CY1105501T1 - Συνδυασμοι φαρμακων (π.χ. chlorpromazine και pentamidine) για την αντιμετωπιση νεοπλαστικων διαταραχων - Google Patents

Συνδυασμοι φαρμακων (π.χ. chlorpromazine και pentamidine) για την αντιμετωπιση νεοπλαστικων διαταραχων

Info

Publication number
CY1105501T1
CY1105501T1 CY20061100653T CY061100653T CY1105501T1 CY 1105501 T1 CY1105501 T1 CY 1105501T1 CY 20061100653 T CY20061100653 T CY 20061100653T CY 061100653 T CY061100653 T CY 061100653T CY 1105501 T1 CY1105501 T1 CY 1105501T1
Authority
CY
Cyprus
Prior art keywords
pentamidine
chlorpromazine
treatment
drug combinations
neoplastic disorders
Prior art date
Application number
CY20061100653T
Other languages
English (en)
Inventor
Alexis Borisy
Curtis Keith
Michael A. Foley
Brent R. Stockwell
Original Assignee
Combinatorx, Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Combinatorx, Incorporated filed Critical Combinatorx, Incorporated
Publication of CY1105501T1 publication Critical patent/CY1105501T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Η εφεύρεση αναφέρεται σε μία μέθοδο για τη θεραπευτική αγωγή σ' έναν ασθενή που πάσχει από καρκίνο ή άλλο νεόπλασμα, με χορήγηση στον ασθενή (i) chlorpromazine ή έναν μεταβολίτη ή ανάλογο αυτού· και (ii) pentamidine ή έναν μεταβολίτη ή ανάλογο αυτού ταυτόχρονα ή μέσα σε 14 ημέρες το ένα από το άλλο σε ποσότητες που επαρκούν για την αναστολή της ανάπτυξης του νεοπλάσματος.
CY20061100653T 2000-11-06 2006-05-19 Συνδυασμοι φαρμακων (π.χ. chlorpromazine και pentamidine) για την αντιμετωπιση νεοπλαστικων διαταραχων CY1105501T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/706,929 US6569853B1 (en) 2000-11-06 2000-11-06 Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders
PCT/US2001/047959 WO2002058684A2 (en) 2000-11-06 2001-10-30 Combinations of drugs (e.g., chlorpromazine and pentamidine) for the treatment of neoplastic disorders

Publications (1)

Publication Number Publication Date
CY1105501T1 true CY1105501T1 (el) 2010-04-28

Family

ID=24839666

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100653T CY1105501T1 (el) 2000-11-06 2006-05-19 Συνδυασμοι φαρμακων (π.χ. chlorpromazine και pentamidine) για την αντιμετωπιση νεοπλαστικων διαταραχων

Country Status (29)

Country Link
US (4) US6569853B1 (el)
EP (1) EP1339399B1 (el)
JP (1) JP2004517915A (el)
KR (1) KR100720205B1 (el)
CN (1) CN1484525A (el)
AR (1) AR035500A1 (el)
AT (1) ATE318590T1 (el)
AU (1) AU2002246636B8 (el)
BG (1) BG107831A (el)
BR (1) BR0115166A (el)
CA (1) CA2436799C (el)
CY (1) CY1105501T1 (el)
DE (1) DE60117615T2 (el)
DK (1) DK1339399T3 (el)
EE (1) EE200300212A (el)
ES (1) ES2258566T3 (el)
HR (1) HRP20030460A2 (el)
HU (1) HUP0400529A3 (el)
IL (1) IL155795A0 (el)
IS (1) IS2457B (el)
MX (1) MXPA03003960A (el)
NO (1) NO20032036L (el)
NZ (1) NZ525773A (el)
PL (1) PL362690A1 (el)
PT (1) PT1339399E (el)
RU (1) RU2286769C2 (el)
SK (1) SK5452003A3 (el)
TW (1) TWI259077B (el)
WO (1) WO2002058684A2 (el)

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US20050158320A1 (en) * 2003-11-12 2005-07-21 Nichols M. J. Combinations for the treatment of proliferative diseases
US20050100508A1 (en) * 2003-11-12 2005-05-12 Nichols M. J. Methods for identifying drug combinations for the treatment of proliferative diseases

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DE60117615T2 (de) 2006-11-09
CA2436799C (en) 2007-12-18
HUP0400529A2 (hu) 2004-06-28
SK5452003A3 (en) 2004-07-07
WO2002058684A3 (en) 2003-04-17
IS2457B (is) 2008-11-15
NO20032036D0 (no) 2003-05-06
KR20030048460A (ko) 2003-06-19
WO2002058684A2 (en) 2002-08-01
CA2436799A1 (en) 2002-08-01
BR0115166A (pt) 2003-12-30
BG107831A (bg) 2004-02-27
EP1339399B1 (en) 2006-03-01
US20050192274A1 (en) 2005-09-01
TWI259077B (en) 2006-08-01
US6846816B2 (en) 2005-01-25
HUP0400529A3 (en) 2006-02-28
AU2002246636B8 (en) 2006-01-19
JP2004517915A (ja) 2004-06-17
ES2258566T3 (es) 2006-09-01
KR100720205B1 (ko) 2007-05-21
AU2002246636B2 (en) 2005-12-01
PT1339399E (pt) 2006-07-31
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US6569853B1 (en) 2003-05-27
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