) 2008-11-26 2009-11-20 3-Aminocyclopentanecarboxamides as chemokine receptor modulators

Publications (1)

Publication Number Publication Date
CY1114020T1 true CY1114020T1 (el) 2016-07-27

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Country Status (38)

Country Link
US (2) US8293903B2 (cg-RX-API-DMAC7.html)
EP (1) EP2370442B9 (cg-RX-API-DMAC7.html)
JP (1) JP5108153B2 (cg-RX-API-DMAC7.html)
KR (1) KR101374412B1 (cg-RX-API-DMAC7.html)
CN (1) CN102227429B (cg-RX-API-DMAC7.html)
AP (1) AP3113A (cg-RX-API-DMAC7.html)
AU (1) AU2009321221B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0920936A2 (cg-RX-API-DMAC7.html)
CA (1) CA2743030C (cg-RX-API-DMAC7.html)
CL (1) CL2011001223A1 (cg-RX-API-DMAC7.html)
CO (1) CO6361921A2 (cg-RX-API-DMAC7.html)
CR (1) CR20110275A (cg-RX-API-DMAC7.html)
CU (1) CU24022B1 (cg-RX-API-DMAC7.html)
CY (1) CY1114020T1 (cg-RX-API-DMAC7.html)
DK (1) DK2370442T5 (cg-RX-API-DMAC7.html)
DO (1) DOP2011000154A (cg-RX-API-DMAC7.html)
EA (1) EA020470B1 (cg-RX-API-DMAC7.html)
EC (1) ECSP11011081A (cg-RX-API-DMAC7.html)
ES (1) ES2415430T3 (cg-RX-API-DMAC7.html)
GE (1) GEP20146064B (cg-RX-API-DMAC7.html)
HR (1) HRP20130409T2 (cg-RX-API-DMAC7.html)
IL (1) IL212732A (cg-RX-API-DMAC7.html)
MA (1) MA32834B1 (cg-RX-API-DMAC7.html)
ME (1) ME01144B (cg-RX-API-DMAC7.html)
MX (1) MX2011005526A (cg-RX-API-DMAC7.html)
MY (1) MY152557A (cg-RX-API-DMAC7.html)
NI (1) NI201100102A (cg-RX-API-DMAC7.html)
NZ (1) NZ592919A (cg-RX-API-DMAC7.html)
PE (1) PE20110831A1 (cg-RX-API-DMAC7.html)
PL (1) PL2370442T3 (cg-RX-API-DMAC7.html)
PT (1) PT2370442E (cg-RX-API-DMAC7.html)
RS (2) RS52810B9 (cg-RX-API-DMAC7.html)
SI (1) SI2370442T1 (cg-RX-API-DMAC7.html)
SV (1) SV2011003923A (cg-RX-API-DMAC7.html)
TN (1) TN2011000254A1 (cg-RX-API-DMAC7.html)
UA (1) UA99978C2 (cg-RX-API-DMAC7.html)
WO (1) WO2010061329A1 (cg-RX-API-DMAC7.html)
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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20130409T2 (hr) * 2008-11-26 2013-11-22 Pfizer Inc. 3-aminociklopentankarboksamidi kao modulatori kemokinskih receptora
KR101303963B1 (ko) * 2011-04-08 2013-09-05 재단법인 경기과학기술진흥원 (1ｒ,2ｒ,3ｒ)-3-아미노사이클로펜탄-1,2-디올을 포함하는 항알러지용 조성물
SG11201608303QA (en) 2014-04-04 2016-11-29 Del Mar Pharmaceuticals Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
JP2016029038A (ja) * 2014-07-17 2016-03-03 参天製薬株式会社 加齢黄斑変性の予防または治療剤
JOP20190040A1 (ar) * 2016-09-14 2019-03-10 Novartis Ag توليفة من ناهضات fxr
TWI830733B (zh) * 2018-05-11 2024-02-01 中國大陸商迪哲（江蘇）醫藥有限公司 環戊烷化合物

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015973A1 (en) 1993-12-06 1995-06-15 Cytel Corporation Cs-1 peptidomimetics, compositions and methods of using the same
US5510332A (en) 1994-07-07 1996-04-23 Texas Biotechnology Corporation Process to inhibit binding of the integrin α4 62 1 to VCAM-1 or fibronectin and linear peptides therefor
AU2964295A (en) 1994-07-11 1996-02-09 Athena Neurosciences, Inc. Inhibitors of leukocyte adhesion
US5462208A (en) 1994-08-01 1995-10-31 The Procter & Gamble Company Two-phase dispensing systems utilizing bellows pumps
US5811391A (en) 1994-08-25 1998-09-22 Cytel Corporation Cyclic CS-1 peptidomimetics, compositions and methods of using same
GB9524630D0 (en) 1994-12-24 1996-01-31 Zeneca Ltd Chemical compounds
US6306840B1 (en) 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
WO1996031206A2 (en) 1995-04-07 1996-10-10 Warner-Lambert Company Flavones and coumarins as agents for the treatment of atherosclerosis
US5704960A (en) 1995-12-20 1998-01-06 Corning, Inc. Method of forming an optical fiber for reduced polarization effects in amplifiers
GB9603741D0 (en) 1996-02-22 1996-04-24 Lin Mei Treatment of water by electrolysis
JP2000516210A (ja) 1996-07-12 2000-12-05 ロイコサイト，インコーポレーテッド ケモカインレセプターアンタゴニストとその使用方法
WO1998042656A1 (en) 1997-03-21 1998-10-01 Cytel Corporation Novel compounds
JP2002501537A (ja) 1997-05-29 2002-01-15 メルク エンド カンパニー インコーポレーテッド 細胞接着阻害薬としてのスルホンアミド類
CA2291778A1 (en) 1997-05-29 1998-12-03 Merck & Co., Inc. Heterocyclic amide compounds as cell adhesion inhibitors
ES2257808T3 (es) 1997-05-29 2006-08-01 MERCK & CO., INC. (A NEW JERSEY CORP.) Acidos biarilalcanoicos como inhibidores de adhesion celular.
ATE256699T1 (de) 1997-05-30 2004-01-15 Celltech Therapeutics Ltd Entzündungshemmende tyrosin-derivate
WO1998058902A1 (en) 1997-06-23 1998-12-30 Tanabe Seiyaku Co., Ltd. INHIBITORS OF α4β1MEDIATED CELL ADHESION
US6312689B1 (en) 1998-07-23 2001-11-06 Millennium Pharmaceuticals, Inc. Anti-CCR2 antibodies and methods of use therefor
CA2483752C (en) * 2002-04-29 2011-03-29 Merck & Co., Inc. Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
TWI262077B (en) * 2002-04-29 2006-09-21 Merck & Co Inc Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
DK1696919T3 (da) * 2003-12-18 2013-12-09 Incyte Corp 3-cycloalkylaminopyrrolidin-derivater som modulatorer af chemokinreceptorer
JP4845873B2 (ja) * 2004-03-03 2011-12-28 ケモセントリックス インコーポレーティッド 二環式および架橋した窒素複素環
AU2005237500A1 (en) 2004-04-28 2005-11-10 Merck Sharp & Dohme Corp. 3,3-disubstituted tetrahydropyranyl cyclopentyl amide modulators of chemokine receptor activity
JP4116671B2 (ja) * 2004-06-28 2008-07-09 インサイト コーポレイション ケモカイン受容体の調節剤としての３−アミノシクロペンタンカルボキサミド
MXPA06014672A (es) * 2004-06-28 2007-03-26 Incyte Corp 3-aminociclopentanocarboxamidas como moduladores de receptores de quimioquinas.
CN1976702A (zh) * 2004-06-28 2007-06-06 因赛特公司 作为趋化因子受体调节剂的3－氨基环戊烷甲酰胺类
MEP1008A (xx) * 2005-12-21 2010-02-10 Incyte Corp 3-aminociklopentankarboksamidi kao modulatori receptora hemokina
HRP20130409T2 (hr) * 2008-11-26 2013-11-22 Pfizer Inc. 3-aminociklopentankarboksamidi kao modulatori kemokinskih receptora

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