DE69415682D1 - Neue urethan enthaltende aminosteroid verbindungen - Google Patents

Neue urethan enthaltende aminosteroid verbindungen

Info

Publication number
DE69415682D1
DE69415682D1 DE69415682T DE69415682T DE69415682D1 DE 69415682 D1 DE69415682 D1 DE 69415682D1 DE 69415682 T DE69415682 T DE 69415682T DE 69415682 T DE69415682 T DE 69415682T DE 69415682 D1 DE69415682 D1 DE 69415682D1
Authority
DE
Germany
Prior art keywords
urethanic
new
aminosteroid compounds
compounds
aminosteroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69415682T
Other languages
English (en)
Other versions
DE69415682T2 (de
Inventor
Chia-Nien Yu
Gilles Genain
Rachel Boujo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of DE69415682D1 publication Critical patent/DE69415682D1/de
Publication of DE69415682T2 publication Critical patent/DE69415682T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011—Unsubstituted amino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69415682T 1993-09-24 1994-09-23 Neue urethan enthaltende aminosteroid verbindungen Expired - Fee Related DE69415682T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/126,293 US5922703A (en) 1993-09-24 1993-09-24 Urethane-containing aminosteroid compounds
PCT/US1994/010780 WO1995008559A1 (en) 1993-09-24 1994-09-23 Novel urethane-containing aminosteroid compounds

Publications (2)

Publication Number Publication Date
DE69415682D1 true DE69415682D1 (de) 1999-02-11
DE69415682T2 DE69415682T2 (de) 1999-07-22

Family

ID=22424049

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69415682T Expired - Fee Related DE69415682T2 (de) 1993-09-24 1994-09-23 Neue urethan enthaltende aminosteroid verbindungen

Country Status (17)

Country Link
US (1) US5922703A (de)
EP (1) EP0720617B1 (de)
JP (1) JPH09502984A (de)
KR (1) KR960704913A (de)
CN (1) CN1135221A (de)
AT (1) ATE175205T1 (de)
AU (1) AU690926B2 (de)
BR (1) BR9407654A (de)
CA (1) CA2172495A1 (de)
CZ (1) CZ86296A3 (de)
DE (1) DE69415682T2 (de)
DK (1) DK0720617T3 (de)
ES (1) ES2126155T3 (de)
HU (1) HUT74169A (de)
NO (1) NO307757B1 (de)
PL (1) PL313622A1 (de)
WO (1) WO1995008559A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0721459B1 (de) * 1993-09-24 2000-05-31 The Procter & Gamble Company Neue oligosaccharid-enthaltende 14-aminosteroidverbindungen und neuer diastereoselektive aminosteroid verfahren chemie
US6339716B1 (en) * 1999-09-24 2002-01-15 Bioenergy Inc. Method for determining viability of a myocardial segment
DE60045751D1 (de) 1999-09-30 2011-04-28 Harbor Biosciences Inc Therapeutische Behandlung androgenrezeptorbedingter Leiden
US6703370B1 (en) 1999-10-27 2004-03-09 Bioenergy, Inc. Use of ribose to treat fibromyalgia
ES2857626T3 (es) 2010-01-15 2021-09-29 Suzhou Neupharma Co Ltd Ciertas entidades químicas, composiciones y métodos
US9018197B2 (en) 2010-08-28 2015-04-28 Suzhou Neupharma Co. Ltd. Tetradecahydro-1H-cyclopenta[a]phenanthrene compounds, compositions, and related methods of use
EP2670763B1 (de) * 2011-02-02 2018-08-01 Suzhou Neupharma Co., Ltd Bestimmte chemische stoffe, zusammensetzungen und verfahren
WO2013165924A1 (en) 2012-04-29 2013-11-07 Neupharma, Inc. Certain chemical entities, compositions, and methods

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
FR2464270A1 (fr) * 1979-08-31 1981-03-06 Nativelle Sa Ets Nouveaux derives d'amino-14 steroides, et procede pour leur preparation
DD154899A1 (de) * 1980-12-01 1982-04-28 Rudolf Megges Verfahren zur herstellung von cardenolid-und bufadienolid-14 beta-o-urethanen
ES524614A0 (es) * 1982-08-12 1984-05-01 Nativelle Sa Ets Procedimiento de preparacion de nuevos amino-14 esteroides.
NZ205293A (en) * 1982-08-20 1986-12-05 Nativelle Sa Ets 14-aminosteroids and pharmaceutical compositions
ES524796A0 (es) * 1982-08-20 1984-05-01 Nativelle Sa Ets Procedimiento de preparacion de nuevos derivos de amino-14 esteroides
DD256134A1 (de) * 1985-06-06 1988-04-27 Akad Wissenschaften Ddr Verfahren zur herstellung von derivaten von cardenoliden und cardenolidanalogen verbindungen
US5175281A (en) * 1985-09-12 1992-12-29 The Upjohn Company Pharmaceutically active pyrimidinylpiperazinylsterioids
GB8600490D0 (en) * 1986-01-09 1986-02-12 Erba Farmitalia Aminoglycoside norcholanic acid lactams
FR2621316B1 (fr) * 1987-10-02 1991-06-21 Nativelle Sa Ets Nouveaux esters d'acide androstane 17-carboxylique, procede pour leur preparation, et medicament les contenant
US5144017A (en) * 1988-07-13 1992-09-01 University Of Manitoba Compounds that bind to digitalis receptor
FR2642973A1 (fr) * 1989-02-03 1990-08-17 Cote Ivoire Ministere Rech Sc Composition medicamenteuse renfermant comme principe actif un derive glucidique dioxymethyle de la strophanthidine
EP0530224A1 (de) * 1990-05-07 1993-03-10 The Board Of Regents Of The University Of Washington Neue steroid-glykosiden, verwendbar bei der frühen entdeckung der hypertonie
JPH0429089A (ja) * 1990-05-25 1992-01-31 Toshiba Corp 燃料集合体
KR960704915A (ko) * 1993-09-24 1996-10-09 제이코버스 코넬리스 레이서 신규한 데옥시 및 산소 치환된 당 함유 14- 아미노스테로이드 화합물 (novel deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds)
EP0721459B1 (de) * 1993-09-24 2000-05-31 The Procter & Gamble Company Neue oligosaccharid-enthaltende 14-aminosteroidverbindungen und neuer diastereoselektive aminosteroid verfahren chemie

Also Published As

Publication number Publication date
JPH09502984A (ja) 1997-03-25
ES2126155T3 (es) 1999-03-16
DE69415682T2 (de) 1999-07-22
AU7877994A (en) 1995-04-10
PL313622A1 (en) 1996-07-08
NO307757B1 (no) 2000-05-22
US5922703A (en) 1999-07-13
ATE175205T1 (de) 1999-01-15
EP0720617A1 (de) 1996-07-10
CA2172495A1 (en) 1995-03-30
EP0720617B1 (de) 1998-12-30
DK0720617T3 (da) 1999-08-30
HUT74169A (en) 1996-11-28
CZ86296A3 (en) 1996-12-11
KR960704913A (ko) 1996-10-09
NO961168L (no) 1996-05-23
AU690926B2 (en) 1998-05-07
WO1995008559A1 (en) 1995-03-30
BR9407654A (pt) 1997-01-28
HU9600736D0 (en) 1996-05-28
CN1135221A (zh) 1996-11-06
NO961168D0 (no) 1996-03-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee