ATE532517T1 - Thioridazin und seine derivate zur umkehr von antimikrobieller arzneimittelresistenz - Google Patents
Thioridazin und seine derivate zur umkehr von antimikrobieller arzneimittelresistenzInfo
- Publication number
- ATE532517T1 ATE532517T1 AT04798860T AT04798860T ATE532517T1 AT E532517 T1 ATE532517 T1 AT E532517T1 AT 04798860 T AT04798860 T AT 04798860T AT 04798860 T AT04798860 T AT 04798860T AT E532517 T1 ATE532517 T1 AT E532517T1
- Authority
- AT
- Austria
- Prior art keywords
- thioridazine
- antibacterials
- derivatives
- reverting
- drug resistance
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200301690 | 2003-11-13 | ||
PCT/IB2004/003730 WO2005046694A1 (en) | 2003-11-13 | 2004-11-15 | Thioridazine and derivatives thereof for reversing anti-microbial drug-resistance |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE532517T1 true ATE532517T1 (de) | 2011-11-15 |
Family
ID=34585771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04798860T ATE532517T1 (de) | 2003-11-13 | 2004-11-15 | Thioridazin und seine derivate zur umkehr von antimikrobieller arzneimittelresistenz |
Country Status (6)
Country | Link |
---|---|
US (1) | US8623864B2 (de) |
EP (1) | EP1689405B1 (de) |
AT (1) | ATE532517T1 (de) |
DK (1) | DK1689405T3 (de) |
ES (1) | ES2377016T3 (de) |
WO (1) | WO2005046694A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1689405B1 (de) | 2003-11-13 | 2011-11-09 | Noa Sic Aps | Thioridazin und seine derivate zur umkehr von antimikrobieller arzneimittelresistenz |
DK1744781T3 (da) * | 2004-04-30 | 2012-10-15 | Bkg Pharma Aps | Behandling af infektionssygdomme |
EP2246349A1 (de) * | 2009-04-20 | 2010-11-03 | BKG Pharma ApS | Behandlung von Infektionskrankheiten |
US20160120876A1 (en) * | 2014-04-28 | 2016-05-05 | Chi-Ying Huang | Pharmaceutical composition for treatment of cancer using phenothiazine |
US9198916B1 (en) | 2014-05-27 | 2015-12-01 | B&G Partners, Llc | Compounds and methods for treating tumors |
WO2017212239A1 (en) * | 2016-06-07 | 2017-12-14 | Novabiotics Limited | Treatment of drug-resistant microbial infections |
WO2018070874A1 (en) * | 2016-10-12 | 2018-04-19 | Rijksuniversiteit Groningen | Means and methods for reducing or avoiding antibiotic resistance and spread of virulence in human pathogens |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL105360C (de) | 1957-07-31 | |||
FR2813792B1 (fr) | 2000-09-12 | 2003-03-14 | Inst Necker | Moyens pour la regulation des defenses immunitaires |
US6569853B1 (en) | 2000-11-06 | 2003-05-27 | Combinatorx, Incorporated | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
EP1360180A1 (de) | 2001-01-19 | 2003-11-12 | Cytokinetics, Inc. | Phenothiazinkinesininhibitoren |
WO2002089810A1 (en) | 2001-05-07 | 2002-11-14 | United States Army Medical Research And Materiel Command | Chemosensitizing agents against chloroquine resistant plasmodium falciparum and methods of making and using thereof |
US20030229082A1 (en) | 2002-01-16 | 2003-12-11 | The Regents Of The University Of California | Inhibition of RNA function |
EP1689405B1 (de) | 2003-11-13 | 2011-11-09 | Noa Sic Aps | Thioridazin und seine derivate zur umkehr von antimikrobieller arzneimittelresistenz |
-
2004
- 2004-11-15 EP EP04798860A patent/EP1689405B1/de not_active Not-in-force
- 2004-11-15 ES ES04798860T patent/ES2377016T3/es active Active
- 2004-11-15 DK DK04798860.5T patent/DK1689405T3/da active
- 2004-11-15 US US10/579,112 patent/US8623864B2/en not_active Expired - Fee Related
- 2004-11-15 WO PCT/IB2004/003730 patent/WO2005046694A1/en active Application Filing
- 2004-11-15 AT AT04798860T patent/ATE532517T1/de active
Also Published As
Publication number | Publication date |
---|---|
US20070287702A1 (en) | 2007-12-13 |
DK1689405T3 (da) | 2012-02-20 |
EP1689405A1 (de) | 2006-08-16 |
WO2005046694A1 (en) | 2005-05-26 |
EP1689405B1 (de) | 2011-11-09 |
US8623864B2 (en) | 2014-01-07 |
ES2377016T3 (es) | 2012-03-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200800798A1 (ru) | Фармацевтические композиции, предназначенные для лечения нарушений внутреннего уха | |
DE60004374D1 (de) | Zusammensetzung zur behandlung von infektionen bei mensch und tier | |
CL2004000234A1 (es) | Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid | |
ATE410424T1 (de) | Spirocyclische cyclohexan-derivate | |
BR112014031279A2 (pt) | composições sinérgicas para a proteção de culturas agrícolas e o uso das mesmas | |
MX2015012760A (es) | Composicion farmaceutica que comprende un activador de ampk y un agente serotonergico y metodos de uso de la misma. | |
DE60331537D1 (de) | Kombinationen zur behandlung von multiplem myelom | |
MY140826A (en) | Substituted pyrazoline compounds, their preparation and use as medicaments. | |
WO2005014533A3 (en) | Aryl and heteroaryl compounds, compositions, and methods of use | |
EA200901032A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
BRPI0418099A (pt) | compostos, composição farmacêutica, e uso de um composto | |
EA201070169A1 (ru) | 2,3-дигидробензо[1,4]диоксин-2-илметиловые производные в качестве альфа2с антагонистов для применения в лечении заболеваний перифирической центральной нервной системы | |
BRPI0511527A (pt) | compostos e composições como moduladores de ppar | |
EA200601846A1 (ru) | Содержащие бензоксазины лекарственные комбинации для лечения заболеваний дыхательных путей | |
ATE456369T1 (de) | Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen | |
CY1108196T1 (el) | Αντιμικροβιακες φαρμακευτικες συνθεσεις χορηγουμενες απο το στομα | |
EP4272832A3 (de) | Antimikrobielle verbindungen, zusammensetzungen sowie verwendungen davon | |
DE602005010744D1 (de) | Piperazinylpyridinderivate als mittel gegen adipositas | |
EA201690021A1 (ru) | Алкалоидные композиции из вида ribes для лечения состояний, связанных с функцией митохондрий или ингибированием pde4, pde5 и ikk-бета | |
ATE541567T1 (de) | Pharmazeutische zusammensetzung zur prävention und behandlung von metabolischen knochenerkrankungen mit alpha-arylmethoxyacrylat- derivaten | |
DE602007014206D1 (de) | Neuartige serotonin-wiederaufnahmehemmer als arzneimittel mit peripheriesystem-beschränkter aktivität | |
ATE522500T1 (de) | Amidderivate als ionenkanalliganden sowie pharmazeutische zusammensetzungen und verwendungsverfahren dafür | |
ATE532517T1 (de) | Thioridazin und seine derivate zur umkehr von antimikrobieller arzneimittelresistenz | |
ATE509018T1 (de) | Als antimikrobielle mittel geeignete bisindolpyrrole | |
EA200900269A1 (ru) | Лекарственные комбинации для лечения заболеваний дыхательных путей |