DK1339399T3 - Kombinationer af medikamenter (fx. chlorpromazin og pentamidin) til behandling af neoplastiske lidelser - Google Patents
Kombinationer af medikamenter (fx. chlorpromazin og pentamidin) til behandling af neoplastiske lidelserInfo
- Publication number
- DK1339399T3 DK1339399T3 DK01994213T DK01994213T DK1339399T3 DK 1339399 T3 DK1339399 T3 DK 1339399T3 DK 01994213 T DK01994213 T DK 01994213T DK 01994213 T DK01994213 T DK 01994213T DK 1339399 T3 DK1339399 T3 DK 1339399T3
- Authority
- DK
- Denmark
- Prior art keywords
- pentamidine
- chlorpromazine
- medications
- combinations
- neoplastic disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/706,929 US6569853B1 (en) | 2000-11-06 | 2000-11-06 | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1339399T3 true DK1339399T3 (da) | 2006-06-19 |
Family
ID=24839666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01994213T DK1339399T3 (da) | 2000-11-06 | 2001-10-30 | Kombinationer af medikamenter (fx. chlorpromazin og pentamidin) til behandling af neoplastiske lidelser |
Country Status (29)
Country | Link |
---|---|
US (4) | US6569853B1 (da) |
EP (1) | EP1339399B1 (da) |
JP (1) | JP2004517915A (da) |
KR (1) | KR100720205B1 (da) |
CN (1) | CN1484525A (da) |
AR (1) | AR035500A1 (da) |
AT (1) | ATE318590T1 (da) |
AU (1) | AU2002246636B8 (da) |
BG (1) | BG107831A (da) |
BR (1) | BR0115166A (da) |
CA (1) | CA2436799C (da) |
CY (1) | CY1105501T1 (da) |
DE (1) | DE60117615T2 (da) |
DK (1) | DK1339399T3 (da) |
EE (1) | EE200300212A (da) |
ES (1) | ES2258566T3 (da) |
HR (1) | HRP20030460A2 (da) |
HU (1) | HUP0400529A3 (da) |
IL (1) | IL155795A0 (da) |
IS (1) | IS2457B (da) |
MX (1) | MXPA03003960A (da) |
NO (1) | NO20032036L (da) |
NZ (1) | NZ525773A (da) |
PL (1) | PL362690A1 (da) |
PT (1) | PT1339399E (da) |
RU (1) | RU2286769C2 (da) |
SK (1) | SK5452003A3 (da) |
TW (1) | TWI259077B (da) |
WO (1) | WO2002058684A2 (da) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU780538B2 (en) * | 1999-11-16 | 2005-03-24 | Oncozyme Pharma Inc. | Inhibitors of endo-exonuclease activity for treating cancer |
DE10015818A1 (de) * | 2000-03-30 | 2001-10-18 | Infineon Technologies Ag | Biosensor und Verfahren zum Ermitteln makromolekularer Biopolymere mit einem Biosensor |
US6569853B1 (en) * | 2000-11-06 | 2003-05-27 | Combinatorx, Incorporated | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
US20030049320A1 (en) * | 2000-12-18 | 2003-03-13 | Wockhardt Limited | Novel in-situ forming controlled release microcarrier delivery system |
EP1360180A1 (en) * | 2001-01-19 | 2003-11-12 | Cytokinetics, Inc. | Phenothiazine kinesin inhibitors |
US6693125B2 (en) * | 2001-01-24 | 2004-02-17 | Combinatorx Incorporated | Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders |
WO2002069949A2 (en) * | 2001-03-06 | 2002-09-12 | Prendergast Patrick T | Combination therapy for reduction of toxycity of chemotherapeutic agents |
ATE401880T1 (de) * | 2001-05-31 | 2008-08-15 | Cleveland Clinic Foundation | Ptpase-inhibitoren und verfahren zu ihrer verwendung |
FR2825279B1 (fr) * | 2001-06-01 | 2005-04-08 | Molecular Engines Lab | Medicament utile dans le traitement du cancer |
US20040010045A1 (en) * | 2001-09-07 | 2004-01-15 | Taolin Yi | Therapeutic compositions comprised of pentamidine and methods of using same to treat cancer |
EP1572070A4 (en) * | 2001-09-07 | 2009-11-04 | Cleveland Clinic Foundation | THERAPEUTIC COMPOSITIONS AND METHOD FOR MODULATING PROTEIN TYROSINE PHOSPHATASES |
US20050215629A1 (en) * | 2001-09-07 | 2005-09-29 | Taolin Yi | PTPase inhibitors and methods of using the same |
US7544681B2 (en) * | 2001-09-27 | 2009-06-09 | Ramot At Tel Aviv University Ltd. | Conjugated psychotropic drugs and uses thereof |
AU2004201240B2 (en) * | 2001-09-27 | 2008-08-07 | Bar Ilan University | Conjugated Psychotropic Drugs and Uses Thereof |
US8053477B2 (en) * | 2002-03-29 | 2011-11-08 | University Of Maryland, Baltimore | Inhibitors of the S100-p53 protein-protein interaction and method of inhibiting cancer employing the same |
AU2003241346A1 (en) * | 2002-05-01 | 2003-11-17 | The Cleveland Clinic Foundation | Therapeutic compositions comprised of pentamidine and methods of using same to treat cancer |
MXPA05000485A (es) * | 2002-07-11 | 2005-04-19 | Combinatorx Inc | Combinacion de farmacos para el tratamiento de neoplasmas. |
EP1606759B1 (en) * | 2003-03-26 | 2010-05-05 | Synergy Biosystems Ltd. | Methods to identify biologically active agents and synergistic combinations |
WO2004111199A2 (en) * | 2003-06-12 | 2004-12-23 | University Of Colorado System Technology | Systems and methods for treating human inflammatory and proliferative diseases and wounds, with fatty acid metabolism inhibitors and/or glycolytic inhibitors |
US20050054708A1 (en) * | 2003-07-28 | 2005-03-10 | Nichols Matthew James | Combinations of drugs for the treatment of neoplasms |
AR047938A1 (es) * | 2003-08-25 | 2006-03-15 | Combinatorx Inc | Formulaciones, conjugados y combinaciones de farmacos para el tratamiento de neoplasmas |
AU2004273910A1 (en) * | 2003-09-18 | 2005-03-31 | Combinatorx, Incorporated | Combinations of drugs for the treatment of neoplasms |
TW200526777A (en) * | 2003-11-12 | 2005-08-16 | Combinatorx Inc | Combinations for the treatment of proliferative diseases |
US20050158320A1 (en) * | 2003-11-12 | 2005-07-21 | Nichols M. J. | Combinations for the treatment of proliferative diseases |
US20050100508A1 (en) * | 2003-11-12 | 2005-05-12 | Nichols M. J. | Methods for identifying drug combinations for the treatment of proliferative diseases |
ATE532517T1 (de) * | 2003-11-13 | 2011-11-15 | Noa Sic Aps | Thioridazin und seine derivate zur umkehr von antimikrobieller arzneimittelresistenz |
US7510710B2 (en) * | 2004-01-08 | 2009-03-31 | The Regents Of The University Of Colorado | Compositions of UCP inhibitors, Fas antibody, a fatty acid metabolism inhibitor and/or a glucose metabolism inhibitor |
US20100009928A1 (en) * | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and taxanes and methods of use thereof |
US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
US20100173864A1 (en) | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
US20110008327A1 (en) | 2004-03-29 | 2011-01-13 | Cheng Jin Q | Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof |
PL2574341T3 (pl) | 2004-03-29 | 2017-09-29 | University Of South Florida | Efektywne leczenie guzów i raka fosforanem tricyrybiny |
CN1976723B (zh) | 2004-04-30 | 2010-12-29 | Bkg制药有限公司 | 制备治疗或预防感染性疾病的药物的用途 |
WO2005117847A2 (en) * | 2004-06-02 | 2005-12-15 | Combinatorx, Incorporated | Methods and compounds for the treatment of neoplasms |
EP1856247B1 (en) * | 2005-01-19 | 2016-05-04 | The Trustees of The University of Pennsylvania | Regulation of autophagy and cell survival |
TW200719903A (en) * | 2005-04-19 | 2007-06-01 | Combinatorx Inc | Compositions for the treatment of neoplasms |
JP2008539238A (ja) * | 2005-04-28 | 2008-11-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド | 治療用二機能性化合物 |
WO2006118821A2 (en) * | 2005-05-02 | 2006-11-09 | The Regents Of The University Of Colorado | Systems and methods for treating human inflammatory and proliferative diseases, with a combination of compounds, or a bifunctional compound,that provides fatty acid metabolism and glycolysis inhibition |
EP1896007B1 (en) | 2005-05-04 | 2014-03-19 | Medigene AG | Method of administering a cationic liposomal preparation comprising paclitexel |
DE102005024017A1 (de) * | 2005-05-25 | 2006-11-30 | Merck Patent Gmbh | Chinazolinone |
ES2400772T3 (es) * | 2005-06-07 | 2013-04-12 | Ramot At Tel Aviv University Ltd. | Sales novedosas de fármacos psicotrópicos conjugados y procedimientos para la preparación de las mismas |
CN1870631B (zh) * | 2005-11-11 | 2010-04-14 | 华为技术有限公司 | 媒体网关的门控方法 |
US20070202079A1 (en) * | 2006-01-11 | 2007-08-30 | Taolin Yi | Therapeutic compositions and methods useful in modulating protein tyrosine phosphatases |
MX2008011978A (es) | 2006-03-22 | 2009-04-22 | Medigene Ag | Tratamiento del cancer de seno negativo al triple receptor. |
WO2007149381A2 (en) * | 2006-06-19 | 2007-12-27 | The Cleveland Clinic Foundation | Compositions comprising a ptp-ase inhibitor and use thereof in treating cancer |
US20080226596A1 (en) * | 2006-06-19 | 2008-09-18 | Taolin Yi | Therapeutic compositions and methods useful in treating hepatitis |
KR20090048462A (ko) * | 2006-07-17 | 2009-05-13 | 라모트 앳 텔-아비브 유니버시티 리미티드 | 통증완화용 gaba 접합체 |
MX2009007235A (es) | 2007-01-05 | 2009-10-16 | Bkg Pharma Aps | "derivados de tioxanteno utiles para el tratamiento de enfermedades infecciosas.". |
JP5201743B2 (ja) * | 2007-01-09 | 2013-06-05 | フォヴェア ファルマシューティカル | 眼内注射装置 |
DE102007013855A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Substituierte Tetrahydrochinoline |
DE102007013856A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Substituierte Tetrahydropyrrolochinoline |
DE102007013854A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Tetrahydrochinoline |
CA2687715A1 (en) * | 2007-05-09 | 2008-11-20 | Traffick Therapeutics Inc. | Screening assay to identify correctors of protein trafficking defects |
CN101138558B (zh) * | 2007-09-13 | 2010-08-25 | 汕头大学医学院 | 喷他脒及死亡结构域受体配体联合应用 |
EP2194981B1 (en) * | 2007-10-05 | 2011-11-23 | Université de Mons-Hainaut | Bisbenzimidazoles as antimalarial agents |
EP2252578B1 (en) | 2008-02-11 | 2012-08-01 | Ramot at Tel Aviv University Ltd. | Conjugates for treating neurodegenerative diseases and disorders |
WO2009148623A2 (en) * | 2008-06-05 | 2009-12-10 | Stc.Unm | Methods and related compositions for the treatment of cancer |
EP2318008A1 (en) * | 2008-07-18 | 2011-05-11 | Immune Control, Inc. | Binding and inhibiting 5-ht4 receptor |
US8993625B2 (en) | 2009-03-11 | 2015-03-31 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle |
US9034389B2 (en) | 2009-03-11 | 2015-05-19 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
CN102573826A (zh) * | 2009-05-01 | 2012-07-11 | 奥克兹美制药公司 | 用于治疗癌症的喷他脒组合 |
WO2010134039A2 (en) | 2009-05-20 | 2010-11-25 | Universite De Geneve | Mitochondrial activity inhibitors of cancer-initiating cells and use thereof |
US20120277193A1 (en) * | 2009-09-21 | 2012-11-01 | President And Fellows Of Harvard College | Synergistic Combination Therapy |
EP2509603A1 (en) * | 2009-12-09 | 2012-10-17 | Biolinerx Ltd. | Methods of improving cognitive functions |
US20130165417A1 (en) * | 2010-04-23 | 2013-06-27 | University Of Florida Research Foundation | Methods and compositions for treating ace2-related disorders |
US8916610B2 (en) | 2010-09-22 | 2014-12-23 | Ramot At Tel-Aviv University Ltd. | Acid addition salt of a nortriptyline-GABA conjugate and a process of preparing same |
RS55557B1 (sr) * | 2011-07-25 | 2017-05-31 | Dritte Patentportfolio Beteili | Amidoksimski estri karboksilnih kiselina pentamidina kao prolekovi i njihova primena kao lekova |
CA2843338C (en) | 2011-08-02 | 2020-08-25 | Helmholtz Zentrum Munchen - Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) | Selective inhibition of malt1 protease by phenothiazine derivatives |
WO2014086478A1 (en) * | 2012-12-03 | 2014-06-12 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Inhibitors of malt1 protease |
MX2015007945A (es) * | 2012-12-21 | 2016-02-16 | Verlyx Pharma Inc | Usos y métodos para el tratamiento de enfermedades o afecciones hepáticas. |
RU2530651C1 (ru) * | 2013-11-06 | 2014-10-10 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт фармакологии" Сибирского отделения Российской академии медицинских наук | Средство, обладающее противовоспалительным и антифибротическим действием в легочной ткани при цитостатическом воздействии |
KR101538264B1 (ko) * | 2014-01-24 | 2015-07-20 | 계명대학교 산학협력단 | 티오리다진과 트레일을 유효성분으로 함유하는 암 예방 또는 치료용 약학조성물 |
CN105125571B (zh) * | 2015-07-17 | 2018-11-06 | 四川大学 | Prmt1抑制剂在制备治疗可卡因成瘾的药物中的用途 |
US20210378992A1 (en) * | 2018-10-19 | 2021-12-09 | Auransa Inc. | Methods for treating a subtype of small cell lung cancer |
CN109793727A (zh) * | 2019-03-13 | 2019-05-24 | 湖北科技学院 | 一种有效抗恶性肿瘤的药物组合物及其应用 |
KR102562739B1 (ko) * | 2020-09-11 | 2023-08-03 | 연세대학교 산학협력단 | 암의 기원 세포의 사멸용 약학적 조성물 |
KR102315103B1 (ko) * | 2021-01-21 | 2021-10-20 | 주식회사 뉴캔서큐어바이오 | 티오리다진 및 퍼헥실린을 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2645640A (en) * | 1953-07-14 | Phenthiazine derivatives | ||
GB1288376A (da) | 1968-10-29 | 1972-09-06 | ||
DE3827974A1 (de) * | 1988-08-18 | 1990-02-22 | Boehringer Mannheim Gmbh | Kombinationspraeparate von proteinkinase-c-inhibitoren mit lipiden, lipid-analoga, cytostatica oder inhibitoren von phospholipasen |
US5104858A (en) | 1988-09-29 | 1992-04-14 | Yale University | Sensitizing multidrug resistant cells to antitumor agents |
CH681780A5 (en) * | 1991-02-25 | 1993-05-28 | Patrinove | Anticancer compsns. - consists of a cytotoxic agent with a agent to prevent multi:drug resistance, e.g. in liposome(s) |
US5428051A (en) * | 1992-10-13 | 1995-06-27 | University Of North Carolina | Methods of combating pneumocystis carinii pneumonia and compounds useful therefor |
US5443962A (en) * | 1993-06-04 | 1995-08-22 | Mitotix, Inc. | Methods of identifying inhibitors of cdc25 phosphatase |
US5602172A (en) * | 1994-05-06 | 1997-02-11 | The University Of North Carolina At Chapel Hill | Methods of inhibiting Pneumocystis carinii pneumonia, Giardia lamblia, and Cryptosporidium and compounds useful therefor |
US5521189A (en) * | 1994-05-06 | 1996-05-28 | The University Of Nc At Ch | Methods of treating pneumocystis carinii pneumonia |
US5770585A (en) | 1995-05-08 | 1998-06-23 | Kaufman; Robert J. | Homogeneous water-in-perfluorochemical stable liquid dispersion for administration of a drug to the lung of an animal |
US5643935A (en) * | 1995-06-07 | 1997-07-01 | The University Of North Carolina At Chapel Hill | Method of combatting infectious diseases using dicationic bis-benzimidazoles |
US5723495A (en) * | 1995-11-16 | 1998-03-03 | The University Of North Carolina At Chapel Hill | Benzamidoxime prodrugs as antipneumocystic agents |
US6280768B1 (en) * | 1996-07-03 | 2001-08-28 | Prm Pharmaceuticals, Inc. | Berberine alkaloids as a treatment for chronic protozoally induced diarrhea |
US6008247A (en) * | 1998-02-27 | 1999-12-28 | The University Of North Carolina At Chapel Hill | 2,4-bis[(4-amidino)phenyl]furans as anti-Pneumocystis carinii agents |
HUP0102612A2 (hu) | 1998-03-12 | 2001-11-28 | Novo Nordisk A/S | Fehérje-tirozinfoszfatázokat moduláló vegyületek és ezeket tartalmazó gyógyászati készítmények |
JP2003523927A (ja) * | 1998-08-20 | 2003-08-12 | ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | ジカチオンジベンゾフランおよびジベンゾチオフェン化合物並びにその使用法 |
AU770656B2 (en) * | 1998-09-17 | 2004-02-26 | Duke University | Antifungal activity of dicationic molecules |
JP3679943B2 (ja) * | 1999-03-02 | 2005-08-03 | 大日本印刷株式会社 | パターン形成体の製造方法 |
AU780538B2 (en) | 1999-11-16 | 2005-03-24 | Oncozyme Pharma Inc. | Inhibitors of endo-exonuclease activity for treating cancer |
US6777433B2 (en) * | 1999-12-22 | 2004-08-17 | Merck Frosst Canada & Co. | Protein tyrosine phosphatase 1B (PTP-1B) inhibitors containing two ortho-substituted aromatic phosphonates |
CA2410338A1 (en) * | 2000-05-22 | 2001-11-29 | Takeda Chemical Industries, Ltd. | Tyrosine phosphatase inhibitors |
US6569853B1 (en) * | 2000-11-06 | 2003-05-27 | Combinatorx, Incorporated | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
US6642221B1 (en) * | 2000-11-15 | 2003-11-04 | Parker Hughes Institute | Vanadium compounds as anti-proliferative agents |
US6693125B2 (en) * | 2001-01-24 | 2004-02-17 | Combinatorx Incorporated | Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders |
US20030161893A1 (en) * | 2001-09-07 | 2003-08-28 | Taolin Yi | PTPase inhibitors and methods of using the same |
MXPA05000485A (es) * | 2002-07-11 | 2005-04-19 | Combinatorx Inc | Combinacion de farmacos para el tratamiento de neoplasmas. |
US20050054708A1 (en) * | 2003-07-28 | 2005-03-10 | Nichols Matthew James | Combinations of drugs for the treatment of neoplasms |
AR047938A1 (es) * | 2003-08-25 | 2006-03-15 | Combinatorx Inc | Formulaciones, conjugados y combinaciones de farmacos para el tratamiento de neoplasmas |
AU2004273910A1 (en) * | 2003-09-18 | 2005-03-31 | Combinatorx, Incorporated | Combinations of drugs for the treatment of neoplasms |
US20050100508A1 (en) * | 2003-11-12 | 2005-05-12 | Nichols M. J. | Methods for identifying drug combinations for the treatment of proliferative diseases |
US20050158320A1 (en) * | 2003-11-12 | 2005-07-21 | Nichols M. J. | Combinations for the treatment of proliferative diseases |
-
2000
- 2000-11-06 US US09/706,929 patent/US6569853B1/en not_active Expired - Fee Related
-
2001
- 2001-10-30 AU AU2002246636A patent/AU2002246636B8/en not_active Ceased
- 2001-10-30 EP EP01994213A patent/EP1339399B1/en not_active Expired - Lifetime
- 2001-10-30 JP JP2002559018A patent/JP2004517915A/ja active Pending
- 2001-10-30 CN CNA018217230A patent/CN1484525A/zh active Pending
- 2001-10-30 SK SK545-2003A patent/SK5452003A3/sk not_active Application Discontinuation
- 2001-10-30 ES ES01994213T patent/ES2258566T3/es not_active Expired - Lifetime
- 2001-10-30 WO PCT/US2001/047959 patent/WO2002058684A2/en active IP Right Grant
- 2001-10-30 BR BR0115166-5A patent/BR0115166A/pt not_active Application Discontinuation
- 2001-10-30 EE EEP200300212A patent/EE200300212A/xx unknown
- 2001-10-30 HU HU0400529A patent/HUP0400529A3/hu unknown
- 2001-10-30 IL IL15579501A patent/IL155795A0/xx unknown
- 2001-10-30 PT PT01994213T patent/PT1339399E/pt unknown
- 2001-10-30 MX MXPA03003960A patent/MXPA03003960A/es active IP Right Grant
- 2001-10-30 PL PL01362690A patent/PL362690A1/xx not_active Application Discontinuation
- 2001-10-30 RU RU2003116898/14A patent/RU2286769C2/ru not_active IP Right Cessation
- 2001-10-30 NZ NZ525773A patent/NZ525773A/en unknown
- 2001-10-30 KR KR1020037006212A patent/KR100720205B1/ko not_active IP Right Cessation
- 2001-10-30 CA CA002436799A patent/CA2436799C/en not_active Expired - Fee Related
- 2001-10-30 AT AT01994213T patent/ATE318590T1/de not_active IP Right Cessation
- 2001-10-30 DK DK01994213T patent/DK1339399T3/da active
- 2001-10-30 DE DE60117615T patent/DE60117615T2/de not_active Expired - Fee Related
- 2001-11-06 TW TW090127505A patent/TWI259077B/zh not_active IP Right Cessation
- 2001-11-06 AR ARP010105193A patent/AR035500A1/es not_active Application Discontinuation
-
2003
- 2003-01-21 US US10/347,714 patent/US6846816B2/en not_active Expired - Fee Related
- 2003-05-05 IS IS6806A patent/IS2457B/is unknown
- 2003-05-06 NO NO20032036A patent/NO20032036L/no not_active Application Discontinuation
- 2003-05-20 BG BG107831A patent/BG107831A/bg unknown
- 2003-06-06 HR HR20030460A patent/HRP20030460A2/hr not_active Application Discontinuation
-
2004
- 2004-12-28 US US11/024,303 patent/US7148216B2/en not_active Expired - Fee Related
-
2006
- 2006-05-19 CY CY20061100653T patent/CY1105501T1/el unknown
- 2006-12-07 US US11/635,704 patent/US20070099906A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1339399T3 (da) | Kombinationer af medikamenter (fx. chlorpromazin og pentamidin) til behandling af neoplastiske lidelser | |
DK1459750T3 (da) | (S,S)-rebexetin til behandling af fibromyalgi og andre somatoforme lidelser | |
DK1278763T3 (da) | 3-Nitrogen-6,7-dioxygensteroider og anvendelser relateret dertil | |
EP1363625A4 (en) | COMBINATIONS OF DRUGS (eg, BENZIMIDAZOLE AND PENTAMIDINE) IN THE TREATMENT OF NEOPLASTIC DISORDERS | |
ITRM20020264A1 (it) | Articolo assorbente e procedimento per la sua fabbricazione. | |
DK1268431T3 (da) | 3-Cyanoquinoliner, 3-cyano-1,6-naphthyridiner og 3-cyano-1,7-naphthyridiner som proteinkinaseinhibitorer | |
IS7003A (is) | Arómatisk súlfonhýdroxýamöt og notkun þeirra til tálmunar próteasa | |
BR8103417Y1 (pt) | aparelho para descascar. | |
IS6077A (is) | Efnasambönd og aðferðir til meðhöndlunar á asma, ofnæmi og bólgutruflunum | |
DK1404304T3 (da) | Tablet omfattende cetirizin og pseudoephedrin | |
NO991278D0 (no) | FremgangsmÕte og system for sikker, direktekoplet handel | |
FR2828491B1 (fr) | Nouvelle membrane supportee, preparation et utilisations | |
DK1530462T3 (da) | 1-phenyl-2-dimethylaminomethylcyclohexanforbindelser til behandling af depressionssymtomer. smerte og inkontinens | |
NO20033415L (no) | Alkoksylerte polyglyceroler og deres anvendelse som demulgeringsmidler | |
IS6707A (is) | Efnablanda til forvarna og meðhöndlunar á krabbameini | |
DK1086077T3 (da) | Hidtil ukendte antiestrogener, fremgangsmåde til deres fremstilling og deres farmaceutiske anvendelse | |
IS6619A (is) | S-metýl-díhýdró-siprasídón til meðhöndlunar á geðrænum kvillum og augnkvillum | |
ITMI20022425A1 (it) | Distanziatore e distanziale. | |
DK1274700T3 (da) | Dihydrobenzopyraner, dihydrobenzothiopyraner og tetrahydroquinoliner til behandling af COX-2-medierede lidelser | |
BR0103928B1 (pt) | equipamento para tratamento de efluentes e estação para tratamento de efluentes. | |
NO20026265L (no) | Nye terapeutiske molekyl¶re varianter, og anvendelser derav | |
DK200000263Y6 (da) | Bandage til behandling af tryksår, liggesår og lignede lidelser. | |
ITFG20020004A1 (it) | Procedimento di trattamento e recupero di rifiuti speciali e sanitari, finalizzato alla produzione di combustibile da rifiuto (c.d.r.). | |
ES1049844Y (es) | Engaste para piezas de joyeria y bisuteria. | |
DK1324980T3 (da) | Citrullimyciner, og fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler |