CY1106174T1 - Ενωσεις μειγματων μεταλλων χωρις αλουμινιο ως συνδετικες ουσιες φωσφορικων - Google Patents

Ενωσεις μειγματων μεταλλων χωρις αλουμινιο ως συνδετικες ουσιες φωσφορικων

Info

Publication number
CY1106174T1
CY1106174T1 CY20061101402T CY061101402T CY1106174T1 CY 1106174 T1 CY1106174 T1 CY 1106174T1 CY 20061101402 T CY20061101402 T CY 20061101402T CY 061101402 T CY061101402 T CY 061101402T CY 1106174 T1 CY1106174 T1 CY 1106174T1
Authority
CY
Cyprus
Prior art keywords
phosphate binding
aluminum
metal compounds
binding agents
mixed metal
Prior art date
Application number
CY20061101402T
Other languages
English (en)
Inventor
Norman Bryson Roberts
Maurice Webb
Benjamin Joseph Rankin
Original Assignee
Ineos Healthcare Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ineos Healthcare Limited filed Critical Ineos Healthcare Limited
Publication of CY1106174T1 publication Critical patent/CY1106174T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F11/00—Compounds of calcium, strontium, or barium
    • C01F11/18—Carbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/244—Lanthanides; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F5/00—Compounds of magnesium
    • C01F5/24—Magnesium carbonates
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G49/00—Compounds of iron
    • C01G49/009—Compounds containing, besides iron, two or more other elements, with the exception of oxygen or hydrogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Geology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Catalysts (AREA)
  • External Artificial Organs (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Paints Or Removers (AREA)
  • Lubricants (AREA)
  • Dental Preparations (AREA)

Abstract

Μια ένωση μίγματος μετάλλων για φαρμακευτική χρήση χωρίς αλουμίνιο και η οποία έχει μια ικανότητα σύνδεσης φωσφορικών τουλάχιστον 30% κατά βάρος του συνολικού βάρους των φωσφορικών που υπάρχουν, με pΗ από 2-8. Η ένωση είναι ιδιαίτερα χρήσιμη για τη θεραπεία της υπερφωσφαταιμίας. Τα μέταλλα είναι κατά προτίμηση σίδηρος (III) και τουλάχιστον ένα εκ των ασβεστίου, μαγνησίου, λανθανίου και δημητρίου. Ένα μεταλλικό θειικό άλας για φαρμακευτική χρήση επιλέγεται από τουλάχιστον μία θειική ένωση του ασβεστίου, του λανθανίου και του δημητρίου και έχει μια ικανότητα σύνδεσης φωσφορικών τουλάχιστον 30% κατά βάρος των συνολικών φωσφορικών που υπάρχουν, με pΗ που κυμαίνεται από 2-8.
CY20061101402T 1997-09-19 2006-09-28 Ενωσεις μειγματων μεταλλων χωρις αλουμινιο ως συνδετικες ουσιες φωσφορικων CY1106174T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9720061.2A GB9720061D0 (en) 1997-09-19 1997-09-19 Metal compounds as phosphate binders
PCT/GB1998/002834 WO1999015189A1 (en) 1997-09-19 1998-09-18 Metal compounds, mixed or sulphated, as phosphate binders

Publications (1)

Publication Number Publication Date
CY1106174T1 true CY1106174T1 (el) 2011-06-08

Family

ID=10819414

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20061101402T CY1106174T1 (el) 1997-09-19 2006-09-28 Ενωσεις μειγματων μεταλλων χωρις αλουμινιο ως συνδετικες ουσιες φωσφορικων
CY20111100186T CY1111199T1 (el) 1997-09-19 2011-02-14 Μικτες ενωσεων ή θειϊκες μεταλλικες ενωσεις, ως συνδετικες ουσιες φωσφορικων

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY20111100186T CY1111199T1 (el) 1997-09-19 2011-02-14 Μικτες ενωσεων ή θειϊκες μεταλλικες ενωσεις, ως συνδετικες ουσιες φωσφορικων

Country Status (20)

Country Link
US (4) US6926912B1 (el)
EP (2) EP1759704B1 (el)
JP (3) JP4149659B2 (el)
KR (2) KR100997504B1 (el)
CN (2) CN1911245B (el)
AT (2) ATE489958T1 (el)
AU (1) AU9173398A (el)
BR (1) BR9812223A (el)
CA (1) CA2303820C (el)
CY (2) CY1106174T1 (el)
DE (2) DE69842028D1 (el)
DK (2) DK1759704T3 (el)
ES (2) ES2355925T3 (el)
GB (1) GB9720061D0 (el)
HK (1) HK1098390A1 (el)
HU (2) HU227666B1 (el)
NZ (1) NZ503136A (el)
PL (1) PL194211B1 (el)
PT (2) PT1759704E (el)
WO (1) WO1999015189A1 (el)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
DE19917705C1 (de) * 1999-04-20 2000-12-28 Vitasyn Gmbh Mittel zur Therapie von Hyperphosphatämie
US20060083791A1 (en) 2002-05-24 2006-04-20 Moerck Rudi E Rare earth metal compounds methods of making, and methods of using the same
US20040161474A1 (en) * 2002-05-24 2004-08-19 Moerck Rudi E. Rare earth metal compounds methods of making, and methods of using the same
CN100526219C (zh) * 2002-08-14 2009-08-12 爱尔达纳米公司 稀土金属化合物、其制造方法及其使用方法
EP2194028B1 (en) * 2002-08-14 2022-01-26 Unicycive Therapeutics, Inc. Rare earth metal compounds, methods of making, and methods of using the same
HUE024906T2 (en) * 2003-08-26 2016-02-29 Shire Biopharmaceuticals Holdings Ireland Ltd Pharmaceutical composition containing lanthanum compounds
DE102004031181A1 (de) * 2004-06-28 2006-01-19 Vifor (International) Ag Phosphatadsorbens
CA2574450C (en) * 2004-07-27 2011-07-19 Shire Pharmaceuticals, Inc. Method of treating hyperphosphataemia using lanthanum hydroxycarbonate
JP2008526771A (ja) * 2004-12-30 2008-07-24 ジェンザイム コーポレーション 高リン酸血症のための亜鉛含有処置
GB0502787D0 (en) * 2005-02-10 2005-03-16 Ineos Silicas Ltd Pharmaceuticlly active compounds, their manufacture, compositions containing them and their use
WO2006132321A1 (ja) * 2005-06-09 2006-12-14 J-Pharma Co., Ltd. リン障害予防改善治療剤、飲食品又は薬品中のリン酸イオンを吸着するための経口剤及びそれらの製造方法
US8986669B2 (en) 2005-09-02 2015-03-24 Genzyme Corporation Method for removing phosphate and polymer used therefore
JP2009514966A (ja) * 2005-11-08 2009-04-09 ジェンザイム・コーポレーション 高リン血症のためのマグネシウム含有重合体
GB0601899D0 (en) * 2006-01-31 2006-03-08 Ineos Silicas Ltd Compositions
AU2016213745B2 (en) * 2006-01-31 2019-03-14 Cytochroma Development Inc. Granular Material Comprising Water-Insoluble Inorganic Phosphate Binders
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
CN101505766B (zh) * 2006-06-29 2011-10-05 J制药股份有限公司 磷障碍预防改善治疗剂、用于吸附食品或药品中的磷酸离子的口服剂及它们的制造方法
EP2043627A2 (en) * 2006-07-05 2009-04-08 Genzyme Corporation Iron(ii)-containing treatments for hyperphosphatemia
ES2526171T3 (es) 2006-12-14 2015-01-07 Novartis Ag Adsorbente de fosfato a base de hierro (III)-carbohidratos
EP1932807A1 (en) * 2006-12-14 2008-06-18 Novartis AG Inorganic compounds
JP4513819B2 (ja) 2007-03-19 2010-07-28 株式会社日立製作所 映像変換装置、映像表示装置、映像変換方法
GB0714670D0 (en) * 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) * 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
EP2403506A1 (en) * 2009-03-02 2012-01-11 Vifor (International) Ag Phosphate adsorbent
CA2756942C (en) * 2009-04-10 2019-01-08 Cypress Pharmaceuticals, Inc. Phosphate-binding magnesium salts and uses thereof
US8247000B2 (en) 2009-04-10 2012-08-21 Cypress Pharmaceutical, Inc. Phosphate-binding magnesium salts and uses thereof
JP5336932B2 (ja) * 2009-05-29 2013-11-06 株式会社東芝 水質浄化材料、水質浄化方法、リン酸肥料前駆体及びリン酸肥料前駆体の製造方法
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
DE102009045899B4 (de) * 2009-10-21 2012-03-22 Freie Universität Berlin Bismuthaltige Zusammensetzung zur Reduzierung der Phosphatkonzentration in Flüssigkeiten
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
US8961917B2 (en) 2010-05-12 2015-02-24 Spectrum Pharmaceuticals, Inc. Lanthanum carbonate hydroxide, lanthanum oxycarbonate and methods of their manufacture and use
DE102011112898A1 (de) 2011-09-08 2013-03-14 Charité - Universitätsmedizin Berlin Nanopartikuläres Phosphatadsorbens basierend auf Maghämit oder Maghämit/Magnetit, dessen Herstellung und Verwendungen
US9394318B2 (en) 2012-11-30 2016-07-19 Cypress Pharmaceuticals, Inc. Crystal polymorph of magnesium glycinate dihydrate and process for its preparation
AU2019363816A1 (en) 2018-10-25 2021-05-13 Eirgen Pharma Ltd. Methods of treatment with mixed metal compounds
CN112816575A (zh) * 2020-12-29 2021-05-18 平光制药股份有限公司 一种碳酸司维拉姆的磷酸盐结合力的分析方法
CN115024495B (zh) * 2022-06-27 2024-03-22 北京金康普食品科技有限公司 改善肾病患者钙磷代谢的营养组合物及其应用

Family Cites Families (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2222924A (en) * 1936-12-10 1940-11-26 Degussa Preparation of cerium sulphate
US2812344A (en) * 1956-02-13 1957-11-05 Ortho Pharma Corp Ferrous calcium citrate complex
FR1214473A (fr) * 1959-01-07 1960-04-08 Procédé de préparation d'un catalyseur à base d'hydroxyde de cérium
BE590192A (el) 1959-04-27
US3395211A (en) * 1965-12-10 1968-07-30 Carter Wallace Tableting process
US3539306A (en) * 1966-07-25 1970-11-10 Kyowa Chem Ind Co Ltd Process for the preparation of hydrotalcite
US3879523A (en) * 1969-12-12 1975-04-22 Kyowa Chem Ind Co Ltd Composite metal hydroxides
SU414849A1 (ru) * 1971-05-21 1977-09-05 Харьковский домостроительный комбинат Бетонна смесь
BE792032A (fr) 1971-12-23 1973-03-16 Baxter Laboratories Inc Dispositif de transfert de masse ayant une membrame semi-permeable disposee en spirale et presentant un faible volume de fluide
NL174720C (nl) * 1973-12-13 1984-08-01 Philips Nv Beeldweergeefcel en methode voor de vervaardiging van een vloeibaar kristallijn p-n.butyl-p'-alkoxyazobenzeen.
JPS5417518Y2 (el) 1975-06-05 1979-07-05
PL110490B1 (en) 1976-05-19 1980-07-31 Politechnika Poznanska Agent for preparing hydrophobic solutions extracting ions of non ferrous metals from aqueous solutions also a method of producing an agent for preparing hydrophobic solutions extracting ions of non ferrous metals
DE2642984C3 (de) 1976-09-24 1980-01-24 Maschinenfabrik Karl Brieden & Co, 4630 Bochum Blasversatzleitung mit stirnseitigem Austrag
FR2435442A1 (fr) 1978-09-07 1980-04-04 Om Lab Sa Silicate de magnesium et d'aluminium synthetique, procede de fabrication de celui-ci et compositions pharmaceutiques comprenant celui-ci
US4192900A (en) 1978-10-12 1980-03-11 Merck & Co., Inc. Texturized starch products
DE2845326C2 (de) * 1978-10-18 1985-05-23 Beiersdorf Ag, 2000 Hamburg Verwendung einer spezifischen mikrodispersen, amorphen, porösen Kieselsäure zur Herstellung von Digoxin enthaltenden Tabletten mit stark beschleunigter Wirkstoff-Freisetzung
DE3039997A1 (de) 1980-10-23 1982-06-03 Bayer Ag, 5090 Leverkusen Phosphonohydroxyacetonitril, ein verfahren zu seiner herstellung und seine verwendung als zwischenprodukt fuer die herstellung von arzneimitteln
US4351814A (en) * 1980-12-18 1982-09-28 Kyowa Chemical Industry Co., Ltd. Hydrotalcites having a hexagonal needle-like crystal structure and process for production thereof
JPS57156419A (en) * 1981-03-24 1982-09-27 Kyowa Chem Ind Co Ltd Remedy for sideropenia
US4514389A (en) 1981-05-06 1985-04-30 Kyowa Chemical Industry Co. Ltd. Gastric antacid and method for controlling pH of gastric juice
CA1198674A (en) 1981-11-23 1985-12-31 Rorer International (Holdings) Inc. Antacid compositions
US4458026A (en) * 1982-06-02 1984-07-03 Union Carbide Corporation Catalysts for aldol condensations
US4582705A (en) * 1982-07-12 1986-04-15 Leonard Primes Composition for detoxification
DE3228231A1 (de) * 1982-07-28 1984-02-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München Arzneimittel, calciummischsalze von polymeren, anionischen carbonsaeuren und/oder schwefelsaeureestern, verfahren zu ihrer herstellung und ihre verwendung
JPS606619A (ja) * 1983-06-27 1985-01-14 Kyowa Chem Ind Co Ltd 鉄分欠乏症処置剤及びその製法
GB8317595D0 (en) 1983-06-29 1983-08-03 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
US4609543A (en) * 1983-11-14 1986-09-02 Nabisco Brands, Inc. Soft homogeneous antacid tablet
JPS60131604A (ja) * 1983-12-20 1985-07-13 Victor Co Of Japan Ltd 磁気記録再生素子
DE3346943A1 (de) 1983-12-24 1985-07-04 Bayer Ag, 5090 Leverkusen Herstellung von hydrotalcit mit verbesserten eigenschaften
DE3402878A1 (de) * 1984-01-27 1985-08-01 Algina AG, Zug Arzneimittel und die verwendung schwerloeslicher calcium- und/oder magnesiumverbindungen als arzneimittel
FR2559755A1 (fr) * 1984-02-20 1985-08-23 Rhone Poulenc Spec Chim Oxyde cerique a nouvelles caracteristiques morphologiques et son procede d'obtention
JPS6136222A (ja) * 1984-07-26 1986-02-20 Chugai Pharmaceut Co Ltd 高リン酸血症治療剤
US4566986A (en) * 1984-08-31 1986-01-28 Waldmann John J Flocculating agents and processes for making them
DE3520108A1 (de) * 1985-06-05 1986-12-11 Varta Batterie Ag, 3000 Hannover Positive sammlerelektrode fuer akkumulatoren mit alkalischem elektrolyten
JPH06705B2 (ja) * 1985-12-19 1994-01-05 旭化成工業株式会社 リン酸イオンの固定化剤
US6749864B2 (en) 1986-02-13 2004-06-15 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
US4871392A (en) 1986-05-23 1989-10-03 American Cyanamid Company Aqueous suspension concentrate compositions of pendimethalin
US4801454A (en) 1986-07-17 1989-01-31 The Proctor & Gamble Company Processes for making colored pharmaceutical compositions
EP0300853B1 (fr) * 1987-06-29 1991-09-18 Rhone-Poulenc Chimie Procédé d'obtention d'un oxyde cérique
US4994283A (en) * 1987-07-02 1991-02-19 The Procter & Gamble Company Iron-calcium mineral supplements with enhanced bioavailability
US4786510A (en) * 1987-07-02 1988-11-22 The Procter & Gamble Company Calcium-iron mineral supplements
DE3801382A1 (de) * 1988-01-19 1989-08-03 Ebner Anlagen & Apparate Verfahren und anlage zur umwandlung von natriumsulfat in natriumhydroxid
ATE108996T1 (de) * 1988-02-25 1994-08-15 Brocades Pharma Bv Verfahren zur herstellung eines pharmazeutischen granulats.
HU201880B (en) 1988-06-21 1991-01-28 Semmelweis Orvostudomanyi Egye Process for producing pharmaceutical compositions for profilacting and treating renal diseases and for diminishing frequency of extracorporalis dialysis
GB8826333D0 (en) 1988-11-10 1988-12-14 Unilever Plc Oral compositions
GB8902581D0 (en) 1989-02-06 1989-03-22 Telephone Cables Ltd Optical fibre cable core
US5153156A (en) 1989-04-18 1992-10-06 Aristech Chemical Corporation Process for making efficient anionic clay catalyst, catalysts made thereby, and method of making isophorone
FR2647433B1 (fr) * 1989-05-23 1991-10-31 Lafarge Coppee Da Procede de preparation par voie aqueuse de sulfate de calcium purifie
US4970079A (en) 1989-06-05 1990-11-13 Purdue Research Foundation Method and composition of oxy-iron compounds for treatment of hyperphosphatemia
US5112604A (en) 1989-09-01 1992-05-12 Riker Laboratories, Inc. Oral suspension formulation
ES2018952A6 (es) 1989-10-17 1991-05-16 Walton Sa Procedimiento de preparacion de composiciones antiacidas con tiempo prolongado de permanencia gastrica.
JP2918619B2 (ja) 1990-04-06 1999-07-12 花王株式会社 金属磁性粉末の製造方法及び磁気記録媒体用塗膜
JPH0414849A (ja) * 1990-05-09 1992-01-20 Shibayama Kikai Kk チャック機構における半導体ウエハの取外し方法
WO1991018835A1 (en) 1990-06-08 1991-12-12 Commonwealth Scientific And Industrial Research Organisation Ethylene sorbing substances
US5300302A (en) 1990-10-04 1994-04-05 Nestec S.A. Pharmaceutical composition in gel form in a dispensing package
DE4036757A1 (de) * 1990-11-17 1992-05-21 Bayer Ag Antazida-zubereitung mit verlaengerter magenverweilzeit
GB2253164B (en) * 1991-02-22 1994-10-05 Hoechst Uk Ltd Improvements in or relating to electrostatic coating of substrates of medicinal products
GB2254556B (en) 1991-04-11 1995-04-12 Fisons Plc Formulations containing linolenic acid
US5246899A (en) 1991-08-16 1993-09-21 Amoco Corporation Simplified preparation of hydrotalcite-type clays
JPH05155776A (ja) * 1991-12-02 1993-06-22 Otsuka Pharmaceut Factory Inc 高リン血症治療剤
JPH05208816A (ja) * 1992-01-28 1993-08-20 Sumitomo Metal Mining Co Ltd 水酸化セリウム及び酸化セリウムの製造方法
AU5155893A (en) 1992-04-30 1993-11-29 J.M. Huber Corporation Method for production of synthetic hydrotalcite
US5380542A (en) 1992-06-19 1995-01-10 Rhone-Poulenc Specialties Chemical Co. Dietary fiber compositions for use in foods
US5273767A (en) 1992-09-09 1993-12-28 Merck & Co., Inc. Rapidly hydrating gums
AU5589594A (en) 1992-10-29 1994-05-24 C-P Technology Limited Partnership Mixtures or complexes containing calcium and sulfate
NL9201907A (nl) 1992-11-02 1994-06-01 Tno Peristaltisch mengende reactor en peristaltische kleppenpomp.
DE4239442C2 (de) * 1992-11-24 2001-09-13 Sebo Gmbh Verwendung eines mit polynuklearen Metalloxidhydroxiden modifizierten Adsorptionsmaterials zur selektiven Elimination von anorganischem Phosphat aus proteinhaltigen Flüssigkeiten
CA2110313C (en) * 1992-12-01 2004-10-26 Edward John Roche Pharmaceutical compositions containing a guanidinothiazole compound and antacids
US5506248A (en) 1993-08-02 1996-04-09 Bristol-Myers Squibb Company Pharmaceutical compositions having good dissolution properties
TW397686B (en) * 1993-08-11 2000-07-11 Takeda Chemical Industries Ltd Antacid compositions and pharmaceutical compositions
WO1995011033A1 (en) 1993-10-22 1995-04-27 Commonwealth Scientific And Industrial Research Organisation Polyoxometallates in the treatment of flavivirus infections
TW390813B (en) 1994-04-29 2000-05-21 Merck & Co Inc Wet granulation formulation for bisphosphonic acids
SK281514B6 (sk) 1994-09-21 2001-04-09 Unilever N. V. Orálna zmes obsahujúca aglomeráty časticových materiálov
GB9506126D0 (en) * 1995-03-25 1995-05-10 Johnson Matthey Plc Pharmaceutical composition and method
MY128552A (en) 1995-09-20 2007-02-28 Univ Queensland Novel acc synthase genes
US5571336A (en) * 1995-09-29 1996-11-05 Wurzburger; Stephen R. Base solution for cleaning aluminum
DE19547356A1 (de) * 1995-12-19 1997-06-26 Vifor Int Ag Adsorbens für Phosphat aus wäßrigem Medium, dessen Herstellung und Verwendung
PL328148A1 (en) 1996-01-25 1999-01-18 Colin Leslie Young Mollescide exerting an effect onto stomach
SE9602442D0 (sv) 1996-06-20 1996-06-20 Astra Ab Administration of pharmaceuticals
CN1222317C (zh) * 1996-07-12 2005-10-12 第一制药株式会社 可迅速崩解的压模物质及其生产方法
US5654011A (en) 1996-07-30 1997-08-05 Energetics, Inc. Dietary supplements
JPH1059842A (ja) 1996-08-13 1998-03-03 Lion Corp 錠剤用組成物及び打錠方法
JPH10101569A (ja) 1996-10-01 1998-04-21 Eisai Co Ltd 制酸剤
JPH10236960A (ja) 1997-02-24 1998-09-08 Lion Corp 制酸剤含有組成物
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
JP3835638B2 (ja) 1997-06-13 2006-10-18 カルソニックカンセイ株式会社 自動車用空気調和装置
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
US6028023A (en) * 1997-10-20 2000-02-22 Bulldog Technologies U.S.A., Inc. Process for making, and use of, anionic clay materials
PT1058538E (pt) * 1998-03-06 2002-11-29 Eurand Int Comprimidos de desintegracao rapida
JPH11335269A (ja) * 1998-05-19 1999-12-07 Hisamitsu Pharmaceut Co Inc 遺伝子関連医薬の経口投与固形製剤
CN1330786A (zh) * 1998-07-10 2002-01-09 摩托罗拉公司 在无线通信系统中使用选择性呼叫接收器来提供人口统计信息,兑换优惠券,和模仿会员卡的方法和装置
US6171678B1 (en) * 1998-07-14 2001-01-09 Bayer Antwerp N.V. Polyurethane carpet backings with improved tuft bind
JP2000086537A (ja) 1998-09-11 2000-03-28 Fuji Chem Ind Co Ltd 無機化合物糖類組成物、賦形剤、速崩壊性圧縮成型物及びその製造方法
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
KR100331529B1 (ko) * 1999-06-16 2002-04-06 민경윤 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법
US6448323B1 (en) * 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
US6177581B1 (en) * 1999-10-12 2001-01-23 The Dow Chemical Company Mixed-metal chelates and process for the preparation thereof
US6733780B1 (en) * 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
DE19958007A1 (de) 1999-12-02 2001-06-07 Roehm Gmbh Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen
EP1246630A4 (en) 2000-01-06 2007-04-18 Marantech Holding Llc COMPOSITIONS AND METHODS FOR PROMOTING SKIN GROWTH AND TREATING SKIN STATE
AUPQ533700A0 (en) 2000-01-28 2000-02-17 Commonwealth Scientific And Industrial Research Organisation Soil treatment method
FR2809407B1 (fr) 2000-05-26 2002-08-30 Rhodia Chimie Sa Utilisation d'hydrotalcite comme charge dans des compositions de polymeres
US20030185886A1 (en) * 2000-05-26 2003-10-02 Hanmi Pharm. Co., Ltd. Process for the preparation of rapidly disintegrating tablet
US6720005B1 (en) 2000-07-07 2004-04-13 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Coated, platform-generating tablet
IN192168B (el) 2000-11-24 2004-03-06 Council Scient Ind Res
CA2342007C (en) * 2001-03-26 2009-10-20 University Technologies International, Inc. Determination of oil and water compositions of oil/water emulsions using low field nmr relaxometry
US6576665B2 (en) * 2001-04-03 2003-06-10 Braintree Laboratories, Inc. Encapsulated calcium acetate caplet and a method for inhibiting gastrointestinal phosphorous absorption
WO2003003809A2 (en) 2001-07-05 2003-01-16 Marantech Holding, Llc Methods of using electron active compounds for managing conditions afflicting mammals
UA80682C2 (en) 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
RU2284189C2 (ru) * 2001-08-27 2006-09-27 Киова Кемикал Индастри Ко., Лтд. Антацидная и слабительная таблетка
AR036354A1 (es) 2001-08-31 2004-09-01 Takeda Chemical Industries Ltd Preparacion solida
CN1284532C (zh) 2001-09-28 2006-11-15 株式会社三和化学研究所 有核型速溶崩解性成型品
GB0204771D0 (en) 2002-02-28 2002-04-17 Phoqus Ltd Fast disintegrating tablets
US7300670B2 (en) 2002-04-03 2007-11-27 Unilab Pharmatech, Ltd. Oral suspension formulation
ATE329582T1 (de) 2002-04-29 2006-07-15 Egyt Gyogyszervegyeszeti Gyar Herstellung von tabletten von pharmazeutisch aktiven substanzen mit ungünstigen tablettierungseigenschaften mit einer mikrokristalline zellulose enthaltenden granulierflüssigkeit
US20040161474A1 (en) 2002-05-24 2004-08-19 Moerck Rudi E. Rare earth metal compounds methods of making, and methods of using the same
EP1551882B1 (en) 2002-06-25 2016-05-11 Solvay USA Inc. Molecular weight reduction of polysaccharides by electron beams
CN1326612C (zh) 2002-08-09 2007-07-18 阿尔伯麦尔荷兰有限公司 使用含铁层状材料的费－托法
JP4348426B2 (ja) 2002-08-29 2009-10-21 独立行政法人産業技術総合研究所 高選択性脱リン剤及びその製造方法
CA2513469C (en) 2003-01-28 2016-05-17 The University Of Wyoming Research Corporation D/B/A/ Western Research Institute Bioagent air filtration systems
AR045068A1 (es) 2003-07-23 2005-10-12 Univ Missouri Formulacion de liberacion inmediata de composiciones farmaceuticas
US7381428B2 (en) 2003-08-26 2008-06-03 Shire International Licensing B.V. Stabilized lanthanum carbonate compositions
HUE024906T2 (en) 2003-08-26 2016-02-29 Shire Biopharmaceuticals Holdings Ireland Ltd Pharmaceutical composition containing lanthanum compounds
EP1696889A1 (en) 2003-08-28 2006-09-06 Ranbaxy Laboratories, Ltd. Pharmaceutical compositions of benzimidazole and processes for their preparation
US20050260271A1 (en) * 2004-05-20 2005-11-24 Eastman Kodak Company Composition comprising layered host material with intercalated functional-active organic compound
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20060177415A1 (en) 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
GB0502787D0 (en) * 2005-02-10 2005-03-16 Ineos Silicas Ltd Pharmaceuticlly active compounds, their manufacture, compositions containing them and their use
JP4823547B2 (ja) 2005-03-28 2011-11-24 株式会社ジーシー ペースト状歯科用アルギン酸塩印象材組成物
SG184754A1 (en) 2005-12-28 2012-10-30 Takeda Pharmaceutical Controlled release solid preparation
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
EP2034958B1 (en) 2006-05-19 2009-10-28 Norbrook Laboratories Limited Stable aqueous suspension having palatable taste
ES2526171T3 (es) 2006-12-14 2015-01-07 Novartis Ag Adsorbente de fosfato a base de hierro (III)-carbohidratos
PL2319804T3 (pl) 2006-12-14 2015-03-31 Elanco Tiergesundheit Ag Węglowodanowy adsorbent fosforanów oparty na żelazie (III)
EP1946750A1 (en) 2007-01-18 2008-07-23 The Jordanian Pharmaceutical Manufacturing Co. Co-precipitate, method for preparing the same and uses thereof
WO2008129034A1 (en) 2007-04-20 2008-10-30 Euro Support Catalyst Group Bv Hydrotalcite-like layered double hydroxide (ldh) composition and process of making same
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition

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