CY1109118T1 - Αντι-αγγειογονα φαρμακα πεπτιδιων - Google Patents

Αντι-αγγειογονα φαρμακα πεπτιδιων

Info

Publication number
CY1109118T1
CY1109118T1 CY20081100792T CY081100792T CY1109118T1 CY 1109118 T1 CY1109118 T1 CY 1109118T1 CY 20081100792 T CY20081100792 T CY 20081100792T CY 081100792 T CY081100792 T CY 081100792T CY 1109118 T1 CY1109118 T1 CY 1109118T1
Authority
CY
Cyprus
Prior art keywords
angiogenic peptide
peptide medicines
medicines
angiogenic
peptides
Prior art date
Application number
CY20081100792T
Other languages
English (en)
Inventor
Jack Henkin
Fortuna Haviv
Michael F Bradley
Douglas M Kalvin
Andrew J Schneider
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of CY1109118T1 publication Critical patent/CY1109118T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Πεπτίδια που έχουν τον χημικό τύπο: Α0-Α1-Α2-Α3-Α4-Α5-Α6-Α7-Α8-Α9-Α10 στον οποίον το Α0 επιλέγεται από υδρογόνο ή μια ομάδα ακυλίου· το Αιο είναι μια υδροξυομάδα ή ένα αμίδιο αμινοξέως· και τα: Α1, Α2, Α3, Α4, Α5, Α6, Α7, Α8 και Α9 είναι κατάλοιπα αμινοακυλίου ως ορίζεται σύμφωνα με το παρόν.
CY20081100792T 1998-05-22 2008-07-29 Αντι-αγγειογονα φαρμακα πεπτιδιων CY1109118T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8374598A 1998-05-22 1998-05-22
US25057499A 1999-02-16 1999-02-16
US27746699A 1999-03-26 1999-03-26
EP99927091A EP1078002B1 (en) 1998-05-22 1999-05-21 Peptide antiangiogenic drugs

Publications (1)

Publication Number Publication Date
CY1109118T1 true CY1109118T1 (el) 2014-07-02

Family

ID=27374598

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100792T CY1109118T1 (el) 1998-05-22 2008-07-29 Αντι-αγγειογονα φαρμακα πεπτιδιων

Country Status (26)

Country Link
EP (1) EP1078002B1 (el)
JP (3) JP3753612B2 (el)
KR (1) KR100447696B1 (el)
CN (1) CN1311796A (el)
AR (1) AR018371A1 (el)
AT (1) ATE396204T1 (el)
AU (1) AU764277B2 (el)
BG (1) BG65065B1 (el)
BR (1) BR9910639A (el)
CA (1) CA2329250C (el)
CO (1) CO5080726A1 (el)
CY (1) CY1109118T1 (el)
CZ (1) CZ299639B6 (el)
DE (1) DE69938782D1 (el)
ES (1) ES2307337T3 (el)
HK (1) HK1037376A1 (el)
HU (1) HUP0102579A3 (el)
NO (1) NO326871B1 (el)
NZ (1) NZ507912A (el)
PL (1) PL200471B1 (el)
PT (1) PT1078002E (el)
SI (1) SI1078002T1 (el)
SK (1) SK286554B6 (el)
TR (1) TR200003442T2 (el)
TW (1) TWI247748B (el)
WO (1) WO1999061476A1 (el)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774211B1 (en) 1998-05-22 2004-08-10 Abbott Laboratories Peptide antiangiogenic drugs
CA2622786A1 (en) * 1998-10-16 2000-04-27 Naoto Oku Neovascular-specific peptides
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
SI2319928T1 (sl) 1998-10-23 2013-08-30 Kirin-Amgen, Inc. Dimerni trombopoietinski peptidni mimetiki, ki se veĺ˝ejo na receptor mp1 in imajo trombopoietinsko aktivnost
US20020183242A1 (en) * 2001-04-11 2002-12-05 Jack Henkin Peptide antiangiogenic drugs
US20030050246A1 (en) * 2001-07-26 2003-03-13 Fortuna Haviv Peptides having antiangiogenic activity
US7169888B2 (en) 2001-10-31 2007-01-30 Abbott Laboratories Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity
CN1639188A (zh) * 2001-10-31 2005-07-13 艾博特公司 具有抗血管形成活性的七－、八－和九－肽
US7001984B2 (en) 2001-10-31 2006-02-21 Abbott Laboratories Di-, tri-, and tetra-peptides having antiangiogenic activity
US20030125260A1 (en) * 2001-10-31 2003-07-03 Fortuna Haviv Tetra-and pentapeptides having antiangiogenic activity
US20030105025A1 (en) * 2001-10-31 2003-06-05 Fortuna Haviv Tri-and tetrapeptides having antiangiogenic activity
US20030119746A1 (en) * 2001-10-31 2003-06-26 Fortuna Haviv Hepta-and octapeptides having antiangiogenic activity
US20030125259A1 (en) 2001-10-31 2003-07-03 Fortuna Haviv Octa- and nonapeptides having antiangiogenic activity
WO2003037266A2 (en) * 2001-10-31 2003-05-08 Abbott Laboratories Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity
US7122625B2 (en) 2001-10-31 2006-10-17 Abbott Laboratories Hexa-, hepta-, and octapeptides having antiangiogenic activity
US7037897B2 (en) 2001-10-31 2006-05-02 Abbott Laboratories TRI-, TETRA-, and penta-peptides having antiangiogenic activity
US7067490B2 (en) 2001-10-31 2006-06-27 Abbott Laboratories Hepta-, Octa-and nonapeptides having antiangiogenic activity
CN1652810A (zh) 2002-03-22 2005-08-10 Gpc生物科技股份公司 免疫抑制化合物、方法及其相关应用
US7432245B2 (en) 2002-06-07 2008-10-07 Abbott Laboratories Inc. Pharmaceutical formulation comprising a peptide angiogenesis inhibitor
US20030228365A1 (en) * 2002-06-07 2003-12-11 Fortuna Haviv Pharmaceutical formulation
JP5167473B2 (ja) 2005-03-03 2013-03-21 コヴェックス・テクノロジーズ・アイルランド・リミテッド 抗血管新生化合物
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
JP2007255910A (ja) * 2006-03-20 2007-10-04 Hokkaido Univ Ｎｍｒシグナルの帰属方法
JO3324B1 (ar) 2006-04-21 2019-03-13 Amgen Inc مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية
WO2008003013A2 (en) * 2006-06-29 2008-01-03 Abbott Laboratories Antitumorigenic drug combination comprising an hdac inhibitor and a tsp-1 peptidomimetic
CN104004057B (zh) * 2013-02-25 2016-08-24 上海市第一人民医院 一类抑制新生血管的小肽及其应用
CN107778355B (zh) * 2016-08-25 2021-04-20 成都圣诺生物制药有限公司 一种合成西曲瑞克的方法
WO2023033016A1 (ja) * 2021-09-01 2023-03-09 積水メディカル株式会社 アルギニン誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200397A (en) * 1990-02-22 1993-04-06 W. R. Grace & Co.-Conn. Use of peptide analogs of thrombospondin for the inhibition of angiogenic activity
WO1993016716A1 (en) * 1992-02-24 1993-09-02 Northwestern University Method and composition for inhibiting angiogenesis
IL126626A0 (en) * 1996-05-03 1999-08-17 Abbott Lab Novel antiangiogenic peptides polynucleotides encoding same and methods for inhibiting angiogenesis
PT918795E (pt) * 1997-03-17 2005-02-28 Abbott Lab Droga antiangiogenica para tratar cancro artrite e retinopatia

Also Published As

Publication number Publication date
BG65065B1 (bg) 2007-01-31
TWI247748B (en) 2006-01-21
PL344415A1 (en) 2001-11-05
JP3795906B2 (ja) 2006-07-12
ES2307337T3 (es) 2008-11-16
KR100447696B1 (ko) 2004-09-08
HUP0102579A2 (hu) 2002-01-28
NO20005890D0 (no) 2000-11-21
JP2006232840A (ja) 2006-09-07
SI1078002T1 (sl) 2008-10-31
CN1311796A (zh) 2001-09-05
NZ507912A (en) 2002-10-25
EP1078002B1 (en) 2008-05-21
BR9910639A (pt) 2002-01-15
PL200471B1 (pl) 2009-01-30
CA2329250A1 (en) 1999-12-02
DE69938782D1 (de) 2008-07-03
HUP0102579A3 (en) 2002-02-28
CA2329250C (en) 2012-03-27
SK17632000A3 (sk) 2001-07-10
NO20005890L (no) 2001-01-12
JP2002516342A (ja) 2002-06-04
JP2006001923A (ja) 2006-01-05
AU4407599A (en) 1999-12-13
PT1078002E (pt) 2008-09-02
TR200003442T2 (tr) 2001-03-21
ATE396204T1 (de) 2008-06-15
EP1078002A1 (en) 2001-02-28
SK286554B6 (sk) 2008-12-05
WO1999061476A1 (en) 1999-12-02
CZ20004327A3 (cs) 2001-08-15
KR20010025093A (ko) 2001-03-26
NO326871B1 (no) 2009-03-09
AR018371A1 (es) 2001-11-14
AU764277B2 (en) 2003-08-14
CZ299639B6 (cs) 2008-10-01
HK1037376A1 (en) 2002-02-08
CO5080726A1 (es) 2001-09-25
BG105064A (en) 2001-08-31
JP3753612B2 (ja) 2006-03-08

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