MX9600165A - 3-alcoxicarbonil-tiadiazinonas, proceso para su preparacion y composiciones farmaceuticas que las contienen. - Google Patents

3-alcoxicarbonil-tiadiazinonas, proceso para su preparacion y composiciones farmaceuticas que las contienen.

Info

Publication number
MX9600165A
MX9600165A MX9600165A MX9600165A MX9600165A MX 9600165 A MX9600165 A MX 9600165A MX 9600165 A MX9600165 A MX 9600165A MX 9600165 A MX9600165 A MX 9600165A MX 9600165 A MX9600165 A MX 9600165A
Authority
MX
Mexico
Prior art keywords
alkoxycarbonylthiadiazinonas
preparation
pharmaceutical compositions
compositions containing
inotropical
Prior art date
Application number
MX9600165A
Other languages
English (en)
Inventor
Rochus Jonas
Inge Lues
Norbert Beier
Klaus-Otto Minck
Original Assignee
Merck Patent Gmbh
Haftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh, Haftung filed Critical Merck Patent Gmbh
Publication of MX9600165A publication Critical patent/MX9600165A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

En la presente invencion se describen 3-alcoxicarboniltiadiazinonas de la formula I: y sales fisiologicamente inobjetables de las mismas, en la cual R1, R2, R3, R4, R5, Q y n tienen los significados dados en la reivindicacion 1, las cuales exhiben una accion positivamente inotropica y se pueden emplear para la terapia de insuficiencia cardiaca.
MX9600165A 1995-01-11 1996-01-09 3-alcoxicarbonil-tiadiazinonas, proceso para su preparacion y composiciones farmaceuticas que las contienen. MX9600165A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19500558A DE19500558A1 (de) 1995-01-11 1995-01-11 3-Alkoxycarbonyl-thiadiazinone

Publications (1)

Publication Number Publication Date
MX9600165A true MX9600165A (es) 1997-01-31

Family

ID=7751240

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9600165A MX9600165A (es) 1995-01-11 1996-01-09 3-alcoxicarbonil-tiadiazinonas, proceso para su preparacion y composiciones farmaceuticas que las contienen.

Country Status (24)

Country Link
US (1) US5705497A (es)
EP (1) EP0721950B1 (es)
JP (1) JP4025377B2 (es)
KR (1) KR100399541B1 (es)
CN (1) CN1055691C (es)
AT (1) ATE165828T1 (es)
AU (1) AU704493B2 (es)
CA (1) CA2166854A1 (es)
CZ (1) CZ292094B6 (es)
DE (2) DE19500558A1 (es)
DK (1) DK0721950T3 (es)
ES (1) ES2120251T3 (es)
GR (1) GR3027566T3 (es)
HK (1) HK1010194A1 (es)
HU (1) HUP9600061A3 (es)
MX (1) MX9600165A (es)
NO (1) NO306300B1 (es)
PL (1) PL183011B1 (es)
RU (1) RU2162087C2 (es)
SI (1) SI0721950T1 (es)
SK (1) SK280532B6 (es)
TW (1) TW407157B (es)
UA (1) UA44249C2 (es)
ZA (1) ZA96177B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
DE19929785A1 (de) 1999-06-29 2001-01-04 Bayer Ag Tetrahydrochinolinyl-6-methyldihydrothiadiazinon-Derivate und ihre Verwendung
JP6543697B2 (ja) * 2014-08-15 2019-07-10 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ２，２，２−トリフルオロエチル−チアジアジン類
CN112500353B (zh) * 2020-12-08 2022-11-25 北京晨光同创医药研究院有限公司 一种左西孟旦的前药化合物、制备方法及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU614965B2 (en) * 1987-06-06 1991-09-19 Merck Patent Gesellschaft Mit Beschrankter Haftung Thiadiazinones
DE4041074A1 (de) * 1990-12-21 1992-06-25 Merck Patent Gmbh Thiadiazinonderivate
DE4129062A1 (de) * 1991-09-02 1993-03-04 Merck Patent Gmbh Verfahren zur enantiomerentrennung von 5-hetaryl-1,3,4-thiadiazinonen
DE4134893A1 (de) * 1991-10-23 1993-04-29 Merck Patent Gmbh Thiadiazinone
DE4223537A1 (de) * 1992-07-17 1994-01-20 Merck Patent Gmbh Thiadiazinone
DE4310699A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Thiadiazinone

Also Published As

Publication number Publication date
KR960029331A (ko) 1996-08-17
CN1135484A (zh) 1996-11-13
DE59600173D1 (de) 1998-06-10
HUP9600061A2 (en) 1997-10-28
ZA96177B (en) 1996-07-30
PL183011B1 (pl) 2002-05-31
CZ8096A3 (en) 1996-07-17
RU2162087C2 (ru) 2001-01-20
AU704493B2 (en) 1999-04-22
GR3027566T3 (en) 1998-11-30
EP0721950A3 (es) 1996-07-24
EP0721950B1 (de) 1998-05-06
JPH08253478A (ja) 1996-10-01
CA2166854A1 (en) 1996-07-12
ATE165828T1 (de) 1998-05-15
KR100399541B1 (ko) 2003-12-31
CZ292094B6 (cs) 2003-07-16
NO306300B1 (no) 1999-10-18
SK165295A3 (en) 1996-08-07
SK280532B6 (sk) 2000-03-13
NO960112L (no) 1996-07-12
ES2120251T3 (es) 1998-10-16
HK1010194A1 (en) 1999-06-17
PL312240A1 (en) 1996-07-22
NO960112D0 (no) 1996-01-10
CN1055691C (zh) 2000-08-23
TW407157B (en) 2000-10-01
DK0721950T3 (da) 1999-02-15
AU4082696A (en) 1996-07-18
DE19500558A1 (de) 1996-07-18
SI0721950T1 (en) 1998-10-31
HUP9600061A3 (en) 1998-04-28
US5705497A (en) 1998-01-06
JP4025377B2 (ja) 2007-12-19
EP0721950A2 (de) 1996-07-17
UA44249C2 (uk) 2002-02-15

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MX9600165A (es) 3-alcoxicarbonil-tiadiazinonas, proceso para su preparacion y composiciones farmaceuticas que las contienen.