ATE256145T1 - Peptid analoge, die einen siebengliedrigen lactamring enthalten - Google Patents

Peptid analoge, die einen siebengliedrigen lactamring enthalten

Info

Publication number
ATE256145T1
ATE256145T1 AT97945015T AT97945015T ATE256145T1 AT E256145 T1 ATE256145 T1 AT E256145T1 AT 97945015 T AT97945015 T AT 97945015T AT 97945015 T AT97945015 T AT 97945015T AT E256145 T1 ATE256145 T1 AT E256145T1
Authority
AT
Austria
Prior art keywords
peptide derivatives
membed
lactam ring
peptide analogues
analogues containing
Prior art date
Application number
AT97945015T
Other languages
English (en)
Inventor
Richard William Arthur Luke
Ronald Cotton
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE256145T1 publication Critical patent/ATE256145T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/81Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97945015T 1996-10-19 1997-10-14 Peptid analoge, die einen siebengliedrigen lactamring enthalten ATE256145T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9621836.7A GB9621836D0 (en) 1996-10-19 1996-10-19 Peptide compounds
PCT/GB1997/002837 WO1998017680A1 (en) 1996-10-19 1997-10-14 Peptide analogues containing a 7-membered lactam ring

Publications (1)

Publication Number Publication Date
ATE256145T1 true ATE256145T1 (de) 2003-12-15

Family

ID=10801703

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97945015T ATE256145T1 (de) 1996-10-19 1997-10-14 Peptid analoge, die einen siebengliedrigen lactamring enthalten

Country Status (10)

Country Link
US (1) US6207644B1 (de)
EP (1) EP0932618B1 (de)
JP (1) JP2001508036A (de)
AT (1) ATE256145T1 (de)
AU (1) AU4633097A (de)
DE (1) DE69726743T2 (de)
GB (1) GB9621836D0 (de)
TW (1) TW492868B (de)
WO (1) WO1998017680A1 (de)
ZA (1) ZA979338B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000512277A (ja) 1996-06-07 2000-09-19 ゼネカ・リミテッド ペプチド誘導体
JP2003503119A (ja) 1999-06-25 2003-01-28 エモリ ユニバーシティ 迷走神経刺激用機器及び方法
TW200502221A (en) 2002-10-03 2005-01-16 Astrazeneca Ab Novel lactams and uses thereof
ATE533500T1 (de) * 2003-02-14 2011-12-15 Provid Pharmaceuticals Inc Hemmer der antigenpräsentation über mhc-klasse-ii-moleküle und verwendungsverfahren dafür
US7342007B2 (en) 2003-03-14 2008-03-11 Astrazeneca Ab Lactams and uses thereof
WO2005053702A2 (en) * 2003-12-01 2005-06-16 Cambridge University Technical Services Limited Anti-inflammatory agents
WO2009073168A1 (en) * 2007-12-03 2009-06-11 Provid Pharmaceuticals, Inc. Inhibitors of antigen presentation by mhc class ii molecules and methods of use thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474778A (en) * 1983-11-09 1984-10-02 E. R. Squibb & Sons, Inc. Lactam containing compounds, their pharmaceutical compositions and method of use
DE3711335A1 (de) 1987-04-03 1988-10-20 Merck Patent Gmbh Aminosaeurederivate
US5223485A (en) 1989-01-31 1993-06-29 Abbott Laboratories Anaphylatoxin-receptor ligands
AU8305491A (en) 1990-08-01 1992-03-02 Cytel Corporation Novel immunosuppressant peptides
DE4034829A1 (de) 1990-11-02 1992-05-07 Merck Patent Gmbh Cyclopeptide
AU2468392A (en) 1991-08-29 1993-04-05 Cytel Corporation Novel immunosuppressants
ES2122145T3 (es) 1993-06-04 1998-12-16 Vertex Pharma Fosfiniloximetil-cetonas peptidicas como inhibidores de la enzima convertida de la interleuquina-1 beta.
JP3926839B2 (ja) 1993-09-14 2007-06-06 エピミューン,インコーポレイティド 万能dr−結合性ペプチドを用いる免疫応答の改変
AU2238395A (en) 1994-04-01 1995-10-23 Immulogic Pharmaceutical Corporation Haptenated peptides and uses thereof
CA2215720A1 (en) 1995-03-24 1996-10-03 Molecumetics, Ltd. .beta.-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins
AU7604196A (en) 1995-10-30 1997-05-22 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5817757A (en) * 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
US5840835A (en) * 1995-10-30 1998-11-24 Merck & Co., Inc. Inhibitors of peptide binding to MHC class II proteins
US5719296A (en) 1995-10-30 1998-02-17 Merck & Co., Inc. Pseudopeptide lactam inhibitors of peptide binding to MHC class II proteins
GB9702377D0 (en) 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives

Also Published As

Publication number Publication date
ZA979338B (en) 1998-04-20
US6207644B1 (en) 2001-03-27
DE69726743D1 (de) 2004-01-22
TW492868B (en) 2002-07-01
AU4633097A (en) 1998-05-15
EP0932618A1 (de) 1999-08-04
EP0932618B1 (de) 2003-12-10
JP2001508036A (ja) 2001-06-19
DE69726743T2 (de) 2004-10-14
GB9621836D0 (en) 1996-12-11
WO1998017680A1 (en) 1998-04-30

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties